Abstract:
:Until recently it was widely believed that the ability of female mammals (with the likely exception of women) to identify and seek out a male breeding partner relied on the detection of non-volatile male pheromones by the female's vomeronasal organ (VNO) and their subsequent processing by a neural circuit that includes the accessory olfactory bulb (AOB), vomeronasal amygdala, and hypothalamus. Emperical data are reviewed in this paper that demonstrate the detection of volatile pheromones by the main olfactory epithelium (MOE) of female mice which, in turn, leads to the activation of a population of glomeruli and abutting mitral cells in the main olfactory bulb (MOB). Anatomical results along with functional neuroanatomical data demonstrate that some of these MOB mitral cells project to the vomeronasal amygdala. These particular MOB mitral cells were selectively activated (i.e., expressed Fos protein) by exposure to male as opposed to female urinary volatiles. A similar selectivity to opposite sex urinary volatiles was also seen in mitral cells of the AOB of female mice. Behavioral data from female mouse, ferret, and human are reviewed that implicate the main olfactory system, in some cases interacting with the accessory olfactory system, in mate recognition.
journal_name
Front Neuroanatjournal_title
Frontiers in neuroanatomyauthors
Baum MJdoi
10.3389/fnana.2012.00020subject
Has Abstractpub_date
2012-06-05 00:00:00pages
20issn
1662-5129journal_volume
6pub_type
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journal_title:Frontiers in neuroanatomy
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journal_title:Frontiers in neuroanatomy
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journal_title:Frontiers in neuroanatomy
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doi:10.3389/fnana.2012.00025
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journal_title:Frontiers in neuroanatomy
pub_type: 杂志文章,评审
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journal_title:Frontiers in neuroanatomy
pub_type: 杂志文章
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