The spine problem: finding a function for dendritic spines.

abstract：:This study was aimed at mapping the organization of the projections from the inferior olive (IO) to the ventral uvula in pigeons. The uvula is part of the vestibulocerebellum (VbC), which is involved in the processing of optic flow resulting from self-motion. As in other areas of the cerebellum, the uvula is organized...

journal_title：Frontiers in neuroanatomy

authors： Craciun I,Gutiérrez-Ibáñez C,Corfield JR,Hurd PL,Wylie DR

更新日期：2018-03-15 00:00:00

abstract：:Calcium stores in neurons are heterogeneous in compartmentalization and molecular composition. Danio rerio (zebrafish) is an animal model with a simply folded cerebellum similar in cellular organization to that of mammals. The aim of the study was to identify new endoplasmic reticulum (ER) calcium store markers in zeb...

journal_title：Frontiers in neuroanatomy

authors： Furlan S,Campione M,Murgia M,Mosole S,Argenton F,Volpe P,Nori A

更新日期：2020-04-21 00:00:00

abstract：:Musical training can induce the functional and structural changes of the hippocampus. The hippocampus is not a homogeneous structure which can be divided into anterior and posterior parts along its longitudinal axis, and the whole-brain structural covariances of anterior (aHC) and posterior hippocampus (pHC) show dist...

journal_title：Frontiers in neuroanatomy

authors： Guo P,Li Q,Wang X,Li X,Wang S,Xie Y,Xie Y,Fu Z,Zhang X,Li S

更新日期：2020-05-19 00:00:00

abstract：:Immunohistochemistry (IHC) is a valuable method for identifying discrete neurochemical molecules by the interaction of target antigens with validated antibodies tagged with a visible label (e.g., peroxidase). We have developed an immunostaining method that is highly sensitive in detection of neurochemical antigens. Ou...

journal_title：Frontiers in neuroanatomy

authors： Goto S,Morigaki R,Okita S,Nagahiro S,Kaji R

更新日期：2015-03-03 00:00:00

abstract：:The hypothalamus has been a central topic in neuroanatomy because of its important physiological functions, but its mature organization remains elusive. Deciphering its embryonic and adult organization is crucial in an evolutionary approach of the organization of the vertebrate forebrain. Here we studied the molecular...

journal_title：Frontiers in neuroanatomy

authors： Santos-Durán GN,Menuet A,Lagadec R,Mayeur H,Ferreiro-Galve S,Mazan S,Rodríguez-Moldes I,Candal E

更新日期：2015-04-08 00:00:00

abstract：:Subsets of GABAergic neurons are able to maintain high frequency discharge patterns, which requires efficient replenishment of the releasable pool of GABA. Although glutamine is considered a preferred precursor of GABA, the identity of transporters involved in glutamine uptake by GABAergic neurons remains elusive. Mol...

journal_title：Frontiers in neuroanatomy

authors： Solbu TT,Bjørkmo M,Berghuis P,Harkany T,Chaudhry FA

更新日期：2010-02-08 00:00:00

abstract：:The striatum and the subthalamic nucleus (STN) are the main entry doors for extrinsic inputs to reach the basal ganglia (BG) circuitry. The cerebral cortex, thalamus and brainstem are the key sources of glutamatergic inputs to these nuclei. There is anatomical, functional and neurochemical evidence that glutamatergic ...

journal_title：Frontiers in neuroanatomy

authors： Villalba RM,Mathai A,Smith Y

更新日期：2015-09-25 00:00:00

abstract：:The anterior cingulate cortex (ACC), surrounding the genu of the corpus callosum, plays important roles in emotional processing and is functionally divided into the dorsal, perigenual, and subgenual subregions (dACC, pgACC, and sgACC, respectively). Previous studies have suggested that the pgACC and sgACC have distinc...

journal_title：Frontiers in neuroanatomy

authors： Sakata H,Kim Y,Nejime M,Konoike N,Miyachi S,Nakamura K

更新日期：2019-07-31 00:00:00

abstract：:Expansion microscopy and light sheet imaging (ExLSM) provide a viable alternative to existing tissue clearing and large volume imaging approaches. The analysis of intact volumes of brain tissue presents a distinct challenge in neuroscience. Recent advances in tissue clearing and light sheet microscopy have re-addresse...

journal_title：Frontiers in neuroanatomy

authors： Düring DN,Rocha MD,Dittrich F,Gahr M,Hahnloser RHR

更新日期：2019-01-31 00:00:00

abstract：:The caudal region of the rodent striatum, called the tail of the striatum (TS), is a relatively small area but might have a distinct function from other striatal subregions. Recent primate studies showed that this part of the striatum has a unique function in encoding long-term value memory of visual objects for habit...

journal_title：Frontiers in neuroanatomy

authors： Jiang H,Kim HF

更新日期：2018-05-03 00:00:00

abstract：:Dual transneuronal tracing is a novel viral tracing methodology which employs two recombinant viruses, each expressing a different reporter protein. Peripheral injection of recombinant pseudorabies viruses has been used as a powerful method to define neurons that coordinate outputs to various peripheral targets of mot...

journal_title：Frontiers in neuroanatomy

authors： Ohara S,Inoue K,Yamada M,Yamawaki T,Koganezawa N,Tsutsui K,Witter MP,Iijima T

更新日期：2009-01-19 00:00:00

abstract：:Enough species have now been subject to systematic quantitative analysis of the relationship between the morphology and cellular composition of their brain that patterns begin to emerge and shed light on the evolutionary path that led to mammalian brain diversity. Based on an analysis of the shared and clade-specific ...

journal_title：Frontiers in neuroanatomy

authors： Herculano-Houzel S,Manger PR,Kaas JH

更新日期：2014-08-11 00:00:00

abstract：:A key challenge in cortical neuroscience is to gain a comprehensive understanding of how pyramidal neuron heterogeneity across different areas and species underlies the functional specialization of individual neurons, networks, and areas. Comparative studies have been important in this endeavor, providing data relevan...

journal_title：Frontiers in neuroanatomy

authors： Luebke JI

更新日期：2017-03-07 00:00:00

abstract：:Rafael Lorente de Nó, the youngest of Santiago Ramón y Cajal disciples, was one of the last Century's more influential researches in neuroscience. This assay highlights two fundamental contributions of Rafael Lorente de Nó to neurobiology: the intrinsic organization of the mammalian cerebral cortex and the basic physi...

journal_title：Frontiers in neuroanatomy

authors： Larriva-Sahd JA

更新日期：2014-12-03 00:00:00

abstract：:Choline acetyltransferase (ChAT), the enzyme synthesizing acetylcholine (ACh), has an exon-skipping splice variant which is expressed preferentially in the peripheral nervous system (PNS) and thus termed peripheral ChAT (pChAT). A rabbit antiserum previously produced against rat pChAT (rpChAT) has been used for immuno...

journal_title：Frontiers in neuroanatomy

authors： Bellier JP,Yuan PQ,Mukaisho K,Tooyama I,Taché Y,Kimura H

更新日期：2019-04-16 00:00:00

abstract：:The radial dimension expands during central nervous system development after the proliferative neuroepithelium is molecularly patterned. The process is associated with neurogenesis, radial glia scaffolding, and migration of immature neurons into the developing mantle stratum. Radial histogenetic units, defined as a de...

journal_title：Frontiers in neuroanatomy

authors： Garcia-Calero E,Puelles L

更新日期：2020-11-10 00:00:00

abstract：:Cortical networks are shaped by sensory experience and are most susceptible to modifications during critical periods characterized by enhanced plasticity at the structural and functional level. A system particularly well-studied in this context is the mammalian visual system. Plasticity has been documented for the som...

journal_title：Frontiers in neuroanatomy

authors： Gutzmann A,Ergül N,Grossmann R,Schultz C,Wahle P,Engelhardt M

更新日期：2014-03-11 00:00:00

abstract：:Human inducible pluripotent stem cells (hiPSCs) hold a large potential for disease modeling. hiPSC-derived human astrocyte and neuronal cultures permit investigations of neural signaling pathways with subcellular resolution. Combinatorial cultures, and three-dimensional (3-D) embryonic bodies (EBs) enlarge the scope o...

journal_title：Frontiers in neuroanatomy

authors： Rakotoson I,Delhomme B,Djian P,Deeg A,Brunstein M,Seebacher C,Uhl R,Ricard C,Oheim M

更新日期：2019-08-20 00:00:00

abstract：:Biological impacts of light beyond vision, i.e., non-visual functions of light, signify the need to better understand light detection (or photoreception) systems in vertebrates. Photopigments, which comprise light-absorbing chromophores bound to a variety of G-protein coupled receptor opsins, are responsible for visua...

journal_title：Frontiers in neuroanatomy

authors： Hang CY,Kitahashi T,Parhar IS

更新日期：2016-04-27 00:00:00

abstract：:Early telencephalic development involves the migration of diverse cell types that can be identified by specific molecular markers. Most prominent among them are Cajal-Retzius (CR) cells that emanate mainly from the cortical hem and to a lesser extent from rostrolateral, septal and caudo-medial regions. One additional ...

journal_title：Frontiers in neuroanatomy

authors： Frade-Pérez MD,Miquelajáuregui A,Varela-Echavarría A

更新日期：2017-11-01 00:00:00

abstract：:Gestational exposure to valproic acid (VPA) is known to cause behavioral deficits of sociability, matching similar alterations in human autism spectrum disorder (ASD). Available data are scarce on the neuromorphological changes in VPA-exposed animals. Here, we focused on alterations of the dopaminergic system, which i...

journal_title：Frontiers in neuroanatomy

authors： Ádám Á,Kemecsei R,Company V,Murcia-Ramón R,Juarez I,Gerecsei LI,Zachar G,Echevarría D,Puelles E,Martínez S,Csillag A

更新日期：2020-06-05 00:00:00

abstract：:Anatomically distinct areas within the basal ganglia encode flexible- and stable-value memories for visual objects (Hikosaka et al., 2014), but an important question remains: do they receive inputs from the same or different brain areas or neurons? To answer this question, we first located flexible and stable value-co...

journal_title：Frontiers in neuroanatomy

authors： Griggs WS,Kim HF,Ghazizadeh A,Costello MG,Wall KM,Hikosaka O

更新日期：2017-11-24 00:00:00

abstract：:Dendrite and dendritic spine formation are crucial for proper brain function. DISC1-binding zinc finger protein (DBZ) was first identified as a Disrupted-In-Schizophrenia1 (DISC1) binding partner. DBZ is highly expressed in the cerebral cortex of developing and adult rodents and is involved in neurite formation, cell ...

journal_title：Frontiers in neuroanatomy

authors： Koyama Y,Hattori T,Nishida T,Hori O,Tohyama M

更新日期：2015-04-30 00:00:00

abstract：:The claustrum is a narrow subcortical brain structure that resides between the striatum and insular cortex. The function of the claustrum is not fully described, and while our previous work supports a role for the claustrum in top-down cognitive control of action, other evidence suggests the claustrum may be involved ...

journal_title：Frontiers in neuroanatomy

authors： Qadir H,Krimmel SR,Mu C,Poulopoulos A,Seminowicz DA,Mathur BN

更新日期：2018-11-26 00:00:00

abstract：:The auditory system contains a diverse array of interconnected anatomical structures that mediate the perception of sound. The cochlear nucleus of the hindbrain serves as the initial site of convergence for auditory stimuli, while the inferior colliculus of the midbrain serves as an integration and relay station for a...

journal_title：Frontiers in neuroanatomy

authors： Brown S,Zervas M

更新日期：2017-08-22 00:00:00

abstract：:Parkinson's disease (PD) is a neurodegenerative disorder that affects about 1.5% of the global population over 65 years of age. A hallmark feature of PD is the degeneration of the dopamine (DA) neurons in the substantia nigra pars compacta (SNc) and the consequent striatal DA deficiency. Yet, the pathogenesis of PD re...

journal_title：Frontiers in neuroanatomy

authors： Blesa J,Przedborski S

更新日期：2014-12-15 00:00:00

abstract：:In rodents, sexual behavior depends on the adequate detection of sexually relevant stimuli. The olfactory bulb (OB) is a region of the adult mammalian brain undergoing constant cell renewal by continuous integration of new granular and periglomerular neurons in the accessory (AOB) and main (MOB) olfactory bulbs. The p...

journal_title：Frontiers in neuroanatomy

authors： Portillo W,Unda N,Camacho FJ,Sánchez M,Corona R,Arzate DM,Díaz NF,Paredes RG

更新日期：2012-07-06 00:00:00

abstract：:Introduction: Knowledge of the neuro-anatomical architecture of the inner ear contributes to the improvement and development of cochlear and vestibular implants. The present knowledge is mainly based on two-dimensional images (histology) or derived models that simplify the complexity of this architecture. This study i...

journal_title：Frontiers in neuroanatomy

authors： van den Boogert T,van Hoof M,Handschuh S,Glueckert R,Guinand N,Guyot JP,Kingma H,Perez-Fornos A,Seppen B,Johnson Chacko L,Schrott-Fischer A,van de Berg R

更新日期：2018-05-22 00:00:00

abstract：:Standard stereotaxic reference systems play a key role in human brain studies. Stereotaxic coordinate systems have also been developed for experimental animals including non-human primates, dogs, and rodents. However, they are lacking for other species being relevant in experimental neuroscience including sheep. Here,...

journal_title：Frontiers in neuroanatomy

authors： Nitzsche B,Frey S,Collins LD,Seeger J,Lobsien D,Dreyer A,Kirsten H,Stoffel MH,Fonov VS,Boltze J

更新日期：2015-06-04 00:00:00

abstract：:Adult born neurons in the hippocampus show species-specific differences in their numbers, the pace of their maturation and their spatial distribution. Here, we present quantitative data on adult hippocampal neurogenesis in a New World primate, the common marmoset (Callithrix jacchus) that demonstrate parts of the line...

journal_title：Frontiers in neuroanatomy

authors： Amrein I,Nosswitz M,Slomianka L,van Dijk RM,Engler S,Klaus F,Raineteau O,Azim K

更新日期：2015-06-29 00:00:00