Abstract:
INTRODUCTION:There is an urgent need for affordable point-of-care diagnostics for the differentiation of febrile illnesses and the confirmation of typhoid in endemic countries. METHODOLOGY:Blood samples were collected from febrile patients with clinical suspicion of typhoid and screened for typhoid fever using the Widal and Typhi Dri Dot tests, while stool and blood samples were screened for Salmonella Typhi using the culture method as well as PCR as a confirmatory test. RESULTS:A high proportion of febrile patients from Lagos with clinical suspicion of typhoid fever reacted positively in a simple and rapid latex agglutination assay for typhoid fever, indicating that this illness is a common and presumably under-diagnosed health problem in this metropolis. Seropositivity was 19.2% in the rapid test compared with 22.9% in the classical Widal test. The confirmation of typhoid in these seropositive patients appeared cumbersome because of negative blood cultures and low DNA yield in molecular testing. A review of the literature revealed that in Nigeria seroprevalence rates can be high in the normal population and that pathogens other than S. Typhi are often isolated from the blood of seropositive febrile patients. CONCLUSION:The simplicity and the relatively high specificity (97.8%) of the rapid test as determined in a study performed in Indonesia calls for a further validation of this promising test for use in Africa.
journal_name
J Infect Dev Ctriesjournal_title
Journal of infection in developing countriesauthors
Smith SI,Bamidele M,Fowora M,Goodluck HT,Omonigbehin EA,Akinsinde KA,Fesobi T,Pastoor R,Abdoel TH,Smits HLdoi
10.3855/jidc.1836subject
Has Abstractpub_date
2011-07-27 00:00:00pages
520-6issue
7eissn
2036-6590issn
1972-2680journal_volume
5pub_type
杂志文章abstract:INTRODUCTION:Salmonella is well recognized as an aetiological agent of gastrointestinal and diarrhoeal disease. Salmonella enterica serotype Enteritidis (Salmonella Enteritidis) is one of the commonest serotypes associated with foodborne illness. In South Africa, we compared Salmonella Enteritidis strains isolated from...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.5393
更新日期:2014-12-15 00:00:00
abstract:INTRODUCTION:Acquisition of sexually transmitted infections (STIs) is an epidemiological marker of high-risk sexual behavior in HIV-infected patients. We assessed the prevalence of STIs among patients attending an HIV care and support centre. METHODOLOGY:From January to August 2009, we assessed socio-demographic varia...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.1754
更新日期:2012-03-12 00:00:00
abstract:INTRODUCTION:In some developing countries, tuberculosis and brucellosis, which are commom causes of spinal infections, are still common infectious diseases. However, co-occurrence of spinal tuberculosis and brucellosis is rare. METHODOLOGY:We report a case a 47-year-old male engaged in aquaculture with a medical histo...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.12647
更新日期:2020-10-31 00:00:00
abstract:INTRODUCTION:Coronary heart disease and its risk factors depend on genetic characteristics, behaviors, and habits, all of which vary in different regions. The use of antiretroviral therapy (ARV) has increased the survival of people living with HIV/AIDS (PLWHA), who begin to present mortality indicators similar to the g...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.5867
更新日期:2015-09-27 00:00:00
abstract:INTRODUCTION:Detection of heterogeneous vancomycin-intermediate Staphylococcus aureus (hVISA) is currently problematic. Although the population analysis profile with area under the curve (PAP-AUC) is the gold standard for detecting hVISA strains, this method is time consuming. This study aimed to induce vancomycin non-...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.5059
更新日期:2015-02-19 00:00:00
abstract::Brucellosis is an endemic disease in developing countries. The most commonly observed complications include bone-joint involvement, particularly sacroiliitis and spondylitis. Epidural abscesses caused by brucellosis are a rare complication. We describe the case of a 33-year-old man presenting with high fever, back pai...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.1470
更新日期:2011-05-28 00:00:00
abstract:INTRODUCTION:The aim of this study was to assess tuberculosis (TB) knowledge, attitudes, and practices in both the general population and risk groups in Thailand. METHODOLOGY:In a cross-sectional survey, a general population (n = 3,074) and family members of a TB patient (n = 559) were randomly selected, using stratif...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.6963
更新日期:2016-08-02 00:00:00
abstract:INTRODUCTION:Giardiasis is a human health concern worldwide, especially among schoolchildren. Giardia duodenalis genotypes A and B are infective to humans, but their zoonotic potential remains controversial. In Mexico, the most prevalent genotype is A, but B was also detected in southeastern Mexico. In Sinaloa state, n...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.8223
更新日期:2017-02-28 00:00:00
abstract:INTRODUCTION:This research aimed to determine the association of the combination of H. pylori infection and TP53 codon 72 polymorphism with non-cardia gastric cancer (GC) in Vietnam. METHODOLOGY:A total of 164 patients with non-cardia GC and 164 patients with peptic ulcer disease or functional dyspepsia in controls ma...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.11488
更新日期:2019-11-30 00:00:00
abstract:INTRODUCTION:Assays based on DNA amplification can provide information that contributes to the initial management of patients with leptospirosis. However, these have not been adopted in Uruguay. Our aim was to evaluate the performance of the lipL32 real-time PCR (qPCR) for diagnosis of leptospirosis. METHODOLOGY:We an...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.4110
更新日期:2013-12-15 00:00:00
abstract:INTRODUCTION:Pancreatitis is a rare complication of hemorrhagic fever with renal syndrome (HFRS). The causative agents of HFRS are hantaviruses, which belong to the genus Hantavirus, family Bunyaviridae. The purpose of this study was to evaluate cases of acute pancreatitis (AP) in patients with HFRS at the Service of I...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.9567
更新日期:2017-12-10 00:00:00
abstract:INTRODUCTION:A one of the step towards achieving TB related targets is to ensure early and quality diagnosis of TB in national laboratories. WHO recommends that all national reference laboratories in TB burden countries strive to reach accreditation by 2025, based on ISO15189:2012 quality management system standard. To...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.10935
更新日期:2019-05-16 00:00:00
abstract:INTRODUCTION:Dengue virus (DENV) infection is currently a major cause of morbidity in the world, and its incidence has mainly increased during the last years in Latin America, including Paraguay. The objective of this study was to compare the clinical and laboratory findings of dengue and assess whether the serotype is...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.11584
更新日期:2019-12-31 00:00:00
abstract:INTRODUCTION:Miscarriage is one of the most common adverse pregnancy outcomes. The aim of this study was to investigate the relationship between miscarriage in humans and infections caused by zoonotic bacteria and genital pathogens. METHODOLOGY:Cervicovaginal swabs and placenta samples from 132 women with miscarriage ...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.9829
更新日期:2019-05-31 00:00:00
abstract:INTRODUCTION:Inappropriate use of antibiotics is recognised as a leading cause of antibiotic resistance. Little is known about antibiotic prescribing practices at public health facilities in low- and middle-income countries. We examined patterns of antibiotic prescribing in public health facilities in Nepal and explore...
journal_title:Journal of infection in developing countries
pub_type: 社论,多中心研究
doi:10.3855/jidc.11817
更新日期:2020-01-31 00:00:00
abstract:INTRODUCTION:There is a known connection between periodontitis and atherosclerosis and the presence of periopathogens in blood vessels. However, changes of the oral microflora related to the aging process and its possible effects on atherosclerosis, have yet to be analyzed. The aim of this study was to assess temporal ...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.10980
更新日期:2018-12-31 00:00:00
abstract:INTRODUCTION:Intestinal and extraintestinal infections by Aeromonas spp., remain controversial, due to the existence of healthy carriers of Aeromonas spp. In children under five years old, the diarrhea of infectious origin constitutes the second cause of mortality and remains a major concern for public health. The aim ...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.12966
更新日期:2020-10-31 00:00:00
abstract:INTRODUCTION:We assessed the influence of a result-based financing (RBF) model, which included incentives for Primary Healthcare facilities on TB treatment outcomes. METHODOLOGY:We compared TB patients > 17 years and their treatment outcomes among those who did and did not benefit from RBF-model in 14 districts of Ode...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.11292
更新日期:2019-07-31 00:00:00
abstract:BACKGROUND:Salmonella spp. are recognized as some of the most common causes of enteritis worldwide. This study aimed to identify clinically isolated S. Typhimurium in western Kenya and to assess antimicrobial resistance profiles and strain inter-relatedness. METHODS:The study was performed in rural Maseno, Nyanza prov...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.610
更新日期:2009-10-26 00:00:00
abstract:INTRODUCTION:The present study was conducted to evaluate the prevalence of Trichuris spp. and other intestinal parasitic infections in owned cats on St. Kitts. METHODOLOGY:The feces of 41 non-feral cats (23 indoor only; 18 indoor/outdoor) were examined for the presence of Trichuris spp. eggs. RESULTS:Nine (22%) of th...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.5778
更新日期:2015-01-15 00:00:00
abstract:INTRODUCTION:Mastitis is one of the most frequent and costly disease in cattle. We studied milk samples from cattle with mastitis from farms in Kosovo to identify mastitis-causing pathogens and possible effective antibiotics. Our ultimate goal is to help implement adequate antibiotic management and treatment practices ...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.7912
更新日期:2016-10-31 00:00:00
abstract:INTRODUCTION:Tuberculosis (TB) continues to be a public health problem globally. The burden is further exacerbated in developing countries like Nigeria, by poor diagnosis, management and treatment, as well as rapid emergence of drug-resistant TB. This study was conducted to evaluate the prevalence of drug-resistant TB,...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.12736
更新日期:2020-09-30 00:00:00
abstract:INTRODUCTION:Antimicrobial stewardship practices are crucial for the regular surveillance to change the antimicrobial policy. This study was conducted to decide the prevalence of common bacteria and their antibiogram regarding antimicrobial stewardship program within one year, at the regional and district, Stanger hosp...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.10685
更新日期:2019-08-31 00:00:00
abstract::Increasing antimicrobial resistance to key antibiotics in Helicobacter pylori has become a main cause of treatment failures in many countries, including Vietnam. For this reason it is advisable to perform antimicrobial sensitivity tests to provide more focused regimens for H. pylori eradication. However, this approach...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章,评审
doi:10.3855/jidc.6942
更新日期:2015-07-04 00:00:00
abstract::An unusual case of malaria presented with gastroenteritis and bloody diarrhoea in a 46-year-old male. The patient was a non-Saudi resident of Makkah, Saudi Arabia. Fever was not the presenting complaint, and the patient had not experienced any chills or sweating. He gave history of recent travel to Pakistan. Initial l...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.58
更新日期:2009-03-01 00:00:00
abstract::The increasing prevalence of foodborne diseases observed in developing countries has been linked to a rise in the consumption of raw foods. However, unlike the classical pathogens that are commonly implicated in foodborne illnesses, members of the genus Acinetobacter are rarely associated with diarrheal disease, proba...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章,评审
doi:10.3855/jidc.8418
更新日期:2017-02-28 00:00:00
abstract:INTRODUCTION:Intestinal parasitic infection has been a significant problem in HIV patients, worldwide. In this study, we aimed to measure the prevalence and identify the factors associated with intestinal parasitic infection in people infected with HIV and attending National Public Health Laboratory in Kathmandu, Nepal...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.2785
更新日期:2013-07-15 00:00:00
abstract:INTRODUCTION:Leptospirosis is a zoonotic disease caused by the spirochete of genus Leptospira with widespread distribution in tropical, subtropical and temperate zones. Leptospirosis is often confused with other febrile illnesses including jaundice, dengue, and malaria. Generally, the disease is often underdiagnosed or...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.9545
更新日期:2018-01-31 00:00:00
abstract:INTRODUCTION:Norovirus is not usually investigated in diarrheal patients in Bangladesh which may account for the many cases where no pathogens are identified. METHODOLOGY:Stool specimens collected from diarrheal patients from three hospitals in Bangladesh during 2011 were investigated for norovirus RNA using real-time...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.2944
更新日期:2013-11-15 00:00:00
abstract:BACKGROUND:The prevalence of multi-infections with helminthes, protozoans and Campylobacter spp. in Guatemalan children is a reflection of differences in the risk factors related to pathogen transmission. METHODOLOGY:Two hundred and eighty-nine fecal samples were collected from children of the Guatemalan highlands and...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.41
更新日期:2009-04-30 00:00:00