Abstract:
BACKGROUND:Burkholderia cepacia has the potential to cause fatal infections in ICUs, and multidrug resistance makes them a serious threat in hospital settings. The aim of this study was to evaluate the epidemiology of B. cepacia infections in our hospital. METHODOLOGY:The incidence, clinical characteristics, antimicrobial susceptibility, and outcomes of nosocomial B. cepacia infections during a five-year period were retrospectively analysed according to the infection control committee records. RESULTS:A total of 39 cases with nosocomial B. cepacia infection were included in the study. B. cepacia was identified from 0.7% of the nosocomial isolates. Its incidence was 0.26 per 1,000 admissions with 53.8% crude mortality rate. The most frequent nosocomial B. cepacia infection was pneumonia (58.9%), followed by bloodstream infections (25.6%), surgical site infections (7.6%), urinary tract infections, (5.1%), and skin-soft tissue infections (2.5%). Nosocomial B. cepacia infections were most commonly observed in intensive care units (61.5%). The most active antimicrobial agents were piperacillin-tazobactam, cefoperazone-sulbactam, and carbapenems. CONCLUSIONS:The incidence of nosocomial B. cepacia infections was rare in our hospital, and no outbreak was detected during the study period. However, infections caused by B. cepacia should be taken into consideration because of their high mortality due to multidrug resistance in ICU settings.
journal_name
J Infect Dev Ctriesjournal_title
Journal of infection in developing countriesauthors
Dizbay M,Tunccan OG,Sezer BE,Aktas F,Arman Ddoi
10.3855/jidc.124subject
Has Abstractpub_date
2009-05-01 00:00:00pages
273-7issue
4eissn
2036-6590issn
1972-2680journal_volume
3pub_type
杂志文章abstract:INTRODUCTION:The novel coronavirus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is responsible for the coronavirus disease 2019 (COVID-19). First COVID-19 case was detected in March, 10, 2020 in Turkey and as of May, 18, 2020 148,067 cases have been identified and 4096 citizens have died. Tuberculosis (...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.13152
更新日期:2020-07-31 00:00:00
abstract:INTRODUCTION:Evaluating the attenuation of influenza viruses in animal studies is important in developing safe and effective vaccines. This study aimed to demonstrate that the microRNA (miRNA)-let-7b-mediated attenuated influenza viruses (miRT-H1N1) are sufficiently attenuated and safe in mice. METHODOLOGY:The pathoge...
journal_title:Journal of infection in developing countries
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abstract:INTRODUCTION:Norovirus is not usually investigated in diarrheal patients in Bangladesh which may account for the many cases where no pathogens are identified. METHODOLOGY:Stool specimens collected from diarrheal patients from three hospitals in Bangladesh during 2011 were investigated for norovirus RNA using real-time...
journal_title:Journal of infection in developing countries
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更新日期:2013-11-15 00:00:00
abstract:INTRODUCTION:Hypodermosis is an ectoparasitic disease of cattle caused by Hypoderma lineatum and Hypoderma bovis. It is an important health problem of cattle, leading to considerable economic losses. There are various factors that are involved in the spread of this disease such as herd size, location, temperature, humi...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.5387
更新日期:2015-08-29 00:00:00
abstract::The case of a Hickman catheter-related bacteremia caused by Gordonia sputi in a patient with breast cancer is presented. Blood cultures grew a Gram-positive rod, susceptible to several antimicrobials, subsequently identified by 16S rRNA gene sequencing as Gordonia sputi. The infection resolved after successful treatme...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.1770
更新日期:2012-02-13 00:00:00
abstract:INTRODUCTION:This research aimed to determine the association of the combination of H. pylori infection and TP53 codon 72 polymorphism with non-cardia gastric cancer (GC) in Vietnam. METHODOLOGY:A total of 164 patients with non-cardia GC and 164 patients with peptic ulcer disease or functional dyspepsia in controls ma...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.11488
更新日期:2019-11-30 00:00:00
abstract:INTRODUCTION:Avian influenza viruses of the H9N2 subtype have been reported to cause human infections. This study demonstrates the impact of nasal viral passaging of avian H9N2 in hamsters on its cross species-pathogenic adaptability and variability of amino acid sequences of the hemagglutinin (HA) and neuraminidase (N...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.4023
更新日期:2014-05-14 00:00:00
abstract:INTRODUCTION:Vaccine strategies represent an essential component for the future control of schistosomiasis. This work aimed to evaluate the role of detergents for potentiating the effect of Schistosoma mansoni tegumental antigens (TA) against challenge infection. METHODOLOGY:Two detergents; Triton X-100 (TX-100) and s...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.1199
更新日期:2011-03-21 00:00:00
abstract:INTRODUCTION:Dengue virus (DENV) is principally transmitted by the Aedes aegypti mosquito. To date, mosquito population control remains the key strategy for reducing the continuing spread of DENV. The focus on the development of new vector control strategies through an understanding of the mosquito-virus relationship i...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.6422
更新日期:2015-12-30 00:00:00
abstract:INTRODUCTION:Sepsis is a major cause of childhood death worldwide. In developing countries, epidemiological data about sepsis is scarce. This study describes and compares the frequency of etiological agents and initial sites of infection in children with or without sepsis, identifying risk factors and assessing outcome...
journal_title:Journal of infection in developing countries
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更新日期:2017-09-05 00:00:00
abstract:INTRODUCTION:There is limited knowledge about the associations of Helicobacter pylori (H. pylori) infections in developing countries. This study aimed to determine the current prevalence and associations of H. pylori infection with breastfeeding practices, nutritional status, and recurrent abdominal pain (RAP) in a gro...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.3196
更新日期:2014-04-15 00:00:00
abstract:INTRODUCTION:The present study was conducted to evaluate the prevalence of Trichuris spp. and other intestinal parasitic infections in owned cats on St. Kitts. METHODOLOGY:The feces of 41 non-feral cats (23 indoor only; 18 indoor/outdoor) were examined for the presence of Trichuris spp. eggs. RESULTS:Nine (22%) of th...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.5778
更新日期:2015-01-15 00:00:00
abstract:BACKGROUND:Streptococcus pneumoniae is a major human pathogen. The emergence of penicillin resistant strains since the 1970s has been life threatening and the evolution of the bacteria have enabled itself to develop resistance to many other antibiotics such as the macrolides and the fluoroquinolones. This study aims to...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.262
更新日期:2008-06-01 00:00:00
abstract:INTRODUCTION:Bacille Calmette-Guerin (BCG) vaccination remains a routine immunization in primary care in tuberculosis (TB)-endemic areas, though several studies found that its efficacy was inconclusive. Natural resistance-asociated machrophage protein 1 (NRAMP1) polymorphism has been shown to result in higher susceptib...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.5047
更新日期:2015-01-15 00:00:00
abstract:INTRODUCTION:Intestinal and extraintestinal infections by Aeromonas spp., remain controversial, due to the existence of healthy carriers of Aeromonas spp. In children under five years old, the diarrhea of infectious origin constitutes the second cause of mortality and remains a major concern for public health. The aim ...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.12966
更新日期:2020-10-31 00:00:00
abstract:INTRODUCTION:Salmonella is well recognized as an aetiological agent of gastrointestinal and diarrhoeal disease. Salmonella enterica serotype Enteritidis (Salmonella Enteritidis) is one of the commonest serotypes associated with foodborne illness. In South Africa, we compared Salmonella Enteritidis strains isolated from...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.5393
更新日期:2014-12-15 00:00:00
abstract:INTRODUCTION:When a surgical operation is to be conducted through a hair bearing part of the body, hair removal is often performed. This study aimed to evaluate the relationship of two methods of preoperative hair removal to postoperative wound infection in a developing country where razor shaving is very popular. MET...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章,随机对照试验
doi:10.3855/jidc.1527
更新日期:2011-10-13 00:00:00
abstract:INTRODUCTION:Gallbladder stones are a very frequently occurring condition. Despite bile bactericidal activity, many bacteria have been detected inside the gallbladder, and gallstones facilitate their presence. Between 3% and 5% of the patients with Salmonella spp. infection develop the carrier stage, with the bacteria ...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.8258
更新日期:2017-03-31 00:00:00
abstract::Leishmaniasis is a clinically heterogeneous syndrome caused by intracellular protozoan parasites of the genus Leishmania. The clinical spectrum of leishmaniasis encompasses subclinical (not apparent), localized (skin lesion), and disseminated (cutaneous, mucocutaneous, and visceral) infection. This spectrum of manifes...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章,评审
doi:10.3855/jidc.4310
更新日期:2014-08-13 00:00:00
abstract::Lebanon yearly witnesses a high flux of expatriates and workers from Dengue virus (DENV) endemic regions. Multiple cases of Dengue fever have been documented at the American University of Beirut Medical Center (AUBMC) in travellers to endemic regions. Given the presence of the Aedes aegypti mosquito in Lebanon, introd...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.9954
更新日期:2018-04-30 00:00:00
abstract:INTRODUCTION:Detection of heterogeneous vancomycin-intermediate Staphylococcus aureus (hVISA) is currently problematic. Although the population analysis profile with area under the curve (PAP-AUC) is the gold standard for detecting hVISA strains, this method is time consuming. This study aimed to induce vancomycin non-...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.5059
更新日期:2015-02-19 00:00:00
abstract:BACKGROUND:Brucella is a facultative, intracellular pathogen that causes severe disease in animals and humans. Immunity against Brucella involves both humoral and cellular responses. To investigate the characteristics of immune response in acute brucellosis in Sprague-Dawley (SD) rats, IgG and its subclass specific imm...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.248
更新日期:2009-06-01 00:00:00
abstract:INTRODUCTION:Shigellosis is a major public health concern worldwide. This study intended to assess the baseline genotyping data among local Shigella sonnei strains spanning over five years. METHODOLOGY:Fifty non-repeat clinical strains of S. sonnei isolated from stools of patients in different hospitals in Nanjing, Ch...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.4933
更新日期:2014-12-15 00:00:00
abstract:INTRODUCTION:Infection from Hepatitis B primarily results from peri-partum vertical transmission and the risk increases in the presence of hepatitis B e antigen. We aimed to evaluate a new screening program for hepatitis B in pregnant women as a component of antenatal services in a marginalized population. METHODOLOGY...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.7422
更新日期:2016-04-28 00:00:00
abstract:INTRODUCTION:Hepatitis E is considered an emerging human viral disease with many evidences of zoonotic nature of disease, and swine are the main reservoir of HEV. The aim of this study was to determine HEV seroprevalence in commercial pig farms, backyard pigs, slaughtered pigs and wild boars in the region of the city B...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.12552
更新日期:2020-06-30 00:00:00
abstract:BACKGROUND:The treatment of methicillin-resistant staphylococcal infections has been a growing problem both in and out of hospitals for the past 30 years. Therefore, there is a need for other antibiotics as an alternative to glycopeptides in the treatment of methicillin-resistant staphylococcal infections. This study i...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.3867
更新日期:2013-11-15 00:00:00
abstract::Zika virus (ZIKV) infection is spreading rapidly within the Americas after originating from an outbreak in Brazil. We describe the current ZIKV infection epidemic in Brazil and the neurological symptoms arising. First cases of an acute exanthematic disease were reported in Brazil's Northeast region at the end of 2014....
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.8217
更新日期:2016-02-28 00:00:00
abstract:INTRODUCTION:Rotavirus (RV) is the leading cause of severe diarrhea-associated morbidity and mortality among children worldwide. Limited data exist on the epidemiology and burden of rotavirus gastroenteritis in Armenia. The purpose of this study is to estimate the economic losses and describe the epidemiological charac...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.10883
更新日期:2019-04-30 00:00:00
abstract:INTRODUCTION:Screening blood donors for blood-borne pathogens is very critical for the recipient's safety. Similar to hepatitis B and C infections, hepatitis G infection is transmitted through contaminated blood and causes acute and chronic hepatitis. Previous reports have shown that the prevalence of hepatitis G virus...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.3796
更新日期:2014-01-15 00:00:00
abstract::The increasing prevalence of foodborne diseases observed in developing countries has been linked to a rise in the consumption of raw foods. However, unlike the classical pathogens that are commonly implicated in foodborne illnesses, members of the genus Acinetobacter are rarely associated with diarrheal disease, proba...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章,评审
doi:10.3855/jidc.8418
更新日期:2017-02-28 00:00:00