Reversible hypothyroidism and Whipple's disease.

abstract：BACKGROUND:The burden of non-communicable diseases is growing rapidly in low- and middle-income countries. Research suggests that health interventions that aim to improve patient self-management and empower patients to care actively for their disease will improve health outcomes over the long-term. There is, however, a...

journal_title：BMC endocrine disorders

authors： Abrahams N,Gilson L,Levitt NS,Dave JA

更新日期：2019-12-05 00:00:00

abstract：BACKGROUND:Caloric restriction is an effective way to treat Type 2 diabetes (T2D). However, chronic and severe restriction of food intake is difficult to sustain and is known to promote slower metabolism. Intermittent and frequent fasting can exert similar metabolic effects, but may be even more challenging for most pa...

journal_title：BMC endocrine disorders

authors： van den Burg EL,Schoonakker MP,van Peet PG,van den Akker-van Marle ME,Willems van Dijk K,Longo VD,Lamb HJ,Numans ME,Pijl H

更新日期：2020-06-24 00:00:00

abstract：BACKGROUND:The prevalence of type 2 diabetes mellitus (T2DM) is expected to increase from 7.7% in 2017 to 8.4% in 2045 worldwide. Diabetes complications contribute to morbidity and mortality. To evaluate whether the diabetes complications severity index (DCSI) was associated with increased risks of mortality and hospit...

journal_title：BMC endocrine disorders

authors： Yoo H,Choo E,Lee S

更新日期：2020-08-10 00:00:00

abstract：BACKGROUND:Insufficient vitamin D status and increased renin-angiotensin system (RAS) activity have been associated with renal-vascular disease and nephropathy in diabetes. Accumulating evidence indicates that vitamin D receptor (VDR) activation lowers unfavorable RAS activity; however, more human intervention studies ...

journal_title：BMC endocrine disorders

authors： Brown JM,Secinaro K,Williams JS,Vaidya A

更新日期：2013-08-23 00:00:00

abstract：BACKGROUND:Previous studies have shown the negative impact of sleep disturbances, specifically insomnia symptoms, on glucose metabolism for people with type 2 diabetes (T2D). People with insomnia symptoms are at risk of poor glycemic control and suboptimal diabetes self-care behavior (DSCB). Investigating the impact of...

journal_title：BMC endocrine disorders

authors： Alshehri MM,Alothman SA,Alenazi AM,Rucker JL,Phadnis MA,Miles JM,Siengsukon CF,Kluding PM

更新日期：2020-09-05 00:00:00

abstract：BACKGROUND:In primary health care systems where member's turnover is relatively low, the question, whether investment in quality of care improvement can make a business case, or is cost effective, has not been fully answered.The objectives of this study were: (1) to investigate the relationship between improvement in s...

journal_title：BMC endocrine disorders

authors： Wilf-Miron R,Bolotin A,Gordon N,Porath A,Peled R

更新日期：2014-12-01 00:00:00

abstract：BACKGROUND:Limited real-world data are currently available on hypoglycemia in diabetes patients. The International Operations Hypoglycemia Assessment Tool (IO HAT) study was designed to estimate hypoglycemia in insulin-treated type I (T1DM) and type II (T2DM) diabetes mellitus patients from 9 countries. The data from T...

journal_title：BMC endocrine disorders

authors： Emral R,Tetiker T,Sahin I,Sari R,Kaya A,Yetkin İ,Cil SU,Tütüncü NB,IO HAT investigator group.

更新日期：2018-02-13 00:00:00

abstract：BACKGROUND:A growing body of evidence supports neutrophils as having an active role in the development of diabetic kidney disease (DKD). However, the clinical relevance of neutrophils and DKD in autoimmune diabetes remains unknown. This study aimed to investigate the relationship between circulating neutrophils and DKD...

journal_title：BMC endocrine disorders

authors： Yu Y,Lin Q,Ye D,Wang Y,He B,Li Y,Huang G,Zhou Z,Xiao Y

更新日期：2020-10-22 00:00:00

abstract：BACKGROUND:Hyperglycemia induces chromatin remodeling with consequences on differential gene expression in mouse hepatocytes, similar to what occurs during aging. The liver is the central organ for the regulation of glucose homeostasis and xenobiotic and lipid metabolism and is affected by insulin signaling. The precis...

journal_title：BMC endocrine disorders

authors： Ghiraldini FG,Silveira AB,Kleinjan DA,Gilbert N,Mello ML

更新日期：2014-03-03 00:00:00

abstract：BACKGROUND:While poor sleep quality can worsen cardiovascular risk factors such as glucose and lipid profiles in patients with type 2 diabetes mellitus (T2DM), the relationship between sleep quality and atherosclerosis remains largely unknown. The aim of this study was to examine this relationship. METHODS:The study p...

journal_title：BMC endocrine disorders

authors： Osonoi Y,Mita T,Osonoi T,Saito M,Tamasawa A,Nakayama S,Someya Y,Ishida H,Kanazawa A,Gosho M,Fujitani Y,Watada H

更新日期：2015-06-18 00:00:00

abstract：BACKGROUND:The objective was to examine how the indigenous naming, indigenous self-diagnosis and management of diabetes evolved with awareness in order to develop a socially oriented theoretical model for its care. METHODS:The data was collected through a one-year extended participant observation in Bafut, a rural hea...

journal_title：BMC endocrine disorders

authors： Awah PK,Unwin NC,Phillimore PR

更新日期：2009-02-19 00:00:00

abstract：AIM:To assess the factors associated with antihyperglycaemic medication initiation in UK patients with newly diagnosed type 2 diabetes. METHODS:In a retrospective cohort study, patients with newly diagnosed type 2 diabetes were identified during the index period of 2003-2005. Eligible patients were ≥ 30 years old at t...

journal_title：BMC endocrine disorders

authors： Sinclair AJ,Alexander CM,Davies MJ,Zhao C,Mavros P

更新日期：2012-03-07 00:00:00

abstract：BACKGROUND:Parathyroid carcinoma is a rare neoplasm that may present sporadically or in the context of a genetic syndrome. Diagnosis and management are challenging due to the lack of clinical and pathological features that may reliably distinguish malignant from benign disease. METHODS:From January 2013 to December 20...

journal_title：BMC endocrine disorders

authors： Ferraro V,Sgaramella LI,Di Meo G,Prete FP,Logoluso F,Minerva F,Noviello M,Renzulli G,Gurrado A,Testini M

更新日期：2019-05-29 00:00:00

abstract：BACKGROUND:Diabetes mellitus (DM) leads to multiple complications, including severe hypoglycaemia events (SHEs). SHEs can impact a patient's quality of life and compliance and may directly result in additional costs to the health care system. The aim of this review was to evaluate the risk of severe hypoglycaemia in pa...

journal_title：BMC endocrine disorders

authors： Czech M,Rdzanek E,Pawęska J,Adamowicz-Sidor O,Niewada M,Jakubczyk M

更新日期：2015-10-12 00:00:00

abstract：BACKGROUND:Hypoparathyroidism, deafness, and renal dysplasia (HDR) syndrome is a rare autosomal dominant disorder caused by mutations in the zinc finger transcription factor gene, GATA3. GATA3 has 2 zinc finger domains, which play an important role in the increase in target gene transcription activity. CASE PRESENTATI...

journal_title：BMC endocrine disorders

authors： Okawa T,Yoshida M,Usui T,Kudou T,Iwasaki Y,Fukuoka K,Takahashi N,Uehara Y,Oiso Y

更新日期：2015-10-30 00:00:00

abstract：UNLABELLED: BACKGROUND:Severe hypoglycaemia (SH) is one of the most feared complications of type 1 diabetes (T1DM) with a reported prevalence of nearly 40%. In randomized trials of Multiple Daily Injections (MDI) and Continuous Subcutaneous Insulin Infusion (CSII) therapy there is a possible benefit of CSII in reducin...

journal_title：BMC endocrine disorders

authors： Little S,Chadwick T,Choudhary P,Brennand C,Stickland J,Barendse S,Olateju T,Leelarathna L,Walkinshaw E,Tan HK,Marshall SM,Thomas RM,Heller S,Evans M,Kerr D,Flanagan D,Speight J,Shaw JA

更新日期：2012-12-13 00:00:00

abstract：BACKGROUND:Medullary thyroid carcinoma is a malignant uncommon and aggressive tumour of the parafollicular C cells. In about 75% of cases it is sporadic while, in case of RET mutation, it is associated to multiple endocrine neoplasia type 2 (25% of cases). The biochemical features of medullary thyroid carcinoma include...

journal_title：BMC endocrine disorders

authors： Gambardella C,Offi C,Clarizia G,Romano RM,Cozzolino I,Montella M,Di Crescenzo RM,Mascolo M,Cangiano A,Di Martino S,Candela G,Docimo G

更新日期：2019-10-16 00:00:00

abstract：BACKGROUND:Type 2 diabetic patients display significantly higher incidence of cardiovascular (CV) events including stroke compared to non-diabetics. Morning blood pressure surge (MBPS) and blunted systolic night-day (SND) ratio have been associated with CV events in hypertensive patients. No studies have evaluated MBPS...

journal_title：BMC endocrine disorders

authors： Lyhne JM,Laugesen E,Høyem P,Cichosz S,Christiansen JS,Knudsen ST,Hansen KW,Hansen TK,Poulsen PL

更新日期：2015-12-03 00:00:00

abstract：BACKGROUND:This study tested the association between serum levels of microRNA-486, -146b and -15b and betatrophin in normal and obese children with/without type 2 diabetes mellitus (T2DM). METHODS:the study included 120 children; divided into three groups: G1 (50 healthy), G2 (35 obese) and G3 (35 obese with T2DM). Th...

journal_title：BMC endocrine disorders

authors： Mohany KM,Al Rugaie O,Al-Wutayd O,Al-Nafeesah A,Saleem TH

更新日期：2020-09-29 00:00:00

abstract：:BACKGROUND: The possible participation of endogenous islet catecholamines (CAs) in the control of insulin secretion was tested. METHODS: Glucose-induced insulin secretion was measured in the presence of 3-Iodo-L-Tyrosine (MIT), a specific inhibitor of tyrosine-hydroxylase activity, in fresh and precultured islets isol...

journal_title：BMC endocrine disorders

authors： Borelli MI,Gagliardino JJ

更新日期：2001-01-01 00:00:00

abstract：UNLABELLED: BACKGROUND:Hypoglycaemia is a serious adverse effect of antidiabetic drug therapy. We aimed to determine incidence rates of hypoglycaemia in type-2 diabetic patients and identify predictors of hypoglycaemia when treatment is intensified. METHODS:DiaRegis is a prospective German registry that follows 3810 ...

journal_title：BMC endocrine disorders

authors： Tschöpe D,Bramlage P,Binz C,Krekler M,Deeg E,Gitt AK

更新日期：2012-10-17 00:00:00

abstract：BACKGROUND:Adipose tissue abundance relies partly on the factors that regulate adipogenesis, i.e. proliferation and differentiation of adipocytes. While components of the transcriptional program that initiates adipogenesis is well-known, the importance of microRNAs in adipogenesis is less well studied. We thus set out ...

journal_title：BMC endocrine disorders

authors： Keller P,Gburcik V,Petrovic N,Gallagher IJ,Nedergaard J,Cannon B,Timmons JA

更新日期：2011-03-22 00:00:00

abstract：BACKGROUND:Diabetes is a major public health problem worldwide. This problem is particularly relevant to the elderly. The prevalence of each condition increase with age. The present study aimed to determine the prevalence of Diabetes Mellitus (DM) among elderly; we also examined socio-economic factors and life style th...

journal_title：BMC endocrine disorders

authors： Hammami S,Mehri S,Hajem S,Koubaa N,Souid H,Hammami M

更新日期：2012-08-16 00:00:00

abstract：BACKGROUND:This study aimed to measure the effect of diabetes education using the novel method of "diabetes conversation map (DCM)" as compared to routine counselling (RC) on diabetes management self-efficacy (DMSE) among patients living with type 2 diabetes in Karachi, Pakistan. METHODS:A parallel arm randomized cont...

journal_title：BMC endocrine disorders

authors： Qasim R,Masih S,Yousafzai MT,Shah H,Manan A,Shah Y,Yaqoob M,Razzaq A,Khan A,Rohilla ARK

更新日期：2020-06-16 00:00:00

abstract：BACKGROUND:Chronic insulin resistance, exacerbated in the course of pregnancy, is an important pathophysiologic mechanism of gestational diabetes mellitus (GDM). We hypothesise that the degree of insulin resistance, assessed at diagnosis of GDM, is a parameter of its pathophysiologic heterogeneity and/or severity. Thus...

journal_title：BMC endocrine disorders

authors： Sokup A,Ruszkowska-Ciastek B,Góralczyk K,Walentowicz M,Szymański M,Rość D

更新日期：2013-07-02 00:00:00

abstract：BACKGROUND:Addison's disease, or primary adrenal insufficiency, is often associated with reduced well-being and fatigue despite use of currently recommended adrenal hormone replacement. Hypoglycaemia is a known manifestation of glucocorticoid deficiency, but is generally considered rare in adults and not relevant to tr...

journal_title：BMC endocrine disorders

authors： Petersen KS,Rushworth RL,Clifton PM,Torpy DJ

更新日期：2015-10-24 00:00:00

abstract：BACKGROUND:The purpose of this study was to evaluate the association between blood manganese levels and the prevalence of chronic diseases in the Korean population. METHODS:This was a cross-sectional study based on the Korean National Health and Nutrition Examination Survey (KNAHNES). The study included 3996 participa...

journal_title：BMC endocrine disorders

authors： Koh ES,Kim SJ,Yoon HE,Chung JH,Chung S,Park CW,Chang YS,Shin SJ

更新日期：2014-03-08 00:00:00

abstract：BACKGROUND:The discovery of sodium-glucose co-transporter 2 (SGLT2) inhibitors, with a novel mechanism independent of insulin secretion or sensitization, bring about a new therapeutic approach to the management of type 2 diabetes mellitus. The aim of this meta-analysis was to evaluate the safety and efficacy of SGLT2 i...

journal_title：BMC endocrine disorders

authors： Berhan A,Barker A

更新日期：2013-12-17 00:00:00

abstract：BACKGROUND:There have only been a few reports about use of dipeptidyl peptidase 4 (DPP-4) inhibitors in elderly patients with type 2 diabetes mellitus (T2DM), suggesting that the safety of these agents has not been sufficiently demonstrated. We performed a comparative review of the efficacy and safety of sitagliptin fo...

journal_title：BMC endocrine disorders

authors： Umezawa S,Kubota A,Maeda H,Kanamori A,Matoba K,Jin Y,Minagawa F,Obana M,Iemitsu K,Ito S,Amamiya H,Kaneshiro M,Takai M,Kaneshige H,Hoshino K,Ishikawa M,Minami N,Takuma T,Sasai N,Aoyagi S,Kawata T,Mokubo A,Miyai

更新日期：2015-07-03 00:00:00

abstract：BACKGROUND:Acromegaly is highly associated with thyroid disorders. However, the clinical characteristics of thyroid nodules in individuals with acromegaly who present with thyroid diseases have not been completely elucidated. METHODS:Overall, 134 consecutive participants with growth hormone (GH)-secreting adenoma (n =...

journal_title：BMC endocrine disorders

authors： Xu D,Wu B,Li X,Cheng Y,Chen D,Fang Y,Du Q,Chen Z,Wang X

更新日期：2019-09-02 00:00:00