Ataxia with Parkinsonism and dystonia after intentional inhalation of liquefied petroleum gas.

Abstract:

:The practice of inhaling liquefied petroleum gas (LPG) to commit suicide is uncommon and almost exclusively a prerogative of the prison population. Numerous cases of sudden deaths caused by intentional propane and/or butane inhalation have been described, but these cases survived and a description of the consequences is very rare. We describe a prisoner who survived after voluntary inhalation of LPG, and who developed ataxia, Parkinsonism, and dystonia. Brain MRI showed bilateral hyperintensity in the basal ganglia and in the cerebellar hemispheres. The clinical evolution and the MRI abnormalities are similar to those described in cases of poisoning by CO where the mechanism of brain injury is related to histotoxic hypoxia. We believe that LPG, considered until now a mixture of gas with low neurotoxic power, may have caused direct toxic damage to the brain, mediated by a mechanism of hypoxia, such as in CO intoxication.

authors

Godani M,Canavese F,Migliorini S,Del Sette M

doi

10.2147/NDT.S80460

subject

Has Abstract

pub_date

2015-05-06 00:00:00

pages

1157-9

eissn

1176-6328

issn

1178-2021

pii

ndt-11-1157

journal_volume

11

pub_type

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