Abstract:
INTRODUCTION:Hand, foot, and mouth disease (HFMD) is a common childhood illness caused by enteroviruses. A passive surveillance system has been implemented in Shanghai Pudong since 2008 and etiology surveillance since 2009.We characterized the epidemiology and the etiology of HFMD in Pudong from 2008-2013. METHODOLOGY:Health care providers were required to report any clinically diagnosed HFMD to Pudong District Center for Disease Control and Prevention. For all severe cases and randomly selected mild HFMD cases, throat or rectal swabs or feces were collected for enterovirus detection by real time reverse transcription polymerase chain reaction. RESULTS:A total of 50,149 cases were reported, with average 8,508 per year (range: 3,577-13,202) and average incidence of 167.5/100,000 persons (range: 81.4-254.1/100,000 persons). HFMD was more likely to occur in children under five years of age (85.6%), while severe cases were more likely to happen in children under three years of age (63.9%). Every year in May or June, HFMD peaked in the region; two peaks were observed from 2011 to 2013.The most common etiologic agents are EV71 and CA16.Different types of enterovirus circulate in different years. EV71 was the predominant pathogen in severe cases. The proportions of EV71 in severe cases was higher than in mild cases at the children's medical center (p<0.001). CONCLUSIONS:HFMD remains an important public health issue in Shanghai. HFMD pathogen surveillance is required for more types of enteroviruses besides EV71 and CA16, which would give a better picture of the etiology of HFMD.
journal_name
J Infect Dev Ctriesjournal_title
Journal of infection in developing countriesauthors
Fu Y,Sun Q,Liu B,Xu H,Wang Y,Zhu W,Pan L,Zhu Ldoi
10.3855/jidc.6118subject
Has Abstractpub_date
2016-06-30 00:00:00pages
612-8issue
6eissn
2036-6590issn
1972-2680journal_volume
10pub_type
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journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.6546
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journal_title:Journal of infection in developing countries
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journal_title:Journal of infection in developing countries
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journal_title:Journal of infection in developing countries
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journal_title:Journal of infection in developing countries
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journal_title:Journal of infection in developing countries
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journal_title:Journal of infection in developing countries
pub_type: 杂志文章,评审
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journal_title:Journal of infection in developing countries
pub_type: 杂志文章,多中心研究
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journal_title:Journal of infection in developing countries
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journal_title:Journal of infection in developing countries
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journal_title:Journal of infection in developing countries
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doi:10.3855/jidc.4450
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journal_title:Journal of infection in developing countries
pub_type: 杂志文章
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journal_title:Journal of infection in developing countries
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journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.7800
更新日期:2017-04-30 00:00:00
abstract:INTRODUCTION:Pneumocystis jirovecii (PJ) pneumonia (PJP) is an important opportunistic infection affecting various types of immunocompromised patients and is associated with an increased risk of mortality. PJ is a unique fungal pathogen which is increasingly common and maybe associated with a higher mortality rate in p...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
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更新日期:2018-10-31 00:00:00
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journal_title:Journal of infection in developing countries
pub_type: 杂志文章
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journal_title:Journal of infection in developing countries
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journal_title:Journal of infection in developing countries
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journal_title:Journal of infection in developing countries
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journal_title:Journal of infection in developing countries
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