The behavioral relevance of multisensory neural response interactions.

abstract：:Speech perception under audiovisual (AV) conditions is well known to confer benefits to perception such as increased speed and accuracy. Here, we investigated how AV training might benefit or impede auditory perceptual learning of speech degraded by vocoding. In Experiments 1 and 3, participants learned paired associa...

journal_title：Frontiers in neuroscience

authors： Bernstein LE,Auer ET Jr,Eberhardt SP,Jiang J

更新日期：2013-03-18 00:00:00

abstract：:Gangliosides are glycosphingolipids highly abundant in the nervous system, and carry most of the sialic acid residues in the brain. Gangliosides are enriched in cell membrane microdomains ("lipid rafts") and play important roles in the modulation of membrane proteins and ion channels, in cell signaling and in the comm...

journal_title：Frontiers in neuroscience

authors： Sipione S,Monyror J,Galleguillos D,Steinberg N,Kadam V

更新日期：2020-10-06 00:00:00

abstract：:Manual scoring of polysomnography data is labor-intensive and time-consuming, and most existing software does not account for subjective differences and user variability. Therefore, we evaluated a supervised machine learning algorithm, SomnivoreTM, for automated wake-sleep stage classification. We designed an algorith...

journal_title：Frontiers in neuroscience

authors： Allocca G,Ma S,Martelli D,Cerri M,Del Vecchio F,Bastianini S,Zoccoli G,Amici R,Morairty SR,Aulsebrook AE,Blackburn S,Lesku JA,Rattenborg NC,Vyssotski AL,Wams E,Porcheret K,Wulff K,Foster R,Chan JKM,Nicholas CL,Fre

更新日期：2019-03-18 00:00:00

abstract：:This work presents sPyNNaker 4.0.0, the latest version of the software package for simulating PyNN-defined spiking neural networks (SNNs) on the SpiNNaker neuromorphic platform. Operations underpinning realtime SNN execution are presented, including an event-based operating system facilitating efficient time-driven ne...

journal_title：Frontiers in neuroscience

authors： Rhodes O,Bogdan PA,Brenninkmeijer C,Davidson S,Fellows D,Gait A,Lester DR,Mikaitis M,Plana LA,Rowley AGD,Stokes AB,Furber SB

更新日期：2018-11-20 00:00:00

abstract：:The characterization of the functional network of the brain dynamics has become a prominent tool to illuminate novel aspects of brain functioning. Due to its excellent time resolution, such research is oftentimes based on electroencephalographic recordings (EEG). However, a particular EEG-reference might cause crucial...

journal_title：Frontiers in neuroscience

authors： Ríos-Herrera WA,Olguín-Rodríguez PV,Arzate-Mena JD,Corsi-Cabrera M,Escalona J,Marín-García A,Ramos-Loyo J,Rivera AL,Rivera-López D,Zapata-Berruecos JF,Müller MF

更新日期：2019-09-12 00:00:00

abstract：Background:A number of mental illness is often re-diagnosed to be bipolar disorder (BD). Furthermore, the prefronto-limbic-striatal regions seem to be associated with the main dysconnectivity of BD. Functional connectivity is potentially an appropriate objective neurobiological marker that can assist with BD diagnosis....

journal_title：Frontiers in neuroscience

authors： Chen YL,Tu PC,Huang TH,Bai YM,Su TP,Chen MH,Wu YT

更新日期：2020-10-20 00:00:00

abstract：Introduction:Optical coherence tomography angiography (OCT-A) is a novel diagnostic tool with increasing applications in ophthalmology clinics that provides non-invasive high-resolution imaging of the retinal microvasculature. Our aim is to report in detail an experimental protocol for analyzing both vasodilatory and v...

journal_title：Frontiers in neuroscience

authors： Sousa DC,Leal I,Moreira S,do Vale S,Silva-Herdade AS,Aguiar P,Dionísio P,Abegão Pinto L,Castanho MARB,Marques-Neves C

更新日期：2019-06-12 00:00:00

abstract：:The diterpenoid compound, Oridonin, extracted from the Chinese herb, Rabdosia rubescens, possesses multiple biological activities and properties. Oridonin exhibited efficient anti-inflammatory activity by inducing a switch in macrophage polarization to the anti-inflammatory phenotype through inhibition of the Notch pa...

journal_title：Frontiers in neuroscience

authors： Xu L,Li L,Zhang CY,Schluesener H,Zhang ZY

更新日期：2019-04-02 00:00:00

abstract：:Neuromorphic computing employs models of neuronal circuits to solve computing problems. Neuromorphic hardware systems are now becoming more widely available and "neuromorphic algorithms" are being developed. As they are maturing toward deployment in general research environments, it becomes important to assess and com...

journal_title：Frontiers in neuroscience

authors： Diamond A,Nowotny T,Schmuker M

更新日期：2016-01-08 00:00:00

abstract：:Pain and stress are both phenomena that challenge an individual's homeostasis and have significant overlap in conceptual and physiological processes. Allostasis is the ability to adapt to pain and stress and maintain homeostasis; however, if either process becomes chronic, it may result in negative long-term outcomes....

journal_title：Frontiers in neuroscience

authors： Lunde CE,Sieberg CB

更新日期：2020-03-26 00:00:00

abstract：:The ability to precisely monitor and manipulate neural circuits is essential to understand the brain. Advancements over the last decade in optical techniques such as calcium imaging and optogenetics have empowered researchers to gain insight into brain function by systematically manipulating or monitoring defined neur...

journal_title：Frontiers in neuroscience

authors： Stamatakis AM,Schachter MJ,Gulati S,Zitelli KT,Malanowski S,Tajik A,Fritz C,Trulson M,Otte SL

更新日期：2018-07-24 00:00:00

abstract：:Neurodegenerative diseases are a challenge for drug discovery, as the biological mechanisms are complex and poorly understood, with a paucity of models that faithfully recapitulate these disorders. Recent advances in stem cell technology have provided a paradigm shift, providing researchers with tools to generate huma...

journal_title：Frontiers in neuroscience

authors： Han C,Chaineau M,Chen CX,Beitel LK,Durcan TM

更新日期：2018-02-06 00:00:00

abstract：:The cerebellum is one of the most consistent sites of abnormality in autism spectrum disorder (ASD) and cerebellar damage is associated with an increased risk of ASD symptoms, suggesting that cerebellar dysfunction may play a crucial role in the etiology of ASD. The cerebellum forms multiple closed-loop circuits with ...

journal_title：Frontiers in neuroscience

authors： D'Mello AM,Stoodley CJ

更新日期：2015-11-05 00:00:00

abstract：:The R47H coding variant of the triggering receptor expressed on myeloid cells-2 (TREM2) increases the risk of Alzheimer's disease (AD) similar to apolipoprotein E4. TREM2 R47H has recently been shown to have impaired binding to damage-associated lipid or apolipoprotein ligands. However, it is not known how this R47H v...

journal_title：Frontiers in neuroscience

authors： Park JS,Ji IJ,Kim DH,An HJ,Yoon SY

更新日期：2017-01-18 00:00:00

abstract：:Introduction: Changes in the autonomic nervous system due to Obstructive Sleep Apnea (OSA) during the life span have been described. Some pediatric studies have shown cardiovascular effects in children who do not fit the criteria for OSA; namely children with mild sleep disordered breathing. Objective: We investigated...

journal_title：Frontiers in neuroscience

authors： Lopes MC,Spruyt K,Azevedo-Soster L,Rosa A,Guilleminault C

更新日期：2019-01-10 00:00:00

abstract：:Silver nano-particles (Ag-NPs) are becoming increasingly prevalent in consumer products as antibacterial agents. The increased use of Ag NP-enhanced products will almost certainly increase environmental silver levels, resulting in increased exposures and the potential for increased adverse reactions including neurotox...

journal_title：Frontiers in neuroscience

authors： Liu F,Mahmood M,Xu Y,Watanabe F,Biris AS,Hansen DK,Inselman A,Casciano D,Patterson TA,Paule MG,Slikker W Jr,Wang C

更新日期：2015-04-08 00:00:00

abstract：:Increasing evidence suggests that noncoding RNAs play key roles in cellular processes, particularly in the brain. The present study used RNA sequencing to identify the transcriptional landscape of two human neural progenitor cell lines, SK-N-SH and ReNcell CX, as they differentiate into human cortical projection neuro...

journal_title：Frontiers in neuroscience

authors： Hecht PM,Ballesteros-Yanez I,Grepo N,Knowles JA,Campbell DB

更新日期：2015-10-23 00:00:00

abstract：:After been exposed to the visual input, in the first year of life, the brain experiences subtle but massive changes apparently crucial for communicative/emotional and social human development. Its lack could be the explanation of the very high prevalence of autism in children with total congenital blindness. The prese...

journal_title：Frontiers in neuroscience

authors： Jure R

更新日期：2019-01-09 00:00:00

abstract：:Circadian rhythms of behavior and physiology are generated by central and peripheral circadian oscillators entrained by periodic environmental or physiological stimuli. A master circadian pacemaker in the hypothalamic suprachiasmatic nucleus (SCN) is directly entrained by daily light-dark (LD) cycles, and coordinates ...

journal_title：Frontiers in neuroscience

authors： Patton DF,Mistlberger RE

更新日期：2013-10-14 00:00:00

abstract：:This paper developed a cognitive task-load (CTL) classification algorithm and allocation strategy to sustain the optimal operator CTL levels over time in safety-critical human-machine integrated systems. An adaptive human-machine system is designed based on a non-linear dynamic CTL classifier, which maps a set of elec...

journal_title：Frontiers in neuroscience

authors： Zhang J,Yin Z,Wang R

更新日期：2017-03-17 00:00:00

abstract：:The dynamical systems view of movement generation in motor cortical areas has emerged as an effective way to explain the firing properties of populations of neurons recorded from these regions. Recently, many studies have focused on finding low-dimensional representations of these dynamical systems during voluntary re...

journal_title：Frontiers in neuroscience

authors： Xing D,Aghagolzadeh M,Truccolo W,Borton D

更新日期：2019-10-04 00:00:00

abstract：:Poisoning with organophosphorus compounds (OPCs) is a major problem worldwide. Standard therapy with atropine and established oxime-type enzyme reactivators (pralidoxime, obidoxime) is unsatisfactory. In search of more efficacious broad-spectrum oximes, new bispyridinium (K-) oximes have been synthesized, with K027 be...

journal_title：Frontiers in neuroscience

authors： Lorke DE,Petroianu GA

更新日期：2019-05-22 00:00:00

abstract：:Progranulin (PGRN) is a tightly regulated, secreted glycoprotein involved in a wide range of biological processes that is of tremendous interest to the scientific community due to its involvement in neoplastic, neurodevelopmental, and neurodegenerative diseases. In particular, progranulin haploinsufficiency leads to f...

journal_title：Frontiers in neuroscience

authors： Gururaj S,Sampognaro PJ,Argouarch AR,Kao AW

更新日期：2020-12-14 00:00:00

abstract：:Concerns regarding a drought in psychopharmacology have risen from many quarters. From one perspective, the wellspring of bedrock medications for anxiety disorders, depression, and schizophrenia was serendipitously discovered over 30 year ago, the swell of pharmaceutical investment in drug discovery has receded, and t...

journal_title：Frontiers in neuroscience

authors： Macdonald K,Feifel D

更新日期：2013-03-15 00:00:00

abstract：:The role of Histamine H3 receptors (H3Rs) in memory, and the prospective of H3R antagonists in pharmacological control of neurodegenerative disorders, e.g., Alzheimer disease (AD) is well-accepted. For that reason, the procognitive effects of the H3R antagonist DL77 on cognitive impairments induced with MK801 were tes...

journal_title：Frontiers in neuroscience

authors： Eissa N,Khan N,Ojha SK,Łazewska D,Kieć-Kononowicz K,Sadek B

更新日期：2018-02-12 00:00:00

abstract：:The ternary complex factor (TCF) Elk-1 is a transcription factor that regulates immediate early gene (IEG) expression via the serum response element (SRE) DNA consensus site. Elk-1 is associated with a dimer of serum response factor (SRF) at the SRE site, and its phosphorylation occurs at specific residues in response...

journal_title：Frontiers in neuroscience

authors： Besnard A,Galan-Rodriguez B,Vanhoutte P,Caboche J

更新日期：2011-03-16 00:00:00

abstract：:Luqin is a neuropeptide that was discovered and named on account of its expression in left upper quadrant cells of the abdominal ganglion in the mollusc Aplysia californica. Subsequently, luqin-type peptides were identified as cardio-excitatory neuropeptides in other molluscs and a cognate receptor was discovered in t...

journal_title：Frontiers in neuroscience

authors： Yañez-Guerra LA,Elphick MR

更新日期：2020-02-18 00:00:00

abstract：:The advent of large scale neural computational platforms has highlighted the lack of algorithms for synthesis of neural structures to perform predefined cognitive tasks. The Neural Engineering Framework (NEF) offers one such synthesis, but it is most effective for a spike rate representation of neural information, and...

journal_title：Frontiers in neuroscience

authors： Tapson JC,Cohen GK,Afshar S,Stiefel KM,Buskila Y,Wang RM,Hamilton TJ,van Schaik A

更新日期：2013-08-30 00:00:00

abstract：:This paper presents a real-time, low-complexity neuromorphic speech recognition system using a spiking silicon cochlea, a feature extraction module and a population encoding method based Neural Engineering Framework (NEF)/Extreme Learning Machine (ELM) classifier IC. Several feature extraction methods with varying mem...

journal_title：Frontiers in neuroscience

authors： Acharya J,Patil A,Li X,Chen Y,Liu SC,Basu A

更新日期：2018-03-28 00:00:00

abstract：:In this paper, we introduce a novel automatic method for Corpus Callosum (CC) in midsagittal plane segmentation. The robust segmentation of CC in midsagittal plane is key role for quantitative study of structural features of CC associated with various neurological disorder such as epilepsy, autism, Alzheimer's disease...

journal_title：Frontiers in neuroscience

authors： Park G,Kwak K,Seo SW,Lee JM

更新日期：2018-09-11 00:00:00