Abstract:
INTRODUCTION:Shigellosis is a major public health concern worldwide. This study intended to assess the baseline genotyping data among local Shigella sonnei strains spanning over five years. METHODOLOGY:Fifty non-repeat clinical strains of S. sonnei isolated from stools of patients in different hospitals in Nanjing, China, were studied. Three subtyping tools, pulsed-field gel electrophoresis (PFGE), multi-locus sequence typing (MLST), and multi-locus variable-number tandem-repeat (VNTR) analysis (MLVA), were used for routinely subtyping local S. sonnei. RESULTS:DNA sequencing only identified two sequence types (STs) among the 50 isolates in the MLST profiles, whereas PFGE and MLVA both showed suitable discriminatory power and yielded 19 and 30 different patterns, respectively. The major PFGE pattern comprised 21 strains isolated from different years. A total of four complexes were identified by MLVA, with the isolates differing by a single locus (single-locus variants). CONCLUSIONS:The S. sonnei strains circulating in Nanjing, China, in 2007-2011 originated from different clones with a degree of diversity. Most of the clones were closely related to each other. Overall, the strains were distinguishable by PFGE and MLVA. MLVA based on eight selected VNTR loci represented a more favorable degree of discrimination than did PFGE and may be a reliable complement for PFGE for routine subtyping of S. sonnei. The problems of MLST in subtyping regarding S. sonnei were also demonstrated.
journal_name
J Infect Dev Ctriesjournal_title
Journal of infection in developing countriesauthors
Cheng T,Shi X,Yong W,Wang J,Xie G,Ding Jdoi
10.3855/jidc.4933subject
Has Abstractpub_date
2014-12-15 00:00:00pages
1525-32issue
12eissn
2036-6590issn
1972-2680journal_volume
8pub_type
杂志文章abstract::Leclercia adecarboxylata was isolated in pure culture from a peritonsillar and lateral pharyngeal abscess in an immunocompetent host. To our knowledge, this is the first case of infection caused by this microorganism being found in an odontogenic area of the head and neck. ...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.2651
更新日期:2013-01-15 00:00:00
abstract:INTRODUCTION:Infections caused by multidrug-resistant bacteria are increasingly common and represent a serious problem for public health. Staphylococcus aureus is one of the major agents of infections, and methicillin-resistant S. aureus (MRSA) has spread worldwide. The aim of this study was to phenotypically and genot...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.7887
更新日期:2016-12-30 00:00:00
abstract:INTRODUCTION:Helicobacter pylori cause damage to gastric epithelial cells and alterations in the p53 gene that lead to cancer development. This study aimed to determine the correlation of p53 expression with H. pylori using immunohistochemistry, RFLP-PCR, and histopathology. METHODOLOGY:Gastric biopsy samples from gas...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.2993
更新日期:2013-09-16 00:00:00
abstract:BACKGROUND:This work demonstrates successful propagation of HCV in HepG2 and human blood cells as well as viral shedding into their culture media. The influence of Schistosoma mansoni crude soluble egg antigens (SEA) on the rate of viral propagation in both mammalian cells was also monitored. METHODOLOGY:HepG2 cells w...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.522
更新日期:2010-05-01 00:00:00
abstract:INTRODUCTION:Rotavirus (RV) is the leading cause of severe diarrhea-associated morbidity and mortality among children worldwide. Limited data exist on the epidemiology and burden of rotavirus gastroenteritis in Armenia. The purpose of this study is to estimate the economic losses and describe the epidemiological charac...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.10883
更新日期:2019-04-30 00:00:00
abstract:INTRODUCTION:Anti-hepatitis B core antibody (Anti-HBc) alone is defined as the presence of anti-HBc in the absence of HBsAg and anti-HBs. The significance of this serological pattern as a predicting factor for occult hepatitis B virus (HBV) infection remains largely unknown. This study aimed to assess the significance ...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.728
更新日期:2010-10-28 00:00:00
abstract:INTRODUCTION:Despite tremendous progress made toward elimination, measles continues to pose a great threat to the health of children in developing countries. The objective of this study was to summarize and analyze the clinical characteristics and treatment experience of serious complications of measles pneumonia in ch...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.6534
更新日期:2015-10-29 00:00:00
abstract:INTRODUCTION:Bacille Calmette-Guerin (BCG) vaccination remains a routine immunization in primary care in tuberculosis (TB)-endemic areas, though several studies found that its efficacy was inconclusive. Natural resistance-asociated machrophage protein 1 (NRAMP1) polymorphism has been shown to result in higher susceptib...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.5047
更新日期:2015-01-15 00:00:00
abstract::Pegylated interferon (PEG-IFN) alpha and ribavirin therapy has become the standard treatment in chronic hepatitis C virus (HCH)-infected patients. While thrombocytopenia associated with IFN use is frequently observed among these patients, autoimmune thrombocytopenia is one of the rarely observed adverse effects. In th...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.559
更新日期:2009-09-15 00:00:00
abstract:INTRODUCTION:HIV causes progressive impairment of the cellular immune system leading to increased susceptibility to infectious agents. Parasitic infestations are common in HIV-infected patients and usually lead to diarrhoea. Few studies have addressed the issue of intestinal parasites among HIV-infected persons in Came...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.2757
更新日期:2013-02-15 00:00:00
abstract:INTRODUCTION:There is limited knowledge about the associations of Helicobacter pylori (H. pylori) infections in developing countries. This study aimed to determine the current prevalence and associations of H. pylori infection with breastfeeding practices, nutritional status, and recurrent abdominal pain (RAP) in a gro...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.3196
更新日期:2014-04-15 00:00:00
abstract:BACKGROUND:Research on the effects of corticosteroids in bacterial meningitis (BM) yielded conflicting results. While some studies reveal that corticosteroids improve the outcomes in BM treatments, others provide strong evidence that patients do not profit from this treatment. We investigated the factors that may impac...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.51
更新日期:2009-12-14 00:00:00
abstract::Guangxi is a province of China endemic for enteric fever. Salmonella enterica serovar Paratyphi A has been found to be causing more and more enteric fever episodes in the last 10 years, evident not only from routine surveillance but also from prospective population-based surveillance. The prevalent pattern of paratyph...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.223
更新日期:2008-08-30 00:00:00
abstract:INTRODUCTION:Acinetobacter baumannii is a pathogen that is causing concern due to its high genetic elasticity, allowing it to show high rates of antibiotic resistance and to express a wide range of virulence determinants. Several studies are aimed towards targeting the virulence of A. baumannii as an adjunct to antibio...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.9956
更新日期:2018-02-22 00:00:00
abstract:INTRODUCTION:Sexually transmitted infections (STI) are a major public health, social, and economic problem leading to morbidity, mortality, and stigma. This study was conducted to determine the prevalence of STIs, investigate behavioral risk factors and the relationship between the STIs/HIV and demographic factors. ME...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.5964
更新日期:2015-04-15 00:00:00
abstract:INTRODUCTION:The goal of this study was to evaluate whether any characteristics that are evident at presentation for urgent medical attention could be used to differentiate cases of H5N1 in the absence of viral testing. METHODOLOGY:Information about exposure to poultry, clinical signs and symptoms, treatments, and out...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.3329
更新日期:2014-02-13 00:00:00
abstract:INTRODUCTION:Although omphalitis (umbilical infections) among newborns is common and a major cause of neonatal deaths in developing countries, information on its burden and etiology from community settings is lacking. This study aimed to determine the incidence and etiology of omphalitis in newborns in high neonatal mo...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章,评审
doi:10.3855/jidc.1229
更新日期:2011-12-13 00:00:00
abstract:BACKGROUND:Helicobacter pylori is one of the most common causes of peptic ulcer disease worldwide and a major cause of chronic superficial gastritis leading to atrophy of gastric glands. METHODOLOGY:A total of 60 patients suffering from gastric disease due to H. pylori infection were evaluated. Endoscopy was performed...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.194
更新日期:2008-10-01 00:00:00
abstract:INTRODUCTION:Human papillomavirus (HPV) infection is typically critical in the oncogenesis of cervical cancer. However, available HPV detection kits differ in their ability and sensitivity to detect various types of HPV, and this variability has led to inconsistencies in the reporting of the geographic prevalence of HP...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.11769
更新日期:2020-01-31 00:00:00
abstract::A novel influenza A H1N1 virus of swine origin is responsible for the influenza epidemic affecting Mexico, the United States of America (USA), and 39 other countries. While the origin of this emerging pathogen remains uncertain, an increase in the reported incidence of respiratory diseases was noted during March 2009 ...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章,评审
doi:10.3855/jidc.238
更新日期:2009-06-01 00:00:00
abstract:INTRODUCTION:Miscarriage is one of the most common adverse pregnancy outcomes. The aim of this study was to investigate the relationship between miscarriage in humans and infections caused by zoonotic bacteria and genital pathogens. METHODOLOGY:Cervicovaginal swabs and placenta samples from 132 women with miscarriage ...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.9829
更新日期:2019-05-31 00:00:00
abstract::Zika virus (ZIKV) is an emerging arbovirus of the Flaviviridae family and is related to dengue, Chikungunya, West Nile, yellow fever, and Japanese encephalitis viruses. ZIKV was first discovered in Uganda in 1947. Different species of mosquito from the Aedes genus, mainly A. aegypti and A. albopictus are the vectors r...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章,评审
doi:10.3855/jidc.8350
更新日期:2016-03-31 00:00:00
abstract:INTRODUCTION:Pancreatitis is a rare complication of hemorrhagic fever with renal syndrome (HFRS). The causative agents of HFRS are hantaviruses, which belong to the genus Hantavirus, family Bunyaviridae. The purpose of this study was to evaluate cases of acute pancreatitis (AP) in patients with HFRS at the Service of I...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.9567
更新日期:2017-12-10 00:00:00
abstract:INTRODUCTION:Livestock are nowadays considered potent reservoirs of multi drug resistance. Enteric resistant organisms in animals can be transmitted to humans and be causative agents of infections with therapeutic challenges. The aim of this study is to determine the prevalence of multi drug resistant organisms in Leba...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.10024
更新日期:2018-02-22 00:00:00
abstract::A clinical case of infection caused by Fasciolopsis buski in a 24 weeks pregnant woman from Vietnam affected by systemic lupus erythematosus (SLE) is reported here. On 22 February 2012 the patient was admitted to Hue Hospital in Hue, Vietnam, with a diagnosis of general illness and suspected acute anaemia. Laboratory ...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.7017
更新日期:2015-07-04 00:00:00
abstract:INTRODUCTION:Antimicrobial resistance (AR) is a multifaceted problem of global significance. In addition to developing new drugs and using antimicrobial guidelines, it is essential that health professionals understand all aspects of the problem and the most effective ways to handle it. This study evaluated pharmacists'...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.4853
更新日期:2015-03-15 00:00:00
abstract:INTRODUCTION:A country's development level is measured with a quantitative parameter called the human development index (HDI). The present study researched the effects of HDI parameters (such as healthcare standards, income, and education level) on the incidence of tuberculosis. METHODOLOGY:HDI data of 36 provinces of...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.8101
更新日期:2016-11-24 00:00:00
abstract:INTRODUCTION:Invasive fungal infection (IFI) is a major cause of morbidity and mortality in allogeneic hematopoietic stem cell transplantation (allo-HSCT) recipients. A previous history of IFI is not an absolute contraindication for allo-HSCT, particularly in the era of secondary antifungal prophylaxis (SAP). Prompt di...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.9961
更新日期:2018-09-30 00:00:00
abstract:INTRODUCTION:The etiological association of Helicobacter pylori with gastric ulcer (GU), gastric cancer (GC), and duodenal ulcer (DU) is well-known. Understanding the epidemiology of H. pylori facilitates the estimation of disease burden in a certain population. This study presents the diversity of H. pylori genotypes ...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.2942
更新日期:2013-03-14 00:00:00
abstract:BACKGROUND:Salmonella enterica serovars Typhi and Paratyphi A are human host-restricted pathogens. Therefore, there is no small susceptible animal host that can be used to assess the virulence and safety of vaccine strains derived from these Salmonella serovars. However, infant mice have been used to evaluate virulenc...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.1218
更新日期:2010-11-24 00:00:00