Auditory Perceptual Learning for Speech Perception Can be Enhanced by Audiovisual Training.

abstract：BACKGROUND:Cortical modulation is likely to be involved in the various therapeutic effects of deep brain stimulation (DBS). However, it is currently difficult to predict the changes of cortical modulation during clinical adjustment of DBS. Therefore, we present a novel quantitative approach to estimate anatomical regio...

journal_title：Frontiers in neuroscience

authors： Hartmann CJ,Chaturvedi A,Lujan JL

更新日期：2015-02-10 00:00:00

abstract：:The role of mitochondria within injured neurons is an area of active interest since these organelles are vital for the production of cellular energy in the form of ATP. Using mechanosensory neurons of the nematode Caenorhabditis elegans to test regeneration after neuronal injury in vivo, we surveyed genes related to m...

journal_title：Frontiers in neuroscience

authors： Knowlton WM,Hubert T,Wu Z,Chisholm AD,Jin Y

更新日期：2017-05-10 00:00:00

abstract：:Chemical communication via sex pheromones is critical for successful reproduction but the underlying neural mechanisms are not well-understood. The goldfish is a tractable model because sex pheromones have been well-characterized in this species. We used male goldfish forebrain explants in vitro and performed whole-ce...

journal_title：Frontiers in neuroscience

authors： Lado WE,Spanswick DC,Lewis JE,Trudeau VL

更新日期：2014-06-30 00:00:00

abstract：:Central pattern generator (CPG) networks coordinate the generation of rhythmic activity such as locomotion and respiration. Their development is driven by various transcription factors, one of which is the Wilms tumor protein (Wt1). It is present in dI6 neurons of the mouse spinal cord, and involved in the coordinatio...

journal_title：Frontiers in neuroscience

authors： Schnerwitzki D,Hayn C,Perner B,Englert C

更新日期：2020-11-30 00:00:00

abstract：:Aging is a complex natural phenomenon that is manifested by degenerative changes in the structure and function of cells and tissues. D-Galactose-induced aging mice are an artificial accelerated aging model that causes memory and learning impairment, oxidative stress, and neuroinflammation. In this study, we examined t...

journal_title：Frontiers in neuroscience

authors： Li H,Zheng L,Chen C,Liu X,Zhang W

更新日期：2019-09-18 00:00:00

abstract：:ATP is released in an activity-dependent manner from different cell types in the brain, fulfilling different roles as a neurotransmitter, neuromodulator, in astrocyte-to-neuron communication, propagating astrocytic responses and formatting microglia responses. This involves the activation of different ATP P2 receptors...

journal_title：Frontiers in neuroscience

authors： Rodrigues RJ,Tomé AR,Cunha RA

更新日期：2015-04-28 00:00:00

abstract：:α-Synuclein is a 140-amino acid protein that readily misfolds and is associated with the Lewy body pathology found in sporadic and genetic forms of Parkinson's disease. We and others have shown that wild-type α-synuclein is a damage-associated molecular pattern that directly elicits a proinflammatory response in micro...

journal_title：Frontiers in neuroscience

authors： Sánchez K,Maguire-Zeiss K

更新日期：2020-12-02 00:00:00

abstract：:We performed this study to investigate the possibility of a definitive pattern of Galectin-3 (Gal-3) expression in the cerebrospinal fluid (CSF) and serum of Alzheimer's disease (AD) and Amyotrophic Lateral Sclerosis (ALS) patients. In our study, we collected the CSF and serum samples of 31 AD patients, 19 ALS patient...

journal_title：Frontiers in neuroscience

authors： Ashraf GM,Baeesa SS

更新日期：2018-06-29 00:00:00

abstract：:The neural generators of the frequency-following response (FFR), a neural response widely used to study the human auditory system, remain unclear. There is evidence that the balance between cortical and subcortical contributions to the FFR varies with stimulus frequency. In this study, we tried to clarify whether this...

journal_title：Frontiers in neuroscience

authors： Zhang X,Gong Q

更新日期：2019-02-26 00:00:00

abstract：:Inhibitory control, the ability to suppress an immediate dominant response, has been shown to predict academic and career success, socioemotional wellbeing, wealth, and physical health. Learning to play a musical instrument engages various sensorimotor processes and draws on cognitive capacities including inhibition a...

journal_title：Frontiers in neuroscience

authors： Hennessy SL,Sachs ME,Ilari B,Habibi A

更新日期：2019-10-16 00:00:00

abstract：:The diagnosis of multiple sclerosis (MS) is usually based on clinical symptoms and signs of damage to the central nervous system, which is assessed using magnetic resonance imaging. The correct interpretation of these data requires excellent clinical expertise and experience. Deep neural networks aim to assist clinici...

journal_title：Frontiers in neuroscience

authors： Lopatina A,Ropele S,Sibgatulin R,Reichenbach JR,Güllmar D

更新日期：2020-12-18 00:00:00

abstract：:The increasing rate of age-related hearing loss (ARHL), with its subsequent reduction in quality of life and increase in health care costs, requires new therapeutic strategies to reduce and delay its impact. The goal of this study was to determine if ARHL could be reduced in a rat model by administering a combination ...

journal_title：Frontiers in neuroscience

authors： Alvarado JC,Fuentes-Santamaría V,Gabaldón-Ull MC,Juiz JM

更新日期：2018-07-31 00:00:00

abstract：:Astrocytes are the most abundant type of glial cell in the central nervous system and perform a myriad of vital functions, however, the nature of their diversity remains a longstanding question in neuroscience. Using transcription factor motif discovery analysis on region-specific gene signatures from astrocytes we un...

journal_title：Frontiers in neuroscience

authors： Lozzi B,Huang TW,Sardar D,Huang AY,Deneen B

更新日期：2020-02-21 00:00:00

abstract：:Changes in cerebral blood flow (CBF) during a hyperglycemic challenge were mapped, using perfusion-weighted MRI, in a group of non-human primates. Seven female baboons were fasted for 16 h prior to 1-h imaging experiment, performed under general anesthesia, that consisted of a 20-min baseline, followed by a bolus infu...

journal_title：Frontiers in neuroscience

authors： Kochunov P,Wey HY,Fox PT,Lancaster JL,Davis MD,Wang DJ,Lin AL,Bastarrachea RA,Andrade MC,Mattern V,Frost P,Higgins PB,Comuzzie AG,Voruganti VS

更新日期：2017-02-14 00:00:00

abstract：:Probability and risk are important factors for value-based decision making and optimal foraging. In order to survive in an unpredictable world, organisms must be able to assess the probability and risk attached to future events and use this information to generate adaptive behavior. Recent studies in non-human primate...

journal_title：Frontiers in neuroscience

authors： Burke CJ,Tobler PN

更新日期：2011-10-11 00:00:00

abstract：:In the present review, we deliver an overview of the involvement of metabotropic glutamate receptor 5 (mGluR5) activity and density in pathological anxiety, mood disorders and addiction. Specifically, we will describe mGluR5 studies in humans that employed Positron Emission Tomography (PET) and combined the findings w...

journal_title：Frontiers in neuroscience

authors： Terbeck S,Akkus F,Chesterman LP,Hasler G

更新日期：2015-03-18 00:00:00

abstract：:Alzheimer's disease (AD) is a progressive brain disorder with gradual memory loss that correlates to cognitive deficits in the elderly population. Recent studies have shown the potentials of machine learning algorithms to identify biomarkers and functional brain activity patterns across various AD stages using electro...

journal_title：Frontiers in neuroscience

authors： Fan M,Yang AC,Fuh JL,Chou CA

更新日期：2018-10-04 00:00:00

abstract：:Recently, Parkinson's disease-associated α-synuclein (αS) has emerged as an important regulator for SNARE-dependent vesicle fusion. However, it is controversial if excessive accumulation of αS, even in the absence of aggregation, impairs neurotransmission. Here we use a single vesicle fusion assay with ms time resolut...

journal_title：Frontiers in neuroscience

authors： Hawk BJD,Khounlo R,Shin YK

更新日期：2019-03-21 00:00:00

abstract：:A growing body of work underlines striking similarities between biological neural networks and recurrent, binary neural networks. A relatively smaller body of work, however, addresses the similarities between learning dynamics employed in deep artificial neural networks and synaptic plasticity in spiking neural networ...

journal_title：Frontiers in neuroscience

authors： Kaiser J,Mostafa H,Neftci E

更新日期：2020-05-12 00:00:00

abstract：:Graph neural networks (GNN) rely on graph operations that include neural network training for various graph related tasks. Recently, several attempts have been made to apply the GNNs to functional magnetic resonance image (fMRI) data. Despite recent progresses, a common limitation is its difficulty to explain the clas...

journal_title：Frontiers in neuroscience

authors： Kim BH,Ye JC

更新日期：2020-06-30 00:00:00

abstract：:The Ossification of the Posterior Longitudinal Ligament (OPLL) is an idiopathic degenerative spinal disease which may cause motor deficit. For patients presenting myelopathy or severe stenosis, surgical decompression is the treatment of choice; however, despite adequate decompression residual motor impairment is found...

journal_title：Frontiers in neuroscience

authors： Puentes S,Kadone H,Kubota S,Abe T,Shimizu Y,Marushima A,Sankai Y,Yamazaki M,Suzuki K

更新日期：2018-03-02 00:00:00

abstract：:ROCK inhibition has been largely applied as a strategy to treat neurodegenerative diseases (NDDs) and promising results have been obtained in the recent years. However, the underlying molecular and cellular mechanisms are not fully understood and different models have been proposed for neurodegenerative disorders. Her...

journal_title：Frontiers in neuroscience

authors： Hensel N,Rademacher S,Claus P

更新日期：2015-06-02 00:00:00

abstract：:We asked whether coordinated voluntary movement of the lower limbs could be regained in an individual having been completely paralyzed (>4 year) and completely absent of vision (>15 year) using two novel strategies-transcutaneous electrical spinal cord stimulation at selected sites over the spine as well as pharmacolo...

journal_title：Frontiers in neuroscience

authors： Gad P,Gerasimenko Y,Zdunowski S,Turner A,Sayenko D,Lu DC,Edgerton VR

更新日期：2017-06-08 00:00:00

abstract：:Brain state classification for communication and control has been well established in the area of brain-computer interfaces over the last decades. Recently, the passive and automatic extraction of additional information regarding the psychological state of users from neurophysiological signals has gained increased att...

journal_title：Frontiers in neuroscience

authors： Hettich DT,Bolinger E,Matuz T,Birbaumer N,Rosenstiel W,Spüler M

更新日期：2016-06-10 00:00:00

abstract：:Recent studies suggest cone degeneration in retinitis pigmentosa (RP) may result from intracellular energy depletion. We tested the hypothesis that cones die when depleted of energy by examining the effect of two bioenergetic, nutraceutical agents on cone survival. The study had three specific aims: firstly, we, studi...

journal_title：Frontiers in neuroscience

authors： Narayan DS,Chidlow G,Wood JPM,Casson RJ

更新日期：2019-11-15 00:00:00

abstract：:Intracerebral hemorrhage (ICH) is a major type of cerebrovascular disease with poor prognosis. Recent studies have shown that Glycyl-l-histidyl-l-lysine (GHK) is a kind of natural human tripeptide which could inhibit inflammation and against neurodegenerative diseases, but neither its role nor the mechanisms in ICH ha...

journal_title：Frontiers in neuroscience

authors： Zhang H,Wang Y,Lian L,Zhang C,He Z

更新日期：2020-10-28 00:00:00

abstract：:Donepezil is a potent acetylcholinesterase inhibitor, largely used worldwide to alleviate cognitive symptoms in Alzheimer's disease (AD). Beyond the widely described neuronal impact of donepezil, it was recently shown that targeting connexins, the proteins involved in astrocyte network organization, potentiates donepe...

journal_title：Frontiers in neuroscience

authors： Vidal B,Droguerre M,Valdebenito M,Zimmer L,Hamon M,Mouthon F,Charvériat M

更新日期：2020-08-12 00:00:00

abstract：:We investigated whether the C9orf72 repeat expansion is associated with specific clinical features, comorbidities, and prognosis in patients with amyotrophic lateral sclerosis (ALS). A cohort of 1417 ALS patients, diagnosed between January 1, 2009 and December 31, 2013 by 13 Italian ALS Referral Centers, was screened ...

journal_title：Frontiers in neuroscience

authors： Trojsi F,Siciliano M,Femiano C,Santangelo G,Lunetta C,Calvo A,Moglia C,Marinou K,Ticozzi N,Ferro C,Scialò C,Sorarù G,Conte A,Falzone YM,Tortelli R,Russo M,Sansone VA,Chiò A,Mora G,Silani V,Volanti P,Caponnetto C

更新日期：2019-05-17 00:00:00

abstract：:The dentate gyrus (DG) is a region in the mammalian brain critical for memory encoding with a neuronal architecture and function that deviates considerably from other cortical areas. One of the major differences of the DG compared to other brain regions is the finding that the dentate gyrus generates new principal neu...

journal_title：Frontiers in neuroscience

authors： Piatti VC,Ewell LA,Leutgeb JK

更新日期：2013-04-04 00:00:00

abstract：:Numerous observational studies have shown that depressive symptoms are common in individuals with mild cognitive impairment (MCI) who have a higher rate of progress to dementia. However, it is still uncertain whether there are any differences between MCI patients with and without depression symptom in their brain func...

journal_title：Frontiers in neuroscience

authors： Yu Y,Li Z,Lin Y,Yu J,Peng G,Zhang K,Jia X,Luo B

更新日期：2019-12-17 00:00:00