Language Impairments in ASD Resulting from a Failed Domestication of the Human Brain.

abstract：Background:Cranial irradiation is a common therapy for the treatment of brain tumors, but unfortunately patients suffer from side effects, particularly cognitive impairment, caused by neurodegenerative and neuroinflammatory mechanisms. Finding a therapeutic agent protecting hippocampal neurons would be beneficial. Fing...

journal_title：Frontiers in neuroscience

authors： Metzdorf J,Hobloss Z,Schlevogt S,Ayzenberg I,Stahlke S,Pedreiturria X,Haupeltshofer S,Gold R,Tönges L,Kleiter I

更新日期：2019-07-09 00:00:00

abstract：:Although the major causative factors of Alzheimer's disease (AD) are the accumulation of amyloid β and hyperphosphorylated tau, AD can also be caused by metabolic dysfunction. The major clinical symptom of AD is cognitive dysfunction. However, AD is also accompanied by various secondary symptoms such as depression, sl...

journal_title：Frontiers in neuroscience

authors： Kim S,Nam Y,Shin SJ,Park YH,Jeon SG,Kim JI,Kim MJ,Moon M

更新日期：2020-09-24 00:00:00

abstract：:Cochlear outer hair cells (OHC) receive direct efferent feedback from the caudal auditory brainstem via the medial olivocochlear (MOC) bundle. This circuit provides the neural substrate for the MOC reflex, which inhibits cochlear amplifier gain and is believed to play a role in listening in noise and protection from a...

journal_title：Frontiers in neuroscience

authors： Smith SB,Lichtenhan JT,Cone BK

更新日期：2017-04-04 00:00:00

abstract：:Chronic exposure to alcohol produces adaptations within the basolateral amygdala (BLA) that are associated with the development of anxiety-like behaviors during withdrawal. In part, these adaptations are mediated by plasticity in glutamatergic synapses occurring through an AMPA receptor mediated form of post-synaptic ...

journal_title：Frontiers in neuroscience

authors： Gioia DA,Alexander N,McCool BA

更新日期：2017-07-21 00:00:00

abstract：:Aggressive behavior is associated with dysfunctional frontolimbic emotion regulation circuits. Recent findings suggest serotonin as a primary transmitter for prefrontal amygdala control. However, the association between serotonin levels, amygdala regulation, and aggression is still a matter of debate. Neurobehavioral ...

journal_title：Frontiers in neuroscience

authors： Klasen M,Wolf D,Eisner PD,Eggermann T,Zerres K,Zepf FD,Weber R,Mathiak K

更新日期：2019-02-22 00:00:00

abstract：:Antipsychotic drugs (APDs) are widely prescribed to control various mental disorders. As mental disorders are chronic diseases, these drugs are often used over a life-time. However, APDs can cause serious glucometabolic side-effects including type 2 diabetes and hyperglycaemic emergency, leading to medication non-comp...

journal_title：Frontiers in neuroscience

authors： Chen J,Huang XF,Shao R,Chen C,Deng C

更新日期：2017-11-21 00:00:00

abstract：:Brain functional connectivity network (BFCN) analysis has been widely used in the diagnosis of mental disorders, such as schizophrenia. In BFCN methods, brain network construction is one of the core tasks due to its great influence on the diagnosis result. Most of the existing BFCN construction methods only consider t...

journal_title：Frontiers in neuroscience

authors： Zhu Q,Li H,Huang J,Xu X,Guan D,Zhang D

更新日期：2019-06-14 00:00:00

abstract：:Beside diverse therapeutic properties of palmitoylethanolamide (PEA) including: neuroprotection, inflammation and pain alleviation, prophylactic effects have also been reported in animal models of infections, inflammation, and neurological diseases. The availability of PEA as (ultra)micronized nutraceutical formulatio...

journal_title：Frontiers in neuroscience

authors： Lerner R,Pascual Cuadrado D,Post JM,Lutz B,Bindila L

更新日期：2019-06-11 00:00:00

abstract：:Neural oscillations in the alpha band (7-13 Hz) are commonly associated with disengagement of visual attention. However, recent studies have also associated alpha with processes of attentional control and stability. We addressed this issue in previous experiments by delivering transcranial alternating current stimulat...

journal_title：Frontiers in neuroscience

authors： Clayton MS,Yeung N,Cohen Kadosh R

更新日期：2018-02-13 00:00:00

abstract：:In this paper, we introduce a novel automatic method for Corpus Callosum (CC) in midsagittal plane segmentation. The robust segmentation of CC in midsagittal plane is key role for quantitative study of structural features of CC associated with various neurological disorder such as epilepsy, autism, Alzheimer's disease...

journal_title：Frontiers in neuroscience

authors： Park G,Kwak K,Seo SW,Lee JM

更新日期：2018-09-11 00:00:00

abstract：:Induction of lordosis as typical female sexual behavior in rodents is dependent on a mount stimulus from males and blood levels of estrogen. Periaqueductal gray (PAG) efferent neurons have been suggested to be important for lordosis behavior; however, the neurochemical basis remains to be understood. In this study, we...

journal_title：Frontiers in neuroscience

authors： Yamada S,Kawata M

更新日期：2014-12-18 00:00:00

abstract：:The combination of electromyography (EMG) and transcranial magnetic stimulation (TMS) offers a powerful non-invasive approach for investigating corticospinal excitability in both humans and animals. Acquiring and analyzing the data produced with this combination of tools requires overcoming multiple technical hurdles....

journal_title：Frontiers in neuroscience

authors： Jackson N,Greenhouse I

更新日期：2019-09-13 00:00:00

abstract：:Encouraged by a rise of reciprocal interest between the machine learning and neuroscience communities, several recent studies have demonstrated the explanatory power of statistical learning techniques for the analysis of neural data. In order to facilitate a wider adoption of these methods, neuroscientific research ne...

journal_title：Frontiers in neuroscience

authors： Hanke M,Halchenko YO,Haxby JV,Pollmann S

更新日期：2010-05-15 00:00:00

abstract：:The increasing rate of age-related hearing loss (ARHL), with its subsequent reduction in quality of life and increase in health care costs, requires new therapeutic strategies to reduce and delay its impact. The goal of this study was to determine if ARHL could be reduced in a rat model by administering a combination ...

journal_title：Frontiers in neuroscience

authors： Alvarado JC,Fuentes-Santamaría V,Gabaldón-Ull MC,Juiz JM

更新日期：2018-07-31 00:00:00

abstract：:Numerous observational studies have shown that depressive symptoms are common in individuals with mild cognitive impairment (MCI) who have a higher rate of progress to dementia. However, it is still uncertain whether there are any differences between MCI patients with and without depression symptom in their brain func...

journal_title：Frontiers in neuroscience

authors： Yu Y,Li Z,Lin Y,Yu J,Peng G,Zhang K,Jia X,Luo B

更新日期：2019-12-17 00:00:00

abstract：:The Iowa Gambling Task (IGT) has been widely used to assess differences in decision-making under uncertainty. Recently, several studies have shown that healthy subjects do not meet the basic predictions of the task (i.e., prefer options with positive long-term outcome), hence questioning its basic assumptions. Since c...

journal_title：Frontiers in neuroscience

authors： Horstmann A,Villringer A,Neumann J

更新日期：2012-05-14 00:00:00

abstract：:L-DOPA-induced dyskinesia (LID) represents one of the major problems of the long-term therapy of patients with Parkinson's disease (PD). Although, the pathophysiologic mechanisms underlying LID are not completely understood, activation of the extracellular signal regulated kinase (ERK) is recognized to play a key role...

journal_title：Frontiers in neuroscience

authors： Chen G,Nie S,Han C,Ma K,Xu Y,Zhang Z,Papa SM,Cao X

更新日期：2017-03-09 00:00:00

abstract：:Alzheimer disease (AD) and vascular dementia (VaD) together represent the majority of dementia cases. Since their neuropsychological profiles often overlap and white matter lesions are observed in elderly subjects including AD, differentiating between VaD and AD can be difficult. Characterization of these different fo...

journal_title：Frontiers in neuroscience

authors： Palesi F,De Rinaldis A,Vitali P,Castellazzi G,Casiraghi L,Germani G,Bernini S,Anzalone N,Ramusino MC,Denaro FM,Sinforiani E,Costa A,Magenes G,D'Angelo E,Gandini Wheeler-Kingshott CAM,Micieli G

更新日期：2018-04-25 00:00:00

abstract：:Depression is a highly heterogeneous disease characterized by symptoms spanning from anhedonia and behavioral despair to social withdrawal and learning deficit. Such diversity of behavioral phenotypes suggests that discrete neural circuits may underlie precise aspects of the disease, rendering its treatment an unmet c...

journal_title：Frontiers in neuroscience

authors： Nuno-Perez A,Tchenio A,Mameli M,Lecca S

更新日期：2018-07-23 00:00:00

abstract：:Background: Tourette Syndrome (TS) is a neurodevelopmental disorder with childhood-onset, with a typical decline in tic severity, as well as an increasing ability to suppress tics in late childhood and adolescence. These processes develop in parallel with general improvement of self-regulatory abilities, and performan...

journal_title：Frontiers in neuroscience

authors： Eichele H,Eichele T,Marquardt L,Adolfsdottir S,Hugdahl K,Sørensen L,Plessen KJ

更新日期：2017-06-12 00:00:00

abstract：:We performed this study to investigate the possibility of a definitive pattern of Galectin-3 (Gal-3) expression in the cerebrospinal fluid (CSF) and serum of Alzheimer's disease (AD) and Amyotrophic Lateral Sclerosis (ALS) patients. In our study, we collected the CSF and serum samples of 31 AD patients, 19 ALS patient...

journal_title：Frontiers in neuroscience

authors： Ashraf GM,Baeesa SS

更新日期：2018-06-29 00:00:00

abstract：:Spatial group independent component analysis (GICA) methods decompose multiple-subject functional magnetic resonance imaging (fMRI) data into a linear mixture of spatially independent components (ICs), some of which are subsequently characterized as brain functional networks. Group information guided independent compo...

journal_title：Frontiers in neuroscience

authors： Du Y,Lin D,Yu Q,Sui J,Chen J,Rachakonda S,Adali T,Calhoun VD

更新日期：2017-05-19 00:00:00

abstract：:The feedback-related negativity (FRN) is a mid-frontal event-related potential (ERP) recorded in various cognitive tasks and associated with the onset of sensory feedback signaling decision outcome. Some properties of the FRN are still debated, notably its sensitivity to positive and negative reward prediction error (...

journal_title：Frontiers in neuroscience

authors： Sallet J,Camille N,Procyk E

更新日期：2013-11-14 00:00:00

abstract：Purpose:To evaluate the effect of resolution on iron content using quantitative susceptibility mapping (QSM); to verify the consistency of QSM across field strengths and manufacturers in evaluating the iron content of deep gray matter (DGM) of the human brain using subjects from multiple sites; and to establish a susce...

journal_title：Frontiers in neuroscience

authors： Li Y,Sethi SK,Zhang C,Miao Y,Yerramsetty KK,Palutla VK,Gharabaghi S,Wang C,He N,Cheng J,Yan F,Haacke EM

更新日期：2021-01-06 00:00:00

abstract：:Several neural decoding algorithms have successfully converted brain signals into commands to control a computer cursor and prosthetic devices. A majority of decoding methods, such as population vector algorithms (PVA), optimal linear estimators (OLE), and neural networks (NN), are effective in predicting movement kin...

journal_title：Frontiers in neuroscience

authors： Yang SH,Chen YY,Lin SH,Liao LD,Lu HH,Wang CF,Chen PC,Lo YC,Phan TD,Chao HY,Lin HC,Lai HY,Huang WC

更新日期：2016-12-09 00:00:00

abstract：:Exposure in vivo (EXP) is a cognitive-behavioral treatment aimed at reducing pain-related fear in chronic pain, and has proven successful in reducing pain-related disability in patients with chronic low back pain (cLBP). The current longitudinal study aimed to reveal the neural correlates of changes in pain-related fe...

journal_title：Frontiers in neuroscience

authors： Timmers I,de Jong JR,Goossens M,Verbunt JA,Smeets RJ,Kaas AL

更新日期：2019-09-17 00:00:00

abstract：:Advanced algorithms are required to reveal the complex relations between neural and behavioral data. In this study, forelimb electromyography (EMG) signals were reconstructed from multi-unit neural signals recorded with multiple electrode arrays (MEAs) from the corticospinal tract (CST) in rats. A six-layer convolutio...

journal_title：Frontiers in neuroscience

authors： Guo Y,Gok S,Sahin M

更新日期：2018-10-17 00:00:00

abstract：:The blood-brain barrier (BBB) mediates the communication between the periphery and the central nervous system (CNS). Recently, CNS insulin resistance has been elucidated to play a role in neurodegenerative disease. This has stimulated a wealth of information on the molecular impact of insulin in the brain, particularl...

journal_title：Frontiers in neuroscience

authors： Rhea EM,Banks WA

更新日期：2019-06-04 00:00:00

abstract：:Brain-derived neurotrophic factor (BDNF) is a potent regulator of neuronal development and synaptic plasticity that is fundamental to neural circuit formation and cognition. It is also involved in the control of appetite and body weight, with mutations in the genes for BDNF and its receptor, TrkB, resulting in remarka...

journal_title：Frontiers in neuroscience

authors： Vanevski F,Xu B

更新日期：2013-03-21 00:00:00

abstract：:The neurodegenerative disorder multiple system atrophy (MSA) is characterized by autonomic failure, cerebellar ataxia and parkinsonism in any combination associated with predominantly oligodendroglial α-synuclein (α-syn) aggregates (glial cytoplasmic inclusions = GCIs). To date, there is no effective disease modifying...

journal_title：Frontiers in neuroscience

authors： Fellner L,Kuzdas-Wood D,Levin J,Ryazanov S,Leonov A,Griesinger C,Giese A,Wenning GK,Stefanova N

更新日期：2016-03-10 00:00:00