Nondrug-related aspect of treating Ekbom disease, formerly known as restless legs syndrome.

abstract：:Dopaminergic agents, anticonvulsants, benzodiazepines, opiates, and iron supplementation comprise the classes of medications commonly used to treat restless legs syndrome (RLS), which is a disorder that is estimated to affect about 1 in 10 individuals worldwide and impacts an affected patient's sleep, mood, daytime fu...

journal_title：Neuropsychiatric disease and treatment

authors： Kushida CA

更新日期：2006-12-01 00:00:00

abstract：:The neurodevelopmental hypothesis of schizophrenia posits that schizophrenia is a psychopathological condition resulting from aberrations in neurodevelopmental processes caused by a combination of environmental and genetic factors which proceed long before the onset of clinical symptoms. Many studies discuss an immuno...

journal_title：Neuropsychiatric disease and treatment

authors： Mattei D,Schweibold R,Wolf SA

更新日期：2015-05-27 00:00:00

abstract：:Up to 20% of depressed patients demonstrate treatment resistance to one or more adequate antidepressant trials, resulting in a disproportionately high burden of illness. Ketamine is a non-barbiturate, rapid-acting general anesthetic that has been increasingly studied in treatment resistant depression (TRD), typically ...

journal_title：Neuropsychiatric disease and treatment

authors： Jankauskas V,Necyk C,Chue J,Chue P

更新日期：2018-06-06 00:00:00

abstract：Purpose:Entropy analysis of resting-state functional magnetic resonance imaging (R-fMRI) has recently been adopted to characterize brain temporal dynamics in some neuropsychological or psychiatric diseases. Thalamus-related dysfunction might be a potential trait marker of major depressive disorder (MDD), but the abnorm...

journal_title：Neuropsychiatric disease and treatment

authors： Xue SW,Wang D,Tan Z,Wang Y,Lian Z,Sun Y,Hu X,Wang X,Zhou X

更新日期：2019-09-11 00:00:00

abstract：:Some of trauma-exposed individuals develop posttraumatic stress disorder (PTSD), an incapacitating psychiatric disorder that is characterized by intrusion, avoidance, negative changes in mood and cognition, and hyperarousal. A number of other trauma-related conditions are very frequently found in individuals with PTSD...

journal_title：Neuropsychiatric disease and treatment

authors： Namgung E,Kim M,Yoon S

更新日期：2019-03-19 00:00:00

abstract：Purpose:Stroke remains the primary cause of pain, suffering, and death in patients. One of the major thrusts in stroke therapy is to find an effective prevention strategy. Objectives of this study are to testify the neuro-protection effect of stigmasterol in ischemic/reperfusion injury model. Methods:The dosage-depend...

journal_title：Neuropsychiatric disease and treatment

authors： Sun J,Li X,Liu J,Pan X,Zhao Q

更新日期：2019-10-18 00:00:00

abstract：:Delirium occurs in 23% of sepsis patients, in which pro-inflammatory cytokines and nitric oxide are suggested to be involved. However, in animal experiments, even a subseptic dose of lipopolysaccharide (LPS) injection induces both pro-inflammatory cytokines and inducible nitric oxide synthase in the brain, suggesting ...

journal_title：Neuropsychiatric disease and treatment

authors： Maeda S,Nakatsuka I,Hayashi Y,Higuchi H,Shimada M,Miyawaki T

更新日期：2008-06-01 00:00:00

abstract：:Stem cells are self-renewing undifferentiated cells that give rise to multiple types of specialized cells of the body. In the adult, stem cells are multipotents and contribute to homeostasis of the tissues and regeneration after injury. Until recently, it was believed that the adult brain was devoid of stem cells, hen...

journal_title：Neuropsychiatric disease and treatment

authors： Taupin P

更新日期：2007-12-01 00:00:00

abstract：Background:Various personality traits mediate the association between childhood stress and depressive symptoms in adulthood. The aim of this study was to clarify the indirect effects of the experience of child maltreatment on depressive symptoms and appraisal of life events in adulthood through trait anxiety. Subjects...

journal_title：Neuropsychiatric disease and treatment

authors： Uchida Y,Takahashi T,Katayama S,Masuya J,Ichiki M,Tanabe H,Kusumi I,Inoue T

更新日期：2018-11-27 00:00:00

abstract：:Antipsychotics are the mainstay in schizophrenia management, and long-acting injectable (LAI) antipsychotics contribute to the successful maintenance of treatment by improving non-adherence and preventing relapses. Paliperidone palmitate 3-monthly (PP3M) formulation is the only available LAI antipsychotic that offers ...

journal_title：Neuropsychiatric disease and treatment

authors： Mathews M,Gopal S,Nuamah I,Hargarter L,Savitz AJ,Kim E,Tan W,Soares B,Correll CU

更新日期：2019-05-21 00:00:00

abstract：BACKGROUND:Stroke has high mortality and morbidity. Biomarkers are required for to predict stroke outcomes, which could help clinicians to provide rationale approaches for patient management. The dynamic changes in circulating immune cells have been reported in stroke patients and animal models of stroke. AIM:The aim ...

journal_title：Neuropsychiatric disease and treatment

authors： Wang Y,Liu J,Wang X,Liu Z,Li F,Chen F,Geng X,Ji Z,Du H,Hu X

更新日期：2017-10-03 00:00:00

abstract：:Diagnosis of complex partial epilepsy is based on the clinical history, and laboratory tests, including EEG and neuroimaging studies, corroborate the diagnosis. The goal of epilepsy management is to make the patient completely seizure-free without drug-induced side effects, even in the patient with refractory complex ...

journal_title：Neuropsychiatric disease and treatment

authors： Treiman DM

更新日期：2010-06-24 00:00:00

abstract：Background:Post-stroke depression (PSD) is one of the most common psychiatric diseases afflicting stroke survivors. This study was conducted to assess the efficacy of ginkgo biloba extract as augmentation of venlafaxine in treating PSD. Methods:The included PSD patients were randomly assigned into the experiment group...

journal_title：Neuropsychiatric disease and treatment

authors： Liang ZH,Jia YB,Wang ML,Li ZR,Li M,Yun YL,Zhu RX

更新日期：2019-09-03 00:00:00

abstract：BACKGROUND:Anhedonia constitutes a coherent construct, with neural correlates and negative clinical impact, independent of depression. However, little is known about the neural correlates of anhedonia in stroke patients. In this study, we investigated the association of post-stroke anhedonia with salivary cortisol leve...

journal_title：Neuropsychiatric disease and treatment

authors： Terroni L,Amaro E Jr,Iosifescu DV,Mattos P,Yamamoto FI,Tinone G,Conforto AB,Sobreiro MF,Guajardo VD,De Lucia MC,Moreira AC,Scaff M,Leite CC,Fraguas R

更新日期：2015-02-03 00:00:00

abstract：PURPOSE:To investigate the perception of dignity among patients hospitalized in a psychiatric setting using the Patient Dignity Inventory (PDI), which had been first validated in oncologic field among terminally ill patients. PATIENTS AND METHODS:After having modified two items, we administered the Italian version of ...

journal_title：Neuropsychiatric disease and treatment

authors： Di Lorenzo R,Cabri G,Carretti E,Galli G,Giambalvo N,Rioli G,Saraceni S,Spiga G,Del Giovane C,Ferri P

更新日期：2017-01-23 00:00:00

abstract：:Neuropsychiatric symptoms are common in older adults with dementia and can be associated with a rapid decline in cognitive and functional status. This article reviews the current literature supporting the use of atypical antipsychotic medications in this population. Among the currently available atypical antipsychotic...

journal_title：Neuropsychiatric disease and treatment

authors： Lee PE,Gill SS,Rochon P

更新日期：2006-12-01 00:00:00

abstract：Background:Mental disorders affect about one-third of the human population, are typically chronic and significantly decrease the quality of life. Presently, the treatment of mental illnesses is far from adequate with a substantial proportion of the patients being pharmacoresistant and suffering from relapses. One of t...

journal_title：Neuropsychiatric disease and treatment

authors： Latalova K,Sery O,Hosakova K,Hosak L

更新日期：2020-05-06 00:00:00

abstract：:Studies that have carried out experimental evaluation of emotional skills in alcohol-dependence have, up to now, been mainly focused on the exploration of emotional facial expressions (EFE) decoding. In the present paper, we provide some complements to the recent systematic literature review published by Donadon and d...

journal_title：Neuropsychiatric disease and treatment

authors： D'Hondt F,Campanella S,Kornreich C,Philippot P,Maurage P

更新日期：2014-11-18 00:00:00

abstract：:Co-morbid depression is common in patients with diabetes mellitus and has a negative impact on diabetes self-care, adherence to treatment and the development of complications. Effective treatment of depression has been associated with improvement in metabolic parameters. We evaluated the feasibility of a two question ...

journal_title：Neuropsychiatric disease and treatment

authors： Abrahamian H,Hofmann P,Prager R,Toplak H

更新日期：2009-01-01 00:00:00

abstract：BACKGROUND:In the current Japanese payment system for the treatment of psychiatric inpatients, the length of hospital stay and nurse staffing levels are key determinants of the amount of payment. These factors do not fully reflect the costs of care for each patient. The objective of this study was to clarify the relati...

journal_title：Neuropsychiatric disease and treatment

authors： Sugibayashi Y,Yoshimura K,Yamauchi K,Inagaki A,Ikegami N

更新日期：2014-08-25 00:00:00

abstract：:Traumatic brain injury (TBI) is a well recognized public health problem worldwide. TBI has previously been considered as a rare cause of hypopituitarism, but an increased prevalence of neuroendocrine dysfunction in patients with TBI has been reported during the last 15 years in most of the retrospective and prospectiv...

journal_title：Neuropsychiatric disease and treatment

authors： Tanriverdi F,Kelestimur F

更新日期：2015-07-27 00:00:00

abstract：:The cerebral cortex of the human brain has a complex morphological structure consisting of folded or smooth cortical surfaces. These morphological features are referred to as cortical gyrification and are characterized by the gyrification index (GI). A number of cortical gyrification studies have been published using ...

journal_title：Neuropsychiatric disease and treatment

authors： Matsuda Y,Ohi K

更新日期：2018-07-19 00:00:00

abstract：Background:The phospholipase A2 Group 6 (PLA2G6, also known as PLA2, PARK14, and iPLA2) gene encodes a group VIA calcium-independent phospholipase A2. Genetic polymorphism of PLA2G6 has been indicated to be involved in conferring susceptibility for Parkinson's disease (PD), whereas conclusive results have not been obta...

journal_title：Neuropsychiatric disease and treatment

authors： Liu H,Yao Y,Liu H,Peng Y,Ren J,Wu X,Mao R,Zhao J,Zhu Y,Niu Z,Yang T,Sun X,Jiang P,Zhang C,Fang Y

更新日期：2020-07-23 00:00:00

abstract：OBJECTIVE:Cognitive theory assumes a pivotal role of negative core beliefs about the self in dysfunctional attitudes predisposing to depression. Meanwhile, the role of positive core beliefs about the self in cognitive vulnerability to depression is unknown. Therefore, we examined the relationship of negative and positi...

journal_title：Neuropsychiatric disease and treatment

authors： Otani K,Suzuki A,Matsumoto Y,Shirata T

更新日期：2017-10-12 00:00:00

abstract：Introduction:The study was designed to explore the possible adverse effects of prenatal polycyclic aromatic hydrocarbons (PAHs) on the neurodevelopment of the infants at the age of 12 months in a birth cohort in Qingdao of China. Benzo[a]pyrene (BaP)-DNA adduct level in umbilical cord blood was measured by enzyme immun...

journal_title：Neuropsychiatric disease and treatment

authors： Zhang Y,Yang Y,Zhang Q,Cui J,Rahaman A,Huang XR,Su Y,Gao R,Wang B,Baloch Z

更新日期：2019-12-02 00:00:00

abstract：Objective:This study compared the effect of levetiracetam (LEV) as monotherapy to sodium valproate (VPA) as monotherapy on cognitive functions in patients with epilepsy. Methods:This was a comparative prospective study on 50 patients with newly diagnosed epilepsy started on antiseizure medications. Patients were selec...

journal_title：Neuropsychiatric disease and treatment

authors： El Sabaa RM,Hamdi E,Hamdy NA,Sarhan HA

更新日期：2020-08-11 00:00:00

abstract：:Bipolar disorder (BD) is a debilitating and difficult-to-treat psychiatric disease that presents a serious burden to patients' lives as well as health care systems around the world. The essential diagnostic criterion for BD is episodes of mania or hypomania; however, the patients report that the majority of their time...

journal_title：Neuropsychiatric disease and treatment

authors： Franklin R,Zorowitz S,Corse AK,Widge AS,Deckersbach T

更新日期：2015-08-19 00:00:00

abstract：:We report a case in which selegiline, an irreversible monoamine oxidase B (MAO-B) inhibitor, greatly improved depressive symptoms in an adult with stage 5 treatment-resistant major depressive disorder. Four antidepressants and four augmentation therapies had previously been ineffective or intolerable, and electroconvu...

journal_title：Neuropsychiatric disease and treatment

authors： Kitaichi Y,Inoue T,Mitsui N,Nakagawa S,Kameyama R,Hayashishita Y,Shiga T,Kusumi I,Koyama T

更新日期：2013-01-01 00:00:00

abstract：Purpose:Dual diagnosis (DD) is the co-occurrence of both a mental illness and a substance use disorder (SUD). Lots of studies have analysed the integrated clinical approach, which involves both psychiatry and toxicology medical experts. The purpose of this study is to analyse the socio-demographic characteristics and t...

journal_title：Neuropsychiatric disease and treatment

authors： Milano G,Vergani HM,Cattedra S,Carrozzino R,Mattioli F,Robbiano L,Martelli A

更新日期：2019-12-18 00:00:00

abstract：:In the present study, we investigated the relationship between physical activity (PA) and self-esteem (SE), while introducing body mass index (BMI), perceived physical fitness (PPF), and body image (BI) in adults (N =264, M =38.10 years). The findings indicated that PA was directly and indirectly associated with SE. B...

journal_title：Neuropsychiatric disease and treatment

authors： Zamani Sani SH,Fathirezaie Z,Brand S,Pühse U,Holsboer-Trachsler E,Gerber M,Talepasand S

更新日期：2016-10-12 00:00:00