Chronic Timed Sleep Restriction Attenuates LepRb-Mediated Signaling Pathways and Circadian Clock Gene Expression in the Rat Hypothalamus.

abstract：:Ablation of adult neurogenesis in mice has revealed that young adult-born granule cells (abGCs) are required for some of the behavioral responses to antidepressants (ADs), yet the mechanism by which abGCs contribute to AD action remains unknown. During their maturation process, these immature neurons exhibit unique pr...

journal_title：Frontiers in neuroscience

authors： Tannenholz L,Hen R,Kheirbek MA

更新日期：2016-05-31 00:00:00

abstract：:Analog arrays are a promising emerging hardware technology with the potential to drastically speed up deep learning. Their main advantage is that they employ analog circuitry to compute matrix-vector products in constant time, irrespective of the size of the matrix. However, ConvNets map very unfavorably onto analog a...

journal_title：Frontiers in neuroscience

authors： Rasch MJ,Gokmen T,Rigotti M,Haensch W

更新日期：2019-07-30 00:00:00

abstract：:The field of neuroimaging has embraced the need for sharing and collaboration. Data sharing mandates from public funding agencies and major journal publishers have spurred the development of data repositories and neuroinformatics consortia. However, efficient and effective data sharing still faces several hurdles. For...

journal_title：Frontiers in neuroscience

authors： Plis SM,Sarwate AD,Wood D,Dieringer C,Landis D,Reed C,Panta SR,Turner JA,Shoemaker JM,Carter KW,Thompson P,Hutchison K,Calhoun VD

更新日期：2016-08-19 00:00:00

abstract：:Cerebral function is associated with exceptionally high metabolic activity, and requires continuous supply of oxygen and nutrients from the blood stream. Since the mid-twentieth century the idea that brain energy metabolism is coupled to neuronal activity has emerged, and a number of studies supported this hypothesis....

journal_title：Frontiers in neuroscience

authors： Sonnay S,Gruetter R,Duarte JMN

更新日期：2017-05-26 00:00:00

abstract：:Changes in sleep behavior and sleep-related cortical activity have been reported in conditions associated with abnormal alpha-synuclein (α-syn) expression, in particular Parkinson's disease (PD) and dementia with Lewy bodies (DLB). Notably, changes can occur in patients years before the onset of cognitive decline. Sle...

journal_title：Frontiers in neuroscience

authors： Stylianou M,Zaaimi B,Thomas A,Taylor JP,LeBeau FEN

更新日期：2020-09-17 00:00:00

abstract：:Selection of the time-window mainly affects the effectiveness of piecewise feature extraction procedures. We present an enhanced bag-of-patterns representation that allows capturing the higher-level structures of brain dynamics within a wide window range. So, we introduce augmented instance representations with extend...

journal_title：Frontiers in neuroscience

authors： Collazos-Huertas D,Caicedo-Acosta J,Castaño-Duque GA,Acosta-Medina CD

更新日期：2020-02-25 00:00:00

abstract：:Transcranial direct current stimulation (tDCS) is a non-invasive brain stimulation technique to change cortical excitability. Its effects are shown for cognitive processing, and behavior in the motor and perceptual domains. However, evidence of tDCS effects in the perceptual domain particularly for auditory processing...

journal_title：Frontiers in neuroscience

authors： Kunzelmann K,Meier L,Grieder M,Morishima Y,Dierks T

更新日期：2018-11-27 00:00:00

abstract：:Motor recovery following nerve transfer surgery depends on the successful re-innervation of the new target muscle by regenerating axons. Cortical plasticity and motor relearning also play a major role during functional recovery. Successful neuromuscular rehabilitation requires detailed afferent feedback. Surface elect...

journal_title：Frontiers in neuroscience

authors： Sturma A,Hruby LA,Prahm C,Mayer JA,Aszmann OC

更新日期：2018-12-04 00:00:00

abstract：:Diffusible ions (Na+, K+, Mg2+, Ca2+, Cl-) are vital for healthy function of all cells, especially brain cells. Unfortunately, the diffusible nature of these ions renders them difficult to study with traditional microscopy in situ within ex vivo brain tissue sections. This mini-review examines the recent progress in t...

journal_title：Frontiers in neuroscience

authors： Hartnell D,Andrews W,Smith N,Jiang H,McAllum E,Rajan R,Colbourne F,Fitzgerald M,Lam V,Takechi R,Pushie MJ,Kelly ME,Hackett MJ

更新日期：2020-01-22 00:00:00

abstract：:Non-linguistic sounds (NLSs) are a core feature of our everyday life and many evoke powerful cognitive and emotional outcomes. The subjective perception of NLSs by humans has occasionally been defined for single percepts, e.g., their pleasantness, whereas many NLSs evoke multiple perceptions. There has also been very ...

journal_title：Frontiers in neuroscience

authors： Burns T,Rajan R

更新日期：2019-07-31 00:00:00

abstract：:The bladder is innervated by extrinsic afferents that project into the dorsal horn of the spinal cord, providing sensory input to the micturition centers within the central nervous system. Under normal conditions, the continuous activation of these neurons during bladder distension goes mostly unnoticed. However, for ...

journal_title：Frontiers in neuroscience

authors： Grundy L,Caldwell A,Brierley SM

更新日期：2018-12-12 00:00:00

abstract：Background:Since subjective cognitive decline (SCD) was standardized in 2014, many studies have investigated its features. However, the risk of SCD (plus) progressing to AD is much higher, and yet there have been few studies reporting the risk factors and neuropsychological assessment characteristics of SCD (plus). Ob...

journal_title：Frontiers in neuroscience

authors： Hao L,Xing Y,Li X,Mu B,Zhao W,Wang G,Wang T,Jia J,Han Y

更新日期：2019-08-14 00:00:00

abstract：:[This retracts the article on p. 303 in vol. 10, PMID: 27445673.]. ...

journal_title：Frontiers in neuroscience

authors： Frontiers Editorial Office.

更新日期：2016-10-07 00:00:00

abstract：:Mutations in leucine-rich repeat kinase 2 (LRRK2) instigate an autosomal dominant form of Parkinson's disease (PD). Despite the neuropathological heterogeneity observed in LRRK2-PD, accumulating evidence suggests that alpha-synuclein and tau pathology are observed in a vast majority of cases. Intriguingly, the presenc...

journal_title：Frontiers in neuroscience

authors： Dues DJ,Moore DJ

更新日期：2020-07-08 00:00:00

abstract：:Extrapancreatic nerves project to pancreatic islets directly or converge onto intrapancreatic ganglia. Intrapancreatic ganglia constitute a complex information-processing center that contains various neurotransmitters and forms an endogenous neural network. Both intrapancreatic ganglia and extrapancreatic nerves have ...

journal_title：Frontiers in neuroscience

authors： Li W,Yu G,Liu Y,Sha L

更新日期：2019-02-20 00:00:00

abstract：:This paper reports on a benchmark dataset acquired with a brain-computer interface (BCI) system based on the rapid serial visual presentation (RSVP) paradigm. The dataset consists of 64-channel electroencephalogram (EEG) data from 64 healthy subjects (sub1,…, sub64) while they performed a target image detection task. ...

journal_title：Frontiers in neuroscience

authors： Zhang S,Wang Y,Zhang L,Gao X

更新日期：2020-10-02 00:00:00

abstract：:In this paper we review several ways of realizing asynchronous Spike-Timing-Dependent-Plasticity (STDP) using memristors as synapses. Our focus is on how to use individual memristors to implement synaptic weight multiplications, in a way such that it is not necessary to (a) introduce global synchronization and (b) to ...

journal_title：Frontiers in neuroscience

authors： Serrano-Gotarredona T,Masquelier T,Prodromakis T,Indiveri G,Linares-Barranco B

更新日期：2013-02-18 00:00:00

abstract：:Alzheimer's disease (AD) is a progressive brain disorder with gradual memory loss that correlates to cognitive deficits in the elderly population. Recent studies have shown the potentials of machine learning algorithms to identify biomarkers and functional brain activity patterns across various AD stages using electro...

journal_title：Frontiers in neuroscience

authors： Fan M,Yang AC,Fuh JL,Chou CA

更新日期：2018-10-04 00:00:00

abstract：:Pain and stress are both phenomena that challenge an individual's homeostasis and have significant overlap in conceptual and physiological processes. Allostasis is the ability to adapt to pain and stress and maintain homeostasis; however, if either process becomes chronic, it may result in negative long-term outcomes....

journal_title：Frontiers in neuroscience

authors： Lunde CE,Sieberg CB

更新日期：2020-03-26 00:00:00

abstract：:Motor neurons (MN) degeneration is a main feature of amyotrophic lateral sclerosis (ALS), a neurological disorder with a progressive course. The diagnosis of ALS is essentially a clinical one. Most common symptoms include a gradual neurological deterioration that reflect the impairment and subsequent loss of muscle fu...

journal_title：Frontiers in neuroscience

authors： Forostyak S,Sykova E

更新日期：2017-10-24 00:00:00

abstract：:The global prevalence of obesity has been steadily increasing. Although pharmacotherapy and bariatric surgeries can be useful adjuvants in the treatment of morbid obesity, they may lose long-term effectiveness. Obesity result largely from unbalanced energy homeostasis. Palatable and densely caloric foods may affect th...

journal_title：Frontiers in neuroscience

authors： Formolo DA,Gaspar JM,Melo HM,Eichwald T,Zepeda RJ,Latini A,Okun MS,Walz R

更新日期：2019-04-18 00:00:00

abstract：:This paper introduces Pyff, the Pythonic feedback framework for feedback applications and stimulus presentation. Pyff provides a platform-independent framework that allows users to develop and run neuroscientific experiments in the programming language Python. Existing solutions have mostly been implemented in C++, wh...

journal_title：Frontiers in neuroscience

authors： Venthur B,Scholler S,Williamson J,Dähne S,Treder MS,Kramarek MT,Müller KR,Blankertz B

更新日期：2010-12-02 00:00:00

abstract：:Tau is an essential protein that physiologically promotes the assembly and stabilization of microtubules, and participates in neuronal development, axonal transport, and neuronal polarity. However, in a number of neurodegenerative diseases, including Alzheimer's disease (AD), tau undergoes pathological modifications i...

journal_title：Frontiers in neuroscience

authors： Pérez MJ,Jara C,Quintanilla RA

更新日期：2018-07-05 00:00:00

abstract：:Recent non-invasive brain stimulation techniques in combination with motor training can enhance neuroplasticity and learning. It is reasonable to assume that such neuroplasticity-based interventions constitute a useful rehabilitative tool for patients with Parkinson's Disease (PD). Regarding motor skill training, many...

journal_title：Frontiers in neuroscience

authors： Horiba M,Ueki Y,Nojima I,Shimizu Y,Sahashi K,Itamoto S,Suzuki A,Yamada G,Matsukawa N,Wada I

更新日期：2019-06-19 00:00:00

abstract：:Voltage-gated calcium channels (VGCCs) are important mediators of pain hypersensitivity during inflammatory states, but their role in sensory nerve growth remains underexplored. Here, we assess the role of the N-type calcium channel Cav2.2 in the complete Freund's adjuvant (CFA) model of inflammatory pain. We demonstr...

journal_title：Frontiers in neuroscience

authors： Pitake S,Middleton LJ,Abdus-Saboor I,Mishra SK

更新日期：2019-09-19 00:00:00

abstract：:Blood-brain barrier opening (BBBO) with pulsed Focused Ultrasound (pFUS) and microbubbles (MB) has received increasing interest as a method for neurotherapeutics of the central nervous system. In general, conventional MRI [i.e., T2w, T2∗w, gadolinium (Gd) enhanced T1w] is used to monitor the effects of pFUS+MB on BBBO...

journal_title：Frontiers in neuroscience

authors： Tu TW,Kovacs ZI,Sundby M,Witko JA,Papadakis GZ,Reid WC,Hammoud DA,Frank JA

更新日期：2020-08-25 00:00:00

abstract：:While convolutional neural networks (CNNs) continue to renew state-of-the-art performance across many fields of machine learning, their hardware implementations tend to be very costly and inflexible. Neuromorphic hardware, on the other hand, targets higher efficiency but their inference accuracy lags far behind that o...

journal_title：Frontiers in neuroscience

authors： Sim H,Lee J

更新日期：2020-12-23 00:00:00

abstract：:The comprehension of fluent speech in one's native language requires that listeners integrate the detailed acoustic-phonetic information available in the sound signal with linguistic knowledge. This interplay is especially apparent in the phoneme restoration effect, a phenomenon in which a missing phoneme is "restored...

journal_title：Frontiers in neuroscience

authors： Del Tufo SN,Myers EB

更新日期：2014-06-04 00:00:00

abstract：:In mammals, new neurons in the adult olfactory bulb originate from a pool of neural stem cells in the subventricular zone of the lateral ventricles. Adult-born cells play an important role in odor information processing by adjusting the neuronal network to changing environmental conditions. Olfactory bulb neurogenesis...

journal_title：Frontiers in neuroscience

authors： Gengatharan A,Bammann RR,Saghatelyan A

更新日期：2016-04-05 00:00:00

abstract：:Transcutaneous vagus nerve stimulation (tVNS) is widely used for clinical applications, but its mechanism of action is poorly understood. One candidate pathway that might mediate the effects of tVNS is an increase in GABAergic neurotransmission. In this study, we investigated the effect of tVNS on visual bistable perc...

journal_title：Frontiers in neuroscience

authors： Keute M,Boehrer L,Ruhnau P,Heinze HJ,Zaehle T

更新日期：2019-03-08 00:00:00