Overexpression of Adenosine A2A Receptors in Rats: Effects on Depression, Locomotion, and Anxiety.

abstract：:Background: Inpatient mental health wards are reported by many consumers to be custodial, unsafe, and lacking in therapeutic relationships. These consumer experiences are concerning, given international policy directives requiring recovery-oriented practice. Safewards is both a model and a suite of interventions desig...

journal_title：Frontiers in psychiatry

authors： Fletcher J,Buchanan-Hagen S,Brophy L,Kinner SA,Hamilton B

更新日期：2019-07-09 00:00:00

abstract：Background:Nonsuicidal self-injury (NSSI) is highly prevalent in clinical and non-clinical populations of adolescents. Several studies have supported both the distinction and the strong association between NSSI and suicidal behavior. Although there is a great deal of data on the role of life events in both suicidal beh...

journal_title：Frontiers in psychiatry

authors： Horváth LO,Győri D,Komáromy D,Mészáros G,Szentiványi D,Balázs J

更新日期：2020-05-06 00:00:00

abstract：INTRODUCTION:Ruminative (abstract verbal) processing during recall of aversive autobiographical memories may serve to dampen their short-term affective impact. Experimental studies indeed demonstrate that verbal processing of non-autobiographical material and positive autobiographical memories evokes weaker affective r...

journal_title：Frontiers in psychiatry

authors： Slofstra C,Eisma MC,Holmes EA,Bockting CLH,Nauta MH

更新日期：2017-05-30 00:00:00

abstract：:Abnormal amplitude of low-frequency fluctuation has been implicated in heroin addiction. However, previous studies lacked consistency and didn't consider the impact of confounding factors such as methadone and alcohol. Fifty-one heroin-dependent (HD) individuals and 40 healthy controls underwent resting-state function...

journal_title：Frontiers in psychiatry

authors： Luo J,Yang R,Yang W,Duan C,Deng Y,Zhang J,Chen J,Liu J

更新日期：2020-07-03 00:00:00

abstract：:Objective: To analyze the predictive value of antepartum vulnerability factors, such as social support, coping, history of psychiatric disease, and fear of childbirth, and intrapartum events on the development of symptoms of postpartum posttraumatic stress disorder (PP-PTSD) in women with a traumatic childbirth experi...

journal_title：Frontiers in psychiatry

authors： van Heumen MA,Hollander MH,van Pampus MG,van Dillen J,Stramrood CAI

更新日期：2018-07-31 00:00:00

abstract：:Individuals with schizophrenia, particularly those with passivity symptoms, may not feel in control of their actions, believing them to be controlled by external agents. Cognitive operations that contribute to these symptoms may include abnormal processing in agency as well as body representations that deal with body ...

journal_title：Frontiers in psychiatry

authors： Graham KT,Martin-Iverson MT,Holmes NP,Jablensky A,Waters F

更新日期：2014-09-10 00:00:00

abstract：Background:In the Corona Virus Disease 2019 (COVID-19) pandemic, the primary problem is respiratory-related, but there also is increasing evidence of central nervous system (CNS) involvement. This study aims to summarize the literature on neurological manifestations of COVID-19, underlying mechanisms of CNS involvement...

journal_title：Frontiers in psychiatry

authors： Wenting A,Gruters A,van Os Y,Verstraeten S,Valentijn S,Ponds R,de Vugt M

更新日期：2020-08-21 00:00:00

abstract：UNLABELLED:Collecting information about the prevalence of cannabis use is necessary but not sufficient for understanding the size, dynamics, and outcomes associated with cannabis markets. This paper uses two data sets describing cannabis consumption in the United States and Europe to highlight (1) differences in infere...

journal_title：Frontiers in psychiatry

authors： Burns RM,Caulkins JP,Everingham SS,Kilmer B

更新日期：2013-11-06 00:00:00

abstract：:Attention deficit hyperactivity disorder (ADHD) is a disorder most frequently diagnosed in children and adolescents. Although ADHD can be effectively treated with psychostimulants, a significant proportion of patients discontinue treatment because of adverse events or insufficient improvement of symptoms. In addition,...

journal_title：Frontiers in psychiatry

authors： Sierawska A,Prehn-Kristensen A,Moliadze V,Krauel K,Nowak R,Freitag CM,Siniatchkin M,Buyx A

更新日期：2019-05-16 00:00:00

abstract：:The complement system consists of more than 30 proteins that have long been known to participate to the immune defence against pathogens and to the removal of damaged cells. Their role, however, extends beyond immunity and clearance of altered "self" components in the periphery. In particular, complement proteins can ...

journal_title：Frontiers in psychiatry

authors： Druart M,Le Magueresse C

更新日期：2019-08-21 00:00:00

abstract：:Introduction: Recent research in Western countries has indicated that family interventions in schizophrenia and other psychotic disorders can reduce patient relapse and improve medication compliance. Few studies have addressed Chinese and Asian populations. This study tested the long-term effects of a 9-month family-l...

journal_title：Frontiers in psychiatry

authors： Chien WT,Bressington D,Chan SWC

更新日期：2018-12-18 00:00:00

abstract：:Studies utilizing functional magnetic resonance imaging (fMRI) cue-reactivity paradigms have demonstrated that short-term abstinent or current methamphetamine (MA) users have increased brain activity in the ventral striatum, caudate nucleus and medial frontal cortex, when exposed to MA-related visual cues. However, pa...

journal_title：Frontiers in psychiatry

authors： Huang S,Zhang Z,Dai Y,Zhang C,Yang C,Fan L,Liu J,Hao W,Chen H

更新日期：2018-04-19 00:00:00

abstract：:Background: Recent models of eating disorders (EDs) have proposed social and emotional difficulties as key factors in the development and maintenance of the illness. While a number of studies have demonstrated difficulties in theory of mind and emotion recognition, little is known about empathic abilities in those wit...

journal_title：Frontiers in psychiatry

authors： Kerr-Gaffney J,Harrison A,Tchanturia K

更新日期：2019-03-04 00:00:00

abstract：Background:The worldwide coronavirus outbreak has put hospital workers under extreme stress with possible mental health problems. In this context, we decided to rapidly design and implement a psychological support system for all hospital workers in Paris during the Covid-19 outbreak. Methods:We built a hotline in 3 da...

journal_title：Frontiers in psychiatry

authors： Geoffroy PA,Le Goanvic V,Sabbagh O,Richoux C,Weinstein A,Dufayet G,Lejoyeux M

更新日期：2020-05-28 00:00:00

abstract：BACKGROUND:Electroconvulsive therapy (ECT) is effective in the treatment of major depressive disorder and schizophrenia in patients who are drug-naïve or less-receptive to antipsychotic drugs. Several studies have discussed the correlation between patient characteristics, input-current volume, and seizure duration. Acc...

journal_title：Frontiers in psychiatry

authors： Wang CC,Lin CH,Chiu YC,Tseng CC

更新日期：2013-12-23 00:00:00

abstract：:Previous studies have reported an association between verbal abuse in early childhood and structural and functional alterations in the young adult brain, supporting the existence of critical periods in human brain development. In addition, exposure to verbal abuse in early childhood is strongly correlated with lifetim...

journal_title：Frontiers in psychiatry

authors： Shin DW,Yoon T,Jeong B

更新日期：2019-04-16 00:00:00

abstract：INTRODUCTION:Despite the importance of dopamine neurotransmission in schizophrenia, very few studies have addressed anomalies in the mesencephalic dopaminergic neurons of the substantia nigra/ventral tegmental area (SN/VTA). Tyrosine hydroxylase (TH) is the rate-limiting enzyme for the production of dopamine, and a pos...

journal_title：Frontiers in psychiatry

authors： Perez-Costas E,Melendez-Ferro M,Rice MW,Conley RR,Roberts RC

更新日期：2012-04-09 00:00:00

abstract：:We use auditory verbal hallucinations (AVH) to illustrate the challenges in defining and assessing target engagement in the context of transcranial direct current stimulation (tDCS) for psychiatric disorders. We defined the target network as the cluster of regions of interest (ROIs) that are consistently implicated in...

journal_title：Frontiers in psychiatry

authors： Lee WH,Kennedy NI,Bikson M,Frangou S

更新日期：2018-02-22 00:00:00

abstract：:Butyrylcholinesterase (BChE) efficiently hydrolyzes acetylcholine (ACh) at high concentrations when acetylcholinesterase (AChE) is substrate-inhibited. Recent studies have shown that BChE also has a function that is independent of ACh, but it has not been fully explored. Low BChE expression is accompanied with higher ...

journal_title：Frontiers in psychiatry

authors： Chen S,Lin Z,Tan KL,Chen R,Su W,Zhao H,Tan Q,Tan W

更新日期：2020-09-11 00:00:00

abstract：:This hypothesis and theory paper presents a pragmatic framework to help bridge the clinical presentation and neuroscience of intrusive memories following psychological trauma. Intrusive memories are a hallmark symptom of post-traumatic stress disorder (PTSD). However, key questions, including those involving etiology,...

journal_title：Frontiers in psychiatry

authors： Clark IA,Mackay CE

更新日期：2015-07-22 00:00:00

abstract：:Introduction: People with psychosis show impairments in cognitive flexibility, a phenomenon that is still poorly understood. In this study, we tested if there were differences in cognitive and metacognitive processes related to rigidity in patients with psychosis. We compared individuals with dichotomous interpersonal...

journal_title：Frontiers in psychiatry

authors： García-Mieres H,Usall J,Feixas G,Ochoa S

更新日期：2020-11-26 00:00:00

abstract：:Third-generation neuroimaging research has been enriched by advances in magnetic resonance spectroscopy (MRS) measuring the concentration of important neurotrasmitters, such as the inhibitory amino acid GABA. Here, we performed a systematic mini-review on brain MRS studies measuring GABA concentration in patients affe...

journal_title：Frontiers in psychiatry

authors： Chiapponi C,Piras F,Piras F,Caltagirone C,Spalletta G

更新日期：2016-04-19 00:00:00

abstract：:Over half of those diagnosed with post-traumatic stress disorder (PTSD) have comorbid major depressive disorder (MDD), and rates are even higher among military veterans. Transcranial magnetic stimulation (TMS) may be a safe and efficacious treatment for PTSD, both with and without comorbid MDD. Still, the mechanism of...

journal_title：Frontiers in psychiatry

authors： Petrosino NJ,Zandvakili A,Carpenter LL,Philip NS

更新日期：2018-11-20 00:00:00

abstract：:Background: Several studies have shown a positive association between anxiety and obesity, particularly in women. We aimed to study whether sex hormone alterations related to obesity might play a role in this association. Patients and methods: Data for this study were obtained from a population-based cohort study (the...

journal_title：Frontiers in psychiatry

authors： Stanikova D,Luck T,Pabst A,Bae YJ,Hinz A,Glaesmer H,Stanik J,Sacher J,Engel C,Enzenbach C,Wirkner K,Ceglarek U,Thiery J,Kratzsch J,Riedel-Heller SG

更新日期：2019-07-04 00:00:00

abstract：:A small number of severely and persistently mentally ill in-patients awaiting residential or long-stay facilities represent an obstacle to the efficient utilization of acute care beds. These facilities are costly and currently reputed to be contrary to recovery principles. In 2013, all acute psychiatric care wards in ...

journal_title：Frontiers in psychiatry

authors： Rapisarda F,Felx A,Gagnon S,De Benedictis L,Luyet A,Boutin M,Corbière M,Lesage A

更新日期：2020-04-07 00:00:00

abstract：:There is accruing evidence of cerebellar abnormalities in schizophrenia. The theory of cognitive dysmetria considers cerebellar dysfunction a key component of schizophrenia. Delay eyeblink conditioning (EBC), a cerebellar-dependent translational probe, is a behavioral index of cerebellar integrity. The circuitry under...

journal_title：Frontiers in psychiatry

authors： Kent JS,Bolbecker AR,O'Donnell BF,Hetrick WP

更新日期：2015-12-18 00:00:00

abstract：Introduction:Visual impairment (VI) is associated with a variety of comorbidities including physical and mental health in industrial countries. Our aim is to examine associations between self-reported impairment and depressive symptoms in the German population. Methods:The point prevalence of self-reported VI in Germa...

journal_title：Frontiers in psychiatry

authors： Schuster AK,Tesarz J,Rezapour J,Beutel ME,Bertram B,Pfeiffer N

更新日期：2018-04-09 00:00:00

abstract：BACKGROUND:Identifying objective and accurate markers of cocaine dependence (CD) can innovate its prevention and treatment. Existing evidence suggests that CD is characterized by a wide range of cognitive deficits, most notably by increased impulsivity. Impulsivity is multidimensional and it is unclear which of its var...

journal_title：Frontiers in psychiatry

authors： Ahn WY,Ramesh D,Moeller FG,Vassileva J

更新日期：2016-03-10 00:00:00

abstract：Objectives:Deviations from typical word use have been previously reported in clinical depression, but language patterns of mild depression (MD), as distinct from normal sadness (NS) and euthymic state, are unknown. In this study, we aimed to apply the linguistic approach as an additional diagnostic key for understandin...

journal_title：Frontiers in psychiatry

authors： Smirnova D,Cumming P,Sloeva E,Kuvshinova N,Romanov D,Nosachev G

更新日期：2018-04-10 00:00:00

abstract：:Background: Major depressive disorder (MDD) is associated with a wide range of cognitive deficits. However, it remains unclear whether there will be a major cognitive deficit independently caused by depression at acute episodes of MDD. Method: A comprehensive neurocognitive test battery was used to assess the executiv...

journal_title：Frontiers in psychiatry

authors： Liu J,Dong Q,Lu X,Sun J,Zhang L,Wang M,Wan P,Guo H,Zhao F,Ju Y,Yan D,Li H,Fang H,Guo W,Liao M,Zhang X,Zhang Y,Liu B,Li L

更新日期：2019-11-12 00:00:00