Effects of the Genetic Depletion of Polysialyltransferases on the Structure and Connectivity of Interneurons in the Adult Prefrontal Cortex.

abstract：:The development of light-sheet fluorescence microscopy (LSFM) has greatly expanded the experimental capabilities in many biological and biomedical research fields, enabling for example live studies of murine and zebrafish neural activity or of cell growth and division. The key feature of the method is the selective il...

journal_title：Frontiers in neuroanatomy

authors： Sancataldo G,Gavryusev V,de Vito G,Turrini L,Locatelli M,Fornetto C,Tiso N,Vanzi F,Silvestri L,Pavone FS

更新日期：2019-02-08 00:00:00

abstract：:Species-typical patterns of grouping have profound impacts on many aspects of physiology and behavior. However, prior to our recent studies in estrildid finches, neural mechanisms that titrate species-typical group-size preferences, independent of other aspects of social organization (e.g., mating system and parental ...

journal_title：Frontiers in neuroanatomy

authors： Goodson JL,Kingsbury MA

更新日期：2011-03-02 00:00:00

abstract：:Parkinson's disease (PD) is a neurodegenerative disorder that affects about 1.5% of the global population over 65 years of age. A hallmark feature of PD is the degeneration of the dopamine (DA) neurons in the substantia nigra pars compacta (SNc) and the consequent striatal DA deficiency. Yet, the pathogenesis of PD re...

journal_title：Frontiers in neuroanatomy

authors： Blesa J,Przedborski S

更新日期：2014-12-15 00:00:00

abstract：:Subsets of GABAergic neurons are able to maintain high frequency discharge patterns, which requires efficient replenishment of the releasable pool of GABA. Although glutamine is considered a preferred precursor of GABA, the identity of transporters involved in glutamine uptake by GABAergic neurons remains elusive. Mol...

journal_title：Frontiers in neuroanatomy

authors： Solbu TT,Bjørkmo M,Berghuis P,Harkany T,Chaudhry FA

更新日期：2010-02-08 00:00:00

abstract：:The claustrum is a narrow subcortical brain structure that resides between the striatum and insular cortex. The function of the claustrum is not fully described, and while our previous work supports a role for the claustrum in top-down cognitive control of action, other evidence suggests the claustrum may be involved ...

journal_title：Frontiers in neuroanatomy

authors： Qadir H,Krimmel SR,Mu C,Poulopoulos A,Seminowicz DA,Mathur BN

更新日期：2018-11-26 00:00:00

abstract：:Perinatal asphyxia (PA) is an obstetric complication that strongly affects the CNS. The endocannabinoid system (ECS) is a lipid transmitter system involved in several physiological processes including synaptic plasticity, neurogenesis, memory, and mood. Endocannabinoids, and other acylethanolamides (AEs) without endoc...

journal_title：Frontiers in neuroanatomy

authors： Blanco E,Galeano P,Holubiec MI,Romero JI,Logica T,Rivera P,Pavón FJ,Suarez J,Capani F,Rodríguez de Fonseca F

更新日期：2015-11-03 00:00:00

abstract：:How does the size of the glial and neuronal cells that compose brain tissue vary across brain structures and species? Our previous studies indicate that average neuronal size is highly variable, while average glial cell size is more constant. Measuring whole cell sizes in vivo, however, is a daunting task. Here we use...

journal_title：Frontiers in neuroanatomy

authors： Mota B,Herculano-Houzel S

更新日期：2014-11-12 00:00:00

abstract：:Pyramidal cells grow and mature at different rates among different cortical areas in the macaque monkey. In particular, differences across the areas have been reported in both the timing and magnitude of growth, branching, spinogenesis, and pruning in the basal dendritic trees of cells in layer III. Presently availabl...

journal_title：Frontiers in neuroanatomy

authors： Elston GN,Oga T,Okamoto T,Fujita I

更新日期：2011-07-21 00:00:00

abstract：:The artiodactyl brain has multiple levels of vascular pooling and the rostral epidural rete mirabile (RERM) at its base. The current study is the first of its kind to precisely demonstrate the arterial vasculature of the dromedary brain, utilizing a new casting method with colored latex and epoxy paint. In total, 35 f...

journal_title：Frontiers in neuroanatomy

authors： Al Aiyan A,Menon P,AlDarwich A,Almuhairi F,Alnuaimi S,Bulshawareb A,Qablan M,Shehab S

更新日期：2019-07-05 00:00:00

abstract：:Early telencephalic development involves the migration of diverse cell types that can be identified by specific molecular markers. Most prominent among them are Cajal-Retzius (CR) cells that emanate mainly from the cortical hem and to a lesser extent from rostrolateral, septal and caudo-medial regions. One additional ...

journal_title：Frontiers in neuroanatomy

authors： Frade-Pérez MD,Miquelajáuregui A,Varela-Echavarría A

更新日期：2017-11-01 00:00:00

abstract：:The neural circuits involved in mediating complex behaviors are being rapidly elucidated using various newly developed and powerful anatomical and molecular techniques, providing insights into the neural basis for anxiety disorders, depression, addiction, and dysfunctional social behaviors. Many of these behaviors and...

journal_title：Frontiers in neuroanatomy

authors： Santos FN,Pereira CW,Sánchez-Pérez AM,Otero-García M,Ma S,Gundlach AL,Olucha-Bordonau FE

更新日期：2016-04-07 00:00:00

abstract：:Expression patterns of Nkx2.1 and Islet-1 (Isl1), which encode transcription factors that are key in the regionalization of the forebrain, were analyzed by combined immunohistochemical methods in young adult specimens of two lungfishes (Neoceratodus forsteri and Protopterus dolloi) and a urodele amphibian (Pleurodeles...

journal_title：Frontiers in neuroanatomy

authors： Moreno N,López JM,Morona R,Lozano D,Jiménez S,González A

更新日期：2018-05-18 00:00:00

abstract：:Gaucher's disease (GD) is the most prevalent lysosomal storage disorder. GD is caused by homozygous mutations of the GBA1 gene, which codes for beta-glucocerebrosidase (GCase). Although GD primarily affects peripheral tissues, the presence of neurological symptoms has been reported in several GD subtypes. GBA1 mutatio...

journal_title：Frontiers in neuroanatomy

authors： Franco R,Sánchez-Arias JA,Navarro G,Lanciego JL

更新日期：2018-06-28 00:00:00

abstract：:This study presents a tool, Neuronize, for building realistic three-dimensional models of neuronal cells from the morphological information extracted through computer-aided tracing applications. Neuronize consists of a set of methods designed to build 3D neural meshes that approximate the cell membrane at different re...

journal_title：Frontiers in neuroanatomy

authors： Brito JP,Mata S,Bayona S,Pastor L,Defelipe J,Benavides-Piccione R

更新日期：2013-06-03 00:00:00

abstract：:Recent studies have supported the relation between mitochondrial functions and degenerative disorders related to ageing, such as Alzheimer's and Parkinson's diseases. Since these studies have exposed the need for detailed and high-resolution analysis of physical alterations in mitochondria, it is necessary to be able ...

journal_title：Frontiers in neuroanatomy

authors： Xiao C,Chen X,Li W,Li L,Wang L,Xie Q,Han H

更新日期：2018-11-02 00:00:00

abstract：:Over the last 60 years, the spotlight of research has periodically returned to the cerebellum as new techniques and insights have emerged. Because of its simple homogeneous structure, limited diversity of cell types and characteristic behavioral pathologies, the cerebellum is a natural home for studies of cell specifi...

journal_title：Frontiers in neuroanatomy

authors： Basson MA,Wingate RJ

更新日期：2013-09-03 00:00:00

abstract：:Imaging entire mouse brains at submicron resolution has historically been a challenging undertaking and largely confined to the province of dedicated atlasing initiatives. This has limited systematic investigations into important areas of neuroscience, such as neural circuits, brain mapping and neurodegeneration. In t...

journal_title：Frontiers in neuroanatomy

authors： Amato SP,Pan F,Schwartz J,Ragan TM

更新日期：2016-03-22 00:00:00

abstract：:Why do neurons have dendritic spines? This question-the heart of what Yuste calls "the spine problem"-presupposes that why-questions of this sort have scientific answers: that empirical findings can favor or count against claims about why neurons have spines. Here we show how such questions can receive empirical answe...

journal_title：Frontiers in neuroanatomy

authors： Malanowski S,Craver CF

更新日期：2014-09-10 00:00:00

abstract：:Emotions depend upon the integrated activity of neural networks that modulate arousal, autonomic function, motor control, and somatosensation. Brainstem nodes play critical roles in each of these networks, but prior studies of the neuroanatomic basis of emotion, particularly in the human neuropsychological literature,...

journal_title：Frontiers in neuroanatomy

authors： Venkatraman A,Edlow BL,Immordino-Yang MH

更新日期：2017-03-09 00:00:00

abstract：:The thalamocingulate tract is a key component of the Papez circuit that connects the anterior thalamic nucleus (ATN) to the cingulum bundle. While the other white matter connections, consisting of the fornix, cingulum bundle and mammillothalamic tract, were well defined in Papez's original 1937 paper, the anatomy of t...

journal_title：Frontiers in neuroanatomy

authors： Weininger J,Roman E,Tierney P,Barry D,Gallagher H,Murphy P,Levins KJ,O'Keane V,O'Hanlon E,Roddy DW

更新日期：2019-02-18 00:00:00

abstract：:The distribution of vitamin D-dependent calcium-binding protein (28 kDa calbindin) was investigated in cat lumbar and sacral spinal cord segments (L1-S3). We observed specific multi-dimensional distributions over the spinal segments for small immunopositive cells in Rexed laminae II-III and medium-to-large cells of va...

journal_title：Frontiers in neuroanatomy

authors： Merkulyeva N,Veshchitskii A,Makarov F,Gerasimenko Y,Musienko P

更新日期：2016-01-28 00:00:00

abstract：:Dendrite and dendritic spine formation are crucial for proper brain function. DISC1-binding zinc finger protein (DBZ) was first identified as a Disrupted-In-Schizophrenia1 (DISC1) binding partner. DBZ is highly expressed in the cerebral cortex of developing and adult rodents and is involved in neurite formation, cell ...

journal_title：Frontiers in neuroanatomy

authors： Koyama Y,Hattori T,Nishida T,Hori O,Tohyama M

更新日期：2015-04-30 00:00:00

abstract：:The white matter (WM) of the adult human neocortex contains the so-called "interstitial neurons". They are most numerous in the superficial WM underlying the cortical gyri, and decrease in density toward the deep WM. They are morphologically heterogeneous. A subgroup of interstitial neurons display pyramidal-cell like...

journal_title：Frontiers in neuroanatomy

authors： Suárez-Solá ML,González-Delgado FJ,Pueyo-Morlans M,Medina-Bolívar OC,Hernández-Acosta NC,González-Gómez M,Meyer G

更新日期：2009-06-09 00:00:00

abstract：:The striatum and the subthalamic nucleus (STN) are the main entry doors for extrinsic inputs to reach the basal ganglia (BG) circuitry. The cerebral cortex, thalamus and brainstem are the key sources of glutamatergic inputs to these nuclei. There is anatomical, functional and neurochemical evidence that glutamatergic ...

journal_title：Frontiers in neuroanatomy

authors： Villalba RM,Mathai A,Smith Y

更新日期：2015-09-25 00:00:00

abstract：:Dendritic spines are micron-sized protrusions that harbor the majority of excitatory synapses in the central nervous system. The head of the spine is connected to the dendritic shaft by a 50-400 nm thin membrane tube, called the spine neck, which has been hypothesized to confine biochemical and electric signals within...

journal_title：Frontiers in neuroanatomy

authors： Adrian M,Kusters R,Wierenga CJ,Storm C,Hoogenraad CC,Kapitein LC

更新日期：2014-12-04 00:00:00

abstract：:Dopamine (DA) modulates the effects of amino acid neurotransmitters (AANs), including GABA and glutamate, in motor, visual, olfactory, and reward systems (Hnasko et al., 2010; Stuber et al., 2010; Hnasko and Edwards, 2012). The results suggest that DA may play a similar modulatory role in the auditory pathways. Previo...

journal_title：Frontiers in neuroanatomy

authors： Fyk-Kolodziej BE,Shimano T,Gafoor D,Mirza N,Griffith RD,Gong TW,Holt AG

更新日期：2015-07-22 00:00:00

abstract：:When does adult hippocampal neurogenesis begin? We describe the development of the neurogenic niche in the subgranular zone (SGZ) of the hippocampal dentate gyrus. We did so from the perspective of the situation in the adult. Ontogeny of the dentate gyrus is complex and results in an ectopic neurogenic niche that life...

journal_title：Frontiers in neuroanatomy

authors： Nicola Z,Fabel K,Kempermann G

更新日期：2015-05-07 00:00:00

abstract：:Expansion microscopy and light sheet imaging (ExLSM) provide a viable alternative to existing tissue clearing and large volume imaging approaches. The analysis of intact volumes of brain tissue presents a distinct challenge in neuroscience. Recent advances in tissue clearing and light sheet microscopy have re-addresse...

journal_title：Frontiers in neuroanatomy

authors： Düring DN,Rocha MD,Dittrich F,Gahr M,Hahnloser RHR

更新日期：2019-01-31 00:00:00

abstract：:A key challenge in cortical neuroscience is to gain a comprehensive understanding of how pyramidal neuron heterogeneity across different areas and species underlies the functional specialization of individual neurons, networks, and areas. Comparative studies have been important in this endeavor, providing data relevan...

journal_title：Frontiers in neuroanatomy

authors： Luebke JI

更新日期：2017-03-07 00:00:00

abstract：:Hibernating mammals undergo torpor periods characterized by a general decrease in body temperature, metabolic rate, and brain activity accompanied by complex adaptive brain changes that appear to protect the brain from extreme conditions of hypoxia and low temperatures. These processes are accompanied by morphological...

journal_title：Frontiers in neuroanatomy

authors： León-Espinosa G,DeFelipe J,Muñoz A

更新日期：2019-11-19 00:00:00