Switching modes in corticogenesis: mechanisms of neuronal subtype transitions and integration in the cerebral cortex.

abstract：:The visual system is organized in a parallel and hierarchical architecture. However, the plasticity in hierarchical neural networks is controversial across different response features and at different levels. In this study, we recorded areas 17 and 21a, earlier and intermediate stages of the visual cortex in the cat, ...

journal_title：Frontiers in neuroscience

authors： Wang J,Ni Z,Jin A,Yu T,Yu H

更新日期：2019-10-11 00:00:00

abstract：:The melanocortin receptors (MCRs) are a gene family in the rhodopsin class of G protein-coupled receptors. Based on the analysis of several metazoan genome databases it appears that the MCRs are only found in chordates. The presence of five genes in the family (i.e., mc1r, mc2r, mc3r, mc4r, mc5r) in representatives of...

journal_title：Frontiers in neuroscience

authors： Dores RM

更新日期：2013-04-10 00:00:00

abstract：:[This corrects the article on p. 589 in vol. 10, PMID: 28066172.]. ...

journal_title：Frontiers in neuroscience

authors： Wang H,Li X,Shan L,Zhu J,Chen R,Li Y,Yuan W,Yang L,Huang J

更新日期：2017-02-13 00:00:00

abstract：:The dynamical systems view of movement generation in motor cortical areas has emerged as an effective way to explain the firing properties of populations of neurons recorded from these regions. Recently, many studies have focused on finding low-dimensional representations of these dynamical systems during voluntary re...

journal_title：Frontiers in neuroscience

authors： Xing D,Aghagolzadeh M,Truccolo W,Borton D

更新日期：2019-10-04 00:00:00

abstract：:ATP is released in an activity-dependent manner from different cell types in the brain, fulfilling different roles as a neurotransmitter, neuromodulator, in astrocyte-to-neuron communication, propagating astrocytic responses and formatting microglia responses. This involves the activation of different ATP P2 receptors...

journal_title：Frontiers in neuroscience

authors： Rodrigues RJ,Tomé AR,Cunha RA

更新日期：2015-04-28 00:00:00

abstract：:Introduction: The presence of a temporomandibular disorder is one of the most frequent causes of orofacial pain (OFP). When pain continues beyond tissue healing time, it becomes chronic and may be caused, among other factors, by the sensitization of higher-order neurons. The aim of this study is to describe psychologi...

journal_title：Frontiers in neuroscience

authors： Baroni A,Severini G,Straudi S,Buja S,Borsato S,Basaglia N

更新日期：2020-11-12 00:00:00

abstract：:Encouraged by a rise of reciprocal interest between the machine learning and neuroscience communities, several recent studies have demonstrated the explanatory power of statistical learning techniques for the analysis of neural data. In order to facilitate a wider adoption of these methods, neuroscientific research ne...

journal_title：Frontiers in neuroscience

authors： Hanke M,Halchenko YO,Haxby JV,Pollmann S

更新日期：2010-05-15 00:00:00

abstract：:Olfaction is a sense involved in a complex set of tasks, influencing eating behavior, increasing awareness of environmental hazards and affecting social communication. Surprisingly, smell disorders are very frequent, especially in the elderly population. Several recent studies conducted mostly in older subjects have d...

journal_title：Frontiers in neuroscience

authors： Van Regemorter V,Hummel T,Rosenzweig F,Mouraux A,Rombaux P,Huart C

更新日期：2020-02-21 00:00:00

abstract：:Neurodegenerative diseases, including Alzheimer, Parkinson, Huntington, and amyotrophic lateral sclerosis, are a prominent class of neurological diseases currently without a cure. They are characterized by an inexorable loss of a specific type of neurons. The selective vulnerability of specific neuronal clusters (typi...

journal_title：Frontiers in neuroscience

authors： Muddapu VR,Dharshini SAP,Chakravarthy VS,Gromiha MM

更新日期：2020-03-31 00:00:00

abstract：:Compelling data demonstrate that inflammation-associated anorexia directly results from the action of pro-inflammatory factors, primarily cytokines and prostaglandins E2, on the nervous system. For instance, the aforementioned pro-inflammatory factors can stimulate the activity of peripheral sensory neurons, and induc...

journal_title：Frontiers in neuroscience

authors： Gautron L,Layé S

更新日期：2010-01-08 00:00:00

abstract：:Previous studies have demonstrated that total flavonoid extracts from Caragana sinica (TFC) exert multiple therapeutic effects, promote blood flow, and exhibit anti-inflammatory and antioxidant properties. The present study aimed to investigate whether TFC promotes angiogenesis and exerts neuroprotective effects in a ...

journal_title：Frontiers in neuroscience

authors： He Q,Li S,Li L,Hu F,Weng N,Fan X,Kuang S

更新日期：2018-09-12 00:00:00

abstract：:Changes in cerebral blood flow (CBF) during a hyperglycemic challenge were mapped, using perfusion-weighted MRI, in a group of non-human primates. Seven female baboons were fasted for 16 h prior to 1-h imaging experiment, performed under general anesthesia, that consisted of a 20-min baseline, followed by a bolus infu...

journal_title：Frontiers in neuroscience

authors： Kochunov P,Wey HY,Fox PT,Lancaster JL,Davis MD,Wang DJ,Lin AL,Bastarrachea RA,Andrade MC,Mattern V,Frost P,Higgins PB,Comuzzie AG,Voruganti VS

更新日期：2017-02-14 00:00:00

abstract：:Depression is a highly heterogeneous disease characterized by symptoms spanning from anhedonia and behavioral despair to social withdrawal and learning deficit. Such diversity of behavioral phenotypes suggests that discrete neural circuits may underlie precise aspects of the disease, rendering its treatment an unmet c...

journal_title：Frontiers in neuroscience

authors： Nuno-Perez A,Tchenio A,Mameli M,Lecca S

更新日期：2018-07-23 00:00:00

abstract：:Obesity is known to induce leptin and insulin resistance. Leptin is a peptide hormone synthesized in adipose tissue that mainly regulates food intake. It has been shown that insulin stimulates the production of leptin when adipocytes are exposed to glucose to encourage satiety; while leptin, via a negative feedback, d...

journal_title：Frontiers in neuroscience

authors： Lloret A,Monllor P,Esteve D,Cervera-Ferri A,Lloret MA

更新日期：2019-05-22 00:00:00

abstract：:The blood-brain barrier (BBB) mediates the communication between the periphery and the central nervous system (CNS). Recently, CNS insulin resistance has been elucidated to play a role in neurodegenerative disease. This has stimulated a wealth of information on the molecular impact of insulin in the brain, particularl...

journal_title：Frontiers in neuroscience

authors： Rhea EM,Banks WA

更新日期：2019-06-04 00:00:00

abstract：:Posttraumatic stress disorder (PTSD) is an anxiety disorder characterized by intrusive recollections of a severe traumatic event and hyperarousal following exposure to the event. Human and animal studies have shown that the change of amygdala activity after traumatic stress may contribute to occurrences of some sympto...

journal_title：Frontiers in neuroscience

authors： Fang Q,Li Z,Huang GD,Zhang HH,Chen YY,Zhang LB,Ding ZB,Shi J,Lu L,Yang JL

更新日期：2018-08-21 00:00:00

abstract：:Recent progress in tissue engineering has led to increasingly complex approaches to investigate human neurodegenerative diseases in vitro, such as Alzheimer's disease, aiming to provide more functional and physiological models for the study of their pathogenesis, and possibly the identification of novel diagnostic bio...

journal_title：Frontiers in neuroscience

authors： Brighi C,Cordella F,Chiriatti L,Soloperto A,Di Angelantonio S

更新日期：2020-06-17 00:00:00

abstract：:Neuromorphic Vision sensors have improved greatly since the first silicon retina was presented almost three decades ago. They have recently matured to the point where they are commercially available and can be operated by laymen. However, despite improved availability of sensors, there remains a lack of good datasets,...

journal_title：Frontiers in neuroscience

authors： Tan C,Lallee S,Orchard G

更新日期：2015-10-13 00:00:00

abstract：:Brain-derived neurotrophic factor (BDNF) is a potent regulator of neuronal development and synaptic plasticity that is fundamental to neural circuit formation and cognition. It is also involved in the control of appetite and body weight, with mutations in the genes for BDNF and its receptor, TrkB, resulting in remarka...

journal_title：Frontiers in neuroscience

authors： Vanevski F,Xu B

更新日期：2013-03-21 00:00:00

abstract：:The Embden-Meyerhof-Parnas (EMP) pathway comprises eleven cytosolic enzymes interacting to metabolize glucose to lactic acid [CH3CH(OH)COOH]. Glycolysis is largely considered as the conversion of glucose to pyruvate (CH3COCOO-). We consider glycolysis to be a cellular process and as such, transporters mediating glucos...

journal_title：Frontiers in neuroscience

authors： Roosterman D,Meyerhof W,Cottrell GS

更新日期：2018-06-15 00:00:00

abstract：:Orexin neuropeptides influence multiple homeostatic functions and play an essential role in the expression of normal sleep-wake behavior. While their two known receptors (OX1 and OX2) are targets for novel pharmacotherapeutics, the actions mediated by each receptor remain largely unexplored. Using brain slices from mi...

journal_title：Frontiers in neuroscience

authors： Kohlmeier KA,Tyler CJ,Kalogiannis M,Ishibashi M,Kristensen MP,Gumenchuk I,Chemelli RM,Kisanuki YY,Yanagisawa M,Leonard CS

更新日期：2013-12-20 00:00:00

abstract：:SpiNNaker is a digital neuromorphic architecture, designed specifically for the low power simulation of large-scale spiking neural networks at speeds close to biological real-time. Unlike other neuromorphic systems, SpiNNaker allows users to develop their own neuron and synapse models as well as specify arbitrary conn...

journal_title：Frontiers in neuroscience

authors： Mikaitis M,Pineda García G,Knight JC,Furber SB

更新日期：2018-02-27 00:00:00

abstract：:Neural stem cells-based therapies have shown great potential for central nervous system regeneration, with three-dimensional (3D) culture systems representing a key technique for tissue engineering applications, as well as disease modeling and drug screenings. Self-assembling peptides (SAPs), providing biomimetic synt...

journal_title：Frontiers in neuroscience

authors： Marchini A,Favoino C,Gelain F

更新日期：2020-05-05 00:00:00

abstract：Objective:Magnetic resonance-guided focused ultrasound surgery (MRgFUS) lesioning is a new treatment for brain disorders. However, the skull is a major barrier of ultrasound sonication in MRgFUS because it has an irregular surface and varies its size and shape among individuals. We recently developed the concept of sku...

journal_title：Frontiers in neuroscience

authors： Chang KW,Rachmilevitch I,Chang WS,Jung HH,Zadicario E,Prus O,Chang JW

更新日期：2021-01-12 00:00:00

abstract：:Neuroscientific imaging evidence (NIE) has become an integral part of the criminal justice system in the United States. However, in most legal cases, NIE is submitted and used only to mitigate penalties because the court does not recognize it as substantial evidence, considering its lack of reliability. Nevertheless, ...

journal_title：Frontiers in neuroscience

authors： Jun J,Yoo S

更新日期：2018-03-01 00:00:00

abstract：:Gene editing is an attractive potential treatment of inherited retinopathies. However, it often relies on endogenous DNA repair. Retinal DNA repair is incompletely characterized in humans and animal models. We investigated recruitment of the double stranded break (DSB) repair complex of γH2AX and 53bp1 in both develop...

journal_title：Frontiers in neuroscience

authors： Müller B,Ellinwood NM,Lorenz B,Stieger K

更新日期：2018-05-01 00:00:00

abstract：:Schizophrenia is a severe neuropsychiatric disorder with persistence of symptoms throughout adult life in most of the affected patients. This unfavorable course is associated with multiple episodes and residual symptoms, mainly negative symptoms and cognitive deficits. The neural diathesis-stress model proposes that p...

journal_title：Frontiers in neuroscience

authors： Popovic D,Schmitt A,Kaurani L,Senner F,Papiol S,Malchow B,Fischer A,Schulze TG,Koutsouleris N,Falkai P

更新日期：2019-03-21 00:00:00

abstract：:Dopamine system plays a pivotal role in specific kinds of substance use disorders (SUD, i. e., cocaine and methamphetamine use disorders). Many studies addressed whether dopamine-involved craving could be alleviated by non-invasive brain stimulation (NIBS) techniques. Nevertheless, the outcomes were highly inconsisten...

journal_title：Frontiers in neuroscience

authors： Ma T,Sun Y,Ku Y

更新日期：2019-10-18 00:00:00

abstract：:Hemispheric asymmetry of hippocampal volume is a common finding that has biological relevance, including associations with dementia and cognitive performance. However, a recent study has reported the possibility of systematic error in measurements of hippocampal asymmetry by magnetic resonance volumetry. We manually t...

journal_title：Frontiers in neuroscience

authors： Rogers BP,Sheffield JM,Luksik AS,Heckers S

更新日期：2012-12-13 00:00:00

abstract：:With emerging evidence showing a wide distribution of secretin (SCT) and its receptor (SCTR) in the central nervous system (CNS), the putative neuropeptide role of SCT has become more appreciated since the disruption of SCT/SCTR axis affects various neural functions. This mini review thus focuses on the effects of SCT...

journal_title：Frontiers in neuroscience

authors： Wang L,Zhang L

更新日期：2020-05-06 00:00:00