Changes in peripheral benzodiazepine receptors in patients with bipolar disorder.

abstract：:Antipsychotics are the mainstay in schizophrenia management, and long-acting injectable (LAI) antipsychotics contribute to the successful maintenance of treatment by improving non-adherence and preventing relapses. Paliperidone palmitate 3-monthly (PP3M) formulation is the only available LAI antipsychotic that offers ...

journal_title：Neuropsychiatric disease and treatment

authors： Mathews M,Gopal S,Nuamah I,Hargarter L,Savitz AJ,Kim E,Tan W,Soares B,Correll CU

更新日期：2019-05-21 00:00:00

abstract：OBJECTIVE:To investigate the impact of anxiety symptoms on depression outcomes in Asian patients with major depressive disorder (MDD) (n=714). METHODS:The 17-item Hamilton Depression Scale (HAMD-17), overall severity, somatic symptoms, and quality of life (QOL) (EuroQOL Questionnaire-5 Dimensions [EQ-5D]) were assesse...

journal_title：Neuropsychiatric disease and treatment

authors： Novick D,Montgomery W,Aguado J,Peng X,Haro JM

更新日期：2016-04-11 00:00:00

abstract：Background:It is known that miR-532-5p is critical for neuronal differentiation. However, the role of miR-532-5p in depression remains unknown. This study aimed to investigate the role and mechanism of miR-532-5p in major depressive disorder (MDD). Methods:The depression mice model was established by chronic unpredict...

journal_title：Neuropsychiatric disease and treatment

authors： Yan X,Zeng D,Zhu H,Zhang Y,Shi Y,Wu Y,Tang H,Li D

更新日期：2020-11-12 00:00:00

abstract：BACKGROUND:The body dysmorphic disorder is prevalent in general population and in psychiatric, dermatological, and plastic-surgery patients, but there lacks a structure-validated, comprehensive self-report measure of body image concerns, which is established through both exploratory and confirmatory factor analyses. M...

journal_title：Neuropsychiatric disease and treatment

authors： He W,Zheng Q,Ji Y,Shen C,Zhu Q,Wang W

更新日期：2017-05-29 00:00:00

abstract：:Medically intractable epilepsy is associated with increased morbidity and mortality. For those with focal epilepsy and correlated electrophysiological or radiographic features, open surgical resection can achieve high rates of seizure control, but can be associated with neurologic deficits and cognitive effects. Recen...

journal_title：Neuropsychiatric disease and treatment

authors： Shukla ND,Ho AL,Pendharkar AV,Sussman ES,Halpern CH

更新日期：2017-09-26 00:00:00

abstract：BACKGROUND:Patients with schizophrenia show disturbances in both visual perception and social cognition. Perception of biological motion (BM) is a higher-level visual process, and is known to be associated with social cognition. BM induces activation in the "social brain network", including the superior temporal sulcus...

journal_title：Neuropsychiatric disease and treatment

authors： Hashimoto N,Toyomaki A,Hirai M,Miyamoto T,Narita H,Okubo R,Kusumi I

更新日期：2014-11-17 00:00:00

abstract：OBJECTIVES:Depressive symptoms are common among patients with obesity. Abnormalities in dopamine signaling involved in the reward circuit may ensue excessive consumption of food, resulting in obesity and leading to neuropsychiatric disorders such as depression. This study sought to investigate the association of polymo...

journal_title：Neuropsychiatric disease and treatment

authors： Bieliński M,Jaracz M,Lesiewska N,Tomaszewska M,Sikora M,Junik R,Kamińska A,Tretyn A,Borkowska A

更新日期：2017-08-18 00:00:00

abstract：BACKGROUND:Following the approval of lisdexamfetamine dimesylate (LDX) in several European countries for the treatment of attention-deficit/hyperactivity disorder (ADHD) in children and adolescents with an inadequate response to methylphenidate (MPH) treatment, the aim of the present analysis was to establish the respo...

journal_title：Neuropsychiatric disease and treatment

authors： Coghill DR,Banaschewski T,Lecendreux M,Soutullo C,Zuddas A,Adeyi B,Sorooshian S

更新日期：2014-10-29 00:00:00

abstract：BACKGROUND:Recently, the sigma-1 receptor has been shown to play a significant role in the neural transmission of mood by regulating N-methyl-D-aspartate receptors. Additionally, the sigma-1 receptor has been reported to influence cognitive functions including learning and memory. In this study, we measured plasma sigm...

journal_title：Neuropsychiatric disease and treatment

authors： Shimizu H,Takebayashi M,Tani M,Tanaka H,Yamagata B,Kurosawa K,Yamada H,Hachisu M,Hisaoka-Nakashima K,Okada-Tsuchioka M,Mimura M,Iwanami A

更新日期：2013-01-01 00:00:00

abstract：:Ekbom disease (EKD), formerly known as restless legs syndrome (RLS) has affected and bothered many people over the centuries. It is one of the most prevalent neurological disorders in Europe and North-America, affecting about 10% of the population. The main characteristics are the strong urge to move, accompanied or c...

journal_title：Neuropsychiatric disease and treatment

authors： Mitchell UH

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND:Concurrent personality disorder (PD) and substance use disorder (SUD) are common in clinical practice. However, SUD is the main criterion for study exclusion in most psychotherapeutic studies of PD. As a result, data on treatment outcomes in patients with concurrent PD/SUD are scarce. METHODS:The study samp...

journal_title：Neuropsychiatric disease and treatment

authors： Lana F,Sánchez-Gil C,Adroher ND,Pérez V,Feixas G,Martí-Bonany J,Torrens M

更新日期：2016-06-21 00:00:00

abstract：Objectives:The aim of this study was to investigate the association between benign paroxysmal positional vertigo (BPPV) and vertebral artery (VA) flow rates and diameters by using Doppler ultrasonography in patients with BPPV. Additionally, we aimed to investigate the abnormalities of VA values obtained by extracranial...

journal_title：Neuropsychiatric disease and treatment

authors： Yazıcı A,İnanç Y

更新日期：2018-08-06 00:00:00

abstract：BACKGROUND:We assessed the effect of switching patients with major depressive disorder to milnacipran following an initial selective serotonin reuptake inhibitor treatment failure, and explored potential biomarkers in their blood. METHODS:We conducted a prospective, open-label, 24-week trial. Depression was assessed w...

journal_title：Neuropsychiatric disease and treatment

authors： Hashimoto T,Sakurai D,Oda Y,Hasegawa T,Kanahara N,Sasaki T,Komatsu H,Takahashi J,Oiwa T,Sekine Y,Watanabe H,Iyo M

更新日期：2015-12-10 00:00:00

abstract：Background:Cognitive dysfunction represents a distinct biological and clinical dimension in major depression disorders (MDD) and cognitive performance strongly affects psychosocial functioning in patients diagnosed with MDD. Objective:To assess which neurocognitive variables at baseline predict the functional outcome ...

journal_title：Neuropsychiatric disease and treatment

authors： Castellano S,Torrent C,Petralia MC,Godos J,Cantarella RA,Ventimiglia A,De Vivo S,Platania S,Guarnera M,Pirrone C,Drago F,Vieta E,Di Nuovo S,Popovic D,Caraci F

更新日期：2020-02-28 00:00:00

abstract：:In the present study, we investigated the relationship between physical activity (PA) and self-esteem (SE), while introducing body mass index (BMI), perceived physical fitness (PPF), and body image (BI) in adults (N =264, M =38.10 years). The findings indicated that PA was directly and indirectly associated with SE. B...

journal_title：Neuropsychiatric disease and treatment

authors： Zamani Sani SH,Fathirezaie Z,Brand S,Pühse U,Holsboer-Trachsler E,Gerber M,Talepasand S

更新日期：2016-10-12 00:00:00

abstract：BACKGROUND:In Japan, the effects of reduced water, such as hydrogen-rich electrolyzed reduced water and natural reduced water, like Hita Tenryosui water®, have been examined. The purpose of the present study was to identify the role of natural reduced water in anxiety and blood biochemical analysis. MATERIALS AND METH...

journal_title：Neuropsychiatric disease and treatment

authors： Masuda K,Tanaka Y,Kanehisa M,Ninomiya T,Inoue A,Higuma H,Kawashima C,Nakanishi M,Okamoto K,Akiyoshi J

更新日期：2017-09-08 00:00:00

abstract：BACKGROUND:Multiple sclerosis (MS) is the most common chronic autoimmune demyelinating and inflammatory disease of the central nervous system, afflicting both the body and mind. The risk of suffering from MS is 2.5-3.5 times greater in females than in males. While there is extant research on fatigue, depression, and co...

journal_title：Neuropsychiatric disease and treatment

authors： Sadeghi Bahmani D,Gerber M,Kalak N,Lemola S,Clough PJ,Calabrese P,Shaygannejad V,Pühse U,Holsboer-Trachsler E,Brand S

更新日期：2016-06-27 00:00:00

abstract：BACKGROUND:Oral cholinesterase inhibitors at doses efficacious for the treatment of Alzheimer's disease (AD) are often prematurely discontinued due to gastrointestinal side effects. In controlled clinical trials, transdermal rivastigmine demonstrated less such effects at similar efficacy. The current study aimed to ver...

journal_title：Neuropsychiatric disease and treatment

authors： Seibert J,Tracik F,Articus K,Spittler S

更新日期：2012-01-01 00:00:00

abstract：OBJECTIVES:Although bipolar disorder has been understood classically as a cyclic disease with full recovery between mood episodes, in the last decade, evidence has accumulated supporting progressive features. The clinical picture of advanced or end-stage bipolar disorder is heterogeneous with possible deficits in cogni...

journal_title：Neuropsychiatric disease and treatment

authors： Dols A,Krudop W,Möller C,Shulman K,Sajatovic M,Pijnenburg YA

更新日期：2016-09-07 00:00:00

abstract：OBJECTIVE:To examine how clinical and demographic patient baseline characteristics influence effectiveness of duloxetine versus selective serotonin reuptake inhibitor (SSRI) treatment, in real-world Japanese clinical settings of patients with major depressive disorder (MDD) and associated painful physical symptoms (PPS...

journal_title：Neuropsychiatric disease and treatment

authors： Kuga A,Tsuji T,Hayashi S,Fujikoshi S,Tokuoka H,Yoshikawa A,Escobar R,Tanaka K,Azekawa T

更新日期：2017-08-04 00:00:00

abstract：Objective:This study compared the effect of levetiracetam (LEV) as monotherapy to sodium valproate (VPA) as monotherapy on cognitive functions in patients with epilepsy. Methods:This was a comparative prospective study on 50 patients with newly diagnosed epilepsy started on antiseizure medications. Patients were selec...

journal_title：Neuropsychiatric disease and treatment

authors： El Sabaa RM,Hamdi E,Hamdy NA,Sarhan HA

更新日期：2020-08-11 00:00:00

abstract：:The aim of this study was to explore the impact of mental illness among patients with migraine. We performed MedLine and PsycINFO searches from 1980 to 2008. Research has systematically documented a strong bidirectional association between migraine and psychiatric disorders. The relationship between migraine and psych...

journal_title：Neuropsychiatric disease and treatment

authors： Pompili M,Serafini G,Di Cosimo D,Dominici G,Innamorati M,Lester D,Forte A,Girardi N,De Filippis S,Tatarelli R,Martelletti P

更新日期：2010-04-07 00:00:00

abstract：Objective:Our study aimed to estimate the frequency of inborn errors of metabolism (IEMs) in patients presenting with acute encephalopathy-like picture at an emergency department (ED). Subjects and methods:Our study was a prospective observational study conducted on 30 patients admitted to the pediatric ED with unexpl...

journal_title：Neuropsychiatric disease and treatment

authors： Abdel Maksoud M,ELsayed SM,Shatla RH,Imam AA,Elsayed RM,Mosabah AA,Sherif AM

更新日期：2018-06-29 00:00:00

abstract：INTRODUCTION:Antipsychotics are recommended as first-line therapy for acute mania and maintenance treatment of bipolar disorder; however, published literature suggests their real-world use remains limited. Understanding attitudes toward these medications may help identify barriers and inform personalized therapy. This ...

journal_title：Neuropsychiatric disease and treatment

authors： Sajatovic M,DiBiasi F,Legacy SN

更新日期：2017-08-30 00:00:00

abstract：:Restless legs syndrome (RLS) is one of the commonest movement disorders affecting sleep and also daytime functioning. The prevalence may be 8%-10% of the white Caucasian population. The diagnosis is simple and is based on a well-validated clinical questionnaire, yet misdiagnosis is common and the condition remains und...

journal_title：Neuropsychiatric disease and treatment

authors： Byrne R,Sinha S,Chaudhuri KR

更新日期：2006-06-01 00:00:00

abstract：PURPOSE:Infant resting-state networks do not exhibit the same connectivity patterns as those of young children and adults. Current theories of brain development emphasize developmental progression in regional and network specialization. We compared infant and adult functional connectivity, predicting that infants would...

journal_title：Neuropsychiatric disease and treatment

authors： Wylie KP,Rojas DC,Ross RG,Hunter SK,Maharajh K,Cornier MA,Tregellas JR

更新日期：2014-07-21 00:00:00

abstract：:Stem cells are self-renewing undifferentiated cells that give rise to multiple types of specialized cells of the body. In the adult, stem cells are multipotents and contribute to homeostasis of the tissues and regeneration after injury. Until recently, it was believed that the adult brain was devoid of stem cells, hen...

journal_title：Neuropsychiatric disease and treatment

authors： Taupin P

更新日期：2007-12-01 00:00:00

abstract：Purpose:Paliperidone extended release (ER) is an oral psychotropic treatment formulated to release paliperidone at a controlled, gradually ascending rate. We evaluated the efficacy and safety of switching to paliperidone ER in Taiwanese patients with schizophrenia who were unresponsive or intolerant to previous antipsy...

journal_title：Neuropsychiatric disease and treatment

authors： Chen CY,Tang TC,Chen TT,Bai YM,Tsai HH,Chen HL,Huang CJ,Chen CK,Chen CC,Hsiao MC,Liu CY,Yeh HS,Chiu NY,Hsiao CC,Chen CS,Su TP

更新日期：2018-03-08 00:00:00

abstract：:Panic disorder (PD) is a disabling condition which appears in late adolescence or early adulthood and affects more frequently women than men. PD is frequently characterized by recurrences and sometimes by a chronic course and, therefore, most patients require long-term treatments to achieve remission, to prevent relap...

journal_title：Neuropsychiatric disease and treatment

authors： Marchesi C

更新日期：2008-02-01 00:00:00

abstract：BACKGROUND:The primary objective of this prospective observational study was to evaluate changes in self-reported disability in patients with anxiety or mood disorders 3 months after initiating antidepressant treatment. METHODS:This study included 8396 patients consulting 2433 general practitioners in France for a maj...

journal_title：Neuropsychiatric disease and treatment

authors： Gérard A,Liard F,Crochard A,Goni S,Millet B

更新日期：2012-01-01 00:00:00