Abstract:
INTRODUCTION:The goal of this study was to evaluate whether any characteristics that are evident at presentation for urgent medical attention could be used to differentiate cases of H5N1 in the absence of viral testing. METHODOLOGY:Information about exposure to poultry, clinical signs and symptoms, treatments, and outcomes was abstracted from existing data in the global avian influenza registry (www.avianfluregistry.org) using standardized data collection tools for documented and possible cases of H5N1 infection who presented for medical attention between 2005-2011 during known H5N1 outbreaks in Azerbaijan, Indonesia, Pakistan and Turkey. RESULTS:Demography, exposure to poultry, and presenting symptoms were compared, with only the common symptoms of fever and headache presenting significantly more frequently in confirmed H5N1 cases than in possible cases. Reported exposure to infected humans was also more common in confirmed cases. In contrast, unexplained respiratory illness, sore throat, excess sputum production, and rhinorrhea were more frequent in possible cases. Overall, oseltamivir treatment showed a survival benefit, with the greatest benefit shown in H5N1 cases who were treated within two days of symptom onset (51% reduction in case fatality). CONCLUSION:Since prompt treatment with antivirals conferred a strong survival benefit for H5N1 cases, presumptive antiviral treatment should be considered for all possible cases presenting during an outbreak of H5N1 as a potentially life-saving measure.
journal_name
J Infect Dev Ctriesjournal_title
Journal of infection in developing countriesauthors
Zaman M,Gasimov V,Oner AF,Dogan N,Adisasmito W,Coker R,Bamgboye EL,Chan PK,Hanshaoworakul W,Lee N,Phommasack B,Touch S,Tsang O,Swenson A,Toovey S,Dreyer NAdoi
10.3855/jidc.3329subject
Has Abstractpub_date
2014-02-13 00:00:00pages
202-7issue
2eissn
2036-6590issn
1972-2680journal_volume
8pub_type
杂志文章abstract:INTRODUCTION:Sepsis is a major cause of childhood death worldwide. In developing countries, epidemiological data about sepsis is scarce. This study describes and compares the frequency of etiological agents and initial sites of infection in children with or without sepsis, identifying risk factors and assessing outcome...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.9257
更新日期:2017-09-05 00:00:00
abstract:INTRODUCTION:Men who have sex with men (MSM) are one of the key populations driving HIV/AIDS epidemic globally. To date, MSM is the only population in Ukraine where the prevalence and incidence of HIV is increasing. As HIV-positive MSM might feel uncomfortable to report homosexual intercourses as a possible mode of tra...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.11967
更新日期:2020-11-16 00:00:00
abstract:INTRODUCTION:Respiratory syncytial virus (RSV) is one of the most common causes of acute respiratory infections in all age groups especially under two years. The aim of this study was to investigate the frequency and clinical features of RSV in hospitalized children under two years of age with the diagnosis of lower re...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.8871
更新日期:2017-09-30 00:00:00
abstract:INTRODUCTION:Nosocomial pneumonia (NP) and ventilator associated pneumonia (VAP) occur most frequently in intensive care units (ICU). This study seeks to determine the etiological agents of NP and VAP along with their antibacterial susceptibility patterns, and to evaluate the factors contributing to patient mortality. ...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.1212
更新日期:2011-04-26 00:00:00
abstract:INTRODUCTION:In August 2011, Chittoor district authorities reported a cluster of suspected human anthrax cases to the Andhra Pradesh state surveillance unit. We investigated this cluster to confirm its etiology, describe its magnitude, identify potential risk factors, and make recommendations for preventing similar out...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.2635
更新日期:2012-10-19 00:00:00
abstract::Zika virus (ZIKV) infection is spreading rapidly within the Americas after originating from an outbreak in Brazil. We describe the current ZIKV infection epidemic in Brazil and the neurological symptoms arising. First cases of an acute exanthematic disease were reported in Brazil's Northeast region at the end of 2014....
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.8217
更新日期:2016-02-28 00:00:00
abstract:INTRODUCTION:This research aimed to determine the association of the combination of H. pylori infection and TP53 codon 72 polymorphism with non-cardia gastric cancer (GC) in Vietnam. METHODOLOGY:A total of 164 patients with non-cardia GC and 164 patients with peptic ulcer disease or functional dyspepsia in controls ma...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.11488
更新日期:2019-11-30 00:00:00
abstract:INTRODUCTION:The severity of urinary tract infection (UTI) produced by uropathogenic Escherichia coli (UPEC) is due to the expression of a wide spectrum of virulence genes. E. coli strains were divided into four phylogenetic groups (A, B1, B2 and D) based on their virulence genes. The present study aimed to assess the ...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.7903
更新日期:2017-01-30 00:00:00
abstract:BACKGROUND:Streptococcus pneumoniae is a major human pathogen. The emergence of penicillin resistant strains since the 1970s has been life threatening and the evolution of the bacteria have enabled itself to develop resistance to many other antibiotics such as the macrolides and the fluoroquinolones. This study aims to...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.262
更新日期:2008-06-01 00:00:00
abstract:INTRODUCTION:Although omphalitis (umbilical infections) among newborns is common and a major cause of neonatal deaths in developing countries, information on its burden and etiology from community settings is lacking. This study aimed to determine the incidence and etiology of omphalitis in newborns in high neonatal mo...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章,评审
doi:10.3855/jidc.1229
更新日期:2011-12-13 00:00:00
abstract:INTRODUCTION:Urinary Tract Infections (UTIs) is one of the most common infections worldwide. UTIs remain a challenge to the healthcare system because of the emergence of antimicrobial resistance. The aim of this study is to report the most common UTI-causative organisms associated with the emergence of antimicrobial re...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.9517
更新日期:2018-04-30 00:00:00
abstract:INTRODUCTION:Previous sentinel surveys of HIV in Nigeria studied pregnant women attending antenatal care, thereby omitting other important high-risk groups. We therefore investigated the prevalence of HIV/AIDS in low- and high-risk populations in the state of Plateau, Nigeria. METHODOLOGY:Blood samples were collected ...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.1872
更新日期:2012-12-15 00:00:00
abstract::Ochrobactrum and Brucella are genetically related genera of the family Brucellaceae, sharing 98.8% rRNA similarity. Because of their phenotypic similarity, Ochrobactrum can be miscoded as Brucella by automated identification systems. The misidentification on blood cultures (BCs) of B. suis as O. anthropi by the VITEK ...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.7532
更新日期:2016-04-28 00:00:00
abstract:INTRODUCTION:Plasmid-mediated quinolone resistance, which complicates treatment, has been increasingly identified in Escherichia coli isolates worldwide. The purpose of this study was to identify the plasmid-mediated qnrA and qnrB genes among the quinolone-resistant Escherichia coli isolated from urinary tract infectio...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.3746
更新日期:2014-07-14 00:00:00
abstract:BACKGROUND:Helicobacter pylori is one of the most common causes of peptic ulcer disease worldwide and a major cause of chronic superficial gastritis leading to atrophy of gastric glands. METHODOLOGY:A total of 60 patients suffering from gastric disease due to H. pylori infection were evaluated. Endoscopy was performed...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.194
更新日期:2008-10-01 00:00:00
abstract:INTRODUCTION:This study sought to identify the association of antibiotic prescribing and the risk of antibiotic-associated diarrhoea (AAD) in Korle Bu Teaching Hospital (KBTH) in Ghana. METHODOLOGY:Patients from the Male Urology Ward and Treatment Room of the Surgical Department of KBTH were followed up over three mon...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.11259
更新日期:2020-08-31 00:00:00
abstract:INTRODUCTION:Infants represent an important risk group for influenza associated hospitalizations and mortality. This study evaluated the clinical presentations, hospitalization course and outcome of infants hospitalized with the pandemic influenza A H1N1 [Influenza A(H1N1)pdm09] in relation to their previous health sta...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.2339
更新日期:2012-08-21 00:00:00
abstract:INTRODUCTION:Acquisition of sexually transmitted infections (STIs) is an epidemiological marker of high-risk sexual behavior in HIV-infected patients. We assessed the prevalence of STIs among patients attending an HIV care and support centre. METHODOLOGY:From January to August 2009, we assessed socio-demographic varia...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.1754
更新日期:2012-03-12 00:00:00
abstract:INTRODUCTION:Infections caused by multidrug-resistant bacteria are increasingly common and represent a serious problem for public health. Staphylococcus aureus is one of the major agents of infections, and methicillin-resistant S. aureus (MRSA) has spread worldwide. The aim of this study was to phenotypically and genot...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.7887
更新日期:2016-12-30 00:00:00
abstract:INTRODUCTION:Salmonella infections are increasing worldwide, but there are few reports on Salmonella surveillance in African countries and other developing countries. This has made it difficult to estimate the actual burden of salmonellosis, especially in Africa. This study was conducted in a neglected Northern Region ...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.3548
更新日期:2013-10-15 00:00:00
abstract:INTRODUCTION:Human co-infection with Plasmodium falciparum and helminthes is ubiquitous throughout Africa. This study aimed to determine the co-infections of Plasmodium falciparum infection in HIV and intestinal parasitic infections, and their immunological distribution, in Benin City, Nigeria. METHODOLOGY:A total of ...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.1889
更新日期:2012-05-14 00:00:00
abstract:INTRODUCTION:This study aimed to determine the resistance patterns of Escherichia coli (E. coli) in Mexico to several antibiotics and research some therapeutic options. METHODOLOGY:Positive cultures for E. coli isolated from bronchial secretions, urine, central catheter, blood, and infected wounds in the Culiacan Gene...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.1525
更新日期:2012-02-13 00:00:00
abstract:INTRODUCTION:Saudi Arabia (SA) experienced a highly pathogenic avian influenza (HPAI) H5N1 outbreak in domesticated birds in 2007. METHODOLOGY:Forty-three hemagglutinin (HA) and 41 neuraminidase (NA) genes of HPAI H5N1 viruses were sequenced and phylogenetic analyses of completely sequenced genes were performed to com...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.6546
更新日期:2015-11-30 00:00:00
abstract:INTRODUCTION:Salmonella enterica serotype Kentucky was isolated from septic poultry in Nigeria. The objective of this study was to characterize this isolate by screening for SGI1 and hyper-virulence. METHODOLOGY:The strain was characterized by identification of Salmonella genomic island 1 (SGI1) through a PCR assay an...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.1988
更新日期:2012-06-15 00:00:00
abstract:INTRODUCTION:Rickettsia sibirica mongolitimonae was recently reported as a common rickettsiosis in France. Current serological evidence suggests the presence of scrub typhus and spotted fever group rickettsiosis in Sri Lanka. We detected a human case of R. sibirica mongolitimonae in Sri Lanka. METHODOLOGY:A skin biops...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.8743
更新日期:2017-09-05 00:00:00
abstract:INTRODUCTION:The efficacy of non-adjuvanted seasonal influenza vaccine in young children is considered to be suboptimal. This study compared the safety and immunogenicity profiles of MF59-adjuvanted, trivalent, influenza vaccine (ATIV) and non-adjuvanted, trivalent, influenza vaccine (TIV) in Guatemalan children (N = 3...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.3855/jidc.4594
更新日期:2014-09-12 00:00:00
abstract:INTRODUCTION:In low- and middle-income countries such as India, private pharmacies play an important role in medical treatments, offering advice for common illnesses such as diarrhea and respiratory tract infections. There is a need to explore the details of the dispensing practices at the private pharmacies in low- an...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.5694
更新日期:2015-05-18 00:00:00
abstract::Coronavirus disease 2019 (COVID-19) represents a severe global public health threat. Caused by SARS-Cov-2, COVID-19 is characterized by high transmission rate that correlates with high viral load. The full clinical spectrum of the illness, the prevalence rates of mild symptomatic and asymptomatic cases, and the case f...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章,评审
doi:10.3855/jidc.12805
更新日期:2020-09-30 00:00:00
abstract:INTRODUCTION:The aim of this study was to assess tuberculosis (TB) knowledge, attitudes, and practices in both the general population and risk groups in Thailand. METHODOLOGY:In a cross-sectional survey, a general population (n = 3,074) and family members of a TB patient (n = 559) were randomly selected, using stratif...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.6963
更新日期:2016-08-02 00:00:00
abstract:INTRODUCTION:We investigated the frequency of H274Y-positive swine-origin 2009 A (H1N1) influenza virus outbreak in Thailand during May-August 2009. METHODOLOGY:This study sought to find Oseltamivir resistance mutation H274Y by using pyrosequencing. RESULTS:From 8,710 real-time RT-PCR swine-origin 2009 A(H1N1) influ...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.1197
更新日期:2011-05-28 00:00:00