Abstract:
:Enterohaemorrhagic E. coli (EHEC) particularly O157:H7 (Sequence type 11 complex), is the best documented and most well-known of E. coli that cause diarrhoea. The importance of EHEC lies in the severity of disease. Outbreaks can infect thousands of people causing bloody diarrhoea and haemolytic uremic syndrome (HUS) that in turn can result in protracted illness or even death. The ability of EHEC to colonise the human gut is normally associated with the presence of genes from another group of diarrhoeagenic E. coli, the enteropathogenic E. coli (EPEC), via the locus of enterocyte effacement. However, the massive outbreak in Germany was caused by an EHEC which had acquired virulence genes from yet another group of diarrhoeagenic E. coli, the enteroaggregative E. coli (EAEC). In reality EAEC is probably the most common bacterial cause of diarrhoea but is not identified in most diagnostic laboratories. This outbreak emphasises the importance of being able to detect all diarrhoeagenic E. coli and not to focus on E. coli O157:H7 alone. Routine surveillance systems for EAEC, a once ignored global pathogen, would go a long way to reaching this goal. This review describes methods for identifying non-O157 EHEC and describes the key genetic features of EHEC and EAEC. Our aim is to provide information for laboratories and policy makers which enables them to make informed decisions about the best methods available for detecting newly emergent strains of diarrhoeagenic E. coli.
journal_name
J Infect Dev Ctriesjournal_title
Journal of infection in developing countriesauthors
Chattaway MA,Dallman T,Okeke IN,Wain Jdoi
10.3855/jidc.2166subject
Has Abstractpub_date
2011-07-04 00:00:00pages
425-36issue
6eissn
2036-6590issn
1972-2680journal_volume
5pub_type
杂志文章,评审abstract:INTRODUCTION:Evaluating the attenuation of influenza viruses in animal studies is important in developing safe and effective vaccines. This study aimed to demonstrate that the microRNA (miRNA)-let-7b-mediated attenuated influenza viruses (miRT-H1N1) are sufficiently attenuated and safe in mice. METHODOLOGY:The pathoge...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.6861
更新日期:2016-09-30 00:00:00
abstract:INTRODUCTION:Live poultry exposure and risk behaviors are more prevalent in rural communities, increasing the risk of influenza A/H5N1 infection. We examined the economic and socio-cultural influences on poultry-related practices by comparing the poultry-related practices among Vietnamese and Thai rural residents by fa...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.3545
更新日期:2014-04-15 00:00:00
abstract:INTRODUCTION:Staphylococcal colonization is a risk factor for healthcare-associated infections, which are frequent in Neonatal Intensive Care Units (NICU). This study analyzed microbiology, epidemiology and clinical aspects of Staphylococcus spp. colonizing neonates. METHODOLOGY:Nasal or periumbilical swabs were evalu...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.11241
更新日期:2019-09-30 00:00:00
abstract:INTRODUCTION:The correlation of Chlamydia pneumoniae to coronary artery disease (CAD) in Jordan was investigated in this study. METHODOLOGY:Totals of 361 atherosclerotic patients and 392 apparently healthy controls of both sexes were enrolled. C. pneumoniae-specific IgG antibodies were measured by the microimmunofluor...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.7363
更新日期:2016-05-31 00:00:00
abstract:INTRODUCTION:Taenia solium cysticercosis is considered an emerging parasitic zoonosis of global importance due to its impact on both agriculture and public health in developing countries. Epidemiological information on human cysticercosis is limited in Nigeria. This study was conducted to determine the seroprevalence o...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.5415
更新日期:2015-08-29 00:00:00
abstract:INTRODUCTION:Pneumocystis jirovecii (PJ) pneumonia (PJP) is an important opportunistic infection affecting various types of immunocompromised patients and is associated with an increased risk of mortality. PJ is a unique fungal pathogen which is increasingly common and maybe associated with a higher mortality rate in p...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.10357
更新日期:2018-10-31 00:00:00
abstract::A clinical case of infection caused by Fasciolopsis buski in a 24 weeks pregnant woman from Vietnam affected by systemic lupus erythematosus (SLE) is reported here. On 22 February 2012 the patient was admitted to Hue Hospital in Hue, Vietnam, with a diagnosis of general illness and suspected acute anaemia. Laboratory ...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.7017
更新日期:2015-07-04 00:00:00
abstract:INTRODUCTION:Acute respiratory infections (ARIs) are major causes of morbidity in early childhood. They are mainly caused by viruses, including influenza (INF) and respiratory syncytial viruses (RSV). We aimed to investigate the role of RSV and INF in children hospitalized for ARIs and to show the impact of RSV/INF rap...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.11386
更新日期:2019-05-16 00:00:00
abstract:INTRODUCTION:The goal of this study was to evaluate whether any characteristics that are evident at presentation for urgent medical attention could be used to differentiate cases of H5N1 in the absence of viral testing. METHODOLOGY:Information about exposure to poultry, clinical signs and symptoms, treatments, and out...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.3329
更新日期:2014-02-13 00:00:00
abstract:INTRODUCTION:Nosocomial pneumonia (NP) and ventilator associated pneumonia (VAP) occur most frequently in intensive care units (ICU). This study seeks to determine the etiological agents of NP and VAP along with their antibacterial susceptibility patterns, and to evaluate the factors contributing to patient mortality. ...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.1212
更新日期:2011-04-26 00:00:00
abstract:INTRODUCTION:The present study was conducted to evaluate the prevalence of Trichuris spp. and other intestinal parasitic infections in owned cats on St. Kitts. METHODOLOGY:The feces of 41 non-feral cats (23 indoor only; 18 indoor/outdoor) were examined for the presence of Trichuris spp. eggs. RESULTS:Nine (22%) of th...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.5778
更新日期:2015-01-15 00:00:00
abstract:BACKGROUND:This study was conducted to examine the frequency of contamination in retail meat available in Karachi, Pakistan. METHODOLOGY:Raw meat samples (250) and surface swabs (90) from meat processing equipment and the surrounding environment were analyzed for microbiological contamination. RESULTS:Out of 340 samp...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:
更新日期:2010-06-30 00:00:00
abstract:INTRODUCTION:Multidrug resistance tuberculosis (MDR-TB) is a continuing threat because the treatment is rather toxic. One of the causes of poor treatment outcome is due to the adverse events, especially the occurrence of psychiatric adverse events. METHODOLOGY:The two cases presented in this paper are MDR-TB patients ...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.10352
更新日期:2018-07-31 00:00:00
abstract:INTRODUCTION:Salmonella is well recognized as an aetiological agent of gastrointestinal and diarrhoeal disease. Salmonella enterica serotype Enteritidis (Salmonella Enteritidis) is one of the commonest serotypes associated with foodborne illness. In South Africa, we compared Salmonella Enteritidis strains isolated from...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.5393
更新日期:2014-12-15 00:00:00
abstract:INTRODUCTION:Inadequate hand-washing facilities have been reported as a barrier to hand washing. This study aimed to evaluate the availability and accessibility of hand-washing facilities and supplies of hand-washing agents in the outpatient department (OPD) complex of a tertiary care teaching hospital. METHODOLOGY:A ...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.1003
更新日期:2011-03-02 00:00:00
abstract:INTRODUCTION:Norovirus (NoV) is a contagious virus causing acute gastroenteritis and is mainly responsible for diarrheal outbreak in closed settings. The aims of this study were to describe the epidemiological characteristic of an outbreak in a boarding school, to assess the extent of the outbreak and to implement appr...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.11199
更新日期:2019-04-30 00:00:00
abstract:INTRODUCTION:Infections caused by multidrug-resistant bacteria are increasingly common and represent a serious problem for public health. Staphylococcus aureus is one of the major agents of infections, and methicillin-resistant S. aureus (MRSA) has spread worldwide. The aim of this study was to phenotypically and genot...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.7887
更新日期:2016-12-30 00:00:00
abstract::Orthotopic liver transplantation is a life-saving procedure for patients with end-stage liver failure. However, Acinetobacter baumannii infections and acute rejection are important causes of morbidity and mortality following transplants. Here we present a case report of a cadaveric donor liver transplantation with inf...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.11842
更新日期:2020-04-30 00:00:00
abstract:INTRODUCTION:Association between Ascaris lumbricoides infection and asthma is a controversial subject that has been studied by several authors based on the hygiene theory. This work contributes to better understanding this issue. METHODOLOGY:This was a cross-sectional study involving 1,004 children from a neighborhood...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.3585
更新日期:2014-07-14 00:00:00
abstract:INTRODUCTION:In Georgia as in most Eastern European countries, injecting drug use remains one of the leading transmission modes of HIV infection. This paper aims to identify HIV prevalence and risk determinants among people who inject drugs (PWID). METHODOLOGY:A cross -sectional, anonymous bio-behavioral survey of PWI...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.9103
更新日期:2017-10-31 00:00:00
abstract:INTRODUCTION:Essential oils have been used since ancient times and are known for their anti-inflammatory, anti-depressive, antiseptic, antifungal and antimicrobial properties. METHODOLOGY:in this study the antimicrobial activity of two essential oils from Melaleuca alternifolia and Thymus vulgaris-red thyme geraniol w...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.10988
更新日期:2018-11-30 00:00:00
abstract:INTRODUCTION:Fungi of the genus Cryptococcus are cosmopolitan and may be agents of opportunistic mycoses in immunocompromised and sometimes immunocompetent individuals. Cryptococcus species are frequently isolated from trees and bird excreta in the environment and infection occurs by inhalation of propagules dispersed ...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.10849
更新日期:2019-06-30 00:00:00
abstract:INTRODUCTION:The distribution of both malaria and schistosomiasis exhibits a large geographical overlap in tropical environments, particularly in sub-Saharan Africa. This part of the world currently harbours more than 85% of the estimated global burden of these diseases. Studies showed that artemisinin derivatives used...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.2658
更新日期:2013-06-15 00:00:00
abstract::Brucellosis is an emergent and endemic zoonotic disease in Bosnia and Herzegovina. In this report we have diagnosed the first case of human brucellosis in Bosnia and Herzegovina, using molecular and microbiological tests, caused by live attenuated Brucella melitensis Rev.1 strain. The infection was caused through unin...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.11949
更新日期:2020-02-29 00:00:00
abstract:INTRODUCTION:Although omphalitis (umbilical infections) among newborns is common and a major cause of neonatal deaths in developing countries, information on its burden and etiology from community settings is lacking. This study aimed to determine the incidence and etiology of omphalitis in newborns in high neonatal mo...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章,评审
doi:10.3855/jidc.1229
更新日期:2011-12-13 00:00:00
abstract:INTRODUCTION:Intestinal and extraintestinal infections by Aeromonas spp., remain controversial, due to the existence of healthy carriers of Aeromonas spp. In children under five years old, the diarrhea of infectious origin constitutes the second cause of mortality and remains a major concern for public health. The aim ...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.12966
更新日期:2020-10-31 00:00:00
abstract:INTRODUCTION:Pancreatitis is a rare complication of hemorrhagic fever with renal syndrome (HFRS). The causative agents of HFRS are hantaviruses, which belong to the genus Hantavirus, family Bunyaviridae. The purpose of this study was to evaluate cases of acute pancreatitis (AP) in patients with HFRS at the Service of I...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.9567
更新日期:2017-12-10 00:00:00
abstract:INTRODUCTION:Imported parasitosis, which do not require an invertebrate vector, are extremely dangerous and can lead to the occurrence of disease in currently parasite free areas. In the present study we report a case of multi-parasitic infection in a young immigrant from Ghana to Italy caused by filaria, Schistosoma s...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.13151
更新日期:2020-11-30 00:00:00
abstract:INTRODUCTION:Human papillomavirus (HPV) infection is typically critical in the oncogenesis of cervical cancer. However, available HPV detection kits differ in their ability and sensitivity to detect various types of HPV, and this variability has led to inconsistencies in the reporting of the geographic prevalence of HP...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.11769
更新日期:2020-01-31 00:00:00
abstract:INTRODUCTION:HIV causes progressive impairment of the cellular immune system leading to increased susceptibility to infectious agents. Parasitic infestations are common in HIV-infected patients and usually lead to diarrhoea. Few studies have addressed the issue of intestinal parasites among HIV-infected persons in Came...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.2757
更新日期:2013-02-15 00:00:00