Selegiline remarkably improved stage 5 treatment-resistant major depressive disorder: a case report.

abstract：:The cerebral cortex of the human brain has a complex morphological structure consisting of folded or smooth cortical surfaces. These morphological features are referred to as cortical gyrification and are characterized by the gyrification index (GI). A number of cortical gyrification studies have been published using ...

journal_title：Neuropsychiatric disease and treatment

authors： Matsuda Y,Ohi K

更新日期：2018-07-19 00:00:00

abstract：BACKGROUND:Deltamethrin (DLM) is a broad-spectrum synthetic dibromo-pyrethroid pesticide that is widely used for agricultural and veterinary purposes. However, human exposure to the pesticide leads to neurotoxicity. Glutamine is one of the principal, free intracellular amino acids and may also be an antioxidant. This s...

journal_title：Neuropsychiatric disease and treatment

authors： Varol S,Özdemir HH,Çevik MU,Altun Y,Ibiloğlu I,Ekinci A,Ibiloğlu AO,Balduz M,Arslan D,Tekin R,Aktar F,Aluçlu MU

更新日期：2016-04-21 00:00:00

abstract：BACKGROUND:Metabolic syndrome (MetS) is one of the primary reasons for increased mortality in patients with schizophrenia. The mechanisms involved in its pathogenesis are not well understood. OBJECTIVE:To estimate the prevalence of MetS in adult outpatients with schizophrenia according to the presence or absence of ne...

journal_title：Neuropsychiatric disease and treatment

authors： Sicras-Mainar A,Maurino J,Ruiz-Beato E,Navarro-Artieda R

更新日期：2014-12-30 00:00:00

abstract：Purpose:To investigate the current clinical practice of Japanese physicians in the diagnosis and management of major depression (major depressive disorder [MDD]). Patients and methods:Japanese physicians specializing in psychiatry or psychosomatic medicine in the medical database of Nihon Ultmarc Inc. (Chuo-Ku, Tokyo,...

journal_title：Neuropsychiatric disease and treatment

authors： Hori H,Yamato K

更新日期：2019-10-01 00:00:00

abstract：:Psychiatric and physical conditions often coexist, and there is robust evidence that associates the frequency of depression with single and multiple physical conditions. More than half of patients with depression may have at least one chronic physical condition. Therefore, antidepressants are often used in cotherapy w...

journal_title：Neuropsychiatric disease and treatment

authors： Low Y,Setia S,Lima G

更新日期：2018-02-19 00:00:00

abstract：Background:Impulsivity is one of the principal symptoms of bipolar and related disorders (BD). Unsafe sex and unplanned pregnancies are serious problems in clinical practice. The aim of this study was to investigate impulsivity levels, contraception methods, and levels of planned pregnancies among women with bipolar an...

journal_title：Neuropsychiatric disease and treatment

authors： Zengin Eroglu M,Lus MG

更新日期：2020-02-07 00:00:00

abstract：Purpose:Stroke remains the primary cause of pain, suffering, and death in patients. One of the major thrusts in stroke therapy is to find an effective prevention strategy. Objectives of this study are to testify the neuro-protection effect of stigmasterol in ischemic/reperfusion injury model. Methods:The dosage-depend...

journal_title：Neuropsychiatric disease and treatment

authors： Sun J,Li X,Liu J,Pan X,Zhao Q

更新日期：2019-10-18 00:00:00

abstract：BACKGROUND:Although most patients with relapsing-remitting multiple sclerosis (RRMS) will develop secondary progressive multiple sclerosis (SPMS), little is known about the burden of multiple sclerosis by disease subtype. This study describes the burden of disease in terms of demographics, disease severity, symptoms, h...

journal_title：Neuropsychiatric disease and treatment

authors： Gross HJ,Watson C

更新日期：2017-05-18 00:00:00

abstract：Objective:Ser9Gly (rs6280) is a functional single-nucleotide polymorphism (SNP) in the dopamine receptor D3 (DRD3) gene that may be associated with schizophrenia. We performed a meta-analysis to determine whether Ser9Gly influences the risk of schizophrenia and examined the relationship between the Ser9Gly SNP and the ...

journal_title：Neuropsychiatric disease and treatment

authors： Qi XL,Xuan JF,Xing JX,Wang BJ,Yao J

更新日期：2017-11-23 00:00:00

abstract：BACKGROUND:Dementia is generally characterized by cognitive impairment that can be accompanied by psychotic symptoms; for example, visual hallucinations are a core feature of dementia with Lewy bodies, and delusions are often seen in Alzheimer's disease. However, for behavioral variant of frontotemporal dementia (bvFTD...

journal_title：Neuropsychiatric disease and treatment

authors： Gossink FT,Vijverberg EG,Krudop W,Scheltens P,Stek ML,Pijnenburg YA,Dols A

更新日期：2017-04-13 00:00:00

abstract：:Traumatic brain injury (TBI) is a well recognized public health problem worldwide. TBI has previously been considered as a rare cause of hypopituitarism, but an increased prevalence of neuroendocrine dysfunction in patients with TBI has been reported during the last 15 years in most of the retrospective and prospectiv...

journal_title：Neuropsychiatric disease and treatment

authors： Tanriverdi F,Kelestimur F

更新日期：2015-07-27 00:00:00

abstract：:Lacosamide is a newly registered antiepileptic drug with dual mechanisms of action. It selectively enhances slow inactivation of voltage-gated sodium channels, resulting in stabilization of hyperexcitable neuronal membranes and inhibition of repetitive neuronal firing. It also binds to a collapsing-response mediator p...

journal_title：Neuropsychiatric disease and treatment

authors： Kelemen A,Halász P

更新日期：2010-09-07 00:00:00

abstract：BACKGROUND:Relapse is common in schizophrenia, and seriously impacts patients' quality of life and social functioning. Many factors have been identified that may potentially increase the risk of relapse. This study was designed to investigate the relapse rate in the year following hospital discharge among Chinese patie...

journal_title：Neuropsychiatric disease and treatment

authors： Xiao J,Mi W,Li L,Shi Y,Zhang H

更新日期：2015-05-08 00:00:00

abstract：:Ekbom disease (EKD), formerly known as restless legs syndrome (RLS) has affected and bothered many people over the centuries. It is one of the most prevalent neurological disorders in Europe and North-America, affecting about 10% of the population. The main characteristics are the strong urge to move, accompanied or c...

journal_title：Neuropsychiatric disease and treatment

authors： Mitchell UH

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND:Recently, the sigma-1 receptor has been shown to play a significant role in the neural transmission of mood by regulating N-methyl-D-aspartate receptors. Additionally, the sigma-1 receptor has been reported to influence cognitive functions including learning and memory. In this study, we measured plasma sigm...

journal_title：Neuropsychiatric disease and treatment

authors： Shimizu H,Takebayashi M,Tani M,Tanaka H,Yamagata B,Kurosawa K,Yamada H,Hachisu M,Hisaoka-Nakashima K,Okada-Tsuchioka M,Mimura M,Iwanami A

更新日期：2013-01-01 00:00:00

abstract：Background:Post-stroke depression (PSD) is one of the most common psychiatric diseases afflicting stroke survivors. This study was conducted to assess the efficacy of ginkgo biloba extract as augmentation of venlafaxine in treating PSD. Methods:The included PSD patients were randomly assigned into the experiment group...

journal_title：Neuropsychiatric disease and treatment

authors： Liang ZH,Jia YB,Wang ML,Li ZR,Li M,Yun YL,Zhu RX

更新日期：2019-09-03 00:00:00

abstract：Objective:Previous studies have demonstrated a potentially close relationship between mood disorders and thyroid abnormalities. The aims of this study are to investigate: 1) whether significant differences of thyroid profiles exist between manic and depressive episodes in patients with bipolar disorder (BD); 2) the imp...

journal_title：Neuropsychiatric disease and treatment

authors： Li C,Lai J,Huang T,Han Y,Du Y,Xu Y,Hu S

更新日期：2019-08-09 00:00:00

abstract：Introduction:Night-eating syndrome (NES) involves uncontrolled and most often repeated binge eating during the night. It is related with mood disorders as well as sleep disorders and it may cause obesity. Risks related to NES are obesity, binge eating disorder, bulimia nervosa, affective disorders, and sleep disorders....

journal_title：Neuropsychiatric disease and treatment

authors： Olejniczak D,Bugajec D,Staniszewska A,Panczyk M,Kielan A,Czerw A,Mańczuk M,Juszczyk G,Skonieczna J,Brytek-Matera A

更新日期：2018-06-13 00:00:00

abstract：OBJECTIVE:To examine how clinical and demographic patient baseline characteristics influence effectiveness of duloxetine versus selective serotonin reuptake inhibitor (SSRI) treatment, in real-world Japanese clinical settings of patients with major depressive disorder (MDD) and associated painful physical symptoms (PPS...

journal_title：Neuropsychiatric disease and treatment

authors： Kuga A,Tsuji T,Hayashi S,Fujikoshi S,Tokuoka H,Yoshikawa A,Escobar R,Tanaka K,Azekawa T

更新日期：2017-08-04 00:00:00

abstract：:[This retracts the article DOI: 10.2147/NDT.S214595.]. ...

journal_title：Neuropsychiatric disease and treatment

authors：

更新日期：2019-08-22 00:00:00

abstract：:A plethora of research has implicated hundreds of putative biomarkers for depression, but has not yet fully elucidated their roles in depressive illness or established what is abnormal in which patients and how biologic information can be used to enhance diagnosis, treatment and prognosis. This lack of progress is par...

journal_title：Neuropsychiatric disease and treatment

authors： Strawbridge R,Young AH,Cleare AJ

更新日期：2017-05-10 00:00:00

abstract：Background:Evidence has shown that microRNAs (miRNAs) are implicated in ischemic diseases. Therefore, the aim of the present study was to identify the functions of astrocyte (ATC)-derived exosomal miR-361 on cerebral ischemic-reperfusion (I/R) injury. Methods:A rat model of cerebral I/R injury was initially establishe...

journal_title：Neuropsychiatric disease and treatment

authors： Bu X,Li D,Wang F,Sun Q,Zhang Z

更新日期：2020-07-31 00:00:00

abstract：BACKGROUND:Antipsychotics have been used for more than 50 years in the treatment of schizophrenia and many other psychiatric disorders. Prolactin levels usually increase in patients treated with risperidone. Aripiprazole, which has a unique effect as an antipsychotic, is a D2 receptor partial agonist. It is an atypical...

journal_title：Neuropsychiatric disease and treatment

authors： Ranjbar F,Sadeghi-Bazargani H,Niari Khams P,Arfaie A,Salari A,Farahbakhsh M

更新日期：2015-03-02 00:00:00

abstract：:Orthostatic hypotension (OH) is a common condition, particularly in patients with α-synucleinopathies such as Parkinson's disease, and has a significant impact on activities of daily living and quality of life. Recent data suggest an association with cognitive impairment. Herein, we review the evidence that OH increas...

journal_title：Neuropsychiatric disease and treatment

authors： Robertson AD,Udow SJ,Espay AJ,Merola A,Camicioli R,Lang AE,Masellis M

更新日期：2019-08-02 00:00:00

abstract：:Elevation of plasma inflammatory factors in major depressive disorder (MDD) has been repeatedly observed, but contradictory results have also been reported. Alteration of complement components in MDD may also contribute to the pathophysiology of MDD by participating in inflammation. The recent findings that complement...

journal_title：Neuropsychiatric disease and treatment

authors： Wei J,Liu Y,Zhao L,Yang X,Ni P,Wang Y,Li T,Ma X

更新日期：2017-12-20 00:00:00

abstract：Objective:Stroke survivors generally have problems completing instrumental activities of daily living (IADL; eg, preparing meals, chores, taking a bath, and managing finances). However, it is unclear how stroke survivors might stave off IADL issues. Studies indicating that sleep has restorative neurological effects pro...

journal_title：Neuropsychiatric disease and treatment

authors： Seixas AA,Chung DP,Richards SL,Madhavaram S,Raghavan P,Gago J,Casimir G,Jean-Louis G

更新日期：2019-01-04 00:00:00

abstract：Objective:To investigate the baseline brain activity in neuromyelitis optica patients without brain lesion using the regional amplitude of low-frequency fluctuation (ALFF) and fractional amplitude of low-frequency fluctuation (fALFF) as indexes. Materials and methods:Forty-two patients of NMO with normal performance in ...

journal_title：Neuropsychiatric disease and treatment

authors： Liu Y,Xiong H,Li X,Zhang D,Yang C,Yu J,Liao R,Zhou B,Huang X,Tang Z

更新日期：2020-01-08 00:00:00

abstract：AIM:The relationship between psychological stress and platelet activation has been widely studied. It is well known that platelets may reflect certain biochemical changes that occur in the brain when different mental conditions occur. Platelet 5-hydroxytryptamine (5-HT) is also extensively studied in psychiatry. The me...

journal_title：Neuropsychiatric disease and treatment

authors： Göğçegöz Gül I,Eryılmaz G,Ozten E,Hızlı Sayar G

更新日期：2014-09-04 00:00:00

abstract：Background:Mental disorders affect about one-third of the human population, are typically chronic and significantly decrease the quality of life. Presently, the treatment of mental illnesses is far from adequate with a substantial proportion of the patients being pharmacoresistant and suffering from relapses. One of t...

journal_title：Neuropsychiatric disease and treatment

authors： Latalova K,Sery O,Hosakova K,Hosak L

更新日期：2020-05-06 00:00:00

abstract：:Antipsychotics are the mainstay in schizophrenia management, and long-acting injectable (LAI) antipsychotics contribute to the successful maintenance of treatment by improving non-adherence and preventing relapses. Paliperidone palmitate 3-monthly (PP3M) formulation is the only available LAI antipsychotic that offers ...

journal_title：Neuropsychiatric disease and treatment

authors： Mathews M,Gopal S,Nuamah I,Hargarter L,Savitz AJ,Kim E,Tan W,Soares B,Correll CU

更新日期：2019-05-21 00:00:00