Adult neural stem cells: The promise of the future.

abstract：Objective:Stem cell transplantation is a promising strategy with great potential to treat Parkinson's disease (PD). Nevertheless, improving the cell delivery route and optimising implanted cells are necessary to increase the therapeutic effect. Herein, we investigated whether intranasal delivery of bone marrow stromal ...

journal_title：Neuropsychiatric disease and treatment

authors： Tang Y,Han L,Bai X,Liang X,Zhao J,Huang F,Wang J

更新日期：2020-01-23 00:00:00

abstract：:Autistic spectrum disorder (ASD) is a neurodevelopmental disorder and has a high prevalence in children. Recently, mitochondrial oxidative stress has been proposed to be associated with ASD. Besides, SIRT1/PGC-1α signaling plays an important role in combating oxidative stress. In this study, we sought to determine the...

journal_title：Neuropsychiatric disease and treatment

authors： Bu X,Wu,Lu X,Yang L,Xu X,Wang J,Tang J

更新日期：2017-06-23 00:00:00

abstract：:Ischemic stroke is one of the leading causes of brain disease, with high morbidity, disability, and mortality. MicroRNAs (miRNAs) have been identified as vital gene regulators in various types of human diseases. Accumulating evidence has suggested that aberrant expression of miRNAs play critical roles in the pathologi...

journal_title：Neuropsychiatric disease and treatment

authors： Yao S,Tang B,Li G,Fan R,Cao F

更新日期：2016-12-05 00:00:00

abstract：BACKGROUND:Latest studies show that low-energy extracorporeal shock wave therapy (ESWT) can upregulate levels of vascular endothelial growth factor (VEGF). VEGF can ease nervous tissue harm after spinal cord injury (SCI). This study aims to explore whether low-energy ESWT can promote expression of VEGF, protect nervous...

journal_title：Neuropsychiatric disease and treatment

authors： Wang L,Jiang Y,Jiang Z,Han L

更新日期：2016-08-31 00:00:00

abstract：:Autism spectrum disorder (ASD) is a common neurodevelopmental disorder characterized by pervasive difficulties since early childhood across reciprocal social communication and restricted, repetitive interests and behaviors. Although early ASD research focused primarily on children, there is increasing recognition that...

journal_title：Neuropsychiatric disease and treatment

authors： Murphy CM,Wilson CE,Robertson DM,Ecker C,Daly EM,Hammond N,Galanopoulos A,Dud I,Murphy DG,McAlonan GM

更新日期：2016-07-07 00:00:00

abstract：BACKGROUND:Relapse is common in schizophrenia, and seriously impacts patients' quality of life and social functioning. Many factors have been identified that may potentially increase the risk of relapse. This study was designed to investigate the relapse rate in the year following hospital discharge among Chinese patie...

journal_title：Neuropsychiatric disease and treatment

authors： Xiao J,Mi W,Li L,Shi Y,Zhang H

更新日期：2015-05-08 00:00:00

abstract：:Depression is a major psychiatric disorder. The standard treatment for depression is antidepressant medication, but the responses to antidepressant treatment are only partial, even poor, among 30%-45% of patients. Refractory depression is defined as depression that does not respond to antidepressant therapy after 4 we...

journal_title：Neuropsychiatric disease and treatment

authors： Chen SJ,Chang CH,Tsai HC,Chen ST,Lin CCh

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:The size and increasing burden of disease due to mental disorders in Europe poses substantial challenges to its population and to the health policy of the European Union. This warrants a specific research agenda concerning clinical mental health research as one of the cornerstones of sustainable mental healt...

journal_title：Neuropsychiatric disease and treatment

authors： van der Feltz-Cornelis CM,van Os J,Knappe S,Schumann G,Vieta E,Wittchen HU,Lewis SW,Elfeddali I,Wahlbeck K,Linszen D,Obradors-Tarragó C,Haro JM

更新日期：2014-06-27 00:00:00

abstract：BACKGROUND:In the current Japanese payment system for the treatment of psychiatric inpatients, the length of hospital stay and nurse staffing levels are key determinants of the amount of payment. These factors do not fully reflect the costs of care for each patient. The objective of this study was to clarify the relati...

journal_title：Neuropsychiatric disease and treatment

authors： Sugibayashi Y,Yoshimura K,Yamauchi K,Inagaki A,Ikegami N

更新日期：2014-08-25 00:00:00

abstract：Objective:Previous studies have demonstrated a potentially close relationship between mood disorders and thyroid abnormalities. The aims of this study are to investigate: 1) whether significant differences of thyroid profiles exist between manic and depressive episodes in patients with bipolar disorder (BD); 2) the imp...

journal_title：Neuropsychiatric disease and treatment

authors： Li C,Lai J,Huang T,Han Y,Du Y,Xu Y,Hu S

更新日期：2019-08-09 00:00:00

abstract：PURPOSE:Akathisia remains a common side effect especially from antipsychotic medication. If the condition is diagnosed the management options are limited. SUBJECTS/METHODOLOGY: We tested a structured relaxation program on nine patients with a diagnosis of schizophrenia suffering from akathisia. All patients were rated ...

journal_title：Neuropsychiatric disease and treatment

authors： Hansen LK,L'allemand T,Thiry F,Baldwin DS

更新日期：2010-05-25 00:00:00

abstract：OBJECTIVES:Depressive symptoms are common among patients with obesity. Abnormalities in dopamine signaling involved in the reward circuit may ensue excessive consumption of food, resulting in obesity and leading to neuropsychiatric disorders such as depression. This study sought to investigate the association of polymo...

journal_title：Neuropsychiatric disease and treatment

authors： Bieliński M,Jaracz M,Lesiewska N,Tomaszewska M,Sikora M,Junik R,Kamińska A,Tretyn A,Borkowska A

更新日期：2017-08-18 00:00:00

abstract：Background:Alarming somatic symptoms, in particular, cardiovascular symptoms, are the characteristic feature of panic attacks. Increased cardiac mortality and morbidity have been found in these patients. Power spectral analysis of electrocardiogram R-R intervals is known to be a particularly successful tool in the dete...

journal_title：Neuropsychiatric disease and treatment

authors： Kotianova A,Kotian M,Slepecky M,Chupacova M,Prasko J,Tonhajzerova I

更新日期：2018-02-07 00:00:00

abstract：Background:It is known that miR-532-5p is critical for neuronal differentiation. However, the role of miR-532-5p in depression remains unknown. This study aimed to investigate the role and mechanism of miR-532-5p in major depressive disorder (MDD). Methods:The depression mice model was established by chronic unpredict...

journal_title：Neuropsychiatric disease and treatment

authors： Yan X,Zeng D,Zhu H,Zhang Y,Shi Y,Wu Y,Tang H,Li D

更新日期：2020-11-12 00:00:00

abstract：OBJECTIVE OF THE STUDY:To evaluate the value of serum creatine phosphokinase-brain specific (CK-BB) and urinary lactate/creatinine (L/C) ratio as early indicators of brain damage in full-term newborns with hypoxic ischemic encephalopathy (HIE). PATIENTS AND METHODS:A case-control study including 25 full-term new-born ...

journal_title：Neuropsychiatric disease and treatment

authors： Alkholy UM,Abdalmonem N,Zaki A,Ali YF,Mohamed SA,Abdelsalam NI,Hashim MIA,Sekkien MA,Elsherbiny YM

更新日期：2017-08-08 00:00:00

abstract：BACKGROUND:To assess the efficacy and safety of oxcarbazepine (OXC) in the treatment of children with epilepsy. METHODS:Randomized controlled trials (RCTs) published in PubMed, Embase, Web of Science, Cochrane Library, Scopus, SinoMed (Chinese BioMedical Literature Service System, China), and Chinese National Knowledg...

journal_title：Neuropsychiatric disease and treatment

authors： Geng H,Wang C

更新日期：2017-03-02 00:00:00

abstract：BACKGROUND:Oral cholinesterase inhibitors at doses efficacious for the treatment of Alzheimer's disease (AD) are often prematurely discontinued due to gastrointestinal side effects. In controlled clinical trials, transdermal rivastigmine demonstrated less such effects at similar efficacy. The current study aimed to ver...

journal_title：Neuropsychiatric disease and treatment

authors： Seibert J,Tracik F,Articus K,Spittler S

更新日期：2012-01-01 00:00:00

abstract：:Abnormal prion proteins are responsible for several fatal neurodegenerative diseases in humans and in animals, including Creutzfeldt-Jakob disease (CJD), Gerstmann-Sträussler-Scheinker disease, and fatal familial insomnia. Genetics is important in prion diseases, but in the most cases, cause of diseases remained unkno...

journal_title：Neuropsychiatric disease and treatment

authors： Bagyinszky E,Giau VV,Youn YC,An SSA,Kim S

更新日期：2018-08-14 00:00:00

abstract：:Quetiapine is an atypical antipsychotic agent which is also prescribed for delirium due to its anti-dopaminergic effects; aphasia is an unusual side effect associated with the drug. Here, we report the case of an 83-year-old woman who was prescribed quetiapine (50 mg per day) for delirium. Unexpected, global aphasia o...

journal_title：Neuropsychiatric disease and treatment

authors： Chien CF,Huang P,Hsieh SW

更新日期：2017-08-28 00:00:00

abstract：INTRODUCTION:Essential tremor (ET) is the most common movement disorder in the adult population. At present ET treatment shows limited efficacy, particularly in patients with severe and disabling symptoms. This study evaluates the clinical efficacy of mirtazapine in an untreated ET patient population. MATERIALS AND ME...

journal_title：Neuropsychiatric disease and treatment

authors： Uccellini D,Grampa G,La Spina I,Nasuelli D,Neromante I,Politini L,Reverberi F,Porazzi D,Carli V,Camardese G

更新日期：2006-03-01 00:00:00

abstract：Background:Mental disorders affect about one-third of the human population, are typically chronic and significantly decrease the quality of life. Presently, the treatment of mental illnesses is far from adequate with a substantial proportion of the patients being pharmacoresistant and suffering from relapses. One of t...

journal_title：Neuropsychiatric disease and treatment

authors： Latalova K,Sery O,Hosakova K,Hosak L

更新日期：2020-05-06 00:00:00

abstract：BACKGROUND:Decreased relapse rate and slower disease progression have been reported with long-term use of immunomodulatory treatments (IMTs, interferon beta or glatiramer acetate) in relapsing-remitting multiple sclerosis. There are, however, patients who do not respond to such treatments, and they can be potential can...

journal_title：Neuropsychiatric disease and treatment

authors： Mezei Z,Bereczki D,Racz L,Csiba L,Csepany T

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Published data on the relationship of hormone replacement therapy (HRT) with Parkinson's disease (PD) were inconclusive. Thus, a systematic meta-analysis of observational studies was performed to clarify this topic. METHODS:The databases of PubMed and EMBASE were searched for case-control or coh...

journal_title：Neuropsychiatric disease and treatment

authors： Wang P,Li J,Qiu S,Wen H,Du J

更新日期：2014-12-31 00:00:00

abstract：:Objective: Fibromyalgia syndrome (FMS) is a chronic disorder associated with severe pain. According to the National Fibromyalgia Association, the prevalence of FMS is between 3% and 6% in the general population, with about 90% of the patients being women. The primary goal of this study was to evaluate the relationship...

journal_title：Neuropsychiatric disease and treatment

authors： Amin OA,Abouzeid SM,Ali SA,Amin BA,Alswat KA

更新日期：2019-05-27 00:00:00

abstract：:An 87-year-old woman had both Lewy body dementia and normal pressure hydrocephalus simultaneously. One should not automatically exclude the possibility of normal pressure hydrocephalus simply because another neurodegenerative disorder is present, especially if the second disorder masks typical symptoms of normal press...

journal_title：Neuropsychiatric disease and treatment

authors： Alisky J

更新日期：2008-02-01 00:00:00

abstract：INTRODUCTION:Prompt administration of antipsychotic treatment that is adhered to is essential for the optimal treatment of schizophrenia. Many patients have benefited from the advent of second-generation antipsychotics, which can offer good symptomatic control with reduced incidence of extrapyramidal symptoms, although...

journal_title：Neuropsychiatric disease and treatment

authors： Juckel G,de Bartolomeis A,Gorwood P,Mosolov S,Pani L,Rossi A,Sanjuan J

更新日期：2014-09-24 00:00:00

abstract：BACKGROUND:Articulation disorders in young children are due to defects occurring at a certain stage in sensory and motor development. Some children with functional articulation disorders may also have sensory integration dysfunction (SID). We hypothesized that speech therapy would be less efficacious in children with S...

journal_title：Neuropsychiatric disease and treatment

authors： Tung LC,Lin CK,Hsieh CL,Chen CC,Huang CT,Wang CH

更新日期：2013-01-01 00:00:00

abstract：Objective:Many previous studies have demonstrated that neuromyelitis optica (NMO) patients have abnormalities of brain anatomy and function. However, differences in spontaneous brain activity between myelin oligodendrocyte glycoprotein (MOG)-IgG ON and aquaporin 4(AQP4)-neuromyelitis optica-optic neuritis (ON) remain u...

journal_title：Neuropsychiatric disease and treatment

authors： Wang J,Tian Y,Shao Y,Feng H,Qin L,Xu W,Liu H,Xu Q,Wei S,Ma L

更新日期：2017-10-24 00:00:00

abstract：:A plethora of research has implicated hundreds of putative biomarkers for depression, but has not yet fully elucidated their roles in depressive illness or established what is abnormal in which patients and how biologic information can be used to enhance diagnosis, treatment and prognosis. This lack of progress is par...

journal_title：Neuropsychiatric disease and treatment

authors： Strawbridge R,Young AH,Cleare AJ

更新日期：2017-05-10 00:00:00

abstract：:To determine relationships between the need for dental treatments of institutionalized elderly people and cognitive impairment and the general level of care needed. Two hundred and sixty-eight residents of long-term care facilities in Germany were included in this study. Age, sex, diseases, number of frequently taken ...

journal_title：Neuropsychiatric disease and treatment

authors： Zenthöfer A,Rammelsberg P,Cabrera T,Hassel AJ

更新日期：2014-12-02 00:00:00