Dopamine pathology in schizophrenia: analysis of total and phosphorylated tyrosine hydroxylase in the substantia nigra.

abstract：:Our study aims to explore the risk factors for suicidal ideation and their interaction among the elderly in nursing homes in Hunan province, China. A cross-sectional study was conducted among the elderly in nursing homes in Hunan Province. Twenty-four nursing homes were selected by multistage cluster random sampling, ...

journal_title：Frontiers in psychiatry

authors： Nie Y,Hu Z,Zhu T,Xu H

更新日期：2020-04-30 00:00:00

abstract：:Introduction: Although binge eating disorder (BED) is an eating disorder and obesity is a clinical disease, it is known that both conditions present overlapped symptoms related to, at least partially, the disruption of homeostatic and hedonistic eating behavior pathways. Therefore, the understanding of neural substrat...

journal_title：Frontiers in psychiatry

authors： Antunes LC,Elkfury JL,Parizotti CS,Brietzke AP,Bandeira JS,Torres ILDS,Fregni F,Caumo W

更新日期：2020-10-14 00:00:00

abstract：:Transmissible spongiform encephalopathies (TSE) are characterized by the misfolding of the host encoded prion protein (PrP(C)) into a pathogenic isoform (PrP(Sc)) which leads to the accumulation of β-sheet-rich fibrils and subsequent loss of neurons and synaptic functions. Although many compounds have been identified ...

journal_title：Frontiers in psychiatry

authors： Eiden M,Leidel F,Strohmeier B,Fast C,Groschup MH

更新日期：2012-02-17 00:00:00

abstract：:Adenosine A2A receptors (A2AR) are a sub-type of receptors enriched in basal ganglia, activated by the neuromodulator adenosine, which interact with dopamine D2 receptors. Although this reciprocal antagonistic interaction is well-established in motor function, the outcome in dopamine-related behaviors remains uncertai...

journal_title：Frontiers in psychiatry

authors： Coelho JE,Alves P,Canas PM,Valadas JS,Shmidt T,Batalha VL,Ferreira DG,Ribeiro JA,Bader M,Cunha RA,do Couto FS,Lopes LV

更新日期：2014-06-13 00:00:00

abstract：Background:From birth, the human propensity to selectively attend and respond to critical super-stimuli forms the basis of future socio-emotional development and health. In particular, the first super-stimuli to preferentially engage and elicit responses in the healthy newborn are the physical touch, voice and face/eye...

journal_title：Frontiers in psychiatry

authors： Doyle FL,Mendoza Diaz A,Eapen V,Frick PJ,Kimonis ER,Hawes DJ,Moul C,Richmond JL,Mehta D,Sareen S,Morgan BG,Dadds MR

更新日期：2020-06-19 00:00:00

abstract：:Background: People who receive involuntary treatment are some of the most vulnerable in psychiatric services. They are more likely to have poorer social and clinical outcomes and to be disillusioned with and disengaged from care. Research indicates that patients' experience in the first week of involuntary treatment i...

journal_title：Frontiers in psychiatry

authors： Burn E,Conneely M,Leverton M,Giacco D

更新日期：2019-07-04 00:00:00

abstract：:The prevalence of alcohol abuse among patients treated in accident and emergency departments (A&E) is considered as substantial. This paper is a narrative review of studies investigating the effectiveness of brief interventions (BI) for hazardous and harmful alcohol consumption in A&E. A&E departments in hospitals (an...

journal_title：Frontiers in psychiatry

authors： Wojnar M,Jakubczyk A

更新日期：2014-11-03 00:00:00

abstract：:Previous studies have reported an association between verbal abuse in early childhood and structural and functional alterations in the young adult brain, supporting the existence of critical periods in human brain development. In addition, exposure to verbal abuse in early childhood is strongly correlated with lifetim...

journal_title：Frontiers in psychiatry

authors： Shin DW,Yoon T,Jeong B

更新日期：2019-04-16 00:00:00

abstract：STUDY OBJECTIVE:Animal data suggest that Δ(9)-TetraHydroCannabinol (Δ(9)THC) stabilizes autonomic output during sleep, reduces spontaneous sleep-disordered breathing, and blocks serotonin-induced exacerbation of sleep apnea. On this basis, we examined the safety, tolerability, and efficacy of dronabinol (Δ(9)THC), an e...

journal_title：Frontiers in psychiatry

authors： Prasad B,Radulovacki MG,Carley DW

更新日期：2013-01-22 00:00:00

abstract：:Refinements in the methods of diagnosis for psychiatric disorders are critically needed. These new methods should be based on objectively measured brain characteristics that provide clinically useful information. Studying the brain with respect to psychiatric disorders, however, faces numerous challenges. Utilizing te...

journal_title：Frontiers in psychiatry

authors： Kozel FA

更新日期：2010-10-20 00:00:00

abstract：:Over half of those diagnosed with post-traumatic stress disorder (PTSD) have comorbid major depressive disorder (MDD), and rates are even higher among military veterans. Transcranial magnetic stimulation (TMS) may be a safe and efficacious treatment for PTSD, both with and without comorbid MDD. Still, the mechanism of...

journal_title：Frontiers in psychiatry

authors： Petrosino NJ,Zandvakili A,Carpenter LL,Philip NS

更新日期：2018-11-20 00:00:00

abstract：:Background: Young adults regularly using cannabis represent a uniquely vulnerable yet heterogeneous cohort. Few studies have examined user profiles using cannabis use motives and expectations. The association between user profiles and psychosocial functioning among only regular users remains unexplored. This explorati...

journal_title：Frontiers in psychiatry

authors： Amiet D,Youssef GJ,Hagg LJ,Lorenzetti V,Parkes L,Solowij N,Yücel M

更新日期：2020-12-15 00:00:00

abstract：:Disrupted white matter (WM) integrity in the anterior thalamic radiation (ATR) has been identified in individuals with bipolar disorder (BD). We explored whether structural WM aberration in the ATR could be visually evaluated by diffusion tensor tractography (DTT). The study comprised 114 participants, including 57 pa...

journal_title：Frontiers in psychiatry

authors： Niida R,Yamagata B,Niida A,Uechi A,Matsuda H,Mimura M

更新日期：2018-10-24 00:00:00

abstract：:Studies have shown a direct link between memory for emotionally salient experiences and false memories. In particular, emotionally arousing material of negative and positive valence enhanced reality monitoring compared to neutral material since emotional stimuli can be encoded with more contextual details and thereby ...

journal_title：Frontiers in psychiatry

authors： Fairfield B,Altamura M,Padalino FA,Balzotti A,Di Domenico A,Mammarella N

更新日期：2016-11-30 00:00:00

abstract：:The aim of this study is to explore the changes and clinical significance of serum C3, C4, hypersensitive C-reactive protein (hsCRP) and uric acid (UA) in patients of bipolar disorder (BD). In this case-control study, we recruited 141 BD patients from The Second Xiangya Hospital, Central South University, and 151 age ...

journal_title：Frontiers in psychiatry

authors： Yang X,Tao H,Xiao L,Li C,Tang Y,Liu Y

更新日期：2018-08-21 00:00:00

abstract：:Mental imagery, seeing with the mind's eyes, can induce stronger positive as well as negative affect compared to verbal processing. Given this emotion-amplifying effect, it appears likely that mental images play an important role in affective disorders. According to the subcomponents model of depression, depressed moo...

journal_title：Frontiers in psychiatry

authors： Görgen SM,Joormann J,Hiller W,Witthöft M

更新日期：2015-07-07 00:00:00

abstract：:Social cognition is a fundamental ability in human everyday lives. Deficits in social functioning also represent a core aspect of many psychiatric disorders. Yet, despite its significance, deficits in social cognition skills are insufficiently targeted by current treatments. Hallucinogens and entactogens have been sho...

journal_title：Frontiers in psychiatry

authors： Preller KH,Vollenweider FX

更新日期：2019-12-03 00:00:00

abstract：:The view that anatomically distinct memory systems differentially contribute to the development of drug addiction and relapse has received extensive support. The present brief review revisits this hypothesis as it was originally proposed 20 years ago (1) and highlights several recent developments. Extensive research e...

journal_title：Frontiers in psychiatry

authors： Goodman J,Packard MG

更新日期：2016-02-25 00:00:00

abstract：:Inflammation and immune dysregulation could contribute to the pathogenesis of schizophrenia. Osteopontin (OPN) is a cytokine-like glycoprotein involved in inflammation and in modulating immune responses, and it can also directly modify the cytokine expression and survival of microglia. Furthermore, elevated gene expre...

journal_title：Frontiers in psychiatry

authors： Kovács MÁ,Tényi T,Kugyelka R,Prenek L,Hau L,Magyar ÉE,Herold R,Balogh P,Simon D

更新日期：2020-01-23 00:00:00

abstract：:Very-brief, web-based alcohol interventions have great potential due to their convenience, ease of dissemination, and college students' stated preference for this intervention modality. To address the efficacy of these interventions, we conducted a review of the literature to identify randomized controlled trials (RCT...

journal_title：Frontiers in psychiatry

authors： Leeman RF,Perez E,Nogueira C,DeMartini KS

更新日期：2015-09-28 00:00:00

abstract：:HIV-related stigma has been documented as one of the greatest obstacles to reducing HIV spread, engagement in HIV treatment, and poor mental health functioning among people living with HIV (PLWH). Although disclosure is important for people to receive social support, the fear of stigma and discrimination prevents PLWH...

journal_title：Frontiers in psychiatry

authors： Nabunya P,Byansi W,Sensoy Bahar O,McKay M,Ssewamala FM,Damulira C

更新日期：2020-07-31 00:00:00

abstract：AIM:In efforts to develop reliable methods to detect the likelihood of impending suicidal behaviors, we have proposed the following. OBJECTIVE:To gain a deeper understanding of the state of suicide risk by determining the combination of variables that distinguishes between groups with and without suicide risk. METHOD...

journal_title：Frontiers in psychiatry

authors： Morales S,Barros J,Echávarri O,García F,Osses A,Moya C,Maino MP,Fischman R,Núñez C,Szmulewicz T,Tomicic A

更新日期：2017-02-02 00:00:00

abstract：Background:Mobile phone addiction behaviors (MPAB) are extensively associated with several mental and sleep problems. Only a limited number of bidirectional longitudinal papers have focused on this field. This study aimed to examine the bidirectional associations of MPAB with mental distress, sleep disturbances, and sl...

journal_title：Frontiers in psychiatry

authors： Kang Y,Liu S,Yang L,Xu B,Lin L,Xie L,Zhang W,Zhang J,Zhang B

更新日期：2020-07-17 00:00:00

abstract：:Background: Inpatient mental health wards are reported by many consumers to be custodial, unsafe, and lacking in therapeutic relationships. These consumer experiences are concerning, given international policy directives requiring recovery-oriented practice. Safewards is both a model and a suite of interventions desig...

journal_title：Frontiers in psychiatry

authors： Fletcher J,Buchanan-Hagen S,Brophy L,Kinner SA,Hamilton B

更新日期：2019-07-09 00:00:00

abstract：:Japan recently ordered a string of death sentences for offenders with mental illness. Based on the verdicts, we describe cases where one or more psychiatrists conducted psychiatric evaluations for several months and testified in lay judge courts. We compared these cases with those in which the death penalty was avoide...

journal_title：Frontiers in psychiatry

authors： Kashiwagi H,Hirabayashi N

更新日期：2018-11-02 00:00:00

abstract：Objective:Insomnia is associated with suicidality, although the mechanisms of this association are unclear. This study sought to replicate previous findings showing that insomnia symptoms but not sleep duration are associated with frequency of suicidal ideation in adults. We further investigated whether depression or s...

journal_title：Frontiers in psychiatry

authors： Simmons Z,Erickson LD,Hedges D,Kay DB

更新日期：2020-09-18 00:00:00

abstract：:The worldwide prevalence of sleep disorders is approximately 50%, with an even higher occurrence in a psychiatric population. Bipolar disorder (BD) is a severe mental illness characterized by shifts in mood and activity. The BD syndrome also involves heterogeneous symptomatology, including cognitive dysfunctions and i...

journal_title：Frontiers in psychiatry

authors： Steardo L Jr,de Filippis R,Carbone EA,Segura-Garcia C,Verkhratsky A,De Fazio P

更新日期：2019-07-18 00:00:00

abstract：BACKGROUND:Electroconvulsive therapy (ECT) is effective in the treatment of major depressive disorder and schizophrenia in patients who are drug-naïve or less-receptive to antipsychotic drugs. Several studies have discussed the correlation between patient characteristics, input-current volume, and seizure duration. Acc...

journal_title：Frontiers in psychiatry

authors： Wang CC,Lin CH,Chiu YC,Tseng CC

更新日期：2013-12-23 00:00:00

abstract：:Eating disorders (EDs) are serious psychopathologies characterized by a persistent disturbance in eating or eating-related behavior. Studies have shown EDs' detrimental consequences not only for patients, but also for their families. Nevertheless, a specific group that has so far been neglected, in both the research a...

journal_title：Frontiers in psychiatry

authors： Maon I,Horesh D,Gvion Y

更新日期：2020-06-30 00:00:00

abstract：:Bipolar disorder (BD) is a leading cause of worldwide disability among mood disorders. Pathological mechanisms are still vastly unclear, and current treatments with conventional medications are often unsatisfactory in maintaining symptoms control and an adequate quality of life. Consequently, current research is focus...

journal_title：Frontiers in psychiatry

authors： Benedetti F,Aggio V,Pratesi ML,Greco G,Furlan R

更新日期：2020-02-26 00:00:00