Structural Connectivity of the Anterior Cingulate Cortex, Claustrum, and the Anterior Insula of the Mouse.

Abstract:

:The claustrum is a narrow subcortical brain structure that resides between the striatum and insular cortex. The function of the claustrum is not fully described, and while our previous work supports a role for the claustrum in top-down cognitive control of action, other evidence suggests the claustrum may be involved in detecting salient changes in the external environment. The anterior cingulate cortex (ACC) and the anterior insular (aINS) are the two major participants in the salience network of human brain regions that activate in response to salient stimuli. While bidirectional connections between the ACC and the claustrum exist from mouse to non-human primate, the aINS connectivity with claustrum remains unclear, particularly in mouse. Here, we explored structural connections of the aINS with the claustrum and ACC through adeno-associated virus neuronal tract tracer injections into the ACC and aINS of the mouse. We detected sparse projections from the claustrum to the aINS and diffuse projections from the aINS to the borders of the claustrum were observed in some cases. In contrast, the insular cortex and endopiriform nucleus surrounding the claustrum had rich interconnectivity with aINS. Additionally, we observed a modest interconnectivity between ACC and the aINS. These data support the idea that claustrum neuron responses to salient stimuli may be driven by the ACC rather than the aINS.

journal_name

Front Neuroanat

authors

Qadir H,Krimmel SR,Mu C,Poulopoulos A,Seminowicz DA,Mathur BN

doi

10.3389/fnana.2018.00100

subject

Has Abstract

pub_date

2018-11-26 00:00:00

pages

100

issn

1662-5129

journal_volume

12

pub_type

杂志文章
  • Congenital hypoplasia of the cerebellum: developmental causes and behavioral consequences.

    abstract::Over the last 60 years, the spotlight of research has periodically returned to the cerebellum as new techniques and insights have emerged. Because of its simple homogeneous structure, limited diversity of cell types and characteristic behavioral pathologies, the cerebellum is a natural home for studies of cell specifi...

    journal_title:Frontiers in neuroanatomy

    pub_type: 杂志文章,评审

    doi:10.3389/fnana.2013.00029

    authors: Basson MA,Wingate RJ

    更新日期:2013-09-03 00:00:00

  • Dopamine in the auditory brainstem and midbrain: co-localization with amino acid neurotransmitters and gene expression following cochlear trauma.

    abstract::Dopamine (DA) modulates the effects of amino acid neurotransmitters (AANs), including GABA and glutamate, in motor, visual, olfactory, and reward systems (Hnasko et al., 2010; Stuber et al., 2010; Hnasko and Edwards, 2012). The results suggest that DA may play a similar modulatory role in the auditory pathways. Previo...

    journal_title:Frontiers in neuroanatomy

    pub_type: 杂志文章

    doi:10.3389/fnana.2015.00088

    authors: Fyk-Kolodziej BE,Shimano T,Gafoor D,Mirza N,Griffith RD,Gong TW,Holt AG

    更新日期:2015-07-22 00:00:00

  • Comparative Analysis of Nkx2.1 and Islet-1 Expression in Urodele Amphibians and Lungfishes Highlights the Pattern of Forebrain Organization in Early Tetrapods.

    abstract::Expression patterns of Nkx2.1 and Islet-1 (Isl1), which encode transcription factors that are key in the regionalization of the forebrain, were analyzed by combined immunohistochemical methods in young adult specimens of two lungfishes (Neoceratodus forsteri and Protopterus dolloi) and a urodele amphibian (Pleurodeles...

    journal_title:Frontiers in neuroanatomy

    pub_type: 杂志文章

    doi:10.3389/fnana.2018.00042

    authors: Moreno N,López JM,Morona R,Lozano D,Jiménez S,González A

    更新日期:2018-05-18 00:00:00

  • Morphological changes of glutamatergic synapses in animal models of Parkinson's disease.

    abstract::The striatum and the subthalamic nucleus (STN) are the main entry doors for extrinsic inputs to reach the basal ganglia (BG) circuitry. The cerebral cortex, thalamus and brainstem are the key sources of glutamatergic inputs to these nuclei. There is anatomical, functional and neurochemical evidence that glutamatergic ...

    journal_title:Frontiers in neuroanatomy

    pub_type: 杂志文章,评审

    doi:10.3389/fnana.2015.00117

    authors: Villalba RM,Mathai A,Smith Y

    更新日期:2015-09-25 00:00:00

  • The Representation of White Matter in the Central Nervous System.

    abstract::The white matter of the central nervous system (CNS) is difficult to represent in anatomy because it is located predominantly "between" other anatomical entities. In a classic presentation, like a cross section of a brain segment, white matter is present and can be labeled adequately. Several appearances of the same e...

    journal_title:Frontiers in neuroanatomy

    pub_type: 杂志文章

    doi:10.3389/fnana.2018.00102

    authors: Baud R,Sprumont P,Ten Donkelaar HJ

    更新日期:2018-12-13 00:00:00

  • Nonapeptides and the evolution of social group sizes in birds.

    abstract::Species-typical patterns of grouping have profound impacts on many aspects of physiology and behavior. However, prior to our recent studies in estrildid finches, neural mechanisms that titrate species-typical group-size preferences, independent of other aspects of social organization (e.g., mating system and parental ...

    journal_title:Frontiers in neuroanatomy

    pub_type: 杂志文章

    doi:10.3389/fnana.2011.00013

    authors: Goodson JL,Kingsbury MA

    更新日期:2011-03-02 00:00:00

  • Origin and Migration of Olfactory Cajal-Retzius Cells.

    abstract::Early telencephalic development involves the migration of diverse cell types that can be identified by specific molecular markers. Most prominent among them are Cajal-Retzius (CR) cells that emanate mainly from the cortical hem and to a lesser extent from rostrolateral, septal and caudo-medial regions. One additional ...

    journal_title:Frontiers in neuroanatomy

    pub_type: 杂志文章

    doi:10.3389/fnana.2017.00097

    authors: Frade-Pérez MD,Miquelajáuregui A,Varela-Echavarría A

    更新日期:2017-11-01 00:00:00

  • Feed-forward and feedback projections of midbrain reticular formation neurons in the cat.

    abstract::Gaze changes involving the eyes and head are orchestrated by brainstem gaze centers found within the superior colliculus (SC), paramedian pontine reticular formation (PPRF), and medullary reticular formation (MdRF). The mesencephalic reticular formation (MRF) also plays a role in gaze. It receives a major input from t...

    journal_title:Frontiers in neuroanatomy

    pub_type: 杂志文章

    doi:10.3389/fnana.2013.00055

    authors: Perkins E,May PJ,Warren S

    更新日期:2014-01-10 00:00:00

  • Brain scaling in mammalian evolution as a consequence of concerted and mosaic changes in numbers of neurons and average neuronal cell size.

    abstract::Enough species have now been subject to systematic quantitative analysis of the relationship between the morphology and cellular composition of their brain that patterns begin to emerge and shed light on the evolutionary path that led to mammalian brain diversity. Based on an analysis of the shared and clade-specific ...

    journal_title:Frontiers in neuroanatomy

    pub_type: 杂志文章,评审

    doi:10.3389/fnana.2014.00077

    authors: Herculano-Houzel S,Manger PR,Kaas JH

    更新日期:2014-08-11 00:00:00

  • SAT1, A Glutamine Transporter, is Preferentially Expressed in GABAergic Neurons.

    abstract::Subsets of GABAergic neurons are able to maintain high frequency discharge patterns, which requires efficient replenishment of the releasable pool of GABA. Although glutamine is considered a preferred precursor of GABA, the identity of transporters involved in glutamine uptake by GABAergic neurons remains elusive. Mol...

    journal_title:Frontiers in neuroanatomy

    pub_type: 杂志文章

    doi:10.3389/neuro.05.001.2010

    authors: Solbu TT,Bjørkmo M,Berghuis P,Harkany T,Chaudhry FA

    更新日期:2010-02-08 00:00:00

  • Laminar Pattern of Projections Indicates the Hierarchical Organization of the Anterior Cingulate-Temporal Lobe Emotion System.

    abstract::The anterior cingulate cortex (ACC), surrounding the genu of the corpus callosum, plays important roles in emotional processing and is functionally divided into the dorsal, perigenual, and subgenual subregions (dACC, pgACC, and sgACC, respectively). Previous studies have suggested that the pgACC and sgACC have distinc...

    journal_title:Frontiers in neuroanatomy

    pub_type: 杂志文章

    doi:10.3389/fnana.2019.00074

    authors: Sakata H,Kim Y,Nejime M,Konoike N,Miyachi S,Nakamura K

    更新日期:2019-07-31 00:00:00

  • Histogenetic Radial Models as Aids to Understanding Complex Brain Structures: The Amygdalar Radial Model as a Recent Example.

    abstract::The radial dimension expands during central nervous system development after the proliferative neuroepithelium is molecularly patterned. The process is associated with neurogenesis, radial glia scaffolding, and migration of immature neurons into the developing mantle stratum. Radial histogenetic units, defined as a de...

    journal_title:Frontiers in neuroanatomy

    pub_type: 杂志文章

    doi:10.3389/fnana.2020.590011

    authors: Garcia-Calero E,Puelles L

    更新日期:2020-11-10 00:00:00

  • Synaptic connectivity of the cholinergic axons in the olfactory bulb of the cynomolgus monkey.

    abstract::The olfactory bulb (OB) of mammals receives cholinergic afferents from the horizontal limb of the diagonal band of Broca (HDB). At present, the synaptic connectivity of the cholinergic axons on the circuits of the OB has only been investigated in the rat. In this report, we analyze the synaptic connectivity of the cho...

    journal_title:Frontiers in neuroanatomy

    pub_type: 杂志文章

    doi:10.3389/fnana.2015.00028

    authors: Liberia T,Blasco-Ibáñez JM,Nácher J,Varea E,Lanciego JL,Crespo C

    更新日期:2015-03-17 00:00:00

  • Pío del Río-Hortega: A Pioneer in the Pathology of Central Nervous System Tumors.

    abstract::The last 140 years have seen considerable advances in knowledge of central nervous system tumors. However, the main tumor types had already been described during the early years of the twentieth century. The studies of Dr. Pío del Río Hortega have been ones of the most exhaustive histology and cytology-based studies o...

    journal_title:Frontiers in neuroanatomy

    pub_type: 杂志文章,评审

    doi:10.3389/fnana.2016.00013

    authors: Ramon Y Cajal Agüeras S

    更新日期:2016-03-01 00:00:00

  • Verification of the Cross Immunoreactivity of A60, a Mouse Monoclonal Antibody against Neuronal Nuclear Protein.

    abstract::A60, the mouse monoclonal antibody against the neuronal nuclear protein (NeuN), is the most widely used neuronal marker in neuroscience research and neuropathological assays. Previous studies identified fragments of A60-immunoprecipitated protein as Synapsin I (Syn I), suggesting the antibody will demonstrate cross im...

    journal_title:Frontiers in neuroanatomy

    pub_type: 杂志文章

    doi:10.3389/fnana.2016.00054

    authors: Mao S,Xiong G,Zhang L,Dong H,Liu B,Cohen NA,Cohen AS

    更新日期:2016-05-13 00:00:00

  • Temporal Expression of Wnt1 Defines the Competency State and Terminal Identity of Progenitors in the Developing Cochlear Nucleus and Inferior Colliculus.

    abstract::The auditory system contains a diverse array of interconnected anatomical structures that mediate the perception of sound. The cochlear nucleus of the hindbrain serves as the initial site of convergence for auditory stimuli, while the inferior colliculus of the midbrain serves as an integration and relay station for a...

    journal_title:Frontiers in neuroanatomy

    pub_type: 杂志文章

    doi:10.3389/fnana.2017.00067

    authors: Brown S,Zervas M

    更新日期:2017-08-22 00:00:00

  • Structural Covariance Changes of Anterior and Posterior Hippocampus During Musical Training in Young Adults.

    abstract::Musical training can induce the functional and structural changes of the hippocampus. The hippocampus is not a homogeneous structure which can be divided into anterior and posterior parts along its longitudinal axis, and the whole-brain structural covariances of anterior (aHC) and posterior hippocampus (pHC) show dist...

    journal_title:Frontiers in neuroanatomy

    pub_type: 杂志文章

    doi:10.3389/fnana.2020.00020

    authors: Guo P,Li Q,Wang X,Li X,Wang S,Xie Y,Xie Y,Fu Z,Zhang X,Li S

    更新日期:2020-05-19 00:00:00

  • Fast 3-D Imaging of Brain Organoids With a New Single-Objective Planar-Illumination Two-Photon Microscope.

    abstract::Human inducible pluripotent stem cells (hiPSCs) hold a large potential for disease modeling. hiPSC-derived human astrocyte and neuronal cultures permit investigations of neural signaling pathways with subcellular resolution. Combinatorial cultures, and three-dimensional (3-D) embryonic bodies (EBs) enlarge the scope o...

    journal_title:Frontiers in neuroanatomy

    pub_type: 杂志文章

    doi:10.3389/fnana.2019.00077

    authors: Rakotoson I,Delhomme B,Djian P,Deeg A,Brunstein M,Seebacher C,Uhl R,Ricard C,Oheim M

    更新日期:2019-08-20 00:00:00

  • Calsequestrins New Calcium Store Markers of Adult Zebrafish Cerebellum and Optic Tectum.

    abstract::Calcium stores in neurons are heterogeneous in compartmentalization and molecular composition. Danio rerio (zebrafish) is an animal model with a simply folded cerebellum similar in cellular organization to that of mammals. The aim of the study was to identify new endoplasmic reticulum (ER) calcium store markers in zeb...

    journal_title:Frontiers in neuroanatomy

    pub_type: 杂志文章

    doi:10.3389/fnana.2020.00015

    authors: Furlan S,Campione M,Murgia M,Mosole S,Argenton F,Volpe P,Nori A

    更新日期:2020-04-21 00:00:00

  • Anatomical Inputs From the Sensory and Value Structures to the Tail of the Rat Striatum.

    abstract::The caudal region of the rodent striatum, called the tail of the striatum (TS), is a relatively small area but might have a distinct function from other striatal subregions. Recent primate studies showed that this part of the striatum has a unique function in encoding long-term value memory of visual objects for habit...

    journal_title:Frontiers in neuroanatomy

    pub_type: 杂志文章

    doi:10.3389/fnana.2018.00030

    authors: Jiang H,Kim HF

    更新日期:2018-05-03 00:00:00

  • Contribution of pheromones processed by the main olfactory system to mate recognition in female mammals.

    abstract::Until recently it was widely believed that the ability of female mammals (with the likely exception of women) to identify and seek out a male breeding partner relied on the detection of non-volatile male pheromones by the female's vomeronasal organ (VNO) and their subsequent processing by a neural circuit that include...

    journal_title:Frontiers in neuroanatomy

    pub_type: 杂志文章

    doi:10.3389/fnana.2012.00020

    authors: Baum MJ

    更新日期:2012-06-05 00:00:00

  • Hypothesis on the dual origin of the Mammalian subplate.

    abstract::The development of the mammalian neocortex relies heavily on subplate. The proportion of this cell population varies considerably in different mammalian species. Subplate is almost undetectable in marsupials, forms a thin, but distinct layer in mouse and rat, a larger layer in carnivores and big-brained mammals as pig...

    journal_title:Frontiers in neuroanatomy

    pub_type: 杂志文章

    doi:10.3389/fnana.2011.00025

    authors: Montiel JF,Wang WZ,Oeschger FM,Hoerder-Suabedissen A,Tung WL,García-Moreno F,Holm IE,Villalón A,Molnár Z

    更新日期:2011-04-07 00:00:00

  • The Brainstem in Emotion: A Review.

    abstract::Emotions depend upon the integrated activity of neural networks that modulate arousal, autonomic function, motor control, and somatosensation. Brainstem nodes play critical roles in each of these networks, but prior studies of the neuroanatomic basis of emotion, particularly in the human neuropsychological literature,...

    journal_title:Frontiers in neuroanatomy

    pub_type: 杂志文章,评审

    doi:10.3389/fnana.2017.00015

    authors: Venkatraman A,Edlow BL,Immordino-Yang MH

    更新日期:2017-03-09 00:00:00

  • Corticotectal Projections From the Premotor or Primary Motor Cortex After Cortical Lesion or Parkinsonian Symptoms in Adult Macaque Monkeys: A Pilot Tracing Study.

    abstract::The corticotectal projections, together with the corticobulbar (corticoreticular) projections, work in parallel with the corticospinal tract (CST) to influence motoneurons in the spinal cord both directly and indirectly via the brainstem descending pathways. The tectospinal tract (TST) originates in the deep layers of...

    journal_title:Frontiers in neuroanatomy

    pub_type: 杂志文章

    doi:10.3389/fnana.2019.00050

    authors: Fregosi M,Contestabile A,Badoud S,Borgognon S,Cottet J,Brunet JF,Bloch J,Schwab ME,Rouiller EM

    更新日期:2019-05-22 00:00:00

  • Flexible and Stable Value Coding Areas in Caudate Head and Tail Receive Anatomically Distinct Cortical and Subcortical Inputs.

    abstract::Anatomically distinct areas within the basal ganglia encode flexible- and stable-value memories for visual objects (Hikosaka et al., 2014), but an important question remains: do they receive inputs from the same or different brain areas or neurons? To answer this question, we first located flexible and stable value-co...

    journal_title:Frontiers in neuroanatomy

    pub_type: 杂志文章

    doi:10.3389/fnana.2017.00106

    authors: Griggs WS,Kim HF,Ghazizadeh A,Costello MG,Wall KM,Hikosaka O

    更新日期:2017-11-24 00:00:00

  • A Novel Antiserum Against a Predicted Human Peripheral Choline Acetyltransferase (hpChAT) for Labeling Neuronal Structures in Human Colon.

    abstract::Choline acetyltransferase (ChAT), the enzyme synthesizing acetylcholine (ACh), has an exon-skipping splice variant which is expressed preferentially in the peripheral nervous system (PNS) and thus termed peripheral ChAT (pChAT). A rabbit antiserum previously produced against rat pChAT (rpChAT) has been used for immuno...

    journal_title:Frontiers in neuroanatomy

    pub_type: 杂志文章

    doi:10.3389/fnana.2019.00037

    authors: Bellier JP,Yuan PQ,Mukaisho K,Tooyama I,Taché Y,Kimura H

    更新日期:2019-04-16 00:00:00

  • GABAergic Projections to the Oculomotor Nucleus in the Goldfish (carassius Auratus).

    abstract::The mammalian oculomotor nucleus receives a strong γ-aminobutyric acid (GABA)ergic synaptic input, whereas such projections have rarely been reported in fish. In order to determine whether this synaptic organization is preserved across vertebrates, we investigated the GABAergic projections to the oculomotor nucleus in...

    journal_title:Frontiers in neuroanatomy

    pub_type: 杂志文章

    doi:10.3389/fnana.2011.00007

    authors: Luque MA,Torres-Torrelo J,Carrascal L,Torres B,Herrero L

    更新日期:2011-02-04 00:00:00

  • Gestational Exposure to Sodium Valproate Disrupts Fasciculation of the Mesotelencephalic Dopaminergic Tract, With a Selective Reduction of Dopaminergic Output From the Ventral Tegmental Area.

    abstract::Gestational exposure to valproic acid (VPA) is known to cause behavioral deficits of sociability, matching similar alterations in human autism spectrum disorder (ASD). Available data are scarce on the neuromorphological changes in VPA-exposed animals. Here, we focused on alterations of the dopaminergic system, which i...

    journal_title:Frontiers in neuroanatomy

    pub_type: 杂志文章

    doi:10.3389/fnana.2020.00029

    authors: Ádám Á,Kemecsei R,Company V,Murcia-Ramón R,Juarez I,Gerecsei LI,Zachar G,Echevarría D,Puelles E,Martínez S,Csillag A

    更新日期:2020-06-05 00:00:00

  • The dendritic spine story: an intriguing process of discovery.

    abstract::Dendritic spines are key components of a variety of microcircuits and they represent the majority of postsynaptic targets of glutamatergic axon terminals in the brain. The present article will focus on the discovery of dendritic spines, which was possible thanks to the application of the Golgi technique to the study o...

    journal_title:Frontiers in neuroanatomy

    pub_type: 杂志文章,评审

    doi:10.3389/fnana.2015.00014

    authors: DeFelipe J

    更新日期:2015-03-05 00:00:00

  • Validation of In utero Tractography of Human Fetal Commissural and Internal Capsule Fibers with Histological Structure Tensor Analysis.

    abstract::Diffusion tensor imaging (DTI) and tractography offer the unique possibility to visualize the developing white matter macroanatomy of the human fetal brain in vivo and in utero and are currently under investigation for their potential use in the diagnosis of developmental pathologies of the human central nervous syste...

    journal_title:Frontiers in neuroanatomy

    pub_type: 杂志文章

    doi:10.3389/fnana.2015.00164

    authors: Mitter C,Jakab A,Brugger PC,Ricken G,Gruber GM,Bettelheim D,Scharrer A,Langs G,Hainfellner JA,Prayer D,Kasprian G

    更新日期:2015-12-24 00:00:00