Whole brain functional connectivity using phase locking measures of resting state magnetoencephalography.

abstract：:Protein homeostasis (proteostasis) requires the timely degradation of misfolded proteins and their aggregates by protein quality control (PQC), of which molecular chaperones are an essential component. Compared with other cell types, PQC in neurons is particularly challenging because they have a unique cellular struct...

journal_title：Frontiers in neuroscience

authors： Ciechanover A,Kwon YT

更新日期：2017-04-06 00:00:00

abstract：:Motor neurons (MN) degeneration is a main feature of amyotrophic lateral sclerosis (ALS), a neurological disorder with a progressive course. The diagnosis of ALS is essentially a clinical one. Most common symptoms include a gradual neurological deterioration that reflect the impairment and subsequent loss of muscle fu...

journal_title：Frontiers in neuroscience

authors： Forostyak S,Sykova E

更新日期：2017-10-24 00:00:00

abstract：:Increasing evidence suggests that noncoding RNAs play key roles in cellular processes, particularly in the brain. The present study used RNA sequencing to identify the transcriptional landscape of two human neural progenitor cell lines, SK-N-SH and ReNcell CX, as they differentiate into human cortical projection neuro...

journal_title：Frontiers in neuroscience

authors： Hecht PM,Ballesteros-Yanez I,Grepo N,Knowles JA,Campbell DB

更新日期：2015-10-23 00:00:00

abstract：:Information processing in the cerebral cortex requires the activation of diverse neurons across layers and columns, which are established through the coordinated production of distinct neuronal subtypes and their placement along the three-dimensional axis. Over recent years, our knowledge of the regulatory mechanisms ...

journal_title：Frontiers in neuroscience

authors： Toma K,Hanashima C

更新日期：2015-08-11 00:00:00

abstract：:Background: Significant progress toward the recovery of useful vision in blind patients with severe degenerative retinal diseases caused by photoreceptor death has been achieved with the development of visual prostheses that stimulate the retina electrically. However, currently used prostheses do not provide feedback ...

journal_title：Frontiers in neuroscience

authors： Rincón Montes V,Gehlen J,Lück S,Mokwa W,Müller F,Walter P,Offenhäusser A

更新日期：2019-04-30 00:00:00

abstract：:Psychiatric disorders represent a great medical and social challenge and people suffering from these conditions face many impairments regarding personal and professional life. In addition, a mental disorder will manifest itself in approximately one quarter of the world's population at some period of their life. Dysfun...

journal_title：Frontiers in neuroscience

authors： Zuccoli GS,Saia-Cereda VM,Nascimento JM,Martins-de-Souza D

更新日期：2017-09-07 00:00:00

abstract：:The growing interest in intrinsic brain organization has sparked various innovative approaches to generating comprehensive connectivity-based maps of the human brain. Prior reports point to a sexual dimorphism of the structural and functional human connectome. However, it is uncertain whether subtle changes in sex hor...

journal_title：Frontiers in neuroscience

authors： Arélin K,Mueller K,Barth C,Rekkas PV,Kratzsch J,Burmann I,Villringer A,Sacher J

更新日期：2015-02-23 00:00:00

abstract：:To function effectively, brains need to make predictions about their environment based on past experience, i.e., they need to learn about their environment. The algorithms by which learning occurs are of interest to neuroscientists, both in their own right (because they exist in the brain) and as a tool to model parti...

journal_title：Frontiers in neuroscience

authors： O'Reilly JX

更新日期：2013-06-14 00:00:00

abstract：:Hypothalamic neurohormones are released in a pulsatile manner. The mechanisms of this pulsatility remain poorly understood and several hypotheses are available, depending upon the neuroendocrine system considered. Among these systems, hypothalamo-neurohypophyseal magnocellular neurons have been early-considered models...

journal_title：Frontiers in neuroscience

authors： Israel JM,Oliet SH,Ciofi P

更新日期：2016-03-31 00:00:00

abstract：Introduction:Optical coherence tomography angiography (OCT-A) is a novel diagnostic tool with increasing applications in ophthalmology clinics that provides non-invasive high-resolution imaging of the retinal microvasculature. Our aim is to report in detail an experimental protocol for analyzing both vasodilatory and v...

journal_title：Frontiers in neuroscience

authors： Sousa DC,Leal I,Moreira S,do Vale S,Silva-Herdade AS,Aguiar P,Dionísio P,Abegão Pinto L,Castanho MARB,Marques-Neves C

更新日期：2019-06-12 00:00:00

abstract：:Relative positions of neurons within mature murine pelvic ganglia based on expression of neurotransmitters have been described. However the spatial organization of developing innervation in the murine urogenital tract (UGT) and the gene networks that regulate specification and maturation of neurons within the pelvic g...

journal_title：Frontiers in neuroscience

authors： Wiese CB,Ireland S,Fleming NL,Yu J,Valerius MT,Georgas K,Chiu HS,Brennan J,Armstrong J,Little MH,McMahon AP,Southard-Smith EM

更新日期：2012-09-12 00:00:00

abstract：:Brain-machine interfaces (BMIs) seek to connect brains with machines or computers directly, for application in areas such as prosthesis control. For this application, the accuracy of the decoding of movement intentions is crucial. We aim to improve accuracy by designing a better encoding model of primary motor cortica...

journal_title：Frontiers in neuroscience

authors： Li S,Li J,Li Z

更新日期：2016-12-22 00:00:00

abstract：:Perinatal exposure to endocrine disrupting chemicals (EDCs) can induce promiscuous neurobehavioral disturbances. Bisphenol A and phthalates are two widely prevalent and persistent EDCs reported to lead to such effects. Parental and social behaviors are especially vulnerable to endocrine disruption, as these traits are...

journal_title：Frontiers in neuroscience

authors： Rosenfeld CS

更新日期：2015-03-03 00:00:00

abstract：Purpose:To improve the metoprolol therapeutic effectiveness, we aimed to explore whether baseline heart rate variability (HRV) indicators before metoprolol treatment were useful for predicting its efficacy for postural tachycardia syndrome (POTS). Methods:We recruited 45 children with POTS who received metoprolol and ...

journal_title：Frontiers in neuroscience

authors： Wang Y,Zhang C,Chen S,Liu P,Wang Y,Tang C,Jin H,Du J

更新日期：2019-11-12 00:00:00

abstract：:Resting-state functional connectivity (RSFC) has been generally assessed with functional magnetic resonance imaging (fMRI) thanks to its high spatial resolution. However, fMRI has several disadvantages such as high cost and low portability. In addition, fMRI may not be appropriate for people with metal or electronic i...

journal_title：Frontiers in neuroscience

authors： Aihara T,Shimokawa T,Ogawa T,Okada Y,Ishikawa A,Inoue Y,Yamashita O

更新日期：2020-01-31 00:00:00

abstract：:Brain functional connectivity network (BFCN) analysis has been widely used in the diagnosis of mental disorders, such as schizophrenia. In BFCN methods, brain network construction is one of the core tasks due to its great influence on the diagnosis result. Most of the existing BFCN construction methods only consider t...

journal_title：Frontiers in neuroscience

authors： Zhu Q,Li H,Huang J,Xu X,Guan D,Zhang D

更新日期：2019-06-14 00:00:00

abstract：:The Ossification of the Posterior Longitudinal Ligament (OPLL) is an idiopathic degenerative spinal disease which may cause motor deficit. For patients presenting myelopathy or severe stenosis, surgical decompression is the treatment of choice; however, despite adequate decompression residual motor impairment is found...

journal_title：Frontiers in neuroscience

authors： Puentes S,Kadone H,Kubota S,Abe T,Shimizu Y,Marushima A,Sankai Y,Yamazaki M,Suzuki K

更新日期：2018-03-02 00:00:00

abstract：:Environmental sounds form part of our daily life. With the advancement of deep learning models and the abundance of training data, the performance of automatic sound classification (ASC) systems has improved significantly in recent years. However, the high computational cost, hence high power consumption, remains a ma...

journal_title：Frontiers in neuroscience

authors： Wu J,Chua Y,Zhang M,Li H,Tan KC

更新日期：2018-11-19 00:00:00

abstract：:In this paper, we present an alternative approach to perform spike sorting of complex brain signals based on spiking neural networks (SNN). The proposed architecture is suitable for hardware implementation by using resistive random access memory (RRAM) technology for the implementation of synapses whose low latency (<...

journal_title：Frontiers in neuroscience

authors： Werner T,Vianello E,Bichler O,Garbin D,Cattaert D,Yvert B,De Salvo B,Perniola L

更新日期：2016-11-03 00:00:00

abstract：:Donepezil is a potent acetylcholinesterase inhibitor, largely used worldwide to alleviate cognitive symptoms in Alzheimer's disease (AD). Beyond the widely described neuronal impact of donepezil, it was recently shown that targeting connexins, the proteins involved in astrocyte network organization, potentiates donepe...

journal_title：Frontiers in neuroscience

authors： Vidal B,Droguerre M,Valdebenito M,Zimmer L,Hamon M,Mouthon F,Charvériat M

更新日期：2020-08-12 00:00:00

abstract：:The role of mitochondria within injured neurons is an area of active interest since these organelles are vital for the production of cellular energy in the form of ATP. Using mechanosensory neurons of the nematode Caenorhabditis elegans to test regeneration after neuronal injury in vivo, we surveyed genes related to m...

journal_title：Frontiers in neuroscience

authors： Knowlton WM,Hubert T,Wu Z,Chisholm AD,Jin Y

更新日期：2017-05-10 00:00:00

abstract：:The Embden-Meyerhof-Parnas (EMP) pathway comprises eleven cytosolic enzymes interacting to metabolize glucose to lactic acid [CH3CH(OH)COOH]. Glycolysis is largely considered as the conversion of glucose to pyruvate (CH3COCOO-). We consider glycolysis to be a cellular process and as such, transporters mediating glucos...

journal_title：Frontiers in neuroscience

authors： Roosterman D,Meyerhof W,Cottrell GS

更新日期：2018-06-15 00:00:00

abstract：:Abdominal obesity is important for understanding obesity, which is a worldwide medical problem. We explored structural and functional brain differences in people with abdominal and non-abdominal obesity by using multimodal neuroimaging and up-to-date analysis methods. A total of 274 overweight people, whose body mass ...

journal_title：Frontiers in neuroscience

authors： Park BY,Lee MJ,Kim M,Kim SH,Park H

更新日期：2018-10-11 00:00:00

abstract：:Increasingly, neuroimaging researchers are exploring the use of real-time functional magnetic resonance imaging (rt-fMRI) as a way to access a participant's ongoing brain function throughout a scan. This approach presents novel and exciting experimental applications ranging from monitoring data quality in real time, t...

journal_title：Frontiers in neuroscience

authors： MacInnes JJ,Adcock RA,Stocco A,Prat CS,Rao RPN,Dickerson KC

更新日期：2020-09-15 00:00:00

abstract：:Advanced algorithms are required to reveal the complex relations between neural and behavioral data. In this study, forelimb electromyography (EMG) signals were reconstructed from multi-unit neural signals recorded with multiple electrode arrays (MEAs) from the corticospinal tract (CST) in rats. A six-layer convolutio...

journal_title：Frontiers in neuroscience

authors： Guo Y,Gok S,Sahin M

更新日期：2018-10-17 00:00:00

abstract：:The R47H coding variant of the triggering receptor expressed on myeloid cells-2 (TREM2) increases the risk of Alzheimer's disease (AD) similar to apolipoprotein E4. TREM2 R47H has recently been shown to have impaired binding to damage-associated lipid or apolipoprotein ligands. However, it is not known how this R47H v...

journal_title：Frontiers in neuroscience

authors： Park JS,Ji IJ,Kim DH,An HJ,Yoon SY

更新日期：2017-01-18 00:00:00

abstract：:Traumatic brain injury (TBI) is a major public health concern that affects 69 million individuals each year worldwide. Neuropsychologists report that up to 40% of individuals undergoing evaluations for TBI may be malingering neurocognitive deficits for a compensatory reward. The memory recognition test of malingering ...

journal_title：Frontiers in neuroscience

authors： Neal J,Strothkamp S,Bedingar E,Cordero P,Wagner B,Vagnini V,Jiang Y

更新日期：2019-09-25 00:00:00

abstract：:ATP is released in an activity-dependent manner from different cell types in the brain, fulfilling different roles as a neurotransmitter, neuromodulator, in astrocyte-to-neuron communication, propagating astrocytic responses and formatting microglia responses. This involves the activation of different ATP P2 receptors...

journal_title：Frontiers in neuroscience

authors： Rodrigues RJ,Tomé AR,Cunha RA

更新日期：2015-04-28 00:00:00

abstract：:Individuals differ widely in how steeply they discount future rewards. The sources of these stable individual differences in delay discounting (DD) are largely unknown. One candidate is the COMT Val158Met polymorphism, known to modulate prefrontal dopamine levels and affect DD. To identify possible neural mechanisms b...

journal_title：Frontiers in neuroscience

authors： Gianotti LR,Figner B,Ebstein RP,Knoch D

更新日期：2012-05-07 00:00:00

abstract：:Alzheimer's disease (AD) is associated with degeneration of cholinergic neurons in the basal forebrain. Administration of the immunotoxin 192IgG-saporin to rats, an animal model of AD, leads to degeneration of cholinergic neurons in the medial septal area. In the present study, cholinergic cell death was induced by in...

journal_title：Frontiers in neuroscience

authors： Dobryakova YV,Volobueva MN,Manolova AO,Medvedeva TM,Kvichansky AA,Gulyaeva NV,Markevich VA,Stepanichev MY,Bolshakov AP

更新日期：2019-03-12 00:00:00