Computational detection of alternative exon usage.

abstract：:We hypothesized that assessment of brain connectivity may shed light on the underpinnings of ocular hypertension (OHT), characterized by raised intraocular pressure (IOP) and no typical glaucomatous findings. OHT carries a risk for future glaucoma development, thus representing a model of presymptomatic condition. In ...

journal_title：Frontiers in neuroscience

authors： Giorgio A,Zhang J,Costantino F,De Stefano N,Frezzotti P

更新日期：2020-03-05 00:00:00

abstract：:Neurogenesis, the process of generating new neurons in the brain, fascinates researchers for its promise to affect multiple cognitive and functional processes in both health and disease. Many cellular pathways are involved in the regulation of neurogenesis, a complexity exemplified by the extensive regulation of this ...

journal_title：Frontiers in neuroscience

authors： Barak B,Feldman N,Okun E

更新日期：2014-08-28 00:00:00

abstract：:Rodent models have opened the door to a better understanding of the neurobiology of brain disorders and increased our ability to evaluate novel treatments. Resting-state functional magnetic resonance imaging (rs-fMRI) allows for in vivo exploration of large-scale brain networks with high spatial resolution. Its applic...

journal_title：Frontiers in neuroscience

authors： Bajic D,Craig MM,Mongerson CRL,Borsook D,Becerra L

更新日期：2017-12-12 00:00:00

abstract：:Recently, the putative association between selective serotonin reuptake inhibitor (SSRI) exposure during pregnancy and the development of social disorders in children has gained increased attention. However, clinical studies struggle with the confounding effects of maternal depression typically co-occurring with antid...

journal_title：Frontiers in neuroscience

authors： Houwing DJ,Staal L,Swart JM,Ramsteijn AS,Wöhr M,de Boer SF,Olivier JDA

更新日期：2019-03-12 00:00:00

abstract：:This paper reports on a benchmark dataset acquired with a brain-computer interface (BCI) system based on the rapid serial visual presentation (RSVP) paradigm. The dataset consists of 64-channel electroencephalogram (EEG) data from 64 healthy subjects (sub1,…, sub64) while they performed a target image detection task. ...

journal_title：Frontiers in neuroscience

authors： Zhang S,Wang Y,Zhang L,Gao X

更新日期：2020-10-02 00:00:00

abstract：:Alzheimer disease (AD) and vascular dementia (VaD) together represent the majority of dementia cases. Since their neuropsychological profiles often overlap and white matter lesions are observed in elderly subjects including AD, differentiating between VaD and AD can be difficult. Characterization of these different fo...

journal_title：Frontiers in neuroscience

authors： Palesi F,De Rinaldis A,Vitali P,Castellazzi G,Casiraghi L,Germani G,Bernini S,Anzalone N,Ramusino MC,Denaro FM,Sinforiani E,Costa A,Magenes G,D'Angelo E,Gandini Wheeler-Kingshott CAM,Micieli G

更新日期：2018-04-25 00:00:00

abstract：:In functional MRI (fMRI), population receptive field (pRF) models allow a quantitative description of the response as a function of the features of the stimuli that are relevant for each voxel. The most popular pRF model used in fMRI assumes a Gaussian shape in the features space (e.g., the visual field) reducing the ...

journal_title：Frontiers in neuroscience

authors： Lage-Castellanos A,Valente G,Senden M,De Martino F

更新日期：2020-07-30 00:00:00

abstract：:The enteric glia, a neural crest-derived cell type that composes the Enteric Nervous System, is involved in controlling gut functions, including motility, gut permeability, and neuronal communication. Moreover this glial cell could to give rise to new neurons. It is believed that enteric neurons are generated up to 21...

journal_title：Frontiers in neuroscience

authors： Veríssimo CP,Carvalho JDS,da Silva FJM,Campanati L,Moura-Neto V,Coelho-Aguiar JM

更新日期：2019-09-03 00:00:00

abstract：:Some studies identified hypo-connectivity, while others showed hyper-connectivity of the insula in the autism spectrum disorders (ASD). These contradictory findings leave open the question of whether and to what extent functional connectivity of the insula is altered and how functional connectivity of the insula is as...

journal_title：Frontiers in neuroscience

authors： Xu J,Wang H,Zhang L,Xu Z,Li T,Zhou Z,Zhou Z,Gan Y,Hu Q

更新日期：2018-04-11 00:00:00

abstract：:Cognitive changes after menopause are a common complaint, especially as the loss of estradiol at menopause has been hypothesized to contribute to the higher rates of dementia in women. To explore the neural processes related to subjective cognitive complaints, this study examined resting state functional connectivity ...

journal_title：Frontiers in neuroscience

authors： Vega JN,Zurkovsky L,Albert K,Melo A,Boyd B,Dumas J,Woodward N,McDonald BC,Saykin AJ,Park JH,Naylor M,Newhouse PA

更新日期：2016-09-23 00:00:00

abstract：:Posttraumatic stress disorder (PTSD) is an anxiety disorder characterized by intrusive recollections of a severe traumatic event and hyperarousal following exposure to the event. Human and animal studies have shown that the change of amygdala activity after traumatic stress may contribute to occurrences of some sympto...

journal_title：Frontiers in neuroscience

authors： Fang Q,Li Z,Huang GD,Zhang HH,Chen YY,Zhang LB,Ding ZB,Shi J,Lu L,Yang JL

更新日期：2018-08-21 00:00:00

abstract：:Autism spectrum disorders (ASD) are pervasive neurodevelopmental disorders entailing social and cognitive deficits, including marked problems with language. Numerous genes have been associated with ASD, but it is unclear how language deficits arise from gene mutation or dysregulation. It is also unclear why ASD shows ...

journal_title：Frontiers in neuroscience

authors： Benítez-Burraco A,Lattanzi W,Murphy E

更新日期：2016-08-29 00:00:00

abstract：:Sensory information can interact to impact perception and behavior. Foods are appreciated according to their appearance, smell, taste and texture. Athletes and dancers combine visual, auditory, and somatosensory information to coordinate their movements. Under laboratory settings, detection and discrimination are like...

journal_title：Frontiers in neuroscience

authors： Sperdin HF,Cappe C,Murray MM

更新日期：2010-05-15 00:00:00

abstract：:Event-driven neuromorphic spiking sensors such as the silicon retina and the silicon cochlea encode the external sensory stimuli as asynchronous streams of spikes across different channels or pixels. Combining state-of-art deep neural networks with the asynchronous outputs of these sensors has produced encouraging res...

journal_title：Frontiers in neuroscience

authors： Anumula J,Neil D,Delbruck T,Liu SC

更新日期：2018-02-09 00:00:00

abstract：:In functional magnetic resonance imaging (fMRI), functional connectivity is conventionally characterized by correlations between fMRI time series, which are intrinsically undirected measures of connectivity. Yet, some information about the directionality of network connections can nevertheless be extracted from the ma...

journal_title：Frontiers in neuroscience

authors： Lennartz C,Schiefer J,Rotter S,Hennig J,LeVan P

更新日期：2018-05-08 00:00:00

abstract：:In our complex acoustic environment, we are confronted with a mixture of sounds produced by several simultaneous sources. However, we rarely perceive these sounds as incomprehensible noise. Our brain uses perceptual organization processes to independently follow the emission of each sound source over time. If the acou...

journal_title：Frontiers in neuroscience

authors： Bidet-Caulet A,Bertrand O

更新日期：2009-09-15 00:00:00

abstract：:Funding institutions and researchers increasingly expect that data will be shared to increase scientific integrity and provide other scientists with the opportunity to use the data with novel methods that may advance understanding in a particular field of study. In practice, sharing human subject data can be complicat...

journal_title：Frontiers in neuroscience

authors： Song X,Wang J,Wang A,Meng Q,Prescott C,Tsu L,Eckert MA

更新日期：2015-09-22 00:00:00

abstract：:Bispectral analysis is a signal processing technique that makes it possible to capture the non-linear and non-Gaussian properties of the EEG signals. It has found various applications in EEG research and clinical practice, including the assessment of anesthetic depth, the identification of epileptic seizures, and more...

journal_title：Frontiers in neuroscience

authors： Chella F,D'Andrea A,Basti A,Pizzella V,Marzetti L

更新日期：2017-05-16 00:00:00

abstract：:Huntington Disease (HD) is a genetic neurodegenerative disorder characterized by broad types of cellular and molecular dysfunctions that may affect both neuronal and non-neuronal cell populations. Among all the molecular mechanisms underlying the complex pathogenesis of the disease, alteration of sphingolipids has bee...

journal_title：Frontiers in neuroscience

authors： Di Pardo A,Amico E,Maglione V

更新日期：2016-10-06 00:00:00

abstract：Introduction:Optical coherence tomography angiography (OCT-A) is a novel diagnostic tool with increasing applications in ophthalmology clinics that provides non-invasive high-resolution imaging of the retinal microvasculature. Our aim is to report in detail an experimental protocol for analyzing both vasodilatory and v...

journal_title：Frontiers in neuroscience

authors： Sousa DC,Leal I,Moreira S,do Vale S,Silva-Herdade AS,Aguiar P,Dionísio P,Abegão Pinto L,Castanho MARB,Marques-Neves C

更新日期：2019-06-12 00:00:00

abstract：:The neurohormone oxytocin (OXT) has been found to mediate the regulation of complex socioemotional cognition in multiple ways both in humans and other animals. Recent studies have investigated the effects of OXT in different levels of analysis (from genetic to behavioral) chiefly targeting its impact on the social com...

journal_title：Frontiers in neuroscience

authors： Theofanopoulou C

更新日期：2016-06-14 00:00:00

abstract：:In healthy older adults, resveratrol supplementation has been shown to improve long-term glucose control, resting-state functional connectivity (RSFC) of the hippocampus, and memory function. Here, we aimed to investigate if these beneficial effects extend to individuals at high-risk for dementia, i.e., patients with ...

journal_title：Frontiers in neuroscience

authors： Köbe T,Witte AV,Schnelle A,Tesky VA,Pantel J,Schuchardt JP,Hahn A,Bohlken J,Grittner U,Flöel A

更新日期：2017-03-07 00:00:00

abstract：:Aging is a complex natural phenomenon that is manifested by degenerative changes in the structure and function of cells and tissues. D-Galactose-induced aging mice are an artificial accelerated aging model that causes memory and learning impairment, oxidative stress, and neuroinflammation. In this study, we examined t...

journal_title：Frontiers in neuroscience

authors： Li H,Zheng L,Chen C,Liu X,Zhang W

更新日期：2019-09-18 00:00:00

abstract：:Glutamate-induced excitotoxicity is one of the main causes of neuronal cell death in stroke. Compound 22a has been previously reported as a promising neuroprotective compound derived from tetramethylpyrazine, which is a widely used active ingredient of traditional Chinese medicine Chuanxiong (Ligusticum wallichii Fran...

journal_title：Frontiers in neuroscience

authors： Chen H,Cao J,Zhu Z,Zhang G,Shan L,Yu P,Wang Y,Sun Y,Zhang Z

更新日期：2018-08-15 00:00:00

abstract：:Anesthetized rodent models are ubiquitous in pre-clinical neuroimaging studies. However, because the associated cerebral morphology and experimental methodology results in a profound negative brain-core temperature differential, cerebral temperature changes during functional activation are likely to be principally dri...

journal_title：Frontiers in neuroscience

authors： Harris SS,Boorman LW,Das D,Kennerley AJ,Sharp PS,Martin C,Redgrave P,Schwartz TH,Berwick J

更新日期：2018-08-14 00:00:00

abstract：:Intracranial chemical injection (ICI) methods have been used to identify the locations in the brain where feeding behavior can be controlled acutely. Scientists conducting ICI studies often document their injection site locations, thereby leaving kernels of valuable location data for others to use to further character...

journal_title：Frontiers in neuroscience

authors： Khan AM

更新日期：2013-12-18 00:00:00

abstract：:Overview: We model energy constraints in a network of spiking neurons, while exploring general questions of resource limitation on network function abstractly. Background: Metabolic states like dietary ketosis or hypoglycemia have a large impact on brain function and disease outcomes. Glia provide metabolic support fo...

journal_title：Frontiers in neuroscience

authors： Burroni J,Taylor P,Corey C,Vachnadze T,Siegelmann HT

更新日期：2017-02-27 00:00:00

abstract：:[This corrects the article DOI: 10.3389/fnins.2019.00413.]. ...

journal_title：Frontiers in neuroscience

authors： Frontiers Production Office.

更新日期：2019-08-28 00:00:00

abstract：:An associative brain-computer-interface (BCI) that correlates in time a peripherally generated afferent volley with the peak negativity (PN) of the movement related cortical potential (MRCP) induces plastic changes in the human motor cortex. However, in this associative BCI the movement timed to a cue is not detected ...

journal_title：Frontiers in neuroscience

authors： Mrachacz-Kersting N,Aliakbaryhosseinabadi S

更新日期：2018-07-11 00:00:00

abstract：:This paper presents a real-time, low-complexity neuromorphic speech recognition system using a spiking silicon cochlea, a feature extraction module and a population encoding method based Neural Engineering Framework (NEF)/Extreme Learning Machine (ELM) classifier IC. Several feature extraction methods with varying mem...

journal_title：Frontiers in neuroscience

authors： Acharya J,Patil A,Li X,Chen Y,Liu SC,Basu A

更新日期：2018-03-28 00:00:00