RAPA-ConvNets: Modified Convolutional Networks for Accelerated Training on Architectures With Analog Arrays.

abstract：:Recent intriguing evidence suggests that metabolites of amyloid precursor protein (APP), mutated in familial forms of Alzheimer's disease (AD), play critical roles in developmental and postnatal neurogenesis. Of note is soluble APPα (sAPPα) that regulates neural progenitor cell proliferation. The APP family encompasse...

journal_title：Frontiers in neuroscience

authors： Lazarov O,Demars MP

更新日期：2012-06-04 00:00:00

abstract：:Glutamate-induced excitotoxicity is one of the main causes of neuronal cell death in stroke. Compound 22a has been previously reported as a promising neuroprotective compound derived from tetramethylpyrazine, which is a widely used active ingredient of traditional Chinese medicine Chuanxiong (Ligusticum wallichii Fran...

journal_title：Frontiers in neuroscience

authors： Chen H,Cao J,Zhu Z,Zhang G,Shan L,Yu P,Wang Y,Sun Y,Zhang Z

更新日期：2018-08-15 00:00:00

abstract：:Head motion is one of major concerns in current resting-state functional MRI studies. Image realignment including motion estimation and spatial resampling is often applied to achieve rigid-body motion correction. While the accurate estimation of motion parameters has been addressed in most studies, spatial resampling ...

journal_title：Frontiers in neuroscience

authors： Yuan L,He H,Zhang H,Zhong J

更新日期：2016-12-27 00:00:00

abstract：:Self-control exertion on an initial task has been associated with impaired performance on subsequent physical tasks also requiring self-control; an effect suggested to be mediated by changes in perceptions of pain and motivation. However, the effects of spending longer on the initial self-control task are unknown. Thi...

journal_title：Frontiers in neuroscience

authors： Boat R,Hunte R,Welsh E,Dunn A,Treadwell E,Cooper SB

更新日期：2020-10-08 00:00:00

abstract：:Central pattern generator (CPG) networks coordinate the generation of rhythmic activity such as locomotion and respiration. Their development is driven by various transcription factors, one of which is the Wilms tumor protein (Wt1). It is present in dI6 neurons of the mouse spinal cord, and involved in the coordinatio...

journal_title：Frontiers in neuroscience

authors： Schnerwitzki D,Hayn C,Perner B,Englert C

更新日期：2020-11-30 00:00:00

abstract：:Psychosis has been considered a disorder of impaired neuronal connectivity. Evidence for excessive formation of dopamine D2 receptor (D2R) - disrupted in schizophrenia 1 (DISC1) complexes has led to a new perspective on molecular mechanisms involved in psychotic symptoms. Here, we investigated how excessive D2R-DISC1 ...

journal_title：Frontiers in neuroscience

authors： Zheng P,Su QP,Jin D,Yu Y,Huang XF

更新日期：2020-06-23 00:00:00

abstract：:Protein tyrosine phosphatases (PTPs) are important regulators of intracellular signaling pathways via the dephosphorylation of phosphotyrosyl residues on various receptor and non-receptor substrates. The phosphorylation state of central nervous system (CNS) signaling components underlies the molecular mechanisms of a ...

journal_title：Frontiers in neuroscience

authors： Tsou RC,Bence KK

更新日期：2013-01-07 00:00:00

abstract：:The linearity and stationarity of fMRI time series need to be understood due to their important roles in the choice of approach for brain network analysis. In this paper, we investigated the stationarity and linearity of resting-state fMRI (rs-fMRI) time-series data from the Midnight Scan Club datasets. The degree of ...

journal_title：Frontiers in neuroscience

authors： Guan S,Jiang R,Bian H,Yuan J,Xu P,Meng C,Biswal B

更新日期：2020-06-11 00:00:00

abstract：:SpiNNaker is a digital neuromorphic architecture, designed specifically for the low power simulation of large-scale spiking neural networks at speeds close to biological real-time. Unlike other neuromorphic systems, SpiNNaker allows users to develop their own neuron and synapse models as well as specify arbitrary conn...

journal_title：Frontiers in neuroscience

authors： Mikaitis M,Pineda García G,Knight JC,Furber SB

更新日期：2018-02-27 00:00:00

abstract：:Disruption of iron homeostasis and increased glial response are known to occur in brains afflicted by Alzheimer's disease (AD). While the APP/PS1 transgenic mouse model recapitulates the hallmark amyloid-beta plaque pathology of AD, it does so in a different neuronal mileu than humans. Understanding the iron character...

journal_title：Frontiers in neuroscience

authors： Meadowcroft MD,Connor JR,Yang QX

更新日期：2015-07-23 00:00:00

abstract：:Recent increases in attention deficit hyperactivity disorder (ADHD) diagnoses, and the escalation of stimulant prescriptions, has raised concern about diversion and abuse of stimulants, as well as the ethics of using these drugs as "cognitive enhancers."Such concern appears misplaced in the face of substantial evidenc...

journal_title：Frontiers in neuroscience

authors： Advokat C,Scheithauer M

更新日期：2013-05-29 00:00:00

abstract：Background:Early exposure to nociceptive events may cause brain structural alterations in preterm neonates, with long-lasting consequences on neurodevelopmental outcome. Little is known on the extent to which early pain may affect brain connectivity. We aim to evaluate brain functional connectivity changes in preterm n...

journal_title：Frontiers in neuroscience

authors： Tortora D,Severino M,Di Biase C,Malova M,Parodi A,Minghetti D,Traggiai C,Uccella S,Boeri L,Morana G,Rossi A,Ramenghi LA

更新日期：2019-08-23 00:00:00

abstract：:The neuropeptide oxytocin plays a central role in prosocial and parental behavior in non-human mammals as well as humans. It has been suggested that oxytocin may affect visual processing of infant faces and emotional reaction to infants. Healthy male volunteers (N = 13) were tested for their ability to detect infant o...

journal_title：Frontiers in neuroscience

authors： Saito A,Hamada H,Kikusui T,Mogi K,Nagasawa M,Mitsui S,Higuchi T,Hasegawa T,Hiraki K

更新日期：2014-07-29 00:00:00

abstract：:Dynamic Field Theory (DFT) is an established framework for modeling embodied cognition. In DFT, elementary cognitive functions such as memory formation, formation of grounded representations, attentional processes, decision making, adaptation, and learning emerge from neuronal dynamics. The basic computational element...

journal_title：Frontiers in neuroscience

authors： Sandamirskaya Y

更新日期：2014-01-22 00:00:00

abstract：:Throughout development, neural stem cells (NSCs) give rise to differentiated neurons, astrocytes, and oligodendrocytes which together modulate perception, memory, and behavior in the adult nervous system. To understand how NSCs contribute to postnatal/adult brain remodeling and repair after injury, the lateral ventric...

journal_title：Frontiers in neuroscience

authors： Adlaf EW,Mitchell-Dick A,Kuo CT

更新日期：2016-03-24 00:00:00

abstract：:Traumatic brain injury (TBI) is a major public health concern that affects 69 million individuals each year worldwide. Neuropsychologists report that up to 40% of individuals undergoing evaluations for TBI may be malingering neurocognitive deficits for a compensatory reward. The memory recognition test of malingering ...

journal_title：Frontiers in neuroscience

authors： Neal J,Strothkamp S,Bedingar E,Cordero P,Wagner B,Vagnini V,Jiang Y

更新日期：2019-09-25 00:00:00

abstract：:This paper developed a cognitive task-load (CTL) classification algorithm and allocation strategy to sustain the optimal operator CTL levels over time in safety-critical human-machine integrated systems. An adaptive human-machine system is designed based on a non-linear dynamic CTL classifier, which maps a set of elec...

journal_title：Frontiers in neuroscience

authors： Zhang J,Yin Z,Wang R

更新日期：2017-03-17 00:00:00

abstract：:Donepezil is a potent acetylcholinesterase inhibitor, largely used worldwide to alleviate cognitive symptoms in Alzheimer's disease (AD). Beyond the widely described neuronal impact of donepezil, it was recently shown that targeting connexins, the proteins involved in astrocyte network organization, potentiates donepe...

journal_title：Frontiers in neuroscience

authors： Vidal B,Droguerre M,Valdebenito M,Zimmer L,Hamon M,Mouthon F,Charvériat M

更新日期：2020-08-12 00:00:00

abstract：:Value-based decision making relies on distributed neural systems that weigh the benefits of actions against the cost required to obtain a given outcome. Perturbations of these systems are thought to underlie abnormalities in action selection seen across many neuropsychiatric disorders. Genetic tools in mice provide a ...

journal_title：Frontiers in neuroscience

authors： Alabi OO,Fortunato MP,Fuccillo MV

更新日期：2019-02-07 00:00:00

abstract：:State-of-the-art large-scale neuromorphic systems require sophisticated spike event communication between units of the neural network. We present a high-speed communication infrastructure for a waferscale neuromorphic system, based on application-specific neuromorphic communication ICs in an field programmable gate ar...

journal_title：Frontiers in neuroscience

authors： Scholze S,Schiefer S,Partzsch J,Hartmann S,Mayr CG,Höppner S,Eisenreich H,Henker S,Vogginger B,Schüffny R

更新日期：2011-10-12 00:00:00

abstract：:The analysis of spontaneous functional connectivity (sFC) reveals the statistical connections between regions of the brain consistent with underlying functional communication networks within the brain. In this work, we describe the implementation of a complete all-to-all network analysis of resting state neuronal acti...

journal_title：Frontiers in neuroscience

authors： Schmidt BT,Ghuman AS,Huppert TJ

更新日期：2014-06-11 00:00:00

abstract：:The hippocampus has exhibited navigation-related changes in volume and activity after visual deprivation; however, the resting-state functional connectivity (rsFC) changes of the hippocampus in the blind remains unknown. In this study, we focused on sub-region-specific rsFC changes of the hippocampus and their associa...

journal_title：Frontiers in neuroscience

authors： Ma G,Yang D,Qin W,Liu Y,Jiang T,Yu C

更新日期：2017-01-10 00:00:00

abstract：:Recently, Parkinson's disease-associated α-synuclein (αS) has emerged as an important regulator for SNARE-dependent vesicle fusion. However, it is controversial if excessive accumulation of αS, even in the absence of aggregation, impairs neurotransmission. Here we use a single vesicle fusion assay with ms time resolut...

journal_title：Frontiers in neuroscience

authors： Hawk BJD,Khounlo R,Shin YK

更新日期：2019-03-21 00:00:00

abstract：:Recent studies have identified the Drosophila brain circuits involved in the sleep/wake switch and have pointed to the modulation of neuronal excitability as one of the underlying mechanisms triggering sleep need. In this study we aimed to explore the link between the homeostatic regulation of neuronal excitability an...

journal_title：Frontiers in neuroscience

authors： De Jesús-Olmo LA,Rodríguez N,Francia M,Alemán-Rios J,Pacheco-Agosto CJ,Ortega-Torres J,Nieves R,Fuenzalida-Uribe N,Ghezzi A,Agosto JL

更新日期：2020-04-17 00:00:00

abstract：:Perception is an active process that interprets and structures the stimulus input based on assumptions about its possible causes. We use real-time functional magnetic resonance imaging (rtfMRI) to investigate a particularly powerful demonstration of dynamic object integration in which the same physical stimulus interm...

journal_title：Frontiers in neuroscience

authors： Reichert C,Fendrich R,Bernarding J,Tempelmann C,Hinrichs H,Rieger JW

更新日期：2014-05-23 00:00:00

abstract：:Obesity is known to induce leptin and insulin resistance. Leptin is a peptide hormone synthesized in adipose tissue that mainly regulates food intake. It has been shown that insulin stimulates the production of leptin when adipocytes are exposed to glucose to encourage satiety; while leptin, via a negative feedback, d...

journal_title：Frontiers in neuroscience

authors： Lloret A,Monllor P,Esteve D,Cervera-Ferri A,Lloret MA

更新日期：2019-05-22 00:00:00

abstract：:Oxylipins are a series of bioactive lipid metabolites derived from polyunsaturated fatty acids that are involved in cerebral homeostasis and the development of intracerebral hemorrhage (ICH). However, comprehensive quantification of the oxylipin profile in ICH remains unknown. Therefore, an ICH mouse model was constru...

journal_title：Frontiers in neuroscience

authors： Yuan JJ,Chen Q,Xiong XY,Zhang Q,Xie Q,Huang JC,Yang GQ,Gong CX,Qiu ZM,Sang HF,Zi WJ,He Q,Xu R,Yang QW

更新日期：2020-09-23 00:00:00

abstract：:The cardiovascular and respiratory effects of exercise have been widely studied, as have the autonomic effects of imagined and observed exercise. However, the effects of observed exercise in the first person have not been documented, nor have direct recordings of muscle sympathetic nerve activity (MSNA) been obtained ...

journal_title：Frontiers in neuroscience

authors： Brown R,Kemp U,Macefield V

更新日期：2013-06-11 00:00:00

abstract：:Cryptotanshinone (CTN), a monomer compound extracted from the dried roots and rhizomes of Salvia miltiorrhiza Bge, has a variety of pharmacological effects. However, little research has been done on the mechanism of CTN in attenuating neuroinflammation. The present study aimed to investigate whether CTN can ameliorate...

journal_title：Frontiers in neuroscience

authors： Zhou Y,Wang X,Ying W,Wu D,Zhong P

更新日期：2019-08-21 00:00:00

abstract：:Stroke patients with severe motor deficits of the upper extremity may practice rehabilitation exercises with the assistance of a multi-joint exoskeleton. Although this technology enables intensive task-oriented training, it may also lead to slacking when the assistance is too supportive. Preserving the engagement of t...

journal_title：Frontiers in neuroscience

authors： Grimm F,Naros G,Gharabaghi A

更新日期：2016-11-15 00:00:00