Abstract:
INTRODUCTION:Essential oils have been used since ancient times and are known for their anti-inflammatory, anti-depressive, antiseptic, antifungal and antimicrobial properties. METHODOLOGY:in this study the antimicrobial activity of two essential oils from Melaleuca alternifolia and Thymus vulgaris-red thyme geraniol was tested against 16 multidrug-resistant P. aeruginosa strains from infected hip implants as well as the "in vitro" cytotoxic activity on normal human Wong-Kilbourne derivative (WKD) cells. RESULTS:Thymus vulgaris-red thyme geraniol showed lower antimicrobial activity when compared to Melaleuca alternifolia. All tested oils were cytotoxic at concentrations lower than 0.12%. CONCLUSION:Increase in drug resistance and lack of new antibiotics may encourage the development of natural treatments together with higher concern on environmental issues and natural lifestyle.
journal_name
J Infect Dev Ctriesjournal_title
Journal of infection in developing countriesauthors
Amorese V,Donadu M,Usai D,Sanna A,Milia F,Pisanu F,Molicotti P,Zanetti S,Doria Cdoi
10.3855/jidc.10988subject
Has Abstractpub_date
2018-11-30 00:00:00pages
996-1001issue
11eissn
2036-6590issn
1972-2680journal_volume
12pub_type
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