Abstract:
INTRODUCTION:Screening blood donors for blood-borne pathogens is very critical for the recipient's safety. Similar to hepatitis B and C infections, hepatitis G infection is transmitted through contaminated blood and causes acute and chronic hepatitis. Previous reports have shown that the prevalence of hepatitis G virus (HGV) RNA among healthy Saudi donors was 1%-2%. However, the exposure rate of this virus has never been studied. We hypothesized that the prevalence of HGV infection may have changed overtime due to socio-economic and environmental factors. Since hepatitis B and C infections are endemic in Saudi Arabia, we investigated the exposure rate of HGV infection in healthy donors and chronically infected hepatitis B and C patients. METHODOLOGY:A prospective study was done on healthy donors and patients with chronic HBV and HCV infections. Hepatitis B and C viral loads were measured by real-time polymerase chain reaction. HGV exposure rate was evaluated by detection of HGV antibodies. RESULTS:Analysis of samples from healthy donors (n = 210), chronic HBV+ patients (n = 169), and chronic HCV+ patients (n = 105) showed that nine samples (4.3%), seven samples (4.1%), and four samples (3.8%) were positive for HGV antibodies, respectively. The non-significant difference in the exposure rates of HGV between the study groups may indicate that HGV infection occurs independent of HBV or HCV infections. CONCLUSIONS:We showed for the first time that the exposure rate of HGV infection among the Saudi population is 4.3%, and we recommend HGV screening for all blood donors.
journal_name
J Infect Dev Ctriesjournal_title
Journal of infection in developing countriesauthors
Alhetheel A,El-Hazmi MMdoi
10.3855/jidc.3796subject
Has Abstractpub_date
2014-01-15 00:00:00pages
110-5issue
1eissn
2036-6590issn
1972-2680journal_volume
8pub_type
杂志文章abstract:UNLABELLED:We describe the first two cases of invasive disease caused by Haemophilus influenzae serotype A in Saudi Arabia. This is the first known reported invasive Haemophilus influenzae serotype A from Saudi Arabia. CASE PRESENTATION:A ten-month-old and three-month-old male not known to have any past history of any...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.6687
更新日期:2016-05-31 00:00:00
abstract:INTRODUCTION:The widespread use of tigecycline raises the question of increasing infection rates of Pseudomonas aeruginosa (PA) in ICUs which are not affected by this antibiotic. OBJECTIVE:The aim of this study was to determine if treatment with tigecycline is a risk factor for PA infection in ICU patients. METHODOLO...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.4700
更新日期:2015-03-15 00:00:00
abstract:INTRODUCTION:Avian influenza viruses of the H9N2 subtype have been reported to cause human infections. This study demonstrates the impact of nasal viral passaging of avian H9N2 in hamsters on its cross species-pathogenic adaptability and variability of amino acid sequences of the hemagglutinin (HA) and neuraminidase (N...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.4023
更新日期:2014-05-14 00:00:00
abstract:BACKGROUND:Tungiasis, caused by the sand flea Tunga penetrans, is highly prevalent in many resource-poor communities in sub-Saharan Africa, Latin America and the Caribbean. Studies on knowledge and treatment practices related to tungiasis in affected populations are virtually nonexistent. To fill this gap, we performed...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.418
更新日期:2009-07-01 00:00:00
abstract:BACKGROUND:In the year 2005, an epidemic of Japanese encephalitis (JE) occurred in the northern states of India. The present study was planned to reconfirm the circulation of JE in the area and to assess the trend of the disease to slow down the burden of JE. METHODOLOGY:Surveillance was conducted to identify patients...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.470
更新日期:2009-08-30 00:00:00
abstract:INTRODUCTION:Staphylococcal colonization is a risk factor for healthcare-associated infections, which are frequent in Neonatal Intensive Care Units (NICU). This study analyzed microbiology, epidemiology and clinical aspects of Staphylococcus spp. colonizing neonates. METHODOLOGY:Nasal or periumbilical swabs were evalu...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.11241
更新日期:2019-09-30 00:00:00
abstract:INTRODUCTION:Despite tremendous progress made toward elimination, measles continues to pose a great threat to the health of children in developing countries. The objective of this study was to summarize and analyze the clinical characteristics and treatment experience of serious complications of measles pneumonia in ch...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.6534
更新日期:2015-10-29 00:00:00
abstract:BACKGROUND:Brucella is a facultative, intracellular pathogen that causes severe disease in animals and humans. Immunity against Brucella involves both humoral and cellular responses. To investigate the characteristics of immune response in acute brucellosis in Sprague-Dawley (SD) rats, IgG and its subclass specific imm...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.248
更新日期:2009-06-01 00:00:00
abstract:INTRODUCTION:Plasmid-mediated quinolone resistance, which complicates treatment, has been increasingly identified in Escherichia coli isolates worldwide. The purpose of this study was to identify the plasmid-mediated qnrA and qnrB genes among the quinolone-resistant Escherichia coli isolated from urinary tract infectio...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.3746
更新日期:2014-07-14 00:00:00
abstract:INTRODUCTION:Norovirus is not usually investigated in diarrheal patients in Bangladesh which may account for the many cases where no pathogens are identified. METHODOLOGY:Stool specimens collected from diarrheal patients from three hospitals in Bangladesh during 2011 were investigated for norovirus RNA using real-time...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.2944
更新日期:2013-11-15 00:00:00
abstract:INTRODUCTION:There is an urgent need for affordable point-of-care diagnostics for the differentiation of febrile illnesses and the confirmation of typhoid in endemic countries. METHODOLOGY:Blood samples were collected from febrile patients with clinical suspicion of typhoid and screened for typhoid fever using the Wid...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.1836
更新日期:2011-07-27 00:00:00
abstract:INTRODUCTION:Previous sentinel surveys of HIV in Nigeria studied pregnant women attending antenatal care, thereby omitting other important high-risk groups. We therefore investigated the prevalence of HIV/AIDS in low- and high-risk populations in the state of Plateau, Nigeria. METHODOLOGY:Blood samples were collected ...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.1872
更新日期:2012-12-15 00:00:00
abstract::Splenic abscess due to Brucella spp. is extremely rare. We report a case of a splenic abscess due to Brucella spp. in a 61-year-old male patient. Brucella slide and tube agglutination tests (Wright) were positive while blood culture and culture from splenic tissue yielded negative results. The abdominal ultrasonograph...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.204
更新日期:2008-10-01 00:00:00
abstract:BACKGROUND:Salmonella enterica serovars Typhi and Paratyphi A are human host-restricted pathogens. Therefore, there is no small susceptible animal host that can be used to assess the virulence and safety of vaccine strains derived from these Salmonella serovars. However, infant mice have been used to evaluate virulenc...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.1218
更新日期:2010-11-24 00:00:00
abstract:INTRODUCTION:Helicobacter pylori is a principal cause of gastric cancer. The aim of this study was to determine the prevalence and contribution of duodenal ulcer promoting gene A (dupA), the plasticity region genes and sigma factors in relation to their pathological expression of H. pylori infections in the Nigerian po...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.11746
更新日期:2020-02-29 00:00:00
abstract:INTRODUCTION:Women infected with human immunodeficiency virus (HIV) have a higher risk of contracting human papillomavirus (HPV) infections and are more prone to develop cervical cancer. The objective of this study was to determine the prevalence of HPV and its association with risk factors among Moroccan women living ...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.9711
更新日期:2018-06-30 00:00:00
abstract:INTRODUCTION:This study aims at defining through a retrospective evaluation, the clinical parameters affecting the clinical course and consequently the management of patients presenting with cervicofacial abscesses. METHODOLOGY:A total of 394 patients diagnosed with abscess at the University of Sassari Otorhinolaryngo...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.12191
更新日期:2020-05-31 00:00:00
abstract:INTRODUCTION:In Georgia as in most Eastern European countries, injecting drug use remains one of the leading transmission modes of HIV infection. This paper aims to identify HIV prevalence and risk determinants among people who inject drugs (PWID). METHODOLOGY:A cross -sectional, anonymous bio-behavioral survey of PWI...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.9103
更新日期:2017-10-31 00:00:00
abstract:INTRODUCTION:Bacille Calmette-Guerin (BCG) vaccination remains a routine immunization in primary care in tuberculosis (TB)-endemic areas, though several studies found that its efficacy was inconclusive. Natural resistance-asociated machrophage protein 1 (NRAMP1) polymorphism has been shown to result in higher susceptib...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.5047
更新日期:2015-01-15 00:00:00
abstract:INTRODUCTION:Although omphalitis (umbilical infections) among newborns is common and a major cause of neonatal deaths in developing countries, information on its burden and etiology from community settings is lacking. This study aimed to determine the incidence and etiology of omphalitis in newborns in high neonatal mo...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章,评审
doi:10.3855/jidc.1229
更新日期:2011-12-13 00:00:00
abstract:BACKGROUND:Non-typhoidal Salmonella are frequently food-borne zoonotic pathogens that may cause invasive disease in HIV-positive individuals. METHODOLOGY:Invasive isolates (n = 652) of Salmonella Typhimurium from human patients in Gauteng Province of South Africa were investigated for the years 2006 and 2007. Bacteria...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.549
更新日期:2009-09-15 00:00:00
abstract:INTRODUCTION:Klebsiella pneumoniae is an opportunistic pathogen that causes a range of diseases. The appearance of extended-spectrum β-lactamase -and carbapenemase-producing strains, in addition to the biofilm-forming phenotype, is a major problem in the clinical environment. METHODOLOGY:A total of 33 clinical K. pneu...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.9677
更新日期:2018-03-31 00:00:00
abstract:INTRODUCTION:The pathogenic bacterium Salmonella enterica serovar Typhimurium elicits a variety of genetic programs to adapt to stress conditions encountered within hostile environments such as host phagocytes and preserved food. METHODOLOGY:In this work, differential display (DD) methodology was used to investigate t...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.7033
更新日期:2016-01-31 00:00:00
abstract:INTRODUCTION:Typhoid fever is a common disease in Yunnan province; however, the resistant phenotype and epidemic characteristics of Salmonella in this area are still unclear. In this study, a 15-year surveillance of antimicrobial susceptibility of Salmonella is reported. METHODOLOGY:From January 1999 to December 2013,...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.5420
更新日期:2015-04-15 00:00:00
abstract:INTRODUCTION:Salmonella enterica subspecies enterica serovar Choleraesuis is a host-adapted, facultative, intracellular pathogen that causes swine paratyphoid. Its antimicrobial resistance presents a challenge to feed manufacturing industries. However, stopping antibiotics in animal feed would have economic implication...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.3861
更新日期:2014-11-13 00:00:00
abstract:BACKGROUND:The diagnosis of extra-pulmonary tuberculosis (EPTB) by conventional methods such as culture and microscopy has low sensitivity and requires an invasive procedure. A simple rapid serological test would be of great value. METHODS:Six antigens (ESAT-6, Ag85A, TB10.4, Rv3881c, lipoarabinomannan (LAM) and Ara6-...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.116
更新日期:2010-03-08 00:00:00
abstract::The incidence of invasive salmonellosis has increased among children and HIV-infected adults in Malawi. This has been associated with the emergence of drug resistance in the non-typhoidal Salmonella serovars Enteritidis and Typhimurium. In contrast, S. Typhi isolates have remained fully sensitive to commonly used anti...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章,评审
doi:10.3855/jidc.158
更新日期:2008-12-01 00:00:00
abstract:INTRODUCTION:Salmonella enterica serotype Kentucky was isolated from septic poultry in Nigeria. The objective of this study was to characterize this isolate by screening for SGI1 and hyper-virulence. METHODOLOGY:The strain was characterized by identification of Salmonella genomic island 1 (SGI1) through a PCR assay an...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.1988
更新日期:2012-06-15 00:00:00
abstract:INTRODUCTION:Malaria remains an important public health problem despite recent scientific breakthroughs regarding knowledge about malaria and treatment strategies. The objective of this study was to analyze malaria patients' knowledge about the disease, its treatment and prevention, linking it to drug treatment adheren...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.7129
更新日期:2016-11-24 00:00:00
abstract::Tuberculosis (TB) remains a serious public health problem, worsened by an increased frequency of multidrug-resistant (MDR) Mycobacterium tuberculosis strains. The World Health Organization (WHO) and the International Union Against Tuberculosis and Lung Disease (IUATLD) launched the Global Project on Anti-Tuberculosis ...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章,评审
doi:10.3855/jidc.31
更新日期:2009-04-30 00:00:00