Abstract:
INTRODUCTION:The correlation of Chlamydia pneumoniae to coronary artery disease (CAD) in Jordan was investigated in this study. METHODOLOGY:Totals of 361 atherosclerotic patients and 392 apparently healthy controls of both sexes were enrolled. C. pneumoniae-specific IgG antibodies were measured by the microimmunofluorescence assay (MIF). The presence of the bacterial DNA in the blood by polymerase chain reaction (PCR) was also tested. RESULTS:The overall IgG seroprevalence, estimated at a titer of 1/16, was insignificantly higher in patients (75.9%) than in controls (71.7%). About 59.3% of patients demonstrated seropositivity at titers ≤ 1/256, which are suggestive of chronic or presumed past infection, whereas 54.1% of controls were seropositive at these titers (p > 0.05). Analysis of gender-specific seroprevalences revealed no obvious relation between C. pneumoniae and atherosclerosis in males (78.9% and 77.9% in atherosclerotic and control males, respectively; p > 0.05). However, a significantly elevated seropositivity was detected in atherosclerotic females (71.7%) compared with control females (64.2%). On the other hand, the PCR-based detection of C. pneumoniae DNA failed to correlate the bacterium to atherosclerosis. CONCLUSIONS:We were unable to show a strong association between C. pneumoniae and CAD, potentially because of the presence of high seroprevalence of C. pneumoniae antibodies and the unreliability of the whole blood-based nested PCR technique used.
journal_name
J Infect Dev Ctriesjournal_title
Journal of infection in developing countriesauthors
Al-Younes HM,Abu Abeeleh MA,Jaber BMdoi
10.3855/jidc.7363subject
Has Abstractpub_date
2016-05-31 00:00:00pages
457-64issue
5eissn
2036-6590issn
1972-2680journal_volume
10pub_type
杂志文章abstract::Although malaria is endemic in India, neonatal disease is considered rare. We report a case of neonatal malaria in a 26-day-old neonate with fever and splenomegaly who was diagnosed after a long and unsuccessful battery of tests for splenomegaly. Routine screening for malaria is essential for all neonates with fever i...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.1623
更新日期:2011-07-04 00:00:00
abstract:INTRODUCTION:Bacille Calmette-Guerin (BCG) vaccination remains a routine immunization in primary care in tuberculosis (TB)-endemic areas, though several studies found that its efficacy was inconclusive. Natural resistance-asociated machrophage protein 1 (NRAMP1) polymorphism has been shown to result in higher susceptib...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.5047
更新日期:2015-01-15 00:00:00
abstract:INTRODUCTION:Essential oils have been used since ancient times and are known for their anti-inflammatory, anti-depressive, antiseptic, antifungal and antimicrobial properties. METHODOLOGY:in this study the antimicrobial activity of two essential oils from Melaleuca alternifolia and Thymus vulgaris-red thyme geraniol w...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.10988
更新日期:2018-11-30 00:00:00
abstract::Gonococcal urethritis is common with HIV, but gonococcal arthritis is rare. We report two HIV-positive patients with gonococcal arthritis and review previously published reports. A 27-year-old HIV-positive female presented with a pustular skin rash and acute oligoarthritis. Neisseria gonorrhoeae was cultured from the ...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.4450
更新日期:2014-09-12 00:00:00
abstract:INTRODUCTION:The impact of mutations in the reverse transcriptase region of HBV on serum HBsAg titer and its correlation with HBV DNA is largely unknown. METHODOLOGY:A total of 644 patients, with a history of lamivudine or adefovir dipivoxil resistance who underwent genotypic resistance tests, were enrolled in this st...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.11447
更新日期:2019-11-30 00:00:00
abstract:INTRODUCTION:Helicobacter pylori is a principal cause of gastric cancer. The aim of this study was to determine the prevalence and contribution of duodenal ulcer promoting gene A (dupA), the plasticity region genes and sigma factors in relation to their pathological expression of H. pylori infections in the Nigerian po...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.11746
更新日期:2020-02-29 00:00:00
abstract:BACKGROUND:Infection with Herpes Simplex Virus Type-2 (HSV-2) is the primary cause of genital herpes and the most common cause of genital ulcer disease (GUD) worldwide. There is little information on the prevalence of HSV-2 in Nigeria. METHODOLOGY:Specimens were collected from 162 volunteers attending Jos University ...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.567
更新日期:2010-10-04 00:00:00
abstract:INTRODUCTION:The aim of this study was to assess tuberculosis (TB) knowledge, attitudes, and practices in both the general population and risk groups in Thailand. METHODOLOGY:In a cross-sectional survey, a general population (n = 3,074) and family members of a TB patient (n = 559) were randomly selected, using stratif...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.6963
更新日期:2016-08-02 00:00:00
abstract:INTRODUCTION:The present study was conducted to evaluate the prevalence of Trichuris spp. and other intestinal parasitic infections in owned cats on St. Kitts. METHODOLOGY:The feces of 41 non-feral cats (23 indoor only; 18 indoor/outdoor) were examined for the presence of Trichuris spp. eggs. RESULTS:Nine (22%) of th...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.5778
更新日期:2015-01-15 00:00:00
abstract::Tuberculosis (TB) remains a serious public health problem, worsened by an increased frequency of multidrug-resistant (MDR) Mycobacterium tuberculosis strains. The World Health Organization (WHO) and the International Union Against Tuberculosis and Lung Disease (IUATLD) launched the Global Project on Anti-Tuberculosis ...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章,评审
doi:10.3855/jidc.31
更新日期:2009-04-30 00:00:00
abstract::Enterohaemorrhagic E. coli (EHEC) particularly O157:H7 (Sequence type 11 complex), is the best documented and most well-known of E. coli that cause diarrhoea. The importance of EHEC lies in the severity of disease. Outbreaks can infect thousands of people causing bloody diarrhoea and haemolytic uremic syndrome (HUS) t...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章,评审
doi:10.3855/jidc.2166
更新日期:2011-07-04 00:00:00
abstract:INTRODUCTION:Human co-infection with Plasmodium falciparum and helminthes is ubiquitous throughout Africa. This study aimed to determine the co-infections of Plasmodium falciparum infection in HIV and intestinal parasitic infections, and their immunological distribution, in Benin City, Nigeria. METHODOLOGY:A total of ...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.1889
更新日期:2012-05-14 00:00:00
abstract::Zika virus (ZIKV) infection is spreading rapidly within the Americas after originating from an outbreak in Brazil. We describe the current ZIKV infection epidemic in Brazil and the neurological symptoms arising. First cases of an acute exanthematic disease were reported in Brazil's Northeast region at the end of 2014....
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.8217
更新日期:2016-02-28 00:00:00
abstract:INTRODUCTION:Norovirus is not usually investigated in diarrheal patients in Bangladesh which may account for the many cases where no pathogens are identified. METHODOLOGY:Stool specimens collected from diarrheal patients from three hospitals in Bangladesh during 2011 were investigated for norovirus RNA using real-time...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.2944
更新日期:2013-11-15 00:00:00
abstract::The case of a Hickman catheter-related bacteremia caused by Gordonia sputi in a patient with breast cancer is presented. Blood cultures grew a Gram-positive rod, susceptible to several antimicrobials, subsequently identified by 16S rRNA gene sequencing as Gordonia sputi. The infection resolved after successful treatme...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.1770
更新日期:2012-02-13 00:00:00
abstract:INTRODUCTION:The goal of this study was to evaluate whether any characteristics that are evident at presentation for urgent medical attention could be used to differentiate cases of H5N1 in the absence of viral testing. METHODOLOGY:Information about exposure to poultry, clinical signs and symptoms, treatments, and out...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.3329
更新日期:2014-02-13 00:00:00
abstract:INTRODUCTION:Antimicrobial stewardship practices are crucial for the regular surveillance to change the antimicrobial policy. This study was conducted to decide the prevalence of common bacteria and their antibiogram regarding antimicrobial stewardship program within one year, at the regional and district, Stanger hosp...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.10685
更新日期:2019-08-31 00:00:00
abstract:INTRODUCTION:Staphylococcus aureus is considered one of the most important human pathogens, and its levels of resistance to methicillin have increased even in strains isolated from people without nosocomial risk factors. Molecular analysis is essential for understanding the patterns of dissemination. The objective of t...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章,多中心研究
doi:10.3855/jidc.12108
更新日期:2020-03-31 00:00:00
abstract::Brucellosis is an endemic disease in developing countries. The most commonly observed complications include bone-joint involvement, particularly sacroiliitis and spondylitis. Epidural abscesses caused by brucellosis are a rare complication. We describe the case of a 33-year-old man presenting with high fever, back pai...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.1470
更新日期:2011-05-28 00:00:00
abstract:INTRODUCTION:Clostridium difficile is the leading cause of hospital-acquired diarrhoea. There is no defined protocol for treating severe Clostridium difficile infection (CDI) refractory to vancomycin or vancomycin and metronidazole combination therapy. The aim of this study was to evaluate the rate of clinical cure, ti...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.6335
更新日期:2015-10-29 00:00:00
abstract:INTRODUCTION:Use of herbal remedies among HIV-infected individuals in Africa increased in the past decade, mainly due to traditional beliefs and at times inconsistent access to antiretroviral drugs. In Zimbabwe, accessibility and availability of antiretroviral drugs has increased in recent years; however, the use of he...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.1415
更新日期:2011-02-01 00:00:00
abstract:INTRODUCTION:Although tuberculosis (TB) is frequently seen in Turkey, there are limited studies on childhood TB. We aimed to describe clinical and laboratory findings, including drug resistance, of children with TB in Istanbul, Turkey. METHODOLOGY:The study included all children aged 0-14 years who were registered in ...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.3950
更新日期:2014-03-13 00:00:00
abstract:INTRODUCTION:Most sexually transmitted infections (STIs) are curable, but inappropriate treatment can lead to serious complications. The importance of setting up STI screening programs has been highlighted in various studies, the absence of such national programs accounting for the lack of STI statistics in Romania. Th...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.11989
更新日期:2020-04-30 00:00:00
abstract:INTRODUCTION:The distribution of both malaria and schistosomiasis exhibits a large geographical overlap in tropical environments, particularly in sub-Saharan Africa. This part of the world currently harbours more than 85% of the estimated global burden of these diseases. Studies showed that artemisinin derivatives used...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.2658
更新日期:2013-06-15 00:00:00
abstract:INTRODUCTION:Although omphalitis (umbilical infections) among newborns is common and a major cause of neonatal deaths in developing countries, information on its burden and etiology from community settings is lacking. This study aimed to determine the incidence and etiology of omphalitis in newborns in high neonatal mo...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章,评审
doi:10.3855/jidc.1229
更新日期:2011-12-13 00:00:00
abstract::Leukocyte adhesion deficiency type 1 (LAD-1) is a rare, inherited immunodeficiency that affects one per million people yearly and usually presents with recurrent, indolent bacterial infections of the skin, mouth, and respiratory tract and impaired pus formation and wound healing. A 13-year-old girl diagnosed LAD-I at ...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.387
更新日期:2010-03-29 00:00:00
abstract:INTRODUCTION:Women infected with human immunodeficiency virus (HIV) have a higher risk of contracting human papillomavirus (HPV) infections and are more prone to develop cervical cancer. The objective of this study was to determine the prevalence of HPV and its association with risk factors among Moroccan women living ...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.9711
更新日期:2018-06-30 00:00:00
abstract:INTRODUCTION:We investigated the frequency of H274Y-positive swine-origin 2009 A (H1N1) influenza virus outbreak in Thailand during May-August 2009. METHODOLOGY:This study sought to find Oseltamivir resistance mutation H274Y by using pyrosequencing. RESULTS:From 8,710 real-time RT-PCR swine-origin 2009 A(H1N1) influ...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.1197
更新日期:2011-05-28 00:00:00
abstract:INTRODUCTION:Due to intercontinental traffic, population migration trends, natural disasters, and climate change, imported malaria remains important to consider in a febrile returning traveler. This study aims to raise awareness about malaria and help European clinicians maintain a working knowledge of this disease by ...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.6799
更新日期:2016-08-02 00:00:00
abstract:BACKGROUND:Chikungunya is an acute viral infection presenting with a febrile episode and severe arthralgia, swelling of soft tissues, especially around the ankles. Many patients recover with nonspecific treatment of analgesics. Some patients continue to have subacute crippling arthritis in the legs affecting their mobi...
journal_title:Journal of infection in developing countries
pub_type: 临床试验,杂志文章
doi:
更新日期:2008-04-01 00:00:00