Abstract:
:Attention deficit hyperactivity disorder (ADHD) is a disorder most frequently diagnosed in children and adolescents. Although ADHD can be effectively treated with psychostimulants, a significant proportion of patients discontinue treatment because of adverse events or insufficient improvement of symptoms. In addition, cognitive abilities that are frequently impaired in ADHD are not directly targeted by medication. Therefore, additional treatment options, especially to improve cognitive abilities, are needed. Because of its relatively easy application, well-established safety, and low cost, transcranial direct current stimulation (tDCS) is a promising additional treatment option. Further research is needed to establish efficacy and to integrate this treatment into the clinical routine. In particular, limited evidence regarding the use of tDCS in children, lack of clear translational guidelines, and general challenges in conducting research with vulnerable populations pose a number of practical and ethical challenges to tDCS intervention studies. In this paper, we identify and discuss ethical issues related to research on tDCS and its potential therapeutic use for ADHD in children and adolescents. Relevant ethical issues in the tDCS research for pediatric ADHD center on safety, risk/benefit ratio, information and consent, labeling problems, and nonmedical use. Following an analysis of these issues, we developed a list of recommendations that can guide clinicians and researchers in conducting ethically sound research on tDCS in pediatric ADHD.
journal_name
Front Psychiatryjournal_title
Frontiers in psychiatryauthors
Sierawska A,Prehn-Kristensen A,Moliadze V,Krauel K,Nowak R,Freitag CM,Siniatchkin M,Buyx Adoi
10.3389/fpsyt.2019.00334subject
Has Abstractpub_date
2019-05-16 00:00:00pages
334issn
1664-0640journal_volume
10pub_type
杂志文章abstract:Background:Previous studies suggested bipolar disorder caused an aberrant alteration in the insular, putamen, and left superior frontal gyrus, which are the main components of the hate circuit. However, the relationship between the hate circuit and the pathophysiologic substrate underlying different phases of bipolar d...
journal_title:Frontiers in psychiatry
pub_type: 杂志文章
doi:10.3389/fpsyt.2020.556126
更新日期:2020-10-27 00:00:00
abstract:Background:Body dysmorphic disorder (BDD) is characterized by an excessive preoccupation with one or more perceived flaws in one's own appearance. Previous studies provided evidence for deficits in configural and holistic processing in BDD. Preliminary evidence suggests abnormalities at an early stage of visual process...
journal_title:Frontiers in psychiatry
pub_type: 杂志文章
doi:10.3389/fpsyt.2020.00302
更新日期:2020-04-24 00:00:00
abstract::With the increase in use of cannabis and its shifting legal status in the United States, cannabis use has become an important research focus. While studies of other drug populations have shown marked increases in risky decision-making, the literature on cannabis users is not as clear. The current study examined the pe...
journal_title:Frontiers in psychiatry
pub_type: 杂志文章
doi:10.3389/fpsyt.2020.599256
更新日期:2020-11-27 00:00:00
abstract::Previous work has demonstrated that goal-directed control of alcohol-seeking and other drug-related behaviors is reduced following extended self-administration and drug exposure. Here, we examined how the magnitude of stimulus influences on responding changes across similar training and drug exposure. Rats self-admini...
journal_title:Frontiers in psychiatry
pub_type: 杂志文章
doi:10.3389/fpsyt.2016.00169
更新日期:2016-10-10 00:00:00
abstract:Background:Chronic insomnia is common in patients with arteriosclerotic cerebral small vessel disease (CSVD) and aggravates the cognitive impairment caused by CSVD. Low-dose trazodone is effective in treating insomnia, but it is unclear whether it can also improve cognitive function in CSVD patients. This study was per...
journal_title:Frontiers in psychiatry
pub_type: 杂志文章
doi:10.3389/fpsyt.2020.00620
更新日期:2020-06-30 00:00:00
abstract::Over the past years, there has been a growing interest in the association between lifestyle psychosocial interventions, severe mental illness, and suicide risk. Patients with severe mental disorders have higher mortality rates, poor health states, and higher suicide risk compared to the general population. Lifestyle b...
journal_title:Frontiers in psychiatry
pub_type: 杂志文章,评审
doi:10.3389/fpsyt.2018.00567
更新日期:2018-11-06 00:00:00
abstract::Background: The clinical and etiological heterogeneity of mood disorders impede identification of effective treatments for the individual patient. This highlights a need for early neuronal and behavioral biomarkers for treatment efficacy, which can provide a basis for more personalized treatments. The present systemat...
journal_title:Frontiers in psychiatry
pub_type: 杂志文章
doi:10.3389/fpsyt.2018.00337
更新日期:2018-07-26 00:00:00
abstract::Social cognition is a fundamental ability in human everyday lives. Deficits in social functioning also represent a core aspect of many psychiatric disorders. Yet, despite its significance, deficits in social cognition skills are insufficiently targeted by current treatments. Hallucinogens and entactogens have been sho...
journal_title:Frontiers in psychiatry
pub_type: 杂志文章,评审
doi:10.3389/fpsyt.2019.00881
更新日期:2019-12-03 00:00:00
abstract::Background: Attention deficit and hyperactivity disorder (ADHD) is one of the most common mental disorders in childhood. Recently, several studies showed the high suicide risk of patients with ADHD; however, most of these studies had a cross-sectional design. Aims: The aim of the current research is to complete a syst...
journal_title:Frontiers in psychiatry
pub_type:
doi:10.3389/fpsyt.2020.557909
更新日期:2020-12-21 00:00:00
abstract:PURPOSE:Excessive daytime sleepiness is highly prevalent in the general population, is the hallmark of narcolepsy, and is linked to significant morbidity. Clinical assessment of sleepiness remains challenging and the common objective multiple sleep latency test (MSLT) and subjective Epworth sleepiness scale (ESS) metho...
journal_title:Frontiers in psychiatry
pub_type: 杂志文章
doi:10.3389/fpsyt.2011.00035
更新日期:2011-06-07 00:00:00
abstract:Background:Cardiovascular disease (CVD) is a major cause of premature death in patients with psychotic disorders, where dyslipidemia occurs frequently. In the pathogenesis of these serious mental disorders, a low-grade inflammation seems to be a possible contributor. Concurrently, systemic inflammation and its interpla...
journal_title:Frontiers in psychiatry
pub_type: 杂志文章
doi:10.3389/fpsyt.2020.00672
更新日期:2020-07-10 00:00:00
abstract::Substance use disorders are chronic, relapsing, and harmful conditions characterized by executive dysfunction. While there are currently no approved pharmacotherapy options for stimulant and cannabis use disorders, there are several evidence-based options available to help reduce symptoms during detoxification and aid...
journal_title:Frontiers in psychiatry
pub_type: 杂志文章,评审
doi:10.3389/fpsyt.2019.00098
更新日期:2019-03-01 00:00:00
abstract::Background: Inpatient mental health wards are reported by many consumers to be custodial, unsafe, and lacking in therapeutic relationships. These consumer experiences are concerning, given international policy directives requiring recovery-oriented practice. Safewards is both a model and a suite of interventions desig...
journal_title:Frontiers in psychiatry
pub_type: 杂志文章
doi:10.3389/fpsyt.2019.00461
更新日期:2019-07-09 00:00:00
abstract::The prevalence of alcohol abuse among patients treated in accident and emergency departments (A&E) is considered as substantial. This paper is a narrative review of studies investigating the effectiveness of brief interventions (BI) for hazardous and harmful alcohol consumption in A&E. A&E departments in hospitals (an...
journal_title:Frontiers in psychiatry
pub_type: 杂志文章,评审
doi:10.3389/fpsyt.2014.00152
更新日期:2014-11-03 00:00:00
abstract::Background: In Germany, people suffering from severe mental illness who have committed serious offenses and have considerably reduced or suspended criminal responsibility can be detained and treated in forensic psychiatric hospitals. In the German federal state of Baden-Wuerttemberg, all psychiatric hospitals includin...
journal_title:Frontiers in psychiatry
pub_type: 杂志文章
doi:10.3389/fpsyt.2020.00146
更新日期:2020-03-05 00:00:00
abstract::This paper focuses on depression that precedes an onset of manifest bipolar disorder as early stage bipolar disorder. First, we review how to pragmatically identify the clinical characteristics of patients presenting with an episode of depression who subsequently go on to develop episodes of mania or hypomania. The ex...
journal_title:Frontiers in psychiatry
pub_type: 杂志文章,评审
doi:10.3389/fpsyt.2020.00500
更新日期:2020-06-11 00:00:00
abstract::Tourette syndrome (TS) is a developmental neuropsychiatric disorder with onset during childhood. Because of its complex spectrum of phenotypes, the underlying pathophysiology of TS is still unclear. Resting-state functional magnetic resonance imaging demonstrated aberrant spontaneous neural synchronization in conventi...
journal_title:Frontiers in psychiatry
pub_type: 杂志文章
doi:10.3389/fpsyt.2020.543049
更新日期:2020-12-17 00:00:00
abstract:Background:In the Corona Virus Disease 2019 (COVID-19) pandemic, the primary problem is respiratory-related, but there also is increasing evidence of central nervous system (CNS) involvement. This study aims to summarize the literature on neurological manifestations of COVID-19, underlying mechanisms of CNS involvement...
journal_title:Frontiers in psychiatry
pub_type: 杂志文章,评审
doi:10.3389/fpsyt.2020.00860
更新日期:2020-08-21 00:00:00
abstract::Neuroimaging holds the promise that it may one day aid the clinical assessment of individual psychiatric patients. However, the vast majority of studies published so far have been based on average differences between groups, which do not permit accurate inferences at the level of the individual. We examined the potent...
journal_title:Frontiers in psychiatry
pub_type: 杂志文章
doi:10.3389/fpsyt.2013.00187
更新日期:2014-01-29 00:00:00
abstract:Background:Mobile phone addiction behaviors (MPAB) are extensively associated with several mental and sleep problems. Only a limited number of bidirectional longitudinal papers have focused on this field. This study aimed to examine the bidirectional associations of MPAB with mental distress, sleep disturbances, and sl...
journal_title:Frontiers in psychiatry
pub_type: 杂志文章
doi:10.3389/fpsyt.2020.00634
更新日期:2020-07-17 00:00:00
abstract::The aim of this study is to explore the changes and clinical significance of serum C3, C4, hypersensitive C-reactive protein (hsCRP) and uric acid (UA) in patients of bipolar disorder (BD). In this case-control study, we recruited 141 BD patients from The Second Xiangya Hospital, Central South University, and 151 age ...
journal_title:Frontiers in psychiatry
pub_type: 杂志文章
doi:10.3389/fpsyt.2018.00381
更新日期:2018-08-21 00:00:00
abstract:Introduction:Psychosocial stressors may worsen psychotic symptoms in schizophrenia, while social support could protect against the effects of stress in schizophrenia. Hypothalamus-pituitary-adrenal axis dysfunction has been associated with schizophrenia. Hair cortisol concentrations (HCC) allow assessment of cumulative...
journal_title:Frontiers in psychiatry
pub_type: 杂志文章
doi:10.3389/fpsyt.2020.572656
更新日期:2020-09-24 00:00:00
abstract::Background: Left-behind children (LBC) are becoming a widespread phenomenon and face higher risks of psychological and educational problems. Our study aimed to explore school bullying in LBC and examine the effectiveness of art therapy intervention for reducing bullying victimization affecting LBC in rural areas. Meth...
journal_title:Frontiers in psychiatry
pub_type: 杂志文章
doi:10.3389/fpsyt.2019.00040
更新日期:2019-02-07 00:00:00
abstract::Employment rate in psychiatry is around 10 to 30%. Cognitive remediation (CR) associated with psychosocial rehabilitation shows good functional outcomes, with a high level of satisfaction in participants provided by tailored CR. However, few studies looked at the long-term outcome in participants who experienced such ...
journal_title:Frontiers in psychiatry
pub_type: 杂志文章
doi:10.3389/fpsyt.2020.00609
更新日期:2020-07-03 00:00:00
abstract::Voxel-based morphometry (VBM) is a commonly used method to study volumetric variations on a whole brain basis. However, it is often criticized for potential confounds, mainly based on imperfect spatial registration. We therefore aimed to evaluate if VBM and "gold standard" manual volumetry are measuring the same effec...
journal_title:Frontiers in psychiatry
pub_type: 杂志文章
doi:10.3389/fpsyt.2014.00039
更新日期:2014-04-08 00:00:00
abstract::Background: The burden of mental, neurological, and substance (MNS) disorders is greater in low- and middle-income countries (LMICs). The rapid growth of digital health (i.e., eHealth) approaches offer new solutions for transforming pediatric mental health services and have the potential to address multiple resource a...
journal_title:Frontiers in psychiatry
pub_type:
doi:10.3389/fpsyt.2019.00806
更新日期:2019-11-13 00:00:00
abstract::Introduction: Previous studies have indicated that changes in the concentration of glutamate and related metabolites may mediate the progression of addiction in patients with methamphetamine (MA) use disorders. In the present study, we utilized magnetic resonance spectroscopy (MRS) to investigate absolute glutamate co...
journal_title:Frontiers in psychiatry
pub_type: 杂志文章
doi:10.3389/fpsyt.2018.00368
更新日期:2018-08-31 00:00:00
abstract::Background: Individuals with severe mental disorder (SMD) have a higher risk of somatic comorbidity and mortality than the rest of the population. We set up a population-based study to assess whether individuals with SMD had a higher risk of death associated with a COVID-19 infection (COVID-19 associated death) than i...
journal_title:Frontiers in psychiatry
pub_type: 杂志文章
doi:10.3389/fpsyt.2020.609579
更新日期:2021-01-08 00:00:00
abstract::In a group of 1066 heroin addicts, who were seeking treatment for opioid agonist treatment, we looked for differences in historical, demographic, and clinical characteristics, between patients with different levels of awareness of illness (insight). The results showed that, in the cohort studied, a majority of subject...
journal_title:Frontiers in psychiatry
pub_type: 杂志文章
doi:10.3389/fpsyt.2012.00061
更新日期:2012-07-09 00:00:00
abstract::Suicide is a serious public health issue worldwide, yet current clinical methods for assessing a person's risk of taking their own life remain unreliable and new methods for assessing suicide risk are being explored. The widespread adoption of electronic health records (EHRs) has opened up new possibilities for epidem...
journal_title:Frontiers in psychiatry
pub_type: 杂志文章,评审
doi:10.3389/fpsyt.2020.553463
更新日期:2020-11-27 00:00:00