Abstract:
INTRODUCTION:HIV causes progressive impairment of the cellular immune system leading to increased susceptibility to infectious agents. Parasitic infestations are common in HIV-infected patients and usually lead to diarrhoea. Few studies have addressed the issue of intestinal parasites among HIV-infected persons in Cameroon. This investigation was conducted in Douala, Cameroon, to assess the prevalence of gastrointestinal parasites in HIV-infected patients, taking into account their immune status and treatment course. METHODOLOGY:Stool and blood samples were collected from 201 HIV-positive patients for the investigation of intestinal pathogens and CD4+ counts. RESULTS:Fifty-six (27.9%) patients harbored pathogens. The most frequent pathogens were Candida spp. (14.9%), Cryptosporidium spp. (7.5%), Entamoeba histolytica, and Entamoeba dispar (3%). The presence of pathogens was significantly associated with diarrhoea, as they were found in 48.6% of diarrhoeic stools and 23.2% of non-diarrhoeic stools (OR = 3.14, p= 0.0018). Prevalence of pathogens and diarrhoea were significantly higher in patients with CD4+ counts ≤ 200 cells/µL (OR = 2.17, p = 0.0349 and OR = 8.46, p = 0.000019 respectively). CONCLUSIONS:This study highlights the need for investigating intestinal pathogens in HIV-infected patients presenting with diarrhoea, especially when their CD4+ counts are low.
journal_name
J Infect Dev Ctriesjournal_title
Journal of infection in developing countriesauthors
Lehman LG,Kangam L,Mbenoun ML,Zemo Nguepi E,Essomba N,Tonga C,Bilong Bilong CFdoi
10.3855/jidc.2757subject
Has Abstractpub_date
2013-02-15 00:00:00pages
137-43issue
2eissn
2036-6590issn
1972-2680journal_volume
7pub_type
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journal_title:Journal of infection in developing countries
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journal_title:Journal of infection in developing countries
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journal_title:Journal of infection in developing countries
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journal_title:Journal of infection in developing countries
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journal_title:Journal of infection in developing countries
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journal_title:Journal of infection in developing countries
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journal_title:Journal of infection in developing countries
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journal_title:Journal of infection in developing countries
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journal_title:Journal of infection in developing countries
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journal_title:Journal of infection in developing countries
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journal_title:Journal of infection in developing countries
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journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.3329
更新日期:2014-02-13 00:00:00
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journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.1470
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journal_title:Journal of infection in developing countries
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journal_title:Journal of infection in developing countries
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journal_title:Journal of infection in developing countries
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journal_title:Journal of infection in developing countries
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journal_title:Journal of infection in developing countries
pub_type: 杂志文章
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journal_title:Journal of infection in developing countries
pub_type: 杂志文章
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journal_title:Journal of infection in developing countries
pub_type: 杂志文章
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journal_title:Journal of infection in developing countries
pub_type: 杂志文章,评审
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journal_title:Journal of infection in developing countries
pub_type: 杂志文章
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journal_title:Journal of infection in developing countries
pub_type: 杂志文章
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journal_title:Journal of infection in developing countries
pub_type: 杂志文章
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journal_title:Journal of infection in developing countries
pub_type: 杂志文章
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