Walking the Tightrope: A Proposed Model of Chronic Pain and Stress.

abstract：:Luqin is a neuropeptide that was discovered and named on account of its expression in left upper quadrant cells of the abdominal ganglion in the mollusc Aplysia californica. Subsequently, luqin-type peptides were identified as cardio-excitatory neuropeptides in other molluscs and a cognate receptor was discovered in t...

journal_title：Frontiers in neuroscience

authors： Yañez-Guerra LA,Elphick MR

更新日期：2020-02-18 00:00:00

abstract：:We present a spiking neural network model of the thalamic Lateral Geniculate Nucleus (LGN) developed on SpiNNaker, which is a state-of-the-art digital neuromorphic hardware built with very-low-power ARM processors. The parallel, event-based data processing in SpiNNaker makes it viable for building massively parallel n...

journal_title：Frontiers in neuroscience

authors： Sen-Bhattacharya B,Serrano-Gotarredona T,Balassa L,Bhattacharya A,Stokes AB,Rowley A,Sugiarto I,Furber S

更新日期：2017-08-09 00:00:00

abstract：:A lack of sleep is linked with a range of inner ear diseases, including hearing loss and tinnitus. Here, we used a mouse model to investigate the effects of sleep deprivation (SD) on noise vulnerability, and explored the mechanisms that might be involved in vitro, focusing particularly corticosterone levels and autoph...

journal_title：Frontiers in neuroscience

authors： Li P,Bing D,Wang S,Chen J,Du Z,Sun Y,Qi F,Zhang Y,Chu H

更新日期：2019-11-29 00:00:00

abstract：:Astrocytes are the most abundant type of glial cell in the central nervous system and perform a myriad of vital functions, however, the nature of their diversity remains a longstanding question in neuroscience. Using transcription factor motif discovery analysis on region-specific gene signatures from astrocytes we un...

journal_title：Frontiers in neuroscience

authors： Lozzi B,Huang TW,Sardar D,Huang AY,Deneen B

更新日期：2020-02-21 00:00:00

abstract：:This work presents sPyNNaker 4.0.0, the latest version of the software package for simulating PyNN-defined spiking neural networks (SNNs) on the SpiNNaker neuromorphic platform. Operations underpinning realtime SNN execution are presented, including an event-based operating system facilitating efficient time-driven ne...

journal_title：Frontiers in neuroscience

authors： Rhodes O,Bogdan PA,Brenninkmeijer C,Davidson S,Fellows D,Gait A,Lester DR,Mikaitis M,Plana LA,Rowley AGD,Stokes AB,Furber SB

更新日期：2018-11-20 00:00:00

abstract：:The utility of premovement electroencephalography (EEG) for decoding movement intention during a reaching task has been demonstrated. However, the kind of information the brain represents regarding the intended target during movement preparation remains unknown. In the present study, we investigated which movement par...

journal_title：Frontiers in neuroscience

authors： Kim H,Yoshimura N,Koike Y

更新日期：2019-11-01 00:00:00

abstract：:The Artificial Intelligence (AI) revolution foretold of during the 1960s is well underway in the second decade of the twenty first century. Its period of phenomenal growth likely lies ahead. AI-operated machines and technologies will extend the reach of Homo sapiens far beyond the biological constraints imposed by evo...

journal_title：Frontiers in neuroscience

authors： Krichmar JL,Severa W,Khan MS,Olds JL

更新日期：2019-06-27 00:00:00

abstract：:The ability to delegate control over repetitive tasks from higher to lower neural centers may be a fundamental innovation in human cognition. Plausibly, the massive neurocomputational challenges associated with the mastery of balance during the evolution of bipedality in proto-humans provided a strong selective advant...

journal_title：Frontiers in neuroscience

authors： Shine JM,Shine R

更新日期：2014-04-29 00:00:00

abstract：:Perinatal exposure to endocrine disrupting chemicals (EDCs) can induce promiscuous neurobehavioral disturbances. Bisphenol A and phthalates are two widely prevalent and persistent EDCs reported to lead to such effects. Parental and social behaviors are especially vulnerable to endocrine disruption, as these traits are...

journal_title：Frontiers in neuroscience

authors： Rosenfeld CS

更新日期：2015-03-03 00:00:00

abstract：:The Embden-Meyerhof-Parnas (EMP) pathway comprises eleven cytosolic enzymes interacting to metabolize glucose to lactic acid [CH3CH(OH)COOH]. Glycolysis is largely considered as the conversion of glucose to pyruvate (CH3COCOO-). We consider glycolysis to be a cellular process and as such, transporters mediating glucos...

journal_title：Frontiers in neuroscience

authors： Roosterman D,Meyerhof W,Cottrell GS

更新日期：2018-06-15 00:00:00

abstract：Background:Cranial irradiation is a common therapy for the treatment of brain tumors, but unfortunately patients suffer from side effects, particularly cognitive impairment, caused by neurodegenerative and neuroinflammatory mechanisms. Finding a therapeutic agent protecting hippocampal neurons would be beneficial. Fing...

journal_title：Frontiers in neuroscience

authors： Metzdorf J,Hobloss Z,Schlevogt S,Ayzenberg I,Stahlke S,Pedreiturria X,Haupeltshofer S,Gold R,Tönges L,Kleiter I

更新日期：2019-07-09 00:00:00

abstract：:In this paper, we introduce a novel automatic method for Corpus Callosum (CC) in midsagittal plane segmentation. The robust segmentation of CC in midsagittal plane is key role for quantitative study of structural features of CC associated with various neurological disorder such as epilepsy, autism, Alzheimer's disease...

journal_title：Frontiers in neuroscience

authors： Park G,Kwak K,Seo SW,Lee JM

更新日期：2018-09-11 00:00:00

abstract：:A growing understanding of music therapy with patients with disorders of consciousness (DOC) has developed from observing behavioral changes and using these to gain new ways of experiencing this research environment and setting. Neuroscience provides further insight into the effects of music therapy; however, various ...

journal_title：Frontiers in neuroscience

authors： Vogl J,Heine AM,Steinhoff N,Weiss K,Tucek G

更新日期：2015-08-04 00:00:00

abstract：:We introduce a novel recurrent neural network (RNN) approach to account for temporal dynamics and dependencies in brain networks observed via functional magnetic resonance imaging (fMRI). Our approach directly parameterizes temporal dynamics through recurrent connections, which can be used to formulate blind source se...

journal_title：Frontiers in neuroscience

authors： Hjelm RD,Damaraju E,Cho K,Laufs H,Plis SM,Calhoun VD

更新日期：2018-09-20 00:00:00

abstract：:The aim of this study was to explore changes in intracellular ATP generation and tight junction protein expression during the course of brain edema induced by subacute poisoning of 1,2-dichloroethane (1,2-DCE). Mice were exposed to 1.2 g/m3 1,2-DCE for 3.5 h per day for 1, 2, or 3 days, namely group A, B, and C. Na+-K...

journal_title：Frontiers in neuroscience

authors： Wang G,Yuan Y,Gao L,Tan X,Yang G,Zhao F,Jin Y

更新日期：2018-01-23 00:00:00

abstract：:Poisoning with organophosphorus compounds (OPCs) is a major problem worldwide. Standard therapy with atropine and established oxime-type enzyme reactivators (pralidoxime, obidoxime) is unsatisfactory. In search of more efficacious broad-spectrum oximes, new bispyridinium (K-) oximes have been synthesized, with K027 be...

journal_title：Frontiers in neuroscience

authors： Lorke DE,Petroianu GA

更新日期：2019-05-22 00:00:00

abstract：:Previous studies have demonstrated that total flavonoid extracts from Caragana sinica (TFC) exert multiple therapeutic effects, promote blood flow, and exhibit anti-inflammatory and antioxidant properties. The present study aimed to investigate whether TFC promotes angiogenesis and exerts neuroprotective effects in a ...

journal_title：Frontiers in neuroscience

authors： He Q,Li S,Li L,Hu F,Weng N,Fan X,Kuang S

更新日期：2018-09-12 00:00:00

abstract：:Induction of lordosis as typical female sexual behavior in rodents is dependent on a mount stimulus from males and blood levels of estrogen. Periaqueductal gray (PAG) efferent neurons have been suggested to be important for lordosis behavior; however, the neurochemical basis remains to be understood. In this study, we...

journal_title：Frontiers in neuroscience

authors： Yamada S,Kawata M

更新日期：2014-12-18 00:00:00

abstract：:Evidence obtained in recent years in a few species, especially rainbow trout, supports the presence in fish of nutrient sensing mechanisms. Glucosensing capacity is present in central (hypothalamus and hindbrain) and peripheral [liver, Brockmann bodies (BB, main accumulation of pancreatic endocrine cells in several fi...

journal_title：Frontiers in neuroscience

authors： Conde-Sieira M,Soengas JL

更新日期：2017-01-05 00:00:00

abstract：:Recent studies have shown the ability to record high-γ signals (80-160 Hz) in electroencephalogram (EEG) from traumatic brain injury (TBI) patients who have had hemicraniectomies. However, extraction of the movement-related high-γ remains challenging due to a confounding bandwidth overlap with surface electromyogram (...

journal_title：Frontiers in neuroscience

authors： Li Y,Wang PT,Vaidya MP,Flint RD,Liu CY,Slutzky MW,Do AH

更新日期：2020-11-24 00:00:00

abstract：:The classification of electroencephalogram (EEG) signals is of significant importance in brain-computer interface (BCI) systems. Aiming to achieve intelligent classification of EEG types with high accuracy, a classification methodology using sparse representation (SR) and fast compression residual convolutional neural...

journal_title：Frontiers in neuroscience

authors： Huang JS,Li Y,Chen BQ,Lin C,Yao B

更新日期：2020-09-30 00:00:00

abstract：:Some toxins and drugs can trigger lasting neuroprotective mechanisms that enable neurons to resist a subsequent severe insult. This "pharmacological preconditioning" has far-reaching implications for conditions in which blood flow to the brain is interrupted. We have previously shown that in vitro preconditioning with...

journal_title：Frontiers in neuroscience

authors： Goulton CS,Patten AR,Kerr JR,Kerr DS

更新日期：2010-08-03 00:00:00

abstract：:The hippocampus has exhibited navigation-related changes in volume and activity after visual deprivation; however, the resting-state functional connectivity (rsFC) changes of the hippocampus in the blind remains unknown. In this study, we focused on sub-region-specific rsFC changes of the hippocampus and their associa...

journal_title：Frontiers in neuroscience

authors： Ma G,Yang D,Qin W,Liu Y,Jiang T,Yu C

更新日期：2017-01-10 00:00:00

abstract：:Pitch is an essential category for musical sensations. Models of pitch perception are vividly discussed up to date. Most of them rely on definitions of mathematical methods in the spectral or temporal domain. Our proposed pitch perception model is composed of an active auditory model extended by octopus cells. The act...

journal_title：Frontiers in neuroscience

authors： Harczos T,Klefenz FM

更新日期：2018-09-25 00:00:00

abstract：:The habenular neural circuit is attracting increasing attention from researchers in fields as diverse as neuroscience, medicine, behavior, development, and evolution. Recent studies have revealed that this part of the limbic system in the dorsal diencephalon is involved in reward, addiction, and other behaviors and it...

journal_title：Frontiers in neuroscience

authors： Beretta CA,Dross N,Guiterrez-Triana JA,Ryu S,Carl M

更新日期：2012-04-23 00:00:00

abstract：:Whereas major insights into the neuronal basis of adaptive behavior have been gained from the study of automatic behaviors, including reflexive and rhythmic motor acts, the neural substrates for goal-directed behaviors in which decision-making about action selection and initiation are crucial, remain poorly understood...

journal_title：Frontiers in neuroscience

authors： Nargeot R,Simmers J

更新日期：2012-07-26 00:00:00

abstract：:The subventricular zone (SVZ) contains neural stem cells (NSCs) that generate new neurons throughout life. Many brain diseases stimulate NSCs proliferation, neuronal differentiation and homing of these newborns cells into damaged regions. However, complete cell replacement has never been fully achieved. Hence, the ide...

journal_title：Frontiers in neuroscience

authors： Eiriz MF,Valero J,Malva JO,Bernardino L

更新日期：2014-06-16 00:00:00

abstract：:Alzheimer's disease (AD) is a progressive mental illness characterized by memory loss and multiple cognitive impairments. In the last several decades, significant progress has been made in understanding basic biology, molecular mechanisms, and development of biomarkers and therapeutic drugs. Multiple cellular changes ...

journal_title：Frontiers in neuroscience

authors： Amakiri N,Kubosumi A,Tran J,Reddy PH

更新日期：2019-05-03 00:00:00

abstract：:In this paper we review several ways of realizing asynchronous Spike-Timing-Dependent-Plasticity (STDP) using memristors as synapses. Our focus is on how to use individual memristors to implement synaptic weight multiplications, in a way such that it is not necessary to (a) introduce global synchronization and (b) to ...

journal_title：Frontiers in neuroscience

authors： Serrano-Gotarredona T,Masquelier T,Prodromakis T,Indiveri G,Linares-Barranco B

更新日期：2013-02-18 00:00:00

abstract：:Alcoholism is a serious public health concern that is characterized by the development of tolerance to alcohol's effects, increased consumption, loss of control over drinking and the development of physical dependence. This cycle is often times punctuated by periods of abstinence, craving and relapse. The development ...

journal_title：Frontiers in neuroscience

authors： Rao PS,Bell RL,Engleman EA,Sari Y

更新日期：2015-04-23 00:00:00