Structural Plasticity on the SpiNNaker Many-Core Neuromorphic System.

abstract：:Calcium imaging using fluorescent reporters is the most widely used optical approach to investigate activity in intact neuronal circuits with single-cell resolution. Calcium signals, however, are often difficult to interpret, especially if the desired output quantity is membrane voltage or instantaneous firing rates. ...

journal_title：Frontiers in neuroscience

authors： Moreaux L,Laurent G

更新日期：2008-12-15 00:00:00

abstract：:Anorexia nervosa (AN) has the highest mortality rate of any psychiatric disease, yet available pharmacological treatments are largely ineffective due, in part, to an inadequate understanding of the neurobiological drivers that underpin the condition. The recent resurgence of research into the clinical applications of ...

journal_title：Frontiers in neuroscience

authors： Foldi CJ,Liknaitzky P,Williams M,Oldfield BJ

更新日期：2020-02-04 00:00:00

abstract：:Neuroscientific imaging evidence (NIE) has become an integral part of the criminal justice system in the United States. However, in most legal cases, NIE is submitted and used only to mitigate penalties because the court does not recognize it as substantial evidence, considering its lack of reliability. Nevertheless, ...

journal_title：Frontiers in neuroscience

authors： Jun J,Yoo S

更新日期：2018-03-01 00:00:00

abstract：:Background: Physiological responses related to manual therapy (MT) treatment have been investigated over decades using various animal models. However, these studies have not been compiled and their collective findings appraised. The purpose of this scoping review was to assess current scientific knowledge on the physi...

journal_title：Frontiers in neuroscience

authors： Lima CR,Martins DF,Reed WR

更新日期：2020-05-08 00:00:00

abstract：:Information processing in the cerebral cortex requires the activation of diverse neurons across layers and columns, which are established through the coordinated production of distinct neuronal subtypes and their placement along the three-dimensional axis. Over recent years, our knowledge of the regulatory mechanisms ...

journal_title：Frontiers in neuroscience

authors： Toma K,Hanashima C

更新日期：2015-08-11 00:00:00

abstract：:This work presents the design, implementation, and evaluation of a P300-based brain-machine interface (BMI) developed to control a robotic hand-orthosis. The purpose of this system is to assist patients with amyotrophic lateral sclerosis (ALS) who cannot open and close their hands by themselves. The user of this inter...

journal_title：Frontiers in neuroscience

authors： Delijorge J,Mendoza-Montoya O,Gordillo JL,Caraza R,Martinez HR,Antelis JM

更新日期：2020-11-27 00:00:00

abstract：:Studies of delay discounting typically have involved choices between smaller, immediate outcomes and larger, delayed outcomes. In a study of delay discounting in humans, Green et al. (2005) added a period of time prior to both outcomes, creating a delay common to both. They found that the subjective value of the more ...

journal_title：Frontiers in neuroscience

authors： Calvert AL,Green L,Myerson J

更新日期：2011-08-17 00:00:00

abstract：:A well-defined granular layer 4 is a defining cytoarchitectonic feature associated with sensory areas of mammalian cerebral cortex, and one with hodological significance: the local axons ascending from cells in thalamorecipient layer 4 and connecting to layer 2/3 pyramidal neurons form a major feedforward excitatory i...

journal_title：Frontiers in neuroscience

authors： Shepherd GM

更新日期：2009-12-15 00:00:00

abstract：:Gilles de la Tourette Sydrome (TS) is a childhood onset neurodevelopmental disorder, characterized phenotypically by the presence of multiple motor and vocal tics. It is often accompanied by multiple psychiatric comorbidities, with Attention Deficit/Hyperactivity Disorder (ADHD) among the most common. The extensive co...

journal_title：Frontiers in neuroscience

authors： Tsetsos F,Padmanabhuni SS,Alexander J,Karagiannidis I,Tsifintaris M,Topaloudi A,Mantzaris D,Georgitsi M,Drineas P,Paschou P

更新日期：2016-07-22 00:00:00

abstract：:Stroke patients often use trunk to compensate for impaired upper limb motor function during upper limb rehabilitation training, which results in a reduced rehabilitation training effect. Detecting trunk compensations can improve the effect of rehabilitation training. This study investigates the feasibility of a surfac...

journal_title：Frontiers in neuroscience

authors： Ma K,Chen Y,Zhang X,Zheng H,Yu S,Cai S,Xie L

更新日期：2019-11-21 00:00:00

abstract：:Hormonal contraceptives are on the market for more than 50 years and used by 100 million women worldwide. However, while endogenous steroids have been convincingly associated with change in brain structure, function and cognitive performance, the effects of synthetic steroids contained in hormonal contraceptives on br...

journal_title：Frontiers in neuroscience

authors： Pletzer BA,Kerschbaum HH

更新日期：2014-08-21 00:00:00

abstract：:A growing understanding of music therapy with patients with disorders of consciousness (DOC) has developed from observing behavioral changes and using these to gain new ways of experiencing this research environment and setting. Neuroscience provides further insight into the effects of music therapy; however, various ...

journal_title：Frontiers in neuroscience

authors： Vogl J,Heine AM,Steinhoff N,Weiss K,Tucek G

更新日期：2015-08-04 00:00:00

abstract：:Monoamine oxidase-A (MAO-A) and MAO-B have both been implicated in the pathology of Alzheimer disease (AD). We examined 60 autopsied control and AD donor brain samples to determine how well MAO function aligned with two major risk factors for AD, namely sex and APOE ε4 status. MAO-A activity was increased in AD cortic...

journal_title：Frontiers in neuroscience

authors： Quartey MO,Nyarko JNK,Pennington PR,Heistad RM,Klassen PC,Baker GB,Mousseau DD

更新日期：2018-06-26 00:00:00

abstract：:Blood-oxygen-level dependent (BOLD) signals are widely used in functional magnetic resonance imaging (fMRI) as a proxy measure of brain activation. However, because these signals are blood-related, they are also influenced by other physiological processes. This is especially true in resting state fMRI, during which no...

journal_title：Frontiers in neuroscience

authors： Tong Y,Hocke LM,Lindsey KP,Erdoğan SB,Vitaliano G,Caine CE,Frederick Bd

更新日期：2016-06-30 00:00:00

abstract：:Schizophrenia is a severe neuropsychiatric disorder with persistence of symptoms throughout adult life in most of the affected patients. This unfavorable course is associated with multiple episodes and residual symptoms, mainly negative symptoms and cognitive deficits. The neural diathesis-stress model proposes that p...

journal_title：Frontiers in neuroscience

authors： Popovic D,Schmitt A,Kaurani L,Senner F,Papiol S,Malchow B,Fischer A,Schulze TG,Koutsouleris N,Falkai P

更新日期：2019-03-21 00:00:00

abstract：:The field of neuroimaging has embraced the need for sharing and collaboration. Data sharing mandates from public funding agencies and major journal publishers have spurred the development of data repositories and neuroinformatics consortia. However, efficient and effective data sharing still faces several hurdles. For...

journal_title：Frontiers in neuroscience

authors： Plis SM,Sarwate AD,Wood D,Dieringer C,Landis D,Reed C,Panta SR,Turner JA,Shoemaker JM,Carter KW,Thompson P,Hutchison K,Calhoun VD

更新日期：2016-08-19 00:00:00

abstract：:Transsynaptic connections enabling cell-cell adhesion and cellular communication are a vital part of synapse formation, maintenance and function. A recently discovered interaction between the Adhesion GPCRs Latrophilins and the type II single transmembrane proteins Teneurins at mammalian synapses is vital for synapse ...

journal_title：Frontiers in neuroscience

authors： Schöneberg T,Prömel S

更新日期：2019-03-12 00:00:00

abstract：:The Artificial Intelligence (AI) revolution foretold of during the 1960s is well underway in the second decade of the twenty first century. Its period of phenomenal growth likely lies ahead. AI-operated machines and technologies will extend the reach of Homo sapiens far beyond the biological constraints imposed by evo...

journal_title：Frontiers in neuroscience

authors： Krichmar JL,Severa W,Khan MS,Olds JL

更新日期：2019-06-27 00:00:00

abstract：Objective:Magnetic resonance-guided focused ultrasound surgery (MRgFUS) lesioning is a new treatment for brain disorders. However, the skull is a major barrier of ultrasound sonication in MRgFUS because it has an irregular surface and varies its size and shape among individuals. We recently developed the concept of sku...

journal_title：Frontiers in neuroscience

authors： Chang KW,Rachmilevitch I,Chang WS,Jung HH,Zadicario E,Prus O,Chang JW

更新日期：2021-01-12 00:00:00

abstract：:Introduction: Spasticity is a typical motor disorder in patients affected by stroke. Typically post-stroke rehabilitation consists of repetition of mobilization exercises on impaired limbs, aimed to reduce muscle hypertonia and mitigate spastic reflexes. It is currently strongly debated if the treatment's effectivenes...

journal_title：Frontiers in neuroscience

authors： Crea S,Cempini M,Mazzoleni S,Carrozza MC,Posteraro F,Vitiello N

更新日期：2017-05-12 00:00:00

abstract：:The default mode network (DMN) has been used to study disruptions of functional connectivity in a wide variety of psychiatric and neurological conditions, including posttraumatic stress disorder (PTSD). Studies indicate that the serotonin system exerts a modulatory influence on DMN connectivity; however, no prior stud...

journal_title：Frontiers in neuroscience

authors： Miller MW,Sperbeck E,Robinson ME,Sadeh N,Wolf EJ,Hayes JP,Logue M,Schichman SA,Stone A,Milberg W,McGlinchey R

更新日期：2016-06-28 00:00:00

abstract：:Analog arrays are a promising emerging hardware technology with the potential to drastically speed up deep learning. Their main advantage is that they employ analog circuitry to compute matrix-vector products in constant time, irrespective of the size of the matrix. However, ConvNets map very unfavorably onto analog a...

journal_title：Frontiers in neuroscience

authors： Rasch MJ,Gokmen T,Rigotti M,Haensch W

更新日期：2019-07-30 00:00:00

abstract：:Ischemic stroke places an increasing burden on individuals, families, and societies around the world. However, effective therapies or drugs for ischemic stroke are lacking. Therefore, animal models mimicking ischemic stroke in humans are of great value for preclinical experiments. middle cerebral artery occlusion (MCA...

journal_title：Frontiers in neuroscience

authors： Shi XF,Ai H,Lu W,Cai F

更新日期：2019-02-12 00:00:00

abstract：:The melanocortin receptors (MCRs) are a gene family in the rhodopsin class of G protein-coupled receptors. Based on the analysis of several metazoan genome databases it appears that the MCRs are only found in chordates. The presence of five genes in the family (i.e., mc1r, mc2r, mc3r, mc4r, mc5r) in representatives of...

journal_title：Frontiers in neuroscience

authors： Dores RM

更新日期：2013-04-10 00:00:00

abstract：:Overview- One hundred and ten years since its first description Alzheimer's disease (AD) still retains its prominent status: (i) as the industrialized world's number one cause of age-related intellectual impairment and cognitive decline; (ii) as this country's most rapidly expanding socioeconomic and healthcare concer...

journal_title：Frontiers in neuroscience

authors： Zhao Y,Alexandrov PN,Lukiw WJ

更新日期：2016-02-25 00:00:00

abstract：:Brain functional connectivity network (BFCN) analysis has been widely used in the diagnosis of mental disorders, such as schizophrenia. In BFCN methods, brain network construction is one of the core tasks due to its great influence on the diagnosis result. Most of the existing BFCN construction methods only consider t...

journal_title：Frontiers in neuroscience

authors： Zhu Q,Li H,Huang J,Xu X,Guan D,Zhang D

更新日期：2019-06-14 00:00:00

abstract：:Numerous studies have been performed to examine gene expression patterns in the rodent hippocampus in the kindling model of epilepsy. However, recent reviews of this literature have revealed limited agreement among studies. Because this conclusion was based on retrospective comparison of reported "hit lists" from indi...

journal_title：Frontiers in neuroscience

authors： Rogic S,Pavlidis P

更新日期：2009-09-15 00:00:00

abstract：:Although the interplay between endogenous opioids and dopamine (DA) in the basal ganglia (BG) is known to underlie diverse motor functions, few studies exist on their role in modulating speech and vocalization. Vocal impairment is a common symptom of Parkinson's disease (PD), wherein DA depletion affects striosomes ri...

journal_title：Frontiers in neuroscience

authors： Kumar S,Mohapatra AN,Sharma HP,Singh UA,Kambi NA,Velpandian T,Rajan R,Iyengar S

更新日期：2019-07-03 00:00:00

abstract：:A vast literature implicates the ventral striatum in the processing of reward-related information and in mediating the impact of such information on behavior. It is characterized by heterogeneity at the local circuit, connectivity, and functional levels. A tool for dissecting this complex structure that has received r...

journal_title：Frontiers in neuroscience

authors： van der Meer MA,Kalenscher T,Lansink CS,Pennartz CM,Berke JD,Redish AD

更新日期：2010-09-15 00:00:00

abstract：:Drug addiction is a chronic disease characterized by recurring episodes of abstinence and relapse. The precise mechanisms underlying this pattern are yet to be elucidated, but stress is thought to be a major factor in relapse. Recently, we reported that rats under withdrawal and exposed to a mild chronic stressor, pro...

journal_title：Frontiers in neuroscience

authors： Sedki F,Abbas Z,Angelis S,Martin J,D'Cunha T,Shalev U

更新日期：2013-06-06 00:00:00