Meta-Analysis of Tourette Syndrome and Attention Deficit Hyperactivity Disorder Provides Support for a Shared Genetic Basis.

abstract：:The utility of premovement electroencephalography (EEG) for decoding movement intention during a reaching task has been demonstrated. However, the kind of information the brain represents regarding the intended target during movement preparation remains unknown. In the present study, we investigated which movement par...

journal_title：Frontiers in neuroscience

authors： Kim H,Yoshimura N,Koike Y

更新日期：2019-11-01 00:00:00

abstract：:Auditory recognition memory in non-human primates differs from recognition memory in other sensory systems. Monkeys learn the rule for visual and tactile delayed matching-to-sample within a few sessions, and then show one-trial recognition memory lasting 10-20 min. In contrast, monkeys require hundreds of sessions to ...

journal_title：Frontiers in neuroscience

authors： Muñoz-López M,Insausti R,Mohedano-Moriano A,Mishkin M,Saunders RC

更新日期：2015-05-18 00:00:00

abstract：:The autonomic nervous system (ANS) has a significant influence on the structural integrity and electrical conductivity of the atria. Aberrant activation of the sympathetic nervous system can induce heterogeneous changes with arrhythmogenic potential which can result in atrial tachycardia, atrial tachyarrhythmias and a...

journal_title：Frontiers in neuroscience

authors： Carnagarin R,Kiuchi MG,Ho JK,Matthews VB,Schlaich MP

更新日期：2019-01-23 00:00:00

abstract：Purpose:The study is conducted to identify the best corpus callosum (CC) sub-region that corresponds to highest callosal tissue alteration occurred due to Parkinsonism. In this regard the efficacy of local binary pattern (LBP) based texture analysis (TA) of CC is performed to quantify the changes in topographical distr...

journal_title：Frontiers in neuroscience

authors： Bhattacharya D,Sinha N,Prasad S,Pal PK,Saini J,Mangalore S

更新日期：2020-05-28 00:00:00

abstract：:Features and functions of long-range GABAergic projection neurons in the developing cerebral cortex have been reported previously, although until now their significance in the adult cerebral cortex has remained uncertain. The septo-hippocampal circuit is one exception - in this system, long-range mature GABAergic proj...

journal_title：Frontiers in neuroscience

authors： Tamamaki N,Tomioka R

更新日期：2010-12-08 00:00:00

abstract：:Anesthetized rodent models are ubiquitous in pre-clinical neuroimaging studies. However, because the associated cerebral morphology and experimental methodology results in a profound negative brain-core temperature differential, cerebral temperature changes during functional activation are likely to be principally dri...

journal_title：Frontiers in neuroscience

authors： Harris SS,Boorman LW,Das D,Kennerley AJ,Sharp PS,Martin C,Redgrave P,Schwartz TH,Berwick J

更新日期：2018-08-14 00:00:00

abstract：:Amputation of a sensory peripheral nerve induces severe anatomical and functional changes along the afferent pathway as well as perception alterations and neuropathic pain. In previous studies we showed that electrical stimulation applied to a transected infraorbital nerve protects the somatosensory cortex from the ab...

journal_title：Frontiers in neuroscience

authors： Virtuoso A,Herrera-Rincon C,Papa M,Panetsos F

更新日期：2019-05-01 00:00:00

abstract：:Homeostasis in the nervous system requires intricate regulation and is largely accomplished by the blood-brain barrier (BBB). The major gate keeper of the vertebrate BBB is vascular endothelial cells, which form tight junctions (TJs). To gain insight into the development of the BBB, we studied the carpet glia, a subpe...

journal_title：Frontiers in neuroscience

authors： Ho TY,Wu WH,Hung SJ,Liu T,Lee YM,Liu YH

更新日期：2019-03-29 00:00:00

abstract：:There is increasing evidence that metabolic dysfunction plays an important role in Alzheimer's disease (AD). Brain insulin resistance and subsequent impairment of insulin and insulin-like growth factor (IGF) signaling are associated with the neurodegenerative and clinical features of AD. Nevertheless, how the brain in...

journal_title：Frontiers in neuroscience

authors： Bonham LW,Geier EG,Steele NZR,Holland D,Miller BL,Dale AM,Desikan RS,Yokoyama JS,Alzheimer’s Disease Neuroimaging Initiative.

更新日期：2018-07-16 00:00:00

abstract：:The value of an object acquired by a particular action often determines the motivation to produce that action. Previous studies found neural signals related to the values of different objects or goods in the orbitofrontal cortex, while the values of outcomes expected from different actions are broadly represented in m...

journal_title：Frontiers in neuroscience

authors： Kim S,Cai X,Hwang J,Lee D

更新日期：2012-07-17 00:00:00

abstract：:Throughout the past decade, silicon-based neural probes have become a driving force in neural engineering. Such probes comprise sophisticated, integrated CMOS electronics which provide a large number of recording sites along slender probe shanks. Using such neural probes in a chronic setting often requires them to be ...

journal_title：Frontiers in neuroscience

authors： Chauvière L,Pothof F,Gansel KS,Klon-Lipok J,Aarts AAA,Holzhammer T,Paul O,Singer WJ,Ruther P

更新日期：2019-05-21 00:00:00

abstract：:In this work, we present a neuromorphic architecture for head pose estimation and scene representation for the humanoid iCub robot. The spiking neuronal network is fully realized in Intel's neuromorphic research chip, Loihi, and precisely integrates the issued motor commands to estimate the iCub's head pose in a neuro...

journal_title：Frontiers in neuroscience

authors： Kreiser R,Renner A,Leite VRC,Serhan B,Bartolozzi C,Glover A,Sandamirskaya Y

更新日期：2020-06-23 00:00:00

abstract：:Comorbid depressive disorders confound the diagnosis and therapy of schizophrenia. Using a murine model incorporating both MK801 and chronic unpredictable mild stress exposures, we successfully replicated both psychosis and depression. Ex vivo patch clamp recordings and in vivo calcium imaging demonstrated impaired ne...

journal_title：Frontiers in neuroscience

authors： Zhou C,Kong D,Xue R,Chen M,Li G,Xu Y,Liu S,Tian H,Zhuo C

更新日期：2020-06-03 00:00:00

abstract：:The increasing rate of age-related hearing loss (ARHL), with its subsequent reduction in quality of life and increase in health care costs, requires new therapeutic strategies to reduce and delay its impact. The goal of this study was to determine if ARHL could be reduced in a rat model by administering a combination ...

journal_title：Frontiers in neuroscience

authors： Alvarado JC,Fuentes-Santamaría V,Gabaldón-Ull MC,Juiz JM

更新日期：2018-07-31 00:00:00

abstract：:Gangliosides are glycosphingolipids highly abundant in the nervous system, and carry most of the sialic acid residues in the brain. Gangliosides are enriched in cell membrane microdomains ("lipid rafts") and play important roles in the modulation of membrane proteins and ion channels, in cell signaling and in the comm...

journal_title：Frontiers in neuroscience

authors： Sipione S,Monyror J,Galleguillos D,Steinberg N,Kadam V

更新日期：2020-10-06 00:00:00

abstract：BACKGROUND:With the advent of the GeneChip Exon Arrays, it is now possible to extract "exon-level" expression estimates, allowing for detection of alternative splicing events, one of the primary mechanisms of transcript diversity. In the context of (1) a complex trait use case and (2) a human cerebellum vs. heart compa...

journal_title：Frontiers in neuroscience

authors： Laderas TG,Walter NA,Mooney M,Vartanian K,Darakjian P,Buck K,Harrington CA,Belknap J,Hitzemann R,McWeeney SK

更新日期：2011-05-13 00:00:00

abstract：:Musicians have considerable experience naming pitch-classes with verbal (e.g., Doh, Ré, and Mi) and semiotic tags (e.g., musical notation). On the one end of the spectrum, musicians can identify the pitch of a piano tone or quality of a chord without a reference tone [i.e., absolute pitch (AP) or relative pitch], whic...

journal_title：Frontiers in neuroscience

authors： Sharma VV,Thaut M,Russo F,Alain C

更新日期：2019-09-06 00:00:00

abstract：:Inducing somatic cells into neural stem cells (iNSCs) in specific ways provides a new cell therapy in a variety of neurological diseases. In the past, iNSCs were generated by transcription factors which increased the risk of mutagenesis, tumor formations, and immune reactions by viral transduction vectors. Therefore, ...

journal_title：Frontiers in neuroscience

authors： Duan Q,Li S,Wen X,Sunnassee G,Chen J,Tan S,Guo Y

更新日期：2019-09-04 00:00:00

abstract：:Recent studies have shown that synaptic unreliability is a robust and sufficient mechanism for inducing the stochasticity observed in cortex. Here, we introduce Synaptic Sampling Machines (S2Ms), a class of neural network models that uses synaptic stochasticity as a means to Monte Carlo sampling and unsupervised learn...

journal_title：Frontiers in neuroscience

authors： Neftci EO,Pedroni BU,Joshi S,Al-Shedivat M,Cauwenberghs G

更新日期：2016-06-29 00:00:00

abstract：:Familiarity in music has been reported as an important factor modulating emotional and hedonic responses in the brain. Familiarity and repetition may increase the liking of a piece of music, thus inducing positive emotions. Neuroimaging studies have focused on identifying the brain regions involved in the processing o...

journal_title：Frontiers in neuroscience

authors： Freitas C,Manzato E,Burini A,Taylor MJ,Lerch JP,Anagnostou E

更新日期：2018-10-05 00:00:00

abstract：:Increasingly, neuroimaging researchers are exploring the use of real-time functional magnetic resonance imaging (rt-fMRI) as a way to access a participant's ongoing brain function throughout a scan. This approach presents novel and exciting experimental applications ranging from monitoring data quality in real time, t...

journal_title：Frontiers in neuroscience

authors： MacInnes JJ,Adcock RA,Stocco A,Prat CS,Rao RPN,Dickerson KC

更新日期：2020-09-15 00:00:00

abstract：:We investigated whether the categorical perception (CP) of speech might also provide a mechanism that aids its perception in noise. We varied signal-to-noise ratio (SNR) [clear, 0 dB, -5 dB] while listeners classified an acoustic-phonetic continuum (/u/ to /a/). Noise-related changes in behavioral categorization were ...

journal_title：Frontiers in neuroscience

authors： Bidelman GM,Bush LC,Boudreaux AM

更新日期：2020-02-27 00:00:00

abstract：:Analog arrays are a promising emerging hardware technology with the potential to drastically speed up deep learning. Their main advantage is that they employ analog circuitry to compute matrix-vector products in constant time, irrespective of the size of the matrix. However, ConvNets map very unfavorably onto analog a...

journal_title：Frontiers in neuroscience

authors： Rasch MJ,Gokmen T,Rigotti M,Haensch W

更新日期：2019-07-30 00:00:00

abstract：Background:Emerging evidence demonstrates that diet-induced obesity disrupts corticolimbic circuits underlying emotional regulation. Studies directed at understanding how obesity alters brain and behavior are easily confounded by a myriad of complications related to obesity. This study investigated the early neurobiolo...

journal_title：Frontiers in neuroscience

authors： Vega-Torres JD,Azadian M,Rios-Orsini RA,Reyes-Rivera AL,Ontiveros-Angel P,Figueroa JD

更新日期：2020-06-30 00:00:00

abstract：:We performed this study to investigate the possibility of a definitive pattern of Galectin-3 (Gal-3) expression in the cerebrospinal fluid (CSF) and serum of Alzheimer's disease (AD) and Amyotrophic Lateral Sclerosis (ALS) patients. In our study, we collected the CSF and serum samples of 31 AD patients, 19 ALS patient...

journal_title：Frontiers in neuroscience

authors： Ashraf GM,Baeesa SS

更新日期：2018-06-29 00:00:00

abstract：:Recent increases in attention deficit hyperactivity disorder (ADHD) diagnoses, and the escalation of stimulant prescriptions, has raised concern about diversion and abuse of stimulants, as well as the ethics of using these drugs as "cognitive enhancers."Such concern appears misplaced in the face of substantial evidenc...

journal_title：Frontiers in neuroscience

authors： Advokat C,Scheithauer M

更新日期：2013-05-29 00:00:00

abstract：:To ensure survival, animals must update the internal representations of their environment in a trial-and-error fashion. Psychological studies of associative learning and neurophysiological analyses of dopaminergic neurons have suggested that this updating process involves the temporal-difference (TD) method in the bas...

journal_title：Frontiers in neuroscience

authors： Wen C,Ogura Y,Matsushima T

更新日期：2016-11-08 00:00:00

abstract：:Although the genetic basis of Tourette Syndrome (TS) remains unclear, several candidate genes have been implicated. Using a set of 382 TS individuals of European ancestry we investigated four candidate genes for TS (HDC, SLITRK1, BTBD9, and SLC6A4) in an effort to identify possibly causal variants using a targeted re-...

journal_title：Frontiers in neuroscience

authors： Alexander J,Potamianou H,Xing J,Deng L,Karagiannidis I,Tsetsos F,Drineas P,Tarnok Z,Rizzo R,Wolanczyk T,Farkas L,Nagy P,Szymanska U,Androutsos C,Tsironi V,Koumoula A,Barta C,TSGeneSEE.,Sandor P,Barr CL,Tischfield

更新日期：2016-09-21 00:00:00

abstract：:Metabolic confusion has been linked to the pathogenesis of Parkinson's disease (PD), while the dynamic changes associated with the onset and progression of PD remain unclear. Herein, dynamic changes in metabolites were detected from the initiation to the development of 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPT...

journal_title：Frontiers in neuroscience

authors： Lu Y,Zhang X,Zhao L,Yang C,Pan L,Li C,Liu K,Bai G,Gao H,Yan Z

更新日期：2018-02-20 00:00:00

abstract：:A simple circuit for cost-benefit decision derived from behavioral and neural studies of the predatory sea-slug Pleurobranchaea may closely resemble that upon which the more complex valuation and decision processes of the social vertebrates are built. The neuronal natures of the pathways in the connectionist model com...

journal_title：Frontiers in neuroscience

authors： Hirayama K,Catanho M,Brown JW,Gillette R

更新日期：2012-08-31 00:00:00