Enhanced Contextual Fear Memory and Elevated Astroglial Glutamate Synthase Activity in Hippocampal CA1 BChE shRNA Knockdown Mice.

abstract：:The prevalence of alcohol abuse among patients treated in accident and emergency departments (A&E) is considered as substantial. This paper is a narrative review of studies investigating the effectiveness of brief interventions (BI) for hazardous and harmful alcohol consumption in A&E. A&E departments in hospitals (an...

journal_title：Frontiers in psychiatry

authors： Wojnar M,Jakubczyk A

更新日期：2014-11-03 00:00:00

abstract：:Introduction: Antipsychotic treatment can improve the symptoms of schizophrenia; however, residual symptoms after antipsychotic treatment are frequent. The effects of exercise on the symptoms of schizophrenic patients under antipsychotic treatment are inconclusive. The aim of this randomized case-control study was to ...

journal_title：Frontiers in psychiatry

authors： Wang PW,Lin HC,Su CY,Chen MD,Lin KC,Ko CH,Yen CF

更新日期：2018-05-15 00:00:00

abstract：:Background: Treatment of borderline personality disorder (BPD) in publicly funded mental health services generally use approaches based on medical interventions and generic case management. Specific psychological therapies developed for BPD may be more effective but have rarely been evaluated in routine clinical pract...

journal_title：Frontiers in psychiatry

authors： Carlyle D,Green R,Inder M,Porter R,Crowe M,Mulder R,Frampton C

更新日期：2020-11-12 00:00:00

abstract：:The COVID-19 epidemic has caused increasing public panic and mental health stress. In this study, we explore the prevalence and factors linked to anxiety and depression in hospitalized patients with COVID-19. A total of 144 patients diagnosed with COVID-19 underwent depression and anxiety assessment by using the Hospi...

journal_title：Frontiers in psychiatry

authors： Kong X,Kong F,Zheng K,Tang M,Chen Y,Zhou J,Li Y,Diao L,Wu S,Jiao P,Su T,Dong Y

更新日期：2020-11-20 00:00:00

abstract：:Our study aims to explore the risk factors for suicidal ideation and their interaction among the elderly in nursing homes in Hunan province, China. A cross-sectional study was conducted among the elderly in nursing homes in Hunan Province. Twenty-four nursing homes were selected by multistage cluster random sampling, ...

journal_title：Frontiers in psychiatry

authors： Nie Y,Hu Z,Zhu T,Xu H

更新日期：2020-04-30 00:00:00

abstract：:Attention-deficit/hyperactivity disorder (ADHD) and autism spectrum disorder (ASD) often co-occur and share neurocognitive deficits. One such shared impairment is in duration discrimination. However, no studies using functional magnetic resonance imaging (fMRI) have investigated whether these duration discrimination d...

journal_title：Frontiers in psychiatry

authors： Lukito SD,O'Daly OG,Lythgoe DJ,Whitwell S,Debnam A,Murphy CM,Ashwood K,Stoencheva V,Simonoff E,Rubia K

更新日期：2018-11-14 00:00:00

abstract：Objectives:Many studies reported structural brain changes in patients with alcohol dependence (PADs). However, no studies identified structural correlates of apathy that might aggravate alcohol misuse. Here, we explored regional differences in cortical thickness in PADs relative to healthy controls (HCs), and examined ...

journal_title：Frontiers in psychiatry

authors： Yang K,Yang Q,Niu Y,Fan F,Chen S,Luo X,Tan S,Wang Z,Tong J,Yang F,Le TM,Li CR,Tan Y

更新日期：2020-05-05 00:00:00

abstract：:Abnormalities in EEG gamma band oscillations (GBO, 30-80 Hz) serve as a prominent biomarker of schizophrenia (Sz), associated with positive, negative, and cognitive symptoms. Chronic, subanesthetic administration of antagonists of N-methyl-D-aspartate receptors (NMDAR), such as ketamine, elicits behavioral effects, an...

journal_title：Frontiers in psychiatry

authors： McNally JM,McCarley RW,Brown RE

更新日期：2013-09-17 00:00:00

abstract：:Background: Over the past 15 years, comparative assessments of psychoactive substance harms to both users and others have been compiled by addiction experts. None of these rankings however have included synthetic cannabinoids or non-opioid prescription analgesics (NOAs, e.g., gabapentinoids) despite evidence of increa...

journal_title：Frontiers in psychiatry

authors： Bonnet U,Specka M,Soyka M,Alberti T,Bender S,Grigoleit T,Hermle L,Hilger J,Hillemacher T,Kuhlmann T,Kuhn J,Luckhaus C,Lüdecke C,Reimer J,Schneider U,Schroeder W,Stuppe M,Wiesbeck GA,Wodarz N,McAnally H,Scherbaum N

更新日期：2020-10-26 00:00:00

abstract：:Recent work on the mechanisms underlying auditory verbal hallucination (AVH) has been heavily informed by self-monitoring accounts that postulate defects in an internal monitoring mechanism as the basis of AVH. A more neglected alternative is an account focusing on defects in auditory processing, namely a spontaneous ...

journal_title：Frontiers in psychiatry

authors： Cho R,Wu W

更新日期：2013-11-27 00:00:00

abstract：BACKGROUND:Transcranial direct current stimulation (tDCS) is known to modulate spontaneous neural network excitability. The cognitive improvement observed in previous trials raises the potential of this technique as a possible therapeutic tool for use in attention-deficit/hyperactivity disorder (ADHD) population. Howev...

journal_title：Frontiers in psychiatry

authors： Cosmo C,Ferreira C,Miranda JG,do Rosário RS,Baptista AF,Montoya P,de Sena EP

更新日期：2015-08-04 00:00:00

abstract：:The nature of the relationship between cannabis use (CU) and psychosis is complex and remains unclear. Researchers and clinicians remain divided regarding key issues such as whether or not cannabis is an independent cause of psychosis and schizophrenia. This paper reviews the field in detail, examining questions of ca...

journal_title：Frontiers in psychiatry

authors： Burns JK

更新日期：2013-10-14 00:00:00

abstract：:Voxel-based morphometry (VBM) is a commonly used method to study volumetric variations on a whole brain basis. However, it is often criticized for potential confounds, mainly based on imperfect spatial registration. We therefore aimed to evaluate if VBM and "gold standard" manual volumetry are measuring the same effec...

journal_title：Frontiers in psychiatry

authors： Focke NK,Trost S,Paulus W,Falkai P,Gruber O

更新日期：2014-04-08 00:00:00

abstract：:Previous work has demonstrated that goal-directed control of alcohol-seeking and other drug-related behaviors is reduced following extended self-administration and drug exposure. Here, we examined how the magnitude of stimulus influences on responding changes across similar training and drug exposure. Rats self-admini...

journal_title：Frontiers in psychiatry

authors： Corbit LH,Janak PH

更新日期：2016-10-10 00:00:00

abstract：Background:Previous studies suggested bipolar disorder caused an aberrant alteration in the insular, putamen, and left superior frontal gyrus, which are the main components of the hate circuit. However, the relationship between the hate circuit and the pathophysiologic substrate underlying different phases of bipolar d...

journal_title：Frontiers in psychiatry

authors： Fan Z,Yang J,Zeng C,Xi C,Wu G,Guo S,Xue Z,Liu Z,Tao H

更新日期：2020-10-27 00:00:00

abstract：:Background: Children of parents with a mental illness (COPMI) are more likely to experience negative long-term adversities. However, interventions to support their needs early can significantly enhance adjustment and reduce negative outcomes. Approximately one in four children currently lives with a parent with mental...

journal_title：Frontiers in psychiatry

authors： Christiansen H,Bauer A,Fatima B,Goodyear M,Lund IO,Zechmeister-Koss I,Paul JL

更新日期：2019-04-17 00:00:00

abstract：:The high rate of comorbidity between insomnia and anxiety disorders have been confirmed by previous studies. However, the underlying neurobiological correlates of the relationship between insomnia and anxiety disorders are largely unknown. The aim of the present study was to investigate the effect of insomnia on corti...

journal_title：Frontiers in psychiatry

authors： Huang Z,Zhan S,Chen C,Li N,Ding Y,Hou Y,Wang L,Wang Y

更新日期：2019-01-10 00:00:00

abstract：:Objective: To analyze the predictive value of antepartum vulnerability factors, such as social support, coping, history of psychiatric disease, and fear of childbirth, and intrapartum events on the development of symptoms of postpartum posttraumatic stress disorder (PP-PTSD) in women with a traumatic childbirth experi...

journal_title：Frontiers in psychiatry

authors： van Heumen MA,Hollander MH,van Pampus MG,van Dillen J,Stramrood CAI

更新日期：2018-07-31 00:00:00

abstract：:This paper presents the first systematic case-control study of correlates of mass psychogenic illness (MPI) in an adolescent school population. MPI is generally construed as a dissociative phenomenon spread by social contagion to individuals who are prone to dissociation. We sought to test if the correlates of dissoci...

journal_title：Frontiers in psychiatry

authors： Sapkota RP,Brunet A,Kirmayer LJ

更新日期：2020-11-17 00:00:00

abstract：:The view that anatomically distinct memory systems differentially contribute to the development of drug addiction and relapse has received extensive support. The present brief review revisits this hypothesis as it was originally proposed 20 years ago (1) and highlights several recent developments. Extensive research e...

journal_title：Frontiers in psychiatry

authors： Goodman J,Packard MG

更新日期：2016-02-25 00:00:00

abstract：:Background: Bipolar disorder (BD) has been associated with distributed network disruption, but little is known on how different clinical subtypes, particularly those with an earlier and later onset of disease, are related to connectivity changes in white matter (WM) tracts. Methods: Diffusion tensor imaging (DTI) and ...

journal_title：Frontiers in psychiatry

authors： Alves GS,Knöchel C,Paulitsch MA,Reinke B,Carvalho AF,Feddern R,Prvulovic D,Sudo FK,Pantel J,Reif A,Oertel V

更新日期：2018-10-09 00:00:00

abstract：BACKGROUND:Several lines of evidence implicate dysfunctional neuronal plasticity in the pathophysiology of schizophrenia (SCZ). Aberrant glutamatergic and gamma amino--butyric acid neurotransmission are thought to underlie core cognitive deficits and negative symptoms of SCZ. Non-invasive brain stimulation (NIBS) allow...

journal_title：Frontiers in psychiatry

authors： Bhandari A,Voineskos D,Daskalakis ZJ,Rajji TK,Blumberger DM

更新日期：2016-03-29 00:00:00

abstract：Background:Loss aversion is a central and well operationalized trait behavior that describes the tendency for humans to strongly prefer avoiding losses to making equivalent gains. Human decision-making is thus biased toward safer choices. Aim:The aim of this study was to explore the relationship between loss aversion ...

journal_title：Frontiers in psychiatry

authors： Hadlaczky G,Hökby S,Mkrtchian A,Wasserman D,Balazs J,Machín N,Sarchiapone M,Sisask M,Carli V

更新日期：2018-04-05 00:00:00

abstract：:Bipolar disorder (BD) is a leading cause of worldwide disability among mood disorders. Pathological mechanisms are still vastly unclear, and current treatments with conventional medications are often unsatisfactory in maintaining symptoms control and an adequate quality of life. Consequently, current research is focus...

journal_title：Frontiers in psychiatry

authors： Benedetti F,Aggio V,Pratesi ML,Greco G,Furlan R

更新日期：2020-02-26 00:00:00

abstract：INTRODUCTION:Emerging evidence indicates that nicotine dependence should be measured multidimensionally. A brief version of the Wisconsin Inventory of Smoking Dependence Motives (WISDM) has recently been developed in which the item count has been reduced from 68 to 37. The objectives of this study were to replicate the...

journal_title：Frontiers in psychiatry

authors： Ma JZ,Li MD,Payne TJ

更新日期：2012-04-26 00:00:00

abstract：:Major depressive disorder (MDD) is a complex psychiatric disease requiring multidisciplinary approaches to identify specific risk factors and establish more efficacious treatment strategies. Although the etiology and pathophysiology of MDD are not clear until these days, it is acknowledged that they are almost certain...

journal_title：Frontiers in psychiatry

authors： Shao X,Zhu G

更新日期：2020-05-13 00:00:00

abstract：:Background: Australia is a high-income country with increasing income inequality. It is unclear whether Australia's well-developed mental healthcare system is making a difference to population mental health and the Federal Government has targeted outcomes accountability in service funding strategies. In high-income co...

journal_title：Frontiers in psychiatry

authors： Isaacs AN,Enticott J,Meadows G,Inder B

更新日期：2018-10-26 00:00:00

abstract：:Nonsuicidal Self-Injury (NSSI) and suicidality are common reasons for emergency presentations in child and adolescent psychiatry. Therefore, we focused on reasons for emergency presentations as well as specific characteristics of those presenting with NSSI or suicidality to an emergeny psychiatric service. We analyzed...

journal_title：Frontiers in psychiatry

authors： Franzen M,Keller F,Brown RC,Plener PL

更新日期：2020-01-17 00:00:00

abstract：:Introduction: Previous studies on internet gaming disorder (IGD) have reported an association between personality traits and impulsive or problematic use of the internet or internet games, but the results obtained were inconsistent. Our study's hypothesis was that personality traits are associated with the individual'...

journal_title：Frontiers in psychiatry

authors： Seong W,Hong JS,Kim S,Kim SM,Han DH

更新日期：2019-08-28 00:00:00

abstract：:The significant biochemical and physiological effects of psychological stress are beginning to be recognized as exacerbating common diseases, including osteoporosis. This review discusses the current evidence for psychological stress-associated mental health disorders as risk factors for osteoporosis, the mechanisms t...

journal_title：Frontiers in psychiatry

authors： Kelly RR,McDonald LT,Jensen NR,Sidles SJ,LaRue AC

更新日期：2019-04-09 00:00:00