The Experimental Oxime K027-A Promising Protector From Organophosphate Pesticide Poisoning. A Review Comparing K027, K048, Pralidoxime, and Obidoxime.

abstract：:Recent studies have identified the Drosophila brain circuits involved in the sleep/wake switch and have pointed to the modulation of neuronal excitability as one of the underlying mechanisms triggering sleep need. In this study we aimed to explore the link between the homeostatic regulation of neuronal excitability an...

journal_title：Frontiers in neuroscience

authors： De Jesús-Olmo LA,Rodríguez N,Francia M,Alemán-Rios J,Pacheco-Agosto CJ,Ortega-Torres J,Nieves R,Fuenzalida-Uribe N,Ghezzi A,Agosto JL

更新日期：2020-04-17 00:00:00

abstract：:Here, we present the first description of an isolation syndrome in a patient who suffered prolonged cardiac arrest and underwent a standard therapeutic hypothermia protocol. Two years after the arrest, the patient demonstrated no motor responses to commands, communication capabilities, or visual tracking at the bedsid...

journal_title：Frontiers in neuroscience

authors： Forgacs PB,Fridman EA,Goldfine AM,Schiff ND

更新日期：2016-06-09 00:00:00

abstract：:Emerging evidence suggest an impaired endocannabinoid activity in the pathophysiology of binge eating disorder (BED). Herein, we investigated whether endocannabinoid tone could be modified as a consequence of dietary-induced binge eating in female rats. For this purpose, brain levels of the endocannabinoids anandamide...

journal_title：Frontiers in neuroscience

authors： Satta V,Scherma M,Piscitelli F,Usai P,Castelli MP,Bisogno T,Fratta W,Fadda P

更新日期：2018-02-02 00:00:00

abstract：:Compelling data demonstrate that inflammation-associated anorexia directly results from the action of pro-inflammatory factors, primarily cytokines and prostaglandins E2, on the nervous system. For instance, the aforementioned pro-inflammatory factors can stimulate the activity of peripheral sensory neurons, and induc...

journal_title：Frontiers in neuroscience

authors： Gautron L,Layé S

更新日期：2010-01-08 00:00:00

abstract：:On a large sample of 2288 Han Chinese undergraduates, we investigated how religion and DRD4 are related to human altruistic giving behavior as measured with the Andreoni-Miller Dictator Game. This game enables us to clearly specify (non-)selfishness, efficiency, and fairness motives for sharing. Participants were furt...

journal_title：Frontiers in neuroscience

authors： Jiang Y,Bachner-Melman R,Chew SH,Ebstein RP

更新日期：2015-09-24 00:00:00

abstract：Background:Individuals are able to perform goal-directed behaviors thanks to executive functions. According to the neurovisceral integration model, executive functions are upregulated by brain areas such as the prefrontal and cingulate cortices, which are also crucially involved in controlling cardiac vagal activity. A...

journal_title：Frontiers in neuroscience

authors： Borges U,Knops L,Laborde S,Klatt S,Raab M

更新日期：2020-05-25 00:00:00

abstract：:Cochlear implantation constitutes a successful therapy of inner ear deafness, with the majority of patients showing good outcomes. There is, however, still some unexplained variability in outcomes with a number of cochlear-implant (CI) users, showing major limitations in speech comprehension. The current study used a ...

journal_title：Frontiers in neuroscience

authors： Kessler M,Schierholz I,Mamach M,Wilke F,Hahne A,Büchner A,Geworski L,Bengel FM,Sandmann P,Berding G

更新日期：2020-08-11 00:00:00

abstract：:The efficacy of neuronal function requires a well-balanced extracellular ion homeostasis and a steady supply with nutrients and metabolites. Therefore, all organisms equipped with a complex nervous system developed a so-called blood-brain barrier, protecting it from an uncontrolled entry of solutes, metabolites or pat...

journal_title：Frontiers in neuroscience

authors： Limmer S,Weiler A,Volkenhoff A,Babatz F,Klämbt C

更新日期：2014-11-14 00:00:00

abstract：:Perinatal asphyxia (PA) is a clinical condition brought by a birth temporary oxygen deprivation associated with long-term damage in the corpus striatum, one of the most compromised brain areas. Palmitoylethanolamide (PEA) is a neuromodulator well known for its protective effects in brain injury models, including PA, a...

journal_title：Frontiers in neuroscience

authors： Udovin LD,Kobiec T,Herrera MI,Toro-Urrego N,Kusnier CF,Kölliker-Frers RA,Ramos-Hryb AB,Luaces JP,Otero-Losada M,Capani F

更新日期：2020-01-08 00:00:00

abstract：:The bladder is innervated by extrinsic afferents that project into the dorsal horn of the spinal cord, providing sensory input to the micturition centers within the central nervous system. Under normal conditions, the continuous activation of these neurons during bladder distension goes mostly unnoticed. However, for ...

journal_title：Frontiers in neuroscience

authors： Grundy L,Caldwell A,Brierley SM

更新日期：2018-12-12 00:00:00

abstract：:Event-related potentials (ERPs) are often used in brain-computer interfaces (BCIs) for communication or system control for enhancing or regaining control for motor-disabled persons. Especially results from single-trial EEG classification approaches for BCIs support correlations between single-trial ERP detection perfo...

journal_title：Frontiers in neuroscience

authors： Kirchner EA,Kim SK

更新日期：2018-03-27 00:00:00

abstract：:Artificial neural networks (ANNs) trained using backpropagation are powerful learning architectures that have achieved state-of-the-art performance in various benchmarks. Significant effort has been devoted to developing custom silicon devices to accelerate inference in ANNs. Accelerating the training phase, however, ...

journal_title：Frontiers in neuroscience

authors： Mostafa H,Pedroni B,Sheik S,Cauwenberghs G

更新日期：2017-09-06 00:00:00

abstract：Objective:To evaluate the effects of long-term High-definition transcranial direct current stimulation (HD-tDCS) over precuneus on the level of consciousness (LOC) and the relationship between Mismatch negativity (MMN) and the LOC over the therapy period in patients with Disorders of consciousness (DOCs). Methods:We e...

journal_title：Frontiers in neuroscience

authors： Wang X,Guo Y,Zhang Y,Li J,Gao Z,Li Y,Zhou T,Zhang H,He J,Cong F

更新日期：2020-04-28 00:00:00

abstract：:Although the genetic basis of Tourette Syndrome (TS) remains unclear, several candidate genes have been implicated. Using a set of 382 TS individuals of European ancestry we investigated four candidate genes for TS (HDC, SLITRK1, BTBD9, and SLC6A4) in an effort to identify possibly causal variants using a targeted re-...

journal_title：Frontiers in neuroscience

authors： Alexander J,Potamianou H,Xing J,Deng L,Karagiannidis I,Tsetsos F,Drineas P,Tarnok Z,Rizzo R,Wolanczyk T,Farkas L,Nagy P,Szymanska U,Androutsos C,Tsironi V,Koumoula A,Barta C,TSGeneSEE.,Sandor P,Barr CL,Tischfield

更新日期：2016-09-21 00:00:00

abstract：:Gene expression profiling was performed on the human neuroglial cell line T98G after treatment with adaptogen ADAPT-232 and its constituents - extracts of Eleutherococcus senticosus root, Schisandra chinensis berry, and Rhodiola rosea root as well as several constituents individually, namely, eleutheroside E, schizand...

journal_title：Frontiers in neuroscience

authors： Panossian A,Hamm R,Kadioglu O,Wikman G,Efferth T

更新日期：2013-02-20 00:00:00

abstract：:The combination of electromyography (EMG) and transcranial magnetic stimulation (TMS) offers a powerful non-invasive approach for investigating corticospinal excitability in both humans and animals. Acquiring and analyzing the data produced with this combination of tools requires overcoming multiple technical hurdles....

journal_title：Frontiers in neuroscience

authors： Jackson N,Greenhouse I

更新日期：2019-09-13 00:00:00

abstract：:The walking mechanism of a prosthetic leg user is a tightly coordinated movement of several joints and limb segments. The interaction among the voluntary and mechanical joints and segments requires particular biomechanical insight. This study aims to analyze the inter-relationship between amputees' voluntary and mecha...

journal_title：Frontiers in neuroscience

authors： Jasni F,Hamzaid NA,Mohd Syah NE,Chung TY,Abu Osman NA

更新日期：2017-04-25 00:00:00

abstract：Background:Cranial irradiation is a common therapy for the treatment of brain tumors, but unfortunately patients suffer from side effects, particularly cognitive impairment, caused by neurodegenerative and neuroinflammatory mechanisms. Finding a therapeutic agent protecting hippocampal neurons would be beneficial. Fing...

journal_title：Frontiers in neuroscience

authors： Metzdorf J,Hobloss Z,Schlevogt S,Ayzenberg I,Stahlke S,Pedreiturria X,Haupeltshofer S,Gold R,Tönges L,Kleiter I

更新日期：2019-07-09 00:00:00

abstract：:Over the past several decades, clinical studies have shown significant analgesic effects of acupuncture. The efficacy of acupuncture treatment has improved with the recent development of nanoporous needles (PN), which are produced by modifying the needle surface using nanotechnology. Herein, we showed that PN at acupo...

journal_title：Frontiers in neuroscience

authors： Bae SJ,Lim J,Lee S,Choi H,Jang JH,Kim YK,Oh JY,Park JH,Jung HS,Chae Y,In SI,Park HJ

更新日期：2019-06-20 00:00:00

abstract：:Amyotrophic lateral sclerosis (ALS) is a fatal adult-onset neurodegenerative disorder affecting motor neurons (MNs). Evidences indicate that ALS is a non-cell autonomous disease in which glial cells participate in both disease onset and progression. Exosomal transfer of mutant copper-zinc superoxide dismutase 1 (mSOD1...

journal_title：Frontiers in neuroscience

authors： Pinto S,Cunha C,Barbosa M,Vaz AR,Brites D

更新日期：2017-05-17 00:00:00

abstract：:The diagnosis of multiple sclerosis (MS) is usually based on clinical symptoms and signs of damage to the central nervous system, which is assessed using magnetic resonance imaging. The correct interpretation of these data requires excellent clinical expertise and experience. Deep neural networks aim to assist clinici...

journal_title：Frontiers in neuroscience

authors： Lopatina A,Ropele S,Sibgatulin R,Reichenbach JR,Güllmar D

更新日期：2020-12-18 00:00:00

abstract：BACKGROUND:Cortical modulation is likely to be involved in the various therapeutic effects of deep brain stimulation (DBS). However, it is currently difficult to predict the changes of cortical modulation during clinical adjustment of DBS. Therefore, we present a novel quantitative approach to estimate anatomical regio...

journal_title：Frontiers in neuroscience

authors： Hartmann CJ,Chaturvedi A,Lujan JL

更新日期：2015-02-10 00:00:00

abstract：:Previous research has provided qualitative evidence for overlap in a number of brain regions across the subjective value network (SVN) and the default mode network (DMN). In order to quantitatively assess this overlap, we conducted a series of coordinate-based meta-analyses (CBMA) of results from 466 functional magnet...

journal_title：Frontiers in neuroscience

authors： Acikalin MY,Gorgolewski KJ,Poldrack RA

更新日期：2017-01-19 00:00:00

abstract：:Understanding the effects of environmental stimulation in autism can improve therapeutic interventions against debilitating sensory overload, social withdrawal, fear and anxiety. Here, we evaluate the role of environmental predictability on behavior and protein expression, and inter-individual differences, in the valp...

journal_title：Frontiers in neuroscience

authors： Favre MR,La Mendola D,Meystre J,Christodoulou D,Cochrane MJ,Markram H,Markram K

更新日期：2015-06-02 00:00:00

abstract：:The aim of the present study was to test whether transcranial electrical stimulation can modulate illusory perception in the auditory domain. In two separate experiments we applied transcranial Direct Current Stimulation (anodal/cathodal tDCS, 2 mA; N = 60) and high-frequency transcranial Random Noise Stimulation (hf-...

journal_title：Frontiers in neuroscience

authors： Prete G,D'Anselmo A,Tommasi L,Brancucci A

更新日期：2017-06-20 00:00:00

abstract：:Spinal cord injury (SCI), one of the most severe types of neurological damage, results in persistent motor and sensory dysfunction and involves complex gene alterations. Circular RNAs (circRNAs) are a recently discovered class of regulatory molecules, and their roles in SCI still need to be addressed. This study compr...

journal_title：Frontiers in neuroscience

authors： Wu R,Mao S,Wang Y,Zhou S,Liu Y,Liu M,Gu X,Yu B

更新日期：2019-12-10 00:00:00

abstract：:Frontotemporal Dementia (FTD) is a focal neurodegenerative disease, with a strong genetic background, that causes early onset dementia. The present knowledge about the risk loci and causative mutations of FTD mainly derives from genetic linkage analysis, studies of candidate genes, Genome-Wide Association Studies (GWA...

journal_title：Frontiers in neuroscience

authors： Ciani M,Benussi L,Bonvicini C,Ghidoni R

更新日期：2019-05-16 00:00:00

abstract：:The GABAergic neurons in the lateral pontine tegmentum (LPT) play key roles in the regulation of sleep and locomotion. The dysfunction of the LPT is related to neurological disorders such as rapid eye movement sleep behavior disorder and ocular flutter. However, the whole-brain neural connectivity to LPT GABAergic neu...

journal_title：Frontiers in neuroscience

authors： Chen ZK,Yuan XS,Dong H,Wu YF,Chen GH,He M,Qu WM,Huang ZL

更新日期：2019-04-24 00:00:00

abstract：:In adult mammals, neural stem cells (NSCs) are found in two niches of the brain; the subventricular zone by the lateral ventricles and the subgranular zone of the dentate gyrus in the hippocampus. Neurogenesis is a complex process that is tightly controlled on a molecular level. Recently, microRNAs (miRNAs) have been ...

journal_title：Frontiers in neuroscience

authors： Akerblom M,Sachdeva R,Jakobsson J

更新日期：2012-02-07 00:00:00

abstract：Introduction:Low back pain (LBP) is a complex and growing global health problem in need of more effective pain management strategies. Spinal mobilization (SM) is a non-pharmacological approach recommended by most clinical guidelines for LBP, but greater utilization and treatment optimization are hampered by a lack of m...

journal_title：Frontiers in neuroscience

authors： Reed WR,Little JW,Lima CR,Sorge RE,Yarar-Fisher C,Eraslan M,Hurt CP,Ness TJ,Gu JG,Martins DF,Li P

更新日期：2020-04-30 00:00:00