Flexible Multi-Beam Light-Sheet Fluorescence Microscope for Live Imaging Without Striping Artifacts.

abstract：:In human prefrontal cortex (PFC), ~85% of γ-aminobutyric acid (GABA)-expressing neurons can be subdivided into non-overlapping groups by the presence of calbindin (CB), calretinin (CR) or parvalbumin (PV). Substantial research has focused on the differences in the laminar locations of the cells bodies of these neurons...

journal_title：Frontiers in neuroanatomy

authors： Fish KN,Rocco BR,Lewis DA

更新日期：2018-02-16 00:00:00

abstract：:Biological impacts of light beyond vision, i.e., non-visual functions of light, signify the need to better understand light detection (or photoreception) systems in vertebrates. Photopigments, which comprise light-absorbing chromophores bound to a variety of G-protein coupled receptor opsins, are responsible for visua...

journal_title：Frontiers in neuroanatomy

authors： Hang CY,Kitahashi T,Parhar IS

更新日期：2016-04-27 00:00:00

abstract：:Most studies in mammals and birds have demonstrated common patterns of hypothalamic development highlighted by the combination of developmental regulatory genes (genoarchitecture), supporting the notion of the hypothalamus as a component of the secondary prosencephalon, topologically rostral to the diencephalon. In ou...

journal_title：Frontiers in neuroanatomy

authors： Domínguez L,González A,Moreno N

更新日期：2015-02-03 00:00:00

abstract：:Dendritic spines are key components of a variety of microcircuits and they represent the majority of postsynaptic targets of glutamatergic axon terminals in the brain. The present article will focus on the discovery of dendritic spines, which was possible thanks to the application of the Golgi technique to the study o...

journal_title：Frontiers in neuroanatomy

authors： DeFelipe J

更新日期：2015-03-05 00:00:00

abstract：:Polysialic acid (polySia) is a complex sugar that in the nervous system appears mainly as a posttranslational modification of the neural cell adhesion molecule (NCAM). PolySia plays important roles during brain development, but also in its plasticity during adulthood. Two polysialyltransferases (polyST), ST8SIA2 and S...

journal_title：Frontiers in neuroanatomy

authors： Curto Y,Alcaide J,Röckle I,Hildebrandt H,Nacher J

更新日期：2019-02-06 00:00:00

abstract：:This study presents a tool, Neuronize, for building realistic three-dimensional models of neuronal cells from the morphological information extracted through computer-aided tracing applications. Neuronize consists of a set of methods designed to build 3D neural meshes that approximate the cell membrane at different re...

journal_title：Frontiers in neuroanatomy

authors： Brito JP,Mata S,Bayona S,Pastor L,Defelipe J,Benavides-Piccione R

更新日期：2013-06-03 00:00:00

abstract：:Non-invasive in vivo neuroimaging techniques provide a wide array of possibilities to study human brain function. A number of approaches are available that improve our understanding of the anatomical location of brain activation patterns, including the development of probabilistic conversion tools to register individu...

journal_title：Frontiers in neuroanatomy

authors： Alkemade A,Groot JM,Forstmann BU

更新日期：2018-12-05 00:00:00

abstract：:Why do neurons have dendritic spines? This question-the heart of what Yuste calls "the spine problem"-presupposes that why-questions of this sort have scientific answers: that empirical findings can favor or count against claims about why neurons have spines. Here we show how such questions can receive empirical answe...

journal_title：Frontiers in neuroanatomy

authors： Malanowski S,Craver CF

更新日期：2014-09-10 00:00:00

abstract：:Huntington's Disease (HD) is the most frequent neurodegenerative disease caused by an expansion of polyglutamines (CAG). The main clinical manifestations of HD are chorea, cognitive impairment, and psychiatric disorders. The transmission of HD is autosomal dominant with a complete penetrance. HD has a single genetic c...

journal_title：Frontiers in neuroanatomy

authors： Roze E,Cahill E,Martin E,Bonnet C,Vanhoutte P,Betuing S,Caboche J

更新日期：2011-08-23 00:00:00

abstract：:Ketamine, a known antagonist of N-methyl-D-aspartic (NMDA) glutamate receptors, had been used as an anesthetic particularly for pediatric or for cardiac patients. Unfortunately, ketamine has become an abusive drug in many parts of the world while chronic and prolonged usage led to damages of many organs including the ...

journal_title：Frontiers in neuroanatomy

authors： Wang C,Zheng D,Xu J,Lam W,Yew DT

更新日期：2013-07-17 00:00:00

abstract：:Sevoflurane is widely used in adult and pediatric patients during clinical surgeries. Although studies have shown that exposure to sevoflurane impairs solfactory memory after an operation, the neuropathological changes underlying this effect are not clear. This study detected the effect of sevoflurane exposure on the ...

journal_title：Frontiers in neuroanatomy

authors： Yang J,Chen J,Cai G,Lu R,Sun T,Luo T,Wu S,Ling S

更新日期：2016-06-24 00:00:00

abstract：:Hibernating mammals undergo torpor periods characterized by a general decrease in body temperature, metabolic rate, and brain activity accompanied by complex adaptive brain changes that appear to protect the brain from extreme conditions of hypoxia and low temperatures. These processes are accompanied by morphological...

journal_title：Frontiers in neuroanatomy

authors： León-Espinosa G,DeFelipe J,Muñoz A

更新日期：2019-11-19 00:00:00

abstract：:The anterior cingulate cortex (ACC), surrounding the genu of the corpus callosum, plays important roles in emotional processing and is functionally divided into the dorsal, perigenual, and subgenual subregions (dACC, pgACC, and sgACC, respectively). Previous studies have suggested that the pgACC and sgACC have distinc...

journal_title：Frontiers in neuroanatomy

authors： Sakata H,Kim Y,Nejime M,Konoike N,Miyachi S,Nakamura K

更新日期：2019-07-31 00:00:00

abstract：:An increasing number of applications use the postnatal piglet model in neuroimaging studies, however, these are based primarily on T1 weighted image templates. There is a growing need for a multimodal structural brain template for a comprehensive depiction of the piglet brain, particularly given the growing applicatio...

journal_title：Frontiers in neuroanatomy

authors： Zhong J,Chen DQ,Walker M,Waspe A,Looi T,Piorkowska K,Drake JM,Hodaie M

更新日期：2016-09-27 00:00:00

abstract：:Cortical networks are shaped by sensory experience and are most susceptible to modifications during critical periods characterized by enhanced plasticity at the structural and functional level. A system particularly well-studied in this context is the mammalian visual system. Plasticity has been documented for the som...

journal_title：Frontiers in neuroanatomy

authors： Gutzmann A,Ergül N,Grossmann R,Schultz C,Wahle P,Engelhardt M

更新日期：2014-03-11 00:00:00

abstract：:This study was aimed at mapping the organization of the projections from the inferior olive (IO) to the ventral uvula in pigeons. The uvula is part of the vestibulocerebellum (VbC), which is involved in the processing of optic flow resulting from self-motion. As in other areas of the cerebellum, the uvula is organized...

journal_title：Frontiers in neuroanatomy

authors： Craciun I,Gutiérrez-Ibáñez C,Corfield JR,Hurd PL,Wylie DR

更新日期：2018-03-15 00:00:00

abstract：:In rodents, sexual behavior depends on the adequate detection of sexually relevant stimuli. The olfactory bulb (OB) is a region of the adult mammalian brain undergoing constant cell renewal by continuous integration of new granular and periglomerular neurons in the accessory (AOB) and main (MOB) olfactory bulbs. The p...

journal_title：Frontiers in neuroanatomy

authors： Portillo W,Unda N,Camacho FJ,Sánchez M,Corona R,Arzate DM,Díaz NF,Paredes RG

更新日期：2012-07-06 00:00:00

abstract：:Previous developmental studies of the thalamus (alar part of the diencephalic prosomere p2) have defined the molecular basis for the acquisition of the thalamic competence (preparttening), the subsequent formation of the secondary organizer in the zona limitans intrathalamica, and the early specification of two antero...

journal_title：Frontiers in neuroanatomy

authors： Bandín S,Morona R,González A

更新日期：2015-08-10 00:00:00

abstract：:Gaze changes involving the eyes and head are orchestrated by brainstem gaze centers found within the superior colliculus (SC), paramedian pontine reticular formation (PPRF), and medullary reticular formation (MdRF). The mesencephalic reticular formation (MRF) also plays a role in gaze. It receives a major input from t...

journal_title：Frontiers in neuroanatomy

authors： Perkins E,May PJ,Warren S

更新日期：2014-01-10 00:00:00

abstract：:Diffusion tensor imaging (DTI) and tractography offer the unique possibility to visualize the developing white matter macroanatomy of the human fetal brain in vivo and in utero and are currently under investigation for their potential use in the diagnosis of developmental pathologies of the human central nervous syste...

journal_title：Frontiers in neuroanatomy

authors： Mitter C,Jakab A,Brugger PC,Ricken G,Gruber GM,Bettelheim D,Scharrer A,Langs G,Hainfellner JA,Prayer D,Kasprian G

更新日期：2015-12-24 00:00:00

abstract：:The striatum and the subthalamic nucleus (STN) are the main entry doors for extrinsic inputs to reach the basal ganglia (BG) circuitry. The cerebral cortex, thalamus and brainstem are the key sources of glutamatergic inputs to these nuclei. There is anatomical, functional and neurochemical evidence that glutamatergic ...

journal_title：Frontiers in neuroanatomy

authors： Villalba RM,Mathai A,Smith Y

更新日期：2015-09-25 00:00:00

abstract：:Dendrite and dendritic spine formation are crucial for proper brain function. DISC1-binding zinc finger protein (DBZ) was first identified as a Disrupted-In-Schizophrenia1 (DISC1) binding partner. DBZ is highly expressed in the cerebral cortex of developing and adult rodents and is involved in neurite formation, cell ...

journal_title：Frontiers in neuroanatomy

authors： Koyama Y,Hattori T,Nishida T,Hori O,Tohyama M

更新日期：2015-04-30 00:00:00

abstract：:Enough species have now been subject to systematic quantitative analysis of the relationship between the morphology and cellular composition of their brain that patterns begin to emerge and shed light on the evolutionary path that led to mammalian brain diversity. Based on an analysis of the shared and clade-specific ...

journal_title：Frontiers in neuroanatomy

authors： Herculano-Houzel S,Manger PR,Kaas JH

更新日期：2014-08-11 00:00:00

abstract：:Cortical calretinin (CR)-expressing interneurons represent a heterogeneous subpopulation of about 10-30% of GABAergic interneurons, which altogether total ca. 12-20% of all cortical neurons. In the rodent neocortex, CR cells display different somatodendritic morphologies ranging from bipolar to multipolar but the bipo...

journal_title：Frontiers in neuroanatomy

authors： Cauli B,Zhou X,Tricoire L,Toussay X,Staiger JF

更新日期：2014-06-24 00:00:00

abstract：:Pyramidal cells grow and mature at different rates among different cortical areas in the macaque monkey. In particular, differences across the areas have been reported in both the timing and magnitude of growth, branching, spinogenesis, and pruning in the basal dendritic trees of cells in layer III. Presently availabl...

journal_title：Frontiers in neuroanatomy

authors： Elston GN,Oga T,Okamoto T,Fujita I

更新日期：2011-07-21 00:00:00

abstract：:Expansion microscopy and light sheet imaging (ExLSM) provide a viable alternative to existing tissue clearing and large volume imaging approaches. The analysis of intact volumes of brain tissue presents a distinct challenge in neuroscience. Recent advances in tissue clearing and light sheet microscopy have re-addresse...

journal_title：Frontiers in neuroanatomy

authors： Düring DN,Rocha MD,Dittrich F,Gahr M,Hahnloser RHR

更新日期：2019-01-31 00:00:00

abstract：:Despite many structural and functional aspects of the brain organization have been extensively studied in neuroscience, we are still far from a clear understanding of the intricate structure-function interactions occurring in the multi-layered brain architecture, where billions of different neurons are involved. Altho...

journal_title：Frontiers in neuroanatomy

authors： Ullo S,Nieus TR,Sona D,Maccione A,Berdondini L,Murino V

更新日期：2014-11-20 00:00:00

abstract：:The claustrum is a narrow subcortical brain structure that resides between the striatum and insular cortex. The function of the claustrum is not fully described, and while our previous work supports a role for the claustrum in top-down cognitive control of action, other evidence suggests the claustrum may be involved ...

journal_title：Frontiers in neuroanatomy

authors： Qadir H,Krimmel SR,Mu C,Poulopoulos A,Seminowicz DA,Mathur BN

更新日期：2018-11-26 00:00:00

abstract：:Carnivorans are a diverse group of mammals that includes carnivorous, omnivorous and herbivorous, domesticated and wild species, with a large range of brain sizes. Carnivory is one of several factors expected to be cognitively demanding for carnivorans due to a requirement to outsmart larger prey. On the other hand, l...

journal_title：Frontiers in neuroanatomy

authors： Jardim-Messeder D,Lambert K,Noctor S,Pestana FM,de Castro Leal ME,Bertelsen MF,Alagaili AN,Mohammad OB,Manger PR,Herculano-Houzel S

更新日期：2017-12-12 00:00:00

abstract：:Calcium stores in neurons are heterogeneous in compartmentalization and molecular composition. Danio rerio (zebrafish) is an animal model with a simply folded cerebellum similar in cellular organization to that of mammals. The aim of the study was to identify new endoplasmic reticulum (ER) calcium store markers in zeb...

journal_title：Frontiers in neuroanatomy

authors： Furlan S,Campione M,Murgia M,Mosole S,Argenton F,Volpe P,Nori A

更新日期：2020-04-21 00:00:00