Extended phylogenetic analysis of a new Israeli isolate of Brevicoryne brassicae virus (BrBV-IL) suggests taxonomic revision of the genus Iflavirus.

abstract：:Much of the worlds' population is in active or imminent danger from established infectious pathogens, while sporadic and pandemic infections by these and emerging agents threaten everyone. RNA polymerases (RNApol) generate enormous genetic and consequent antigenic heterogeneity permitting both viruses and cellular pat...

journal_title：Virology journal

authors： Sallie R

更新日期：2005-08-22 00:00:00

abstract：:Ten potential reference genes were compared for their use in experiments investigating cellular mRNA expression of virus infected cells. Human cell lines were infected with Cytomegalovirus, Human Herpesvirus-6, Camelpox virus, SARS coronavirus or Yellow fever virus. The expression levels of these genes and the viral r...

journal_title：Virology journal

authors： Radonić A,Thulke S,Bae HG,Müller MA,Siegert W,Nitsche A

更新日期：2005-02-10 00:00:00

abstract：BACKGROUND:Human adenoviruses (Ads) have substantial potential for clinical applications in cancer patients. Conditionally replicating adenoviruses (CRAds) include oncolytic adenoviruses in which expression of the immediate early viral transactivator protein E1A is controlled by a cancer cell-selective promoter. To enh...

journal_title：Virology journal

authors： Fontecedro AC,Lutschg V,Eichhoff O,Dummer R,Greber UF,Hemmi S

更新日期：2010-07-29 00:00:00

abstract：BACKGROUND:Papillomaviruses (PVs) establish a persistent infection in the proliferating basal cells of the epithelium. The viral genome is replicated and maintained as a low-copy nuclear plasmid in basal keratinocytes. Bovine and human papillomaviruses (BPV and HPV) are known to utilize two viral proteins; E1, a DNA he...

journal_title：Virology journal

authors： Pittayakhajonwut D,Angeletti PC

更新日期：2010-06-10 00:00:00

abstract：:In September 2012, a novel coronavirus was isolated from a patient in Saudi Arabia who had died of an acute respiratory illness and renal failure. The clinical presentation was reminiscent of the outbreak caused by the SARS-coronavirus (SARS-CoV) exactly ten years ago that resulted in over 8000 cases. Sequence analysi...

journal_title：Virology journal

authors： Khan G

更新日期：2013-02-28 00:00:00

abstract：:We undertook one of the most detailed studies on the distribution of alpha2,3 sialic acid (SA)-galactose (gal) (avian type) and alpha2,6SA-gal (human type) receptors on different tissues of chickens, ducks and turkeys of varying age groups. On the tracheal epithelium, all 3 bird species expressed strong positive stain...

journal_title：Virology journal

authors： Pillai SP,Lee CW

更新日期：2010-01-12 00:00:00

abstract：BACKGROUND:Papillomaviruses (PVs) infecting artiodactyls are very diverse, and only second in number to PVs infecting primates. PVs associated to lesions in economically important ruminant species have been isolated from cattle and sheep. METHODS:Potential PV DNA from teat lesions of a Damascus goat was isolated, clon...

journal_title：Virology journal

authors： Willemsen A,van den Boom A,Dietz J,Bilge Dagalp S,Dogan F,Bravo IG,Ehrhardt A,Ehrke-Schulz E

更新日期：2020-10-30 00:00:00

abstract：BACKGROUND:Previously, we have reported the isolation and molecular characterization of human Hepatitis C virus genotype 1 (HCV-1) from infected patients. We are now reporting an analysis of HCV obtained from patients infected with HCV genotype 3 (HCV-3) as diagnosed by clinical laboratories. RESULTS:HCV was cultured ...

journal_title：Virology journal

authors： Revie D,Alberti MO,Prichard JG,Kelley AS,Salahuddin SZ

更新日期：2010-07-13 00:00:00

abstract：:Lytic bacteriophage 0305phi8-36 forms visually observed aggregates during plaque formation. Aggregates intrinsically lower propagation potential. In the present study, the following observations indicate that lost propagation potential is regained with time: (1) Aggregates sometimes concentrate at the edge of clear pl...

journal_title：Virology journal

authors： Serwer P,Hayes SJ,Lieman K

更新日期：2007-12-04 00:00:00

abstract：:Six major Hepatitis C virus (HCV) genotypes and hundreds of subtypes have been identified globally. All these genotypes are generally studied for epidemiology, their vaccine development and clinical management. This article comments the frequency distribution of various HCV genotypes circulate in different areas/distr...

journal_title：Virology journal

authors： Ali A,Ahmed H,Idrees M

更新日期：2010-08-26 00:00:00

abstract：BACKGROUND:Highly pathogenic avian influenza virus (AIV) subtype H5N1 remains a threat to poultry. Duck enteritis virus (DEV)-vectored vaccines expressing AIV H5N1 hemagglutinin (HA) may be viable AIV and DEV vaccine candidates. METHODS:To facilitate the generation and further improvement of DEV-vectored HA(H5) vaccin...

journal_title：Virology journal

authors： Wang J,Ge A,Xu M,Wang Z,Qiao Y,Gu Y,Liu C,Liu Y,Hou J

更新日期：2015-08-13 00:00:00

abstract：BACKGROUND:Influenza A virus poses a continuous threat to global public health. Design of novel universal drugs and vaccine requires a careful analysis of different strains of Influenza A viral genome from diverse hosts and subtypes. We performed a systematic in silico analysis of Influenza A viral segments of all avai...

journal_title：Virology journal

authors： ElHefnawi M,Alaidi O,Mohamed N,Kamar M,El-Azab I,Zada S,Siam R

更新日期：2011-01-27 00:00:00

abstract：BACKGROUND:Dengue fever is perhaps the most important viral re-emergent disease especially in tropical and sub-tropical countries, affecting about 50 million people around the world yearly. In Colombia, dengue virus was first detected in 1971 and still remains as a major public health issue. Although four viral serotyp...

journal_title：Virology journal

authors： Méndez JA,Usme-Ciro JA,Domingo C,Rey GJ,Sánchez JA,Tenorio A,Gallego-Gomez JC

更新日期：2012-03-09 00:00:00

abstract：BACKGROUND:Containment of influenza A H1N1 virus spread was implemented successfully in Xiamen, with large-scale inoculation to reduce morbidity. To identify beneficial elements and to guide decision-making in epidemic containment, we analyzed the epidemiologic parameters and evaluated the control measures. METHOD:We ...

journal_title：Virology journal

authors： Shen J,Niu J

更新日期：2012-01-17 00:00:00

abstract：BACKGROUND:The family Mesoniviridae (order Nidovirales) comprises of a group of positive-sense, single-stranded RNA ([+]ssRNA) viruses isolated from mosquitoes. FINDINGS:Thirteen novel insect-specific virus isolates were obtained from mosquitoes collected in Indonesia, Thailand and the USA. By electron microscopy, the...

journal_title：Virology journal

authors： Vasilakis N,Guzman H,Firth C,Forrester NL,Widen SG,Wood TG,Rossi SL,Ghedin E,Popov V,Blasdell KR,Walker PJ,Tesh RB

更新日期：2014-05-20 00:00:00

abstract：:Adenovirus has a wide tissue tropism. The virus attaches to the surface of cells via the fiber protein knob binding to the Coxsackie and Adenovirus receptor known as CAR. Virus entry inside cells is facilitated by integrins αVβ3 and αVβ5. Mice platelets are shown to be the predominant Ad binding blood cell type and th...

journal_title：Virology journal

authors： Gupalo E,Buriachkovskaia L,Othman M

更新日期：2011-09-30 00:00:00

abstract：BACKGROUND:Hepatitis C virus (HCV) is a major cause of chronic hepatitis and hepatocellular carcinoma (HCC) and different HCV genotypes show characteristic variations in their pathological properties. Insulin resistance (IR) occurs early in HCV infection and may synergize with viral hepatitis in HCC development. Egypt ...

journal_title：Virology journal

authors： Mohamed AA,Loutfy SA,Craik JD,Hashem AG,Siam I

更新日期：2011-11-01 00:00:00

abstract：BACKGROUND:Human respiratory syncytial virus (hRSV) and human metapneumovirus (hMPV) are two of the most frequent respiratory pathogens that circulate worldwide. Infection with either virus can lead to hospitalization of young children, immunocompromised people and the elderly.A better understanding of the epidemiologi...

journal_title：Virology journal

authors： Sastre P,Ruiz T,Schildgen O,Schildgen V,Vela C,Rueda P

更新日期：2012-07-02 00:00:00

abstract：BACKGROUND:The genus Orbivirus includes several species that infect livestock - including Bluetongue virus (BTV) and African horse sickness virus (AHSV). These viruses have linear dsRNA genomes divided into ten segments, all of which have previously been assumed to be monocistronic. RESULTS:Bioinformatic evidence is p...

journal_title：Virology journal

authors： Firth AE

更新日期：2008-04-14 00:00:00

abstract：BACKGROUND:It is becoming progressively more understandable that genetic variability of viruses is a major challenge in translating the laboratory findings to clinic. Genetic variability is the underlying cause of variant viral proteins which are not targetable by host immunological machinery. METHODS:500 patients wer...

journal_title：Virology journal

authors： Kanwal S,Mahmood T

更新日期：2014-09-30 00:00:00

abstract：BACKGROUND:HCV is prevalent throughout the world. It is a major cause of chronic liver disease. There is no effective vaccine and the most common therapy, based on Peginterferon, has a success rate of ~50%. The mechanisms underlying viral resistance have not been elucidated but it has been suggested that both host and ...

journal_title：Virology journal

authors： Yamasaki LH,Arcuri HA,Jardim AC,Bittar C,de Carvalho-Mello IM,Rahal P

更新日期：2012-01-12 00:00:00

abstract：BACKGROUND:Hepatitis C virus (HCV) Core protein regulates multiple signaling pathways and alters cellular genes expression responsible for HCV induced pathogenesis leading to hepatocellular carcinoma (HCC). Prevalence of HCV genotype 3a associated HCC is higher in Pakistan as compare to the rest of world; however the m...

journal_title：Virology journal

authors： Jahan S,Khaliq S,Siddiqi MH,Ijaz B,Ahmad W,Ashfaq UA,Hassan S

更新日期：2011-11-23 00:00:00

abstract：BACKGROUND:Multiple studies proved that miRNAs have a causal role in tumorigenesis. Some miRNAs are regulated by epigenetic alterations in their promoter regions and can be activated by chromatin- modifying drugs. METHODS:We treated cervical cancer cells with 5-aza-2'-deoxycytidine and get a microarray analysis. Dysre...

journal_title：Virology journal

authors： Yao T,Rao Q,Liu L,Zheng C,Xie Q,Liang J,Lin Z

更新日期：2013-06-03 00:00:00

abstract：BACKGROUND:Lassa hemorrhagic fever (LHF) is a neglected tropical disease with significant impact on the health care system, society, and economy of Western and Central African nations where it is endemic. With a high rate of infection that may lead to morbidity and mortality, understanding how the virus interacts with ...

journal_title：Virology journal

authors： Branco LM,Grove JN,Moses LM,Goba A,Fullah M,Momoh M,Schoepp RJ,Bausch DG,Garry RF

更新日期：2010-11-09 00:00:00

abstract：BACKGROUND:The amino terminus of the tobacco etch virus (TEV) capsid protein is located on the external surface of infectious TEV particles, as proposed by previous studies and an in silico model. The epsilon amino groups on the exposed lysine residues are available for chemical conjugation to any given protein, and ca...

journal_title：Virology journal

authors： Manuel-Cabrera CA,Márquez-Aguirre A,Rodolfo HG,Ortiz-Lazareno PC,Chavez-Calvillo G,Carrillo-Tripp M,Silva-Rosales L,Gutiérrez-Ortega A

更新日期：2012-03-27 00:00:00

abstract：BACKGROUND:HIV-1 entry into cells is a multifaceted process involving target cell CD4 and the chemokine receptors, CXCR4 or CCR5. The lipid composition of the host cell plays a significant role in the HIV fusion process as it orchestrates the appropriate disposition of CD4 and co-receptors required for HIV-1 envelope g...

journal_title：Virology journal

authors： Ablan S,Rawat SS,Viard M,Wang JM,Puri A,Blumenthal R

更新日期：2006-12-22 00:00:00

abstract：BACKGROUND:Nuclear factor-kappaB (NF-κB) is an inducible transcription factor that plays a key role in inflammation and immune responses, as well as in the regulation of cell proliferation and survival. Previous studies by our group and others have demonstrated that porcine reproductive and respiratory syndrome virus (...

journal_title：Virology journal

authors： Fang Y,Fang L,Wang Y,Lei Y,Luo R,Wang D,Chen H,Xiao S

更新日期：2012-04-30 00:00:00

abstract：BACKGROUND:Sheeppox (SPP) and goatpox (GTP) caused by sheeppox virus (SPPV) and goatpox virus (GTPV), respectively of the genus Capripoxvirus in the family Poxviridae, are severely afflicting small ruminants' production systems in Africa and Asia. In endemic areas, SPP and GTP are controlled using vaccination with live...

journal_title：Virology journal

authors： Chibssa TR,Grabherr R,Loitsch A,Settypalli TBK,Tuppurainen E,Nwankpa N,Tounkara K,Madani H,Omani A,Diop M,Cattoli G,Diallo A,Lamien CE

更新日期：2018-04-02 00:00:00

abstract：BACKGROUND:Zika virus (ZIKV) is a major human pathogen and member of the Flavivirus genus. Previous studies have identified neutralizing antibodies from Zika patients that bind to quaternary epitopes across neighboring envelope (E) proteins, called E dimer epitopes (EDE). An asparagine-linked glycan on the "glycan loop...

journal_title：Virology journal

authors： Henderson EA,Tam CC,Cheng LW,Ngono AE,Nguyen AV,Shresta S,McGee M,Padgett H,Grill LK,Martchenko Shilman M

更新日期：2020-03-31 00:00:00

abstract：BACKGROUND:The global spread of the highly pathogenic avian influenza H5N1 virus has stimulated interest in a better understanding of the mechanisms of H5N1 dispersal, including the potential role of migratory birds as carriers. Although wild birds have been found dead during H5N1 outbreaks, evidence suggests that othe...

journal_title：Virology journal

authors： Ip HS,Flint PL,Franson JC,Dusek RJ,Derksen DV,Gill RE Jr,Ely CR,Pearce JM,Lanctot RB,Matsuoka SM,Irons DB,Fischer JB,Oates RM,Petersen MR,Fondell TF,Rocque DA,Pedersen JC,Rothe TC

更新日期：2008-06-04 00:00:00