Plasma complement component 4 increases in patients with major depressive disorder.

abstract：Background:Early-onset major depressive disorder (EO-MDD), beginning during childhood and adolescence, is associated with more illness burden and a worse prognosis than adult-onset MDD (AO-MDD), but little is known about the neural features distinguishing these subgroup phenotypes. Functional abnormalities of the amygd...

journal_title：Neuropsychiatric disease and treatment

authors： Clark DL,Konduru N,Kemp A,Bray S,Brown EC,Goodyear B,Ramasubbu R

更新日期：2018-01-14 00:00:00

abstract：Background:Various personality traits mediate the association between childhood stress and depressive symptoms in adulthood. The aim of this study was to clarify the indirect effects of the experience of child maltreatment on depressive symptoms and appraisal of life events in adulthood through trait anxiety. Subjects...

journal_title：Neuropsychiatric disease and treatment

authors： Uchida Y,Takahashi T,Katayama S,Masuya J,Ichiki M,Tanabe H,Kusumi I,Inoue T

更新日期：2018-11-27 00:00:00

abstract：:Fluvoxamine is a selective-serotonin reuptake inhibitor (SSRI) that has proved effective in large double-blind, randomized, controlled trials involving patients with social anxiety disorder (SAD), obsessive-compulsive disorder (OCD), and panic disorder. Improvements have also been demonstrated in patients with post-tr...

journal_title：Neuropsychiatric disease and treatment

authors： Irons J

更新日期：2005-12-01 00:00:00

abstract：Purpose:Impairments in intra- and inter-hemispheric information transfer circuits have been reported in patients with major depressive disorder (MDD). However, the specific anomalous connection (intra- and/or inter-hemispheric) and hemisphere (left and/or right) in which this connection plays a more dominant role in th...

journal_title：Neuropsychiatric disease and treatment

authors： Ran S,Zuo Z,Li C,Yin X,Qu W,Tang Q,Wang Y,Shi Y,Li H

更新日期：2020-06-10 00:00:00

abstract：BACKGROUND:This study aims to verify the main psychometric properties of the Italian version of the Impact of Event Scale - Revised (IES-R) in a sample of flood victims. METHODS:The sample was composed of 262 subjects involved in the natural disaster of 2009 in the city of Messina (Italy). All participants completed t...

journal_title：Neuropsychiatric disease and treatment

authors： Craparo G,Faraci P,Rotondo G,Gori A

更新日期：2013-01-01 00:00:00

abstract：:Delirium occurs in 23% of sepsis patients, in which pro-inflammatory cytokines and nitric oxide are suggested to be involved. However, in animal experiments, even a subseptic dose of lipopolysaccharide (LPS) injection induces both pro-inflammatory cytokines and inducible nitric oxide synthase in the brain, suggesting ...

journal_title：Neuropsychiatric disease and treatment

authors： Maeda S,Nakatsuka I,Hayashi Y,Higuchi H,Shimada M,Miyawaki T

更新日期：2008-06-01 00:00:00

abstract：BACKGROUND:High-dose use of benzodiazepines (BZPs) reportedly causes adverse effects on cognitive function and quality of life in patients with schizophrenia. However, effects of BZPs on the clinical course of schizophrenia have not been clarified. This study was set out to investigate the association between BZPs and ...

journal_title：Neuropsychiatric disease and treatment

authors： Takita Y,Takaesu Y,Ono K,Futenma K,Shimura A,Murakoshi A,Komada Y,Inoue Y,Inoue T

更新日期：2016-12-15 00:00:00

abstract：:Lacosamide is a newly registered antiepileptic drug with dual mechanisms of action. It selectively enhances slow inactivation of voltage-gated sodium channels, resulting in stabilization of hyperexcitable neuronal membranes and inhibition of repetitive neuronal firing. It also binds to a collapsing-response mediator p...

journal_title：Neuropsychiatric disease and treatment

authors： Kelemen A,Halász P

更新日期：2010-09-07 00:00:00

abstract：Purpose:Entropy analysis of resting-state functional magnetic resonance imaging (R-fMRI) has recently been adopted to characterize brain temporal dynamics in some neuropsychological or psychiatric diseases. Thalamus-related dysfunction might be a potential trait marker of major depressive disorder (MDD), but the abnorm...

journal_title：Neuropsychiatric disease and treatment

authors： Xue SW,Wang D,Tan Z,Wang Y,Lian Z,Sun Y,Hu X,Wang X,Zhou X

更新日期：2019-09-11 00:00:00

abstract：Background:It is known that miR-532-5p is critical for neuronal differentiation. However, the role of miR-532-5p in depression remains unknown. This study aimed to investigate the role and mechanism of miR-532-5p in major depressive disorder (MDD). Methods:The depression mice model was established by chronic unpredict...

journal_title：Neuropsychiatric disease and treatment

authors： Yan X,Zeng D,Zhu H,Zhang Y,Shi Y,Wu Y,Tang H,Li D

更新日期：2020-11-12 00:00:00

abstract：Objective:To investigate the baseline brain activity in neuromyelitis optica patients without brain lesion using the regional amplitude of low-frequency fluctuation (ALFF) and fractional amplitude of low-frequency fluctuation (fALFF) as indexes. Materials and methods:Forty-two patients of NMO with normal performance in ...

journal_title：Neuropsychiatric disease and treatment

authors： Liu Y,Xiong H,Li X,Zhang D,Yang C,Yu J,Liao R,Zhou B,Huang X,Tang Z

更新日期：2020-01-08 00:00:00

abstract：:The practice of inhaling liquefied petroleum gas (LPG) to commit suicide is uncommon and almost exclusively a prerogative of the prison population. Numerous cases of sudden deaths caused by intentional propane and/or butane inhalation have been described, but these cases survived and a description of the consequences ...

journal_title：Neuropsychiatric disease and treatment

authors： Godani M,Canavese F,Migliorini S,Del Sette M

更新日期：2015-05-06 00:00:00

abstract：INTRODUCTION:Essential tremor (ET) is the most common movement disorder in the adult population. At present ET treatment shows limited efficacy, particularly in patients with severe and disabling symptoms. This study evaluates the clinical efficacy of mirtazapine in an untreated ET patient population. MATERIALS AND ME...

journal_title：Neuropsychiatric disease and treatment

authors： Uccellini D,Grampa G,La Spina I,Nasuelli D,Neromante I,Politini L,Reverberi F,Porazzi D,Carli V,Camardese G

更新日期：2006-03-01 00:00:00

abstract：OBJECTIVE:To examine how clinical and demographic patient baseline characteristics influence effectiveness of duloxetine versus selective serotonin reuptake inhibitor (SSRI) treatment, in real-world Japanese clinical settings of patients with major depressive disorder (MDD) and associated painful physical symptoms (PPS...

journal_title：Neuropsychiatric disease and treatment

authors： Kuga A,Tsuji T,Hayashi S,Fujikoshi S,Tokuoka H,Yoshikawa A,Escobar R,Tanaka K,Azekawa T

更新日期：2017-08-04 00:00:00

abstract：Background:Schizophrenia is a debilitating psychiatric disorder characterized by molecular and anatomical abnormalities of multiple brain regions. Our recent study showed that dysbiosis of the gut microbiota contributes to the onset of schizophrenia-relevant behaviors, but the underlying mechanisms remain largely unkno...

journal_title：Neuropsychiatric disease and treatment

authors： Liang W,Huang Y,Tan X,Wu J,Duan J,Zhang H,Yin B,Li Y,Zheng P,Wei H,Xie P

更新日期：2019-11-19 00:00:00

abstract：Purpose:Sleep difficulties are common in patients with multiple sclerosis (MS), which may increase feelings of fatigue, negatively interfere with daily activities, and consequently reduce their quality of life. Studies examining the effects of sleep-targeted interventions in MS are currently limited in the literature. ...

journal_title：Neuropsychiatric disease and treatment

authors： Akbarfahimi M,Nabavi SM,Kor B,Rezaie L,Paschall E

更新日期：2020-05-29 00:00:00

abstract：Background:Cognitive dysfunction represents a distinct biological and clinical dimension in major depression disorders (MDD) and cognitive performance strongly affects psychosocial functioning in patients diagnosed with MDD. Objective:To assess which neurocognitive variables at baseline predict the functional outcome ...

journal_title：Neuropsychiatric disease and treatment

authors： Castellano S,Torrent C,Petralia MC,Godos J,Cantarella RA,Ventimiglia A,De Vivo S,Platania S,Guarnera M,Pirrone C,Drago F,Vieta E,Di Nuovo S,Popovic D,Caraci F

更新日期：2020-02-28 00:00:00

abstract：:Aripiprazole is a third generation atypical antipsychotic with compelling evidence as a highly effective treatment option in the management of acute manic and mixed episodes of bipolar I disorders. It has a unique mode of action, acting as a partial agonist at dopamine D2 and D3, and serotonin 5-HT1A; and exhibiting a...

journal_title：Neuropsychiatric disease and treatment

authors： Sayyaparaju KK,Grunze H,Fountoulakis KN

更新日期：2014-03-13 00:00:00

abstract：OBJECTIVES:Depressive symptoms are common among patients with obesity. Abnormalities in dopamine signaling involved in the reward circuit may ensue excessive consumption of food, resulting in obesity and leading to neuropsychiatric disorders such as depression. This study sought to investigate the association of polymo...

journal_title：Neuropsychiatric disease and treatment

authors： Bieliński M,Jaracz M,Lesiewska N,Tomaszewska M,Sikora M,Junik R,Kamińska A,Tretyn A,Borkowska A

更新日期：2017-08-18 00:00:00

abstract：:In Diagnostic and Statistical Manual of Mental Disorders, fifth edition, psychogenic non-epileptic seizures (PNES) do not have a unique classification as they can be found within different categories: conversion, dissociative, and somatization disorders. The ICD-10, instead, considers PNES within dissociative disorder...

journal_title：Neuropsychiatric disease and treatment

authors： Beghi M,Negrini PB,Perin C,Peroni F,Magaudda A,Cerri C,Cornaggia CM

更新日期：2015-09-30 00:00:00

abstract：OBJECTIVE:In this study, we compared the prevalence rate of non-alcoholic fatty liver disease (NAFLD) between young males with schizophrenia and the general young males as the control group, and we also investigated the risk factors of NAFLD in young males with schizophrenia. MATERIALS AND METHODS:This is a large cros...

journal_title：Neuropsychiatric disease and treatment

authors： Yan J,Hou C,Liang Y

更新日期：2017-06-12 00:00:00

abstract：OBJECTIVE:To investigate the impact of anxiety symptoms on depression outcomes in Asian patients with major depressive disorder (MDD) (n=714). METHODS:The 17-item Hamilton Depression Scale (HAMD-17), overall severity, somatic symptoms, and quality of life (QOL) (EuroQOL Questionnaire-5 Dimensions [EQ-5D]) were assesse...

journal_title：Neuropsychiatric disease and treatment

authors： Novick D,Montgomery W,Aguado J,Peng X,Haro JM

更新日期：2016-04-11 00:00:00

abstract：:Panic disorder (PD) is a disabling condition which appears in late adolescence or early adulthood and affects more frequently women than men. PD is frequently characterized by recurrences and sometimes by a chronic course and, therefore, most patients require long-term treatments to achieve remission, to prevent relap...

journal_title：Neuropsychiatric disease and treatment

authors： Marchesi C

更新日期：2008-02-01 00:00:00

abstract：Purpose:Numerous preclinical studies have demonstrated the potential neuroprotective effects of N-acetylcysteine (NAC) in the treatment of brain ischemia. Accordingly, the present study aimed to assess the potential therapeutic effects of oral NAC in patients with acute ischemic stroke. Patients and Methods:In a rando...

journal_title：Neuropsychiatric disease and treatment

authors： Sabetghadam M,Mazdeh M,Abolfathi P,Mohammadi Y,Mehrpooya M

更新日期：2020-05-18 00:00:00

abstract：:Catatonia is a serious, common syndrome of motoric and behavioral dysfunction, which carries high morbidity and mortality. Electroconvulsive therapy (ECT) is the definitive treatment for catatonia, but access to ECT for the treatment of catatonia remains inappropriately limited. Catatonia is observable, detectable, an...

journal_title：Neuropsychiatric disease and treatment

authors： Lloyd JR,Silverman ER,Kugler JL,Cooper JJ

更新日期：2020-09-25 00:00:00

abstract：Purpose:Color preferences vary among normal individuals and psychiatric patients, and this might be related to their different levels of hypnotic susceptibility. We hypothesized that individuals with higher hypnotic susceptibility prefer more arousing colors such as red. Patients and methods:Out of 440 participants, w...

journal_title：Neuropsychiatric disease and treatment

authors： Yu E,Zhu J,Tan Y,Liao Z,Qiu Y,Zhang B,Wang C,Wang W

更新日期：2018-01-30 00:00:00

abstract：Background:It has been suggested that autism spectrum disorder (ASD) might be a "comorbid" condition in selective mutism (SM). Methods:In this retrospective study, we examined medical records of children with SM diagnosis (n=97) at a medical center specializing in assessment of ASD. Results:Mean age for onset of SM s...

journal_title：Neuropsychiatric disease and treatment

authors： Steffenburg H,Steffenburg S,Gillberg C,Billstedt E

更新日期：2018-05-07 00:00:00

abstract：Purpose:This randomized, double-blind (DB), non-inferiority phase 3 study was conducted to assess the efficacy and safety of paliperidone palmitate 3-month (PP3M) vs 1-month formulation (PP1M) in European and non-European patients with schizophrenia. Patients and methods:In this randomized, DB, parallel-group study, a...

journal_title：Neuropsychiatric disease and treatment

authors： Savitz AJ,Xu H,Gopal S,Nuamah I,Ravenstijn P,Hough D,Hargarter L

更新日期：2019-02-21 00:00:00

abstract：BACKGROUND:The main aim of this study was to assess the reliability and structural validity of the French version of the 12-item version of the Personal Report of Confidence as Speaker (PRCS), one of the most promising measurements of public speaking fear. METHODS:A total of 611 French-speaking volunteers were adminis...

journal_title：Neuropsychiatric disease and treatment

authors： Heeren A,Ceschi G,Valentiner DP,Dethier V,Philippot P

更新日期：2013-01-01 00:00:00

abstract：:Functional neurological disorder (FND), a condition at the intersection of neurology and psychiatry, is a common and disabling outpatient referral to neurology and neuropsychiatry clinics. In this perspective article, we focus on the motor spectrum of FND (mFND), including individuals with functional movement disorder...

journal_title：Neuropsychiatric disease and treatment

authors： Saxena A,Godena E,Maggio J,Perez DL

更新日期：2020-09-18 00:00:00