Abstract:
INTRODUCTION:Use of herbal remedies among HIV-infected individuals in Africa increased in the past decade, mainly due to traditional beliefs and at times inconsistent access to antiretroviral drugs. In Zimbabwe, accessibility and availability of antiretroviral drugs has increased in recent years; however, the use of herbal remedies remains high. This study was conducted to determine the impact of concomitant use of herbal remedies with antiretroviral drugs on adverse events and on quality of life. METHODOLOGY:A convenient sample of HIV positive patients at Parirenyatwa group of hospitals' Family Care Clinic (Harare, Zimbabwe) was enrolled. A questionnaire was used to collect data on the adverse event experiences of the patients using herbal remedies for their HIV, as well as the types of herbal remedy used. Quality of life index was measured using an HIV/AIDS targeted quality of life (HAT-QOL) tool developed by the World Health Organization. RESULTS:Abdominal pain (odds ratio = 2.7, p-value = 0.01) and rash (odds ratio = 2.5, p-value = 0.02) had significant associations with using herbal remedies during antiretroviral therapy. Improved quality of life index was not significantly associated with herbal remedy use during antiretroviral therapy. CONCLUSIONS:There is evidence to suggest that some traditional herbal remedies used in Zimbabwe may increase incidence of certain types of adverse events when used in combination with antiretroviral drugs. Use of herbal drugs in combination with antiretroviral therapy does not significantly improve quality of life index in comparison to antiretroviral drug use only.
journal_name
J Infect Dev Ctriesjournal_title
Journal of infection in developing countriesauthors
Bepe N,Madanhi N,Mudzviti T,Gavi S,Maponga CC,Morse GDdoi
10.3855/jidc.1415subject
Has Abstractpub_date
2011-02-01 00:00:00pages
48-53issue
1eissn
2036-6590issn
1972-2680journal_volume
5pub_type
杂志文章abstract:INTRODUCTION:Dentistry is predominantly a field of surgery, involving exposure to blood and other potentially infectious materials and therefore requires a high standard of infection control and safety practice in controlling cross-contamination and occupational exposures to blood- and saliva-borne diseases. METHODOLO...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.1652
更新日期:2011-11-15 00:00:00
abstract:INTRODUCTION:There is limited knowledge about the associations of Helicobacter pylori (H. pylori) infections in developing countries. This study aimed to determine the current prevalence and associations of H. pylori infection with breastfeeding practices, nutritional status, and recurrent abdominal pain (RAP) in a gro...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.3196
更新日期:2014-04-15 00:00:00
abstract:INTRODUCTION:The pathogenic bacterium Salmonella enterica serovar Typhimurium elicits a variety of genetic programs to adapt to stress conditions encountered within hostile environments such as host phagocytes and preserved food. METHODOLOGY:In this work, differential display (DD) methodology was used to investigate t...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.7033
更新日期:2016-01-31 00:00:00
abstract:INTRODUCTION:Miscarriage is one of the most common adverse pregnancy outcomes. The aim of this study was to investigate the relationship between miscarriage in humans and infections caused by zoonotic bacteria and genital pathogens. METHODOLOGY:Cervicovaginal swabs and placenta samples from 132 women with miscarriage ...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.9829
更新日期:2019-05-31 00:00:00
abstract:INTRODUCTION:Giardiasis is a human health concern worldwide, especially among schoolchildren. Giardia duodenalis genotypes A and B are infective to humans, but their zoonotic potential remains controversial. In Mexico, the most prevalent genotype is A, but B was also detected in southeastern Mexico. In Sinaloa state, n...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.8223
更新日期:2017-02-28 00:00:00
abstract:BACKGROUND:Burkholderia cepacia has the potential to cause fatal infections in ICUs, and multidrug resistance makes them a serious threat in hospital settings. The aim of this study was to evaluate the epidemiology of B. cepacia infections in our hospital. METHODOLOGY:The incidence, clinical characteristics, antimicro...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.124
更新日期:2009-05-01 00:00:00
abstract:INTRODUCTION:Intestinal parasitic infection has been a significant problem in HIV patients, worldwide. In this study, we aimed to measure the prevalence and identify the factors associated with intestinal parasitic infection in people infected with HIV and attending National Public Health Laboratory in Kathmandu, Nepal...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.2785
更新日期:2013-07-15 00:00:00
abstract:BACKGROUND:Salmonella enterica serovars Typhi and Paratyphi A are human host-restricted pathogens. Therefore, there is no small susceptible animal host that can be used to assess the virulence and safety of vaccine strains derived from these Salmonella serovars. However, infant mice have been used to evaluate virulenc...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.1218
更新日期:2010-11-24 00:00:00
abstract:INTRODUCTION:Sources of pathogenic Rickettsia in wildlife are largely unknown in Brazil. In this work, potential tick vectors and seroreactivity of small mammals against four spotted-fever group Rickettsia (R. rickettsii, R. parkeri, R. amblyommii and R. rhipicephali) and Rickettsia bellii from peri-urban areas of Uber...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.7084
更新日期:2016-03-31 00:00:00
abstract:INTRODUCTION:Avian influenza viruses of the H9N2 subtype have been reported to cause human infections. This study demonstrates the impact of nasal viral passaging of avian H9N2 in hamsters on its cross species-pathogenic adaptability and variability of amino acid sequences of the hemagglutinin (HA) and neuraminidase (N...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.4023
更新日期:2014-05-14 00:00:00
abstract::Coronavirus disease 2019 (COVID-19) represents a severe global public health threat. Caused by SARS-Cov-2, COVID-19 is characterized by high transmission rate that correlates with high viral load. The full clinical spectrum of the illness, the prevalence rates of mild symptomatic and asymptomatic cases, and the case f...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章,评审
doi:10.3855/jidc.12805
更新日期:2020-09-30 00:00:00
abstract:INTRODUCTION:Detection of heterogeneous vancomycin-intermediate Staphylococcus aureus (hVISA) is currently problematic. Although the population analysis profile with area under the curve (PAP-AUC) is the gold standard for detecting hVISA strains, this method is time consuming. This study aimed to induce vancomycin non-...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.5059
更新日期:2015-02-19 00:00:00
abstract:INTRODUCTION:Taenia solium cysticercosis is considered an emerging parasitic zoonosis of global importance due to its impact on both agriculture and public health in developing countries. Epidemiological information on human cysticercosis is limited in Nigeria. This study was conducted to determine the seroprevalence o...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.5415
更新日期:2015-08-29 00:00:00
abstract::The case of a Hickman catheter-related bacteremia caused by Gordonia sputi in a patient with breast cancer is presented. Blood cultures grew a Gram-positive rod, susceptible to several antimicrobials, subsequently identified by 16S rRNA gene sequencing as Gordonia sputi. The infection resolved after successful treatme...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.1770
更新日期:2012-02-13 00:00:00
abstract:INTRODUCTION:Due to intercontinental traffic, population migration trends, natural disasters, and climate change, imported malaria remains important to consider in a febrile returning traveler. This study aims to raise awareness about malaria and help European clinicians maintain a working knowledge of this disease by ...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.6799
更新日期:2016-08-02 00:00:00
abstract:INTRODUCTION:Leptospirosis is a zoonotic disease caused by the spirochete of genus Leptospira with widespread distribution in tropical, subtropical and temperate zones. Leptospirosis is often confused with other febrile illnesses including jaundice, dengue, and malaria. Generally, the disease is often underdiagnosed or...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.9545
更新日期:2018-01-31 00:00:00
abstract:INTRODUCTION:Salmonella enterica is recognised worldwide as one of the major agents of human gastrointestinal infections. The aim of the present work is to ascertain the antimicrobial susceptibilities of 150 Salmonella enterica serovar Enteritidis isolates from humans in Morocco during the period from 2000 to 2008. ME...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.806
更新日期:2010-12-23 00:00:00
abstract:INTRODUCTION:The spread of carbapenem-resistant Acinetobacter baumannii (CRAB) is difficult to control especially in the hospitals due to the successful mobilization and evolution of the genetic elements harboring the resistant determinants. The study was conducted to examine the distribution of aminoglycosides, tetrac...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.11410
更新日期:2019-10-31 00:00:00
abstract:UNLABELLED:We describe the first two cases of invasive disease caused by Haemophilus influenzae serotype A in Saudi Arabia. This is the first known reported invasive Haemophilus influenzae serotype A from Saudi Arabia. CASE PRESENTATION:A ten-month-old and three-month-old male not known to have any past history of any...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.6687
更新日期:2016-05-31 00:00:00
abstract:BACKGROUND:Research on the effects of corticosteroids in bacterial meningitis (BM) yielded conflicting results. While some studies reveal that corticosteroids improve the outcomes in BM treatments, others provide strong evidence that patients do not profit from this treatment. We investigated the factors that may impac...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.51
更新日期:2009-12-14 00:00:00
abstract:INTRODUCTION:Men who have sex with men (MSM) are one of the key populations driving HIV/AIDS epidemic globally. To date, MSM is the only population in Ukraine where the prevalence and incidence of HIV is increasing. As HIV-positive MSM might feel uncomfortable to report homosexual intercourses as a possible mode of tra...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.11967
更新日期:2020-11-16 00:00:00
abstract:INTRODUCTION:Helicobacter pylori cause damage to gastric epithelial cells and alterations in the p53 gene that lead to cancer development. This study aimed to determine the correlation of p53 expression with H. pylori using immunohistochemistry, RFLP-PCR, and histopathology. METHODOLOGY:Gastric biopsy samples from gas...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.2993
更新日期:2013-09-16 00:00:00
abstract:INTRODUCTION:Hand, foot, and mouth disease (HFMD) is a common childhood illness caused by enteroviruses. A passive surveillance system has been implemented in Shanghai Pudong since 2008 and etiology surveillance since 2009.We characterized the epidemiology and the etiology of HFMD in Pudong from 2008-2013. METHODOLOGY...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.6118
更新日期:2016-06-30 00:00:00
abstract:INTRODUCTION:The current cohort study was conducted to determine the frequency and compare the mortality rate with associated characteristics among low birth weight and normal birth weight infants during the neonatal period at a tertiary healthcare facility, Karachi. METHODOLOGY:Close-ended structured questionnaires w...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.3569
更新日期:2014-09-13 00:00:00
abstract:BACKGROUND:Expansion of the health care workforce in Peru to combat tuberculosis (TB) includes both professional health care providers (HCPs) such as doctors and nurses, and non-professional HCPs such as community health workers (CHWs). We describe the knowledge and attitudes of these HCPs, and identify modifiable barr...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.335
更新日期:2009-12-15 00:00:00
abstract:INTRODUCTION:The correlation of Chlamydia pneumoniae to coronary artery disease (CAD) in Jordan was investigated in this study. METHODOLOGY:Totals of 361 atherosclerotic patients and 392 apparently healthy controls of both sexes were enrolled. C. pneumoniae-specific IgG antibodies were measured by the microimmunofluor...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.7363
更新日期:2016-05-31 00:00:00
abstract::Leukocyte adhesion deficiency type 1 (LAD-1) is a rare, inherited immunodeficiency that affects one per million people yearly and usually presents with recurrent, indolent bacterial infections of the skin, mouth, and respiratory tract and impaired pus formation and wound healing. A 13-year-old girl diagnosed LAD-I at ...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.387
更新日期:2010-03-29 00:00:00
abstract:INTRODUCTION:Antimicrobial resistance (AR) is a multifaceted problem of global significance. In addition to developing new drugs and using antimicrobial guidelines, it is essential that health professionals understand all aspects of the problem and the most effective ways to handle it. This study evaluated pharmacists'...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.4853
更新日期:2015-03-15 00:00:00
abstract:INTRODUCTION:El Salvador is regarded as a highly endemic country for Chagas disease, as evidenced by the relatively high estimated positive serology rate for Trypanosoma cruzi among blood donors. This study aimed to identify the factors contributing to this high rate by analyzing changes in T. cruzi seroprevalence. ME...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.4035
更新日期:2014-08-13 00:00:00
abstract:BACKGROUND:This work demonstrates successful propagation of HCV in HepG2 and human blood cells as well as viral shedding into their culture media. The influence of Schistosoma mansoni crude soluble egg antigens (SEA) on the rate of viral propagation in both mammalian cells was also monitored. METHODOLOGY:HepG2 cells w...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.522
更新日期:2010-05-01 00:00:00