Natural Diterpenoid Oridonin Ameliorates Experimental Autoimmune Neuritis by Promoting Anti-inflammatory Macrophages Through Blocking Notch Pathway.

abstract：:The detection of mild cognitive impairment (MCI), the transitional stage between normal cognitive changes of aging and the cognitive decline caused by AD, is of paramount clinical importance, since MCI patients are at increased risk of progressing into AD. Electroencephalographic (EEG) alterations in the spectral cont...

journal_title：Frontiers in neuroscience

authors： Dimitriadis SI,Laskaris NA,Bitzidou MP,Tarnanas I,Tsolaki MN

更新日期：2015-10-20 00:00:00

abstract：:A P300 brain-computer interface (BCI) is a paradigm, where text characters are decoded from event-related potentials (ERPs). In a popular implementation, called P300 speller, a subject looks at a display where characters are flashing and selects one character by attending to it. The selection is recognized as the item...

journal_title：Frontiers in neuroscience

authors： Kirasirova L,Bulanov V,Ossadtchi A,Kolsanov A,Pyatin V,Lebedev M

更新日期：2020-12-03 00:00:00

abstract：:Pain and stress are both phenomena that challenge an individual's homeostasis and have significant overlap in conceptual and physiological processes. Allostasis is the ability to adapt to pain and stress and maintain homeostasis; however, if either process becomes chronic, it may result in negative long-term outcomes....

journal_title：Frontiers in neuroscience

authors： Lunde CE,Sieberg CB

更新日期：2020-03-26 00:00:00

abstract：Background:Postherpetic neuralgia (PHN) is a form of long-lasting neuropathic pain that can severely affect patients' quality of life. Pulsed radiofrequency (PRF) has been proven to be effective in treating PHN, but the optimal radiofrequency parameters are still not well defined. This retrospective study aimed to comp...

journal_title：Frontiers in neuroscience

authors： Han Z,Hong T,Ding Y,Wang S,Yao P

更新日期：2020-12-18 00:00:00

abstract：:Cognitive control of emotions depends on intermodular long-distance communications. However, negative connections between connector hubs are removed by traditional hard-thresholding approach in graph-theoretical research. Using soft-thresholding approach to reserve negative links, we explore time-varying features of c...

journal_title：Frontiers in neuroscience

authors： Zhang W,Chen J,Ren G,Tang F,Liu Q,Li H

更新日期：2019-10-25 00:00:00

abstract：:The molecular mechanism underlying Parkinson's disease (PD), an increasingly common neurodegenerative disease, remains unclear. Long non-coding RNA (lncRNA) plays essential roles in gene expression and human diseases. We hypothesize that lncRNAs are involved in neuronal degeneration of PD. Using microarray, we identif...

journal_title：Frontiers in neuroscience

authors： Fan Y,Li J,Yang Q,Gong C,Gao H,Mao Z,Yuan X,Zhu S,Xue Z

更新日期：2019-12-13 00:00:00

abstract：:The Golgi apparatus is a dynamic organelle involved in processing and sorting of lipids and proteins. In neurons, the Golgi apparatus is important for the development of axons and dendrites and maintenance of their highly complex polarized morphology. The motor protein complex cytoplasmic dynein has an important role ...

journal_title：Frontiers in neuroscience

authors： Jaarsma D,Hoogenraad CC

更新日期：2015-10-26 00:00:00

abstract：:Gangliosides are glycosphingolipids highly abundant in the nervous system, and carry most of the sialic acid residues in the brain. Gangliosides are enriched in cell membrane microdomains ("lipid rafts") and play important roles in the modulation of membrane proteins and ion channels, in cell signaling and in the comm...

journal_title：Frontiers in neuroscience

authors： Sipione S,Monyror J,Galleguillos D,Steinberg N,Kadam V

更新日期：2020-10-06 00:00:00

abstract：:Brain-derived neurotrophic factor (BDNF) is a potent regulator of neuronal development and synaptic plasticity that is fundamental to neural circuit formation and cognition. It is also involved in the control of appetite and body weight, with mutations in the genes for BDNF and its receptor, TrkB, resulting in remarka...

journal_title：Frontiers in neuroscience

authors： Vanevski F,Xu B

更新日期：2013-03-21 00:00:00

abstract：:Recent non-invasive brain stimulation techniques in combination with motor training can enhance neuroplasticity and learning. It is reasonable to assume that such neuroplasticity-based interventions constitute a useful rehabilitative tool for patients with Parkinson's Disease (PD). Regarding motor skill training, many...

journal_title：Frontiers in neuroscience

authors： Horiba M,Ueki Y,Nojima I,Shimizu Y,Sahashi K,Itamoto S,Suzuki A,Yamada G,Matsukawa N,Wada I

更新日期：2019-06-19 00:00:00

abstract：:There are few behavioral effects as ubiquitous as the speed-accuracy tradeoff (SAT). From insects to rodents to primates, the tendency for decision speed to covary with decision accuracy seems an inescapable property of choice behavior. Recently, the SAT has received renewed interest, as neuroscience approaches begin ...

journal_title：Frontiers in neuroscience

authors： Heitz RP

更新日期：2014-06-11 00:00:00

abstract：:Heterogeneity between late-onset Parkinson's disease (LOPD) and early-onset Parkinson's disease (EOPD) is mainly reflected in the following aspects including genetics, disease progression, drug response, clinical manifestation, and neuropathological change. Although many studies have investigated these differences in ...

journal_title：Frontiers in neuroscience

authors： Yue Y,Jiang Y,Shen T,Pu J,Lai HY,Zhang B

更新日期：2020-02-25 00:00:00

abstract：:There is increasing evidence of associations between the presence of temporomandibular joint (TMJ) disorders and tinnitus. It has been recently proposed that tinnitus patients with TMJ complaints could constitute a subtype, meaning a subgroup of tinnitus patients responsive to specific treatments. Tinnitus patients wi...

journal_title：Frontiers in neuroscience

authors： Edvall NK,Gunan E,Genitsaridi E,Lazar A,Mehraei G,Billing M,Tullberg M,Bulla J,Whitton J,Canlon B,Hall DA,Cederroth CR

更新日期：2019-08-22 00:00:00

abstract：:A patient with early achalasia presented spontaneous strong rhythmic non-propulsive contractions at ~7/min, independent of swallows. Our aim was to evaluate characteristics of the rhythmic contractions, provide data on the structure of pacemaker cells in the esophagus and discuss a potential role for interstitial cell...

journal_title：Frontiers in neuroscience

authors： Chen JH,Wang XY,Liu LW,Yu W,Yu Y,Zhao L,Huizinga JD

更新日期：2013-05-21 00:00:00

abstract：:Aversive memory is essential for survival, but in some situations its exacerbation can be potentially dangerous. There are several ways to modulate memory, among them, through stress-related hormones physiological release or administration of exogenous substances analogous to them. Recently, our group shown that a chr...

journal_title：Frontiers in neuroscience

authors： Gonçalves R,de Vargas LDS,Mello-Carpes PB

更新日期：2019-10-31 00:00:00

abstract：:Obesity continues to be one of the major public health problems due to its high prevalence and co-morbidities. Common co-morbidities not only include cardiometabolic disorders but also mood and cognitive disorders. Obese subjects often show deficits in memory, learning and executive functions compared to normal weight...

journal_title：Frontiers in neuroscience

authors： Agustí A,García-Pardo MP,López-Almela I,Campillo I,Maes M,Romaní-Pérez M,Sanz Y

更新日期：2018-03-16 00:00:00

abstract：:Ever since the modern rediscovery of psychedelic substances by Western society, several authors have independently proposed that their effects bear a high resemblance to the dreams and dreamlike experiences occurring naturally during the sleep-wake cycle. Recent studies in humans have provided neurophysiological evide...

journal_title：Frontiers in neuroscience

authors： Sanz C,Zamberlan F,Erowid E,Erowid F,Tagliazucchi E

更新日期：2018-01-22 00:00:00

abstract：:A large body of experimental and clinical evidence has strongly suggested that monoamines play an important role in regulating epileptogenesis, seizure susceptibility, convulsions, and comorbid psychiatric disorders commonly seen in people with epilepsy (PWE). However, neither the relative significance of individual m...

journal_title：Frontiers in neuroscience

authors： Svob Strac D,Pivac N,Smolders IJ,Fogel WA,De Deurwaerdere P,Di Giovanni G

更新日期：2016-11-10 00:00:00

abstract：:Corticotropin-releasing factor (CRF) is a 41-amino acid neuropeptide that is involved in stress-related physiology and behavior, including control of the hypothalamic-pituitary-adrenal (HPA) axis. Members of the CRF family of neuropeptides, including urocortin 1 (UCN 1), UCN 2, and UCN 3, bind to the G protein-coupled...

journal_title：Frontiers in neuroscience

authors： Fox JH,Lowry CA

更新日期：2013-09-20 00:00:00

abstract：:The sleep duration of adolescents has continued to decline over the past 20 years. Sleep insufficiency is one of the most important risk factors for obesity, but the mechanisms underlying the association are unclear. Therefore, the hypothalamic-regulated mechanisms of appetite and the circadian clock gene expression w...

journal_title：Frontiers in neuroscience

authors： Sun Q,Liu Y,Wei W,Wu D,Lin R,Wen D,Jia L

更新日期：2020-09-08 00:00:00

abstract：:Gene Expression Programming (GEP), a variant of Genetic Programming (GP), is a well established technique for automatic generation of computer programs. Due to the flexible representation, GEP has long been concerned as a classification algorithm for various applications. Whereas, GEP cannot be extended to multi-class...

journal_title：Frontiers in neuroscience

authors： Wei T,Zhong J

更新日期：2020-01-17 00:00:00

abstract：:Value-based decision making relies on distributed neural systems that weigh the benefits of actions against the cost required to obtain a given outcome. Perturbations of these systems are thought to underlie abnormalities in action selection seen across many neuropsychiatric disorders. Genetic tools in mice provide a ...

journal_title：Frontiers in neuroscience

authors： Alabi OO,Fortunato MP,Fuccillo MV

更新日期：2019-02-07 00:00:00

abstract：:Event-related potential (ERP) studies using the task-switching paradigm show that multiple ERP components are modulated by activation of proactive control processes involved in preparing to repeat or switch task and reactive control processes involved in implementation of the current or new task. Our understanding of ...

journal_title：Frontiers in neuroscience

authors： Wong ASW,Cooper PS,Conley AC,McKewen M,Fulham WR,Michie PT,Karayanidis F

更新日期：2018-03-08 00:00:00

abstract：Background:Early exposure to nociceptive events may cause brain structural alterations in preterm neonates, with long-lasting consequences on neurodevelopmental outcome. Little is known on the extent to which early pain may affect brain connectivity. We aim to evaluate brain functional connectivity changes in preterm n...

journal_title：Frontiers in neuroscience

authors： Tortora D,Severino M,Di Biase C,Malova M,Parodi A,Minghetti D,Traggiai C,Uccella S,Boeri L,Morana G,Rossi A,Ramenghi LA

更新日期：2019-08-23 00:00:00

abstract：:Bispectral analysis is a signal processing technique that makes it possible to capture the non-linear and non-Gaussian properties of the EEG signals. It has found various applications in EEG research and clinical practice, including the assessment of anesthetic depth, the identification of epileptic seizures, and more...

journal_title：Frontiers in neuroscience

authors： Chella F,D'Andrea A,Basti A,Pizzella V,Marzetti L

更新日期：2017-05-16 00:00:00

abstract：:Although the interplay between endogenous opioids and dopamine (DA) in the basal ganglia (BG) is known to underlie diverse motor functions, few studies exist on their role in modulating speech and vocalization. Vocal impairment is a common symptom of Parkinson's disease (PD), wherein DA depletion affects striosomes ri...

journal_title：Frontiers in neuroscience

authors： Kumar S,Mohapatra AN,Sharma HP,Singh UA,Kambi NA,Velpandian T,Rajan R,Iyengar S

更新日期：2019-07-03 00:00:00

abstract：:We implemented least absolute shrinkage and selection operator (LASSO) regression to evaluate gene effects in genome-wide association studies (GWAS) of brain images, using an MRI-derived temporal lobe volume measure from 729 subjects scanned as part of the Alzheimer's Disease Neuroimaging Initiative (ADNI). Sparse gro...

journal_title：Frontiers in neuroscience

authors： Kohannim O,Hibar DP,Stein JL,Jahanshad N,Hua X,Rajagopalan P,Toga AW,Jack CR Jr,Weiner MW,de Zubicaray GI,McMahon KL,Hansell NK,Martin NG,Wright MJ,Thompson PM,Alzheimer’s Disease Neuroimaging Initiative.

更新日期：2012-08-06 00:00:00

abstract：:Poor postoperative pain (POP) control increases perioperative morbidity, prolongs hospitalization days, and causes chronic pain. However, the specific mechanism(s) underlying POP is unclear and the identification of optimal perioperative treatment remains elusive. Akt and mammalian target of rapamycin (mTOR) are expre...

journal_title：Frontiers in neuroscience

authors： Xu B,Liu SS,Wei J,Jiao ZY,Mo C,Lv CM,Huang AL,Chen QB,Ma L,Guan XH

更新日期：2020-07-22 00:00:00

abstract：:Neurodegenerative diseases are among the leading causes of disability and death worldwide. The disease-related socioeconomic burden is expected to increase with the steadily increasing life expectancy. In spite of decades of clinical and basic research, most strategies designed to manage degenerative brain diseases ar...

journal_title：Frontiers in neuroscience

authors： Castillo X,Castro-Obregón S,Gutiérrez-Becker B,Gutiérrez-Ospina G,Karalis N,Khalil AA,Lopez-Noguerola JS,Rodríguez LL,Martínez-Martínez E,Perez-Cruz C,Pérez-Velázquez J,Piña AL,Rubio K,García HPS,Syeda T,Vanoye-Carlo A,Vi

更新日期：2019-07-24 00:00:00

abstract：:The mechanisms by which glucocorticoids regulate food intake and resulting body mass in humans are not well-understood. One potential mechanism could involve modulation of reward processing, but human stress models examining effects of glucocorticoids on behavior contain important confounds. Here, we studied individua...

journal_title：Frontiers in neuroscience

authors： Moeller SJ,Couto L,Cohen V,Lalazar Y,Makotkine I,Williams N,Yehuda R,Goldstein RZ,Geer EB

更新日期：2016-02-05 00:00:00