Human platelets express CAR with localization at the sites of intercellular interaction.

abstract：BACKGROUND:Hepatitis C virus roots a chronic liver disease. Currently approved treatment strategy includes administration of alpha interferon and ribavirin combined therapy for 24-48 weeks. One of the predictor of sustained virological response is an early virological response to treatment characterized as rapid respon...

journal_title：Virology journal

authors： Akram M,Idrees M,Hussain A,Afzal S,Ilyas M,Zafar S,Aftab M,Badar S,Khubaib B

更新日期：2011-05-23 00:00:00

abstract：BACKGROUND:One requisite of quantitative reverse transcription PCR (qRT-PCR) is to normalise the data with an internal reference gene that is invariant regardless of treatment, such as virus infection. Several studies have found variability in the expression of commonly used housekeeping genes, such as beta-actin (ACTB...

journal_title：Virology journal

authors： Kuchipudi SV,Tellabati M,Nelli RK,White GA,Perez BB,Sebastian S,Slomka MJ,Brookes SM,Brown IH,Dunham SP,Chang KC

更新日期：2012-10-08 00:00:00

abstract：BACKGROUND:Hepatitis B virus (HBV) infection is a blood borne infectious disease that affects the liver. Human bone marrow mesenchymal stem cells (BMSCs) may serve as a cell source for adult stem cell transplantation in liver repair. However, the susceptibility of human BMSCs to HBV infection is poorly understood. The ...

journal_title：Virology journal

authors： Ma R,Xing Q,Shao L,Wang D,Hao Q,Li X,Sai L,Ma L

更新日期：2011-10-31 00:00:00

abstract：BACKGROUND:RNA viruses are characterized by high rate of mutations mainly due to the lack of proofreading repair activities associated with its RNA-dependent RNA-polymerase (RdRp). In case of arboviruses, this phenomenon has lead to the existence of mixed population of genomic variants within the host called quasi-spec...

journal_title：Virology journal

authors： Jain J,Mathur K,Shrinet J,Bhatnagar RK,Sunil S

更新日期：2016-06-02 00:00:00

abstract：BACKGROUND:A serological method to simultaneously detect antibodies against infectious laryngotracheitis virus (ILTV) and infectious bronchitis virus (IBV) is imperative for the differential diagnosis and evaluation of antibodies titers after vaccination. METHOD:The microspheres coated with purified recombinant glycop...

journal_title：Virology journal

authors： Wang H,Cong F,Guan J,Xiao L,Zhu Y,Lian Y,Huang R,Chen M,Guo P

更新日期：2018-09-21 00:00:00

abstract：BACKGROUND:The high genetic diversity of HIV-1 has been shown to influence the global distribution, disease progression, treatment success, and the development of an effective vaccine. Despite the low HIV prevalence in Cameroon, all the major HIV subtypes alongside several circulating recombinant forms (CRFs) and uniqu...

journal_title：Virology journal

authors： Abongwa LE,Nyamache AK,Torimiro JN,Okemo P,Charles F

更新日期：2019-08-15 00:00:00

abstract：BACKGROUND:Swine-origin virus infection spreading widely could cause significant economic loss to porcine industry. Novel antiviral agents need to be developed to control this situation. METHODS:In this study, we evaluated the activities of five broad-spectrum antimicrobial peptides (AMPs) against several important sw...

journal_title：Virology journal

authors： Hu H,Guo N,Chen S,Guo X,Liu X,Ye S,Chai Q,Wang Y,Liu B,He Q

更新日期：2019-07-31 00:00:00

abstract：:Viral diseases constitute obstacles to pepper production in the world. In Nigeria, pepper plants are primarily affected by pepper veinal mottle virus (PVMV), Cucumber mosaic virus (CMV), Pepper leaf curl Virus (TLCV), Tobacco mosaic virus (TMV), Pepper mottle virus (PMV) and a host of other viruses. The experiment was...

journal_title：Virology journal

authors： Arogundade O,Balogun OS,Kareem KT

更新日期：2012-04-11 00:00:00

abstract：BACKGROUND:Rotavirus (RV) is the main cause of severe gastroenteritis in children. An effective vaccination regime against RV can substantially reduce morbidity and mortality. Previous studies have demonstrated the efficacy of virus-like particles formed by RV VP2 and VP6 (VLP2/6), as well as that of recombinant adenov...

journal_title：Virology journal

authors： Zhou H,Guo L,Wang M,Qu J,Zhao Z,Wang J,Hung T

更新日期：2011-01-05 00:00:00

abstract：BACKGROUND:The gut microbiome is closely associated with the health of the host; although the interaction between the bacterial microbiome and the whole virome has rarely been studied, it is likely of medical importance. Examination of the interactions between the gut bacterial microbiome and virome of rhesus monkey wo...

journal_title：Virology journal

authors： Li H,Li H,Wang J,Guo L,Fan H,Zheng H,Yang Z,Huang X,Chu M,Yang F,He Z,Li N,Yang J,Wu Q,Shi H,Liu L

更新日期：2019-08-19 00:00:00

abstract：BACKGROUND:Human pegivirus (HPgV) is structurally similar to hepatitis C virus (HCV) and was discovered 20 years ago. Its distribution, natural history and exact rule of this viral group in human hosts remain unclear. Our aim was to determine, by deep next-generation sequencing (NGS), the entire genome sequence of HPgV...

journal_title：Virology journal

authors： Soliman HK,Abouelhoda M,El Rouby MN,Ahmed OS,Esmat G,Hassan ZK,Hafez MM,Mehaney DA,Selvaraju M,Darwish RK,Osman YA,Zekri AN

更新日期：2019-11-11 00:00:00

abstract：:A tenuivirus, referred to here as JKI 29327, was isolated from a black medic (Medicago lupulina) plant collected in Austria. The virus was mechanically transmitted to Nicotiana benthamiana, M. lupulina, M. sativa, Pisum sativum and Vicia faba. The complete genome was determined by high throughput sequencing. The genom...

journal_title：Virology journal

authors： Gaafar YZA,Richert-Pöggeler KR,Sieg-Müller A,Lüddecke P,Herz K,Hartrick J,Seide Y,Vetten HJ,Ziebell H

更新日期：2019-07-05 00:00:00

abstract：:Guards of Cyprian honey bee colonies, Apis mellifera cypria, display a great defensive behaviour against hornets' attacks. The deformed wing virus (DWV) and the kakugo virus (KV) genomes are very similar, but unlike KV, the presence of DWV is not related to honey bees' aggressiveness. This discrepancy is further discu...

journal_title：Virology journal

authors： Rortais A,Tentcheva D,Papachristoforou A,Gauthier L,Arnold G,Colin ME,Bergoin M

更新日期：2006-08-30 00:00:00

abstract：BACKGROUND:There are over 100 known human adenovirus (HAdV) types, which are able to cause a broad variety of different self-limiting but also lethal diseases especially in immunocompromised patients. Only limited information about the pathogenesis and biology of the majority of these virus types is available. In the p...

journal_title：Virology journal

authors： Mese K,Bunz O,Schellhorn S,Volkwein W,Jung D,Gao J,Zhang W,Baiker A,Ehrhardt A

更新日期：2020-04-09 00:00:00

abstract：BACKGROUND:In China, more than 20 million patients with chronic hepatitis B need antiviral treatment. Side effects of antiviral treatment such as renal complications can be problematic, particularly in an aging population. METHODS:The data were retrospectively extracted from the hospital medical charts of five centers...

journal_title：Virology journal

authors： Gu J,Yu G,Zhang X,Zhang S,Cai H,Ye C,Yang Y,Li D,Tong Z,Shen H,Chen H,Ding F,Lai X,Liu J,Xu M,Wu W

更新日期：2021-01-13 00:00:00

abstract：BACKGROUND:Human cytomegalovirus (HCMV) is the most common cause of intrauterine infections worldwide. The toll-like receptors (TLRs) have been reported as important factors in immune response against HCMV. Particularly, TLR2, TLR4 and TLR9 have been shown to be involved in antiviral immunity. Evaluation of the role of...

journal_title：Virology journal

authors： Wujcicka W,Paradowska E,Studzińska M,Wilczyński J,Nowakowska D

更新日期：2017-03-24 00:00:00

abstract：:The original version of the acknowledgement unfortunately contained a mistake. ...

journal_title：Virology journal

authors： Signer J,Jonsdottir HR,Albrich WC,Strasser M,Züst R,Ryter S,Ackermann-Gäumann R,Lenz N,Siegrist D,Suter A,Schoop R,Engler OB

更新日期：2020-11-09 00:00:00

abstract：BACKGROUND:West Nile virus (WNV) and Usutu virus (USUV), both belonging to the genus Flavivirus, are emerging in Italy as important human and animal pathogens. Migratory birds are involved in the spread of Flaviviruses over long distances, particularly from Africa to Europe. Once introduced, these viruses can be furthe...

journal_title：Virology journal

authors： Grisenti M,Arnoldi D,Rizzolli F,Giacobini M,Bertolotti L,Rizzoli A

更新日期：2013-10-11 00:00:00

abstract：:This study describes the prevalence of culture-positive adenovirus serotypes in culture-positive respiratory specimens sent to the Central Public Health Laboratory, Toronto, Ontario, Canada for the period September 2007-June 2008. Total nucleic acid was extracted from virus cultures using an automated extraction metho...

journal_title：Virology journal

authors： Yeung R,Eshaghi A,Lombos E,Blair J,Mazzulli T,Burton L,Drews SJ

更新日期：2009-01-26 00:00:00

abstract：BACKGROUND:The ESCRT (endosomal sorting complex required for transport) machinery functions to sort cellular receptors into the lumen of the multivesicular body (MVB) prior to lysosomal degradation. ESCRT components can also be recruited by enveloped viruses to sites of viral assembly where they have been proposed to m...

journal_title：Virology journal

authors： Valiathan RR,Resh MD

更新日期：2008-02-11 00:00:00

abstract：:Marek's disease is a highly contagious disease of poultry characterized by rapid-on set of T-cell lymphomas, which is caused by Marek's disease virus (MDV), but its pathogenic mechanism is still not very clear. Recently, some new progress were achieved in molecular character of MDV. Along with the genomic sequencing o...

journal_title：Virology journal

authors： Tian M,Zhao Y,Shi M,Lin Y,Zou N,Liu P,Wen X,Cao S,Huang Y

更新日期：2010-12-23 00:00:00

abstract：:Hairpin RNAs have been used to confer resistance to viruses in plants through RNA silencing. However, it has not been demonstrated that RNA silencing was effective against inoculation by aphids of non-persistently transmitted viruses, the major route of plant virus spread in nature. As a proof-of-principle strategy, w...

journal_title：Virology journal

authors： Vargas M,Martínez-García B,Díaz-Ruíz JR,Tenllado F

更新日期：2008-03-19 00:00:00

abstract：:The most common etiologic agents causing chronic hepatitis are hepatitis C and B viruses (HCV and HBV, respectively). Chronic infection caused by HCV is considered one of the major causative agents of liver cirrhosis and hepatocellular carcinoma worldwide. In combination with the increasing rate of new HCV infections,...

journal_title：Virology journal

authors： Hoffmann TW,Duverlie G,Bengrine A

更新日期：2012-06-12 00:00:00

abstract：BACKGROUND:Human caliciviruses (HuCV) are emerging enteric pathogens that are a common cause of diarrhea in humans worldwide. Due to the paucity of information on the molecular characterization of HuCV circulating in Mexico, the aim of this work was to investigate the diversity and molecular epidemiology of the HuCV in...

journal_title：Virology journal

authors： Gómez-Santiago F,Ribas-Aparicio RM,García-Lozano H

更新日期：2012-02-23 00:00:00

abstract：BACKGROUND:Hepatitis B virus (HBV) infection is a serious health problem worldwide. Treatment recommendation and response are mainly indicated by viral load, e antigen (HBeAg) seroconversion, and ALT levels. The S antigen (HBsAg) seroconversion is much less frequent. Since HBeAg can be negative in the presence of high ...

journal_title：Virology journal

authors： Lian M,Zhou X,Wei L,Qiu S,Zhou T,Li L,Gu X,Luo M,Zheng X

更新日期：2007-09-24 00:00:00

abstract：BACKGROUND:Human enterovirus 71 (EV-71) is known of having caused numerous outbreaks of hand-foot-mouth disease, and other clinical manifestations globally. In 2008, 989 EV-71 strains were isolated in Taiwan. RESULTS:In this study, the genetic and antigenic properties of these strains were analyzed and the genetic div...

journal_title：Virology journal

authors： Huang YP,Lin TL,Hsu LC,Chen YJ,Tseng YH,Hsu CC,Fan WB,Yang JY,Chang FY,Wu HS

更新日期：2010-10-20 00:00:00

abstract：BACKGROUND:SEN virus is a blood-borne, circular ssDNA virus and possessing nine genotypes (A to I). Among nine genotypes, SENV-D and SENV-H genotypes have the strong link with patients with unknown (none-A to E) hepatitis infections. Infection with blood-borne viruses is the second important cause of death in thalassem...

journal_title：Virology journal

authors： Karimi-Rastehkenari A,Bouzari M

更新日期：2010-01-02 00:00:00

abstract：:During the outbreak of SARS in 2002/3, a prototype virus was isolated from a patient in Frankfurt/Germany (strain Frankfurt-1). As opposed to all other SARS-Coronavirus strains, Frankfurt-1 has a 45-nucleotide deletion in the transmembrane domain of its ORF 7b protein. When over-expressed in HEK 293 cells, the full-le...

journal_title：Virology journal

authors： Pfefferle S,Krähling V,Ditt V,Grywna K,Mühlberger E,Drosten C

更新日期：2009-08-24 00:00:00

abstract：:Remarkable progress has been made during the past ten years in elucidating the structure of the bacteriophage T4 tail by a combination of three-dimensional image reconstruction from electron micrographs and X-ray crystallography of the components. Partial and complete structures of nine out of twenty tail structural p...

journal_title：Virology journal

authors： Leiman PG,Arisaka F,van Raaij MJ,Kostyuchenko VA,Aksyuk AA,Kanamaru S,Rossmann MG

更新日期：2010-12-03 00:00:00

abstract：BACKGROUND:Epstein-Barr virus (EBV) is associated with 20-40% of Hodgkin's Lymphoma (HL) cases. EBV-encoded latent membrane protein 1 (LMP1) is a well-known oncogenic protein and two C-terminal deletion variants, del30-LMP1 and del69-LMP1, have been described in animal models to be more tumorigenic than the wild-type f...

journal_title：Virology journal

authors： Sueur C,Lupo J,Mas P,Morand P,Boyer V

更新日期：2014-05-19 00:00:00