Reversible global aphasia as a side effect of quetiapine: a case report and literature review.

Abstract:

:Quetiapine is an atypical antipsychotic agent which is also prescribed for delirium due to its anti-dopaminergic effects; aphasia is an unusual side effect associated with the drug. Here, we report the case of an 83-year-old woman who was prescribed quetiapine (50 mg per day) for delirium. Unexpected, global aphasia occurred 3 days after treatment began. Complete recovery occurred following discontinuation of the drug. A brain computed tomography scan excluded intracranial hemorrhage and the laboratory results confirmed that no exacerbation of infection or electrolyte imbalances were present. During the aphasic episode, the patient's condition did not deteriorate and no new neurological symptoms occurred. We suspect that the occurrence of aphasia was directly due to an adverse reaction to quetiapine. To our knowledge, this is the first case report of reversible, global aphasia as a side effect of quetiapine. We propose that this occurrence of aphasia may be due to the action of quetiapine as a dopamine receptor antagonist. Clinicians should use quetiapine with caution, especially in elderly patients. On observation of aphasia, a review of the patient's medical history is required to assess for the usage of quetiapine.

authors

Chien CF,Huang P,Hsieh SW

doi

10.2147/NDT.S141273

subject

Has Abstract

pub_date

2017-08-28 00:00:00

pages

2257-2260

eissn

1176-6328

issn

1178-2021

pii

ndt-13-2257

journal_volume

13

pub_type

  • Changes of serum uric acid and total bilirubin in elderly patients with major postischemic stroke depression.

    abstract:Background:This was a longitudinal study which investigated the relationship between serum uric acid (SUA) and total bilirubin (Tbil) upon admission in elderly stroke patients and the occurrence of postischemic stroke depression (IPSD) at 3, 6, and 9 months of post-stroke follow-up. Subjects and methods:Data were anal...

    journal_title:Neuropsychiatric disease and treatment

    pub_type: 杂志文章

    doi:10.2147/NDT.S149712

    authors: Gao J,Xu W,Han K,Zhu L,Gao L,Shang X

    更新日期:2017-12-27 00:00:00

  • Effectiveness of methylphenidate as augmentation therapy after failure of adjunctive neuromodulation for patients with treatment-refractory bipolar depression: a case report.

    abstract::Adjunctive use of methylphenidate, a central stimulant, has been considered as a potential therapeutic choice for patients with refractory unipolar, geriatric, or bipolar depression, and depression secondary to medical illness. We present a case of bipolar depression in which the patient responded significantly to aug...

    journal_title:Neuropsychiatric disease and treatment

    pub_type:

    doi:10.2147/NDT.S58644

    authors: Adida M,Azorin JM

    更新日期:2014-04-02 00:00:00

  • The abnormal activation of D1R/Shp-2 complex involved in levodopa-induced dyskinesia in 6-hydroxydopamine-lesioned Parkinson's rats.

    abstract:Background:Levodopa-induced dyskinesia (LID) is a troublesome problem in the treatment of Parkinson's disease (PD). The mechanisms of LID are still mysterious. Recently, the interaction between Shp-2 and D1 dopamine receptor (D1R) has been identified to be indispensable in the D1R-mediated extracellular signal-regulate...

    journal_title:Neuropsychiatric disease and treatment

    pub_type: 杂志文章

    doi:10.2147/NDT.S162562

    authors: Wu N,Wan Y,Song L,Qi C,Liu Z,Gan J

    更新日期:2018-07-05 00:00:00

  • Lithium and neuroprotection: translational evidence and implications for the treatment of neuropsychiatric disorders.

    abstract::In the last two decades, a growing body of evidence has shown that lithium has several neuroprotective effects. Several neurobiological mechanisms have been proposed to underlie these clinical effects. Evidence from preclinical studies suggests that neuroprotection induced by lithium is mainly related to its potent in...

    journal_title:Neuropsychiatric disease and treatment

    pub_type: 杂志文章

    doi:10.2147/NDT.S33086

    authors: Diniz BS,Machado-Vieira R,Forlenza OV

    更新日期:2013-01-01 00:00:00

  • The Health-Related Quality of Life, Work Productivity, Healthcare Resource Utilization, and Economic Burden Associated with Levels of Suicidal Ideation Among Patients Self-Reporting Moderately Severe or Severe Major Depressive Disorder in a National Surve

    abstract:Background:Suicidal ideation (SI) is a cardinal aspect of major depressive disorder (MDD); however, patient-reported outcomes data from large-scale surveys are limited concerning SI in the context of MDD. This study aims to understand the association between varying levels of SI and health-related quality of life (HRQo...

    journal_title:Neuropsychiatric disease and treatment

    pub_type: 杂志文章

    doi:10.2147/NDT.S229530

    authors: Benson C,Singer D,Carpinella CM,Shawi M,Alphs L

    更新日期:2021-01-18 00:00:00

  • Effectiveness and tolerability of transdermal rivastigmine in the treatment of Alzheimer's disease in daily practice.

    abstract:BACKGROUND:Oral cholinesterase inhibitors at doses efficacious for the treatment of Alzheimer's disease (AD) are often prematurely discontinued due to gastrointestinal side effects. In controlled clinical trials, transdermal rivastigmine demonstrated less such effects at similar efficacy. The current study aimed to ver...

    journal_title:Neuropsychiatric disease and treatment

    pub_type: 杂志文章

    doi:10.2147/NDT.S29116

    authors: Seibert J,Tracik F,Articus K,Spittler S

    更新日期:2012-01-01 00:00:00

  • Attachment styles in children affected by migraine without aura.

    abstract:BACKGROUND:In recent years, great attention has been given to the presence of psychological problems and psychiatric comorbidity that are also present in children affected by primary headaches. The relationship between pain and attachment has been identified, and it may be that pain perception may change in relation wi...

    journal_title:Neuropsychiatric disease and treatment

    pub_type: 杂志文章

    doi:10.2147/NDT.S52716

    authors: Esposito M,Parisi L,Gallai B,Marotta R,Di Dona A,Lavano SM,Roccella M,Carotenuto M

    更新日期:2013-01-01 00:00:00

  • Optimal management of ADHD in older adults.

    abstract:BACKGROUND:The manifestation of attention-deficit/hyperactivity disorder (ADHD) among older adults has become an interesting topic of interest due to an increasing number of adults aged 50 years and older (≥50 years) seeking assessment for ADHD. Unfortunately, there is a lack of research on ADHD in older adults, and un...

    journal_title:Neuropsychiatric disease and treatment

    pub_type: 杂志文章,评审

    doi:10.2147/NDT.S59271

    authors: Torgersen T,Gjervan B,Lensing MB,Rasmussen K

    更新日期:2016-01-08 00:00:00

  • Development of a Body Image Concern Scale using both exploratory and confirmatory factor analyses in Chinese university students.

    abstract:BACKGROUND:The body dysmorphic disorder is prevalent in general population and in psychiatric, dermatological, and plastic-surgery patients, but there lacks a structure-validated, comprehensive self-report measure of body image concerns, which is established through both exploratory and confirmatory factor analyses. M...

    journal_title:Neuropsychiatric disease and treatment

    pub_type: 杂志文章

    doi:10.2147/NDT.S138762

    authors: He W,Zheng Q,Ji Y,Shen C,Zhu Q,Wang W

    更新日期:2017-05-29 00:00:00

  • Effect of acetazolamide for long-lasting paroxysmal dystonia in a patient with multiple sclerosis: a case report and review of literature.

    abstract::Dystonia is a rare manifestation of multiple sclerosis (MS), but it always interferes with the functional performance and quality of life. We report a rare case of long-lasting paroxysmal dystonia associated with MS. The patient was a 40-year-old woman with relapsing- remitting MS for 6 years. During the latest attack...

    journal_title:Neuropsychiatric disease and treatment

    pub_type:

    doi:10.2147/NDT.S43688

    authors: Hsieh PC,Chen SM,Guo YH,Kuan TS,Yen WJ,Chang WC,Lin YC

    更新日期:2013-01-01 00:00:00

  • Restless legs syndrome: diagnosis and review of management options.

    abstract::Restless legs syndrome (RLS) is one of the commonest movement disorders affecting sleep and also daytime functioning. The prevalence may be 8%-10% of the white Caucasian population. The diagnosis is simple and is based on a well-validated clinical questionnaire, yet misdiagnosis is common and the condition remains und...

    journal_title:Neuropsychiatric disease and treatment

    pub_type: 杂志文章

    doi:10.2147/nedt.2006.2.2.155

    authors: Byrne R,Sinha S,Chaudhuri KR

    更新日期:2006-06-01 00:00:00

  • Lisdexamfetamine in the treatment of moderate-to-severe binge eating disorder in adults: systematic review and exploratory meta-analysis of publicly available placebo-controlled, randomized clinical trials.

    abstract:BACKGROUND:Preliminary placebo-controlled evidence paved the ground to the US Food and Drug Administration approval extension of lisdexamfetamine for the treatment of moderate-to-severe binge eating disorder (BED) in adults. OBJECTIVES:To provide a preliminary qualitative and quantitative synthesis of the placebo-cont...

    journal_title:Neuropsychiatric disease and treatment

    pub_type: 杂志文章

    doi:10.2147/NDT.S109637

    authors: Fornaro M,Solmi M,Perna G,De Berardis D,Veronese N,Orsolini L,Ganança L,Stubbs B

    更新日期:2016-07-25 00:00:00

  • Long noncoding RNA CASC2 predicts the prognosis of glioma patients and functions as a suppressor for gliomas by suppressing Wnt/β-catenin signaling pathway.

    abstract:BACKGROUND:Previous studies have demonstrated that long noncoding RNA cancer susceptibility candidate 2 (lncRNA CASC2) is frequently downregulated in several types of tumors and functions as a tumor-suppressive factor. However, the clinical significance and function of CASC2 in human glioma remain largely unknown. The ...

    journal_title:Neuropsychiatric disease and treatment

    pub_type: 杂志文章

    doi:10.2147/NDT.S137171

    authors: Wang R,Li Y,Zhu G,Tian B,Zeng W,Yang Y,Li Z

    更新日期:2017-07-11 00:00:00

  • Frequencies of circulating B- and T-lymphocytes as indicators for stroke outcomes.

    abstract:BACKGROUND:Stroke has high mortality and morbidity. Biomarkers are required for to predict stroke outcomes, which could help clinicians to provide rationale approaches for patient management. The dynamic changes in circulating immune cells have been reported in stroke patients and animal models of stroke. AIM:The aim ...

    journal_title:Neuropsychiatric disease and treatment

    pub_type: 杂志文章

    doi:10.2147/NDT.S148073

    authors: Wang Y,Liu J,Wang X,Liu Z,Li F,Chen F,Geng X,Ji Z,Du H,Hu X

    更新日期:2017-10-03 00:00:00

  • The modern perspective for long-acting injectables antipsychotics in the patient-centered care of schizophrenia.

    abstract::Schizophrenia is a chronic syndrome involving different clinical dimensions, and causes significant disability with a negative impact on the quality of life of patients and their caregivers. Current guidelines for the treatment of schizophrenia focus on maximizing a patient's adaptive functioning and quality of life i...

    journal_title:Neuropsychiatric disease and treatment

    pub_type: 杂志文章

    doi:10.2147/NDT.S199048

    authors: Pietrini F,Albert U,Ballerini A,Calò P,Maina G,Pinna F,Vaggi M,Boggian I,Fontana M,Moro C,Carpiniello B

    更新日期:2019-04-30 00:00:00

  • Hormone replacement therapy and Parkinson's disease risk in women: a meta-analysis of 14 observational studies.

    abstract:BACKGROUND AND PURPOSE:Published data on the relationship of hormone replacement therapy (HRT) with Parkinson's disease (PD) were inconclusive. Thus, a systematic meta-analysis of observational studies was performed to clarify this topic. METHODS:The databases of PubMed and EMBASE were searched for case-control or coh...

    journal_title:Neuropsychiatric disease and treatment

    pub_type: 杂志文章

    doi:10.2147/NDT.S69918

    authors: Wang P,Li J,Qiu S,Wen H,Du J

    更新日期:2014-12-31 00:00:00

  • Reversion From Mild Cognitive Impairment To Normal Cognition: False-Positive Error Or True Restoration Thanks To Cognitive Control Ability?

    abstract:Purpose:Relatively little attention has been paid to the meaning of reversion from mild cognitive impairment (MCI) to cognitively normal (CN), compared to MCI progression studies. The purpose of the study was to investigate the characteristics contributing to reversion from MCI to CN and to identify the associated fact...

    journal_title:Neuropsychiatric disease and treatment

    pub_type: 杂志文章

    doi:10.2147/NDT.S223958

    authors: Chung JY,Yoon HJ,Kim H,Choi KY,Lee JJ,Lee KH,Seo EH

    更新日期:2019-10-25 00:00:00

  • Atypical depression: current perspectives.

    abstract::The history and present status of the definition, prevalence, neurobiology, and treatment of atypical depression (AD) is presented. The concept of AD has evolved through the years, and currently, in Diagnostic and Statistical Manual of Mental Disorders (DSM), Fifth Edition, the specifier of depressive episode with aty...

    journal_title:Neuropsychiatric disease and treatment

    pub_type: 杂志文章,评审

    doi:10.2147/NDT.S147317

    authors: Łojko D,Rybakowski JK

    更新日期:2017-09-20 00:00:00

  • Twelve-week physical exercise does not have a long-lasting effect on kynurenines in plasma of depressed patients.

    abstract:BACKGROUND:Physical exercise has well-characterized positive effects on depressive symptoms. The underlying biologic mechanisms are, however, far from established. A recently discovered mechanism has linked the enhanced conversion of kynurenine to kynurenic acid (KYNA) to an increased resilience toward stress-induced d...

    journal_title:Neuropsychiatric disease and treatment

    pub_type: 杂志文章

    doi:10.2147/NDT.S131746

    authors: Millischer V,Erhardt S,Ekblom Ö,Forsell Y,Lavebratt C

    更新日期:2017-03-31 00:00:00

  • Undertreatment of human immunodeficiency virus in psychiatric inpatients: a cross-sectional study of seroprevalence and associated factors.

    abstract:BACKGROUND:The aims of this study were to evaluate the prevalence of HIV and its associated demographic and clinical factors among psychiatric inpatients of a general hospital. METHODS:This was a single-center, observational, cross-sectional study that included patients consecutively admitted to our unit aged 16 years...

    journal_title:Neuropsychiatric disease and treatment

    pub_type: 杂志文章

    doi:10.2147/NDT.S79939

    authors: Gonzalez-Torres MA,Salazar MA,Imaz M,Inchausti L,Ibañez B,Fernandez-Rivas A,Pastor J,Anguiano B,Muñoz P,Ruiz E,Oraa R,Bustamante S,de Eulate SA,Cisterna R

    更新日期:2015-06-11 00:00:00

  • Abnormal functional connectivity of the posterior cingulate cortex is associated with depressive symptoms in patients with Alzheimer's disease.

    abstract:BACKGROUND:Depressive symptoms are significant and very common psychiatric complications in patients with Alzheimer's disease (AD), which can aggravate the decline in social function. However, changes in the functional connectivity (FC) of the brain in AD patients with depressive symptoms (D-AD) remain unclear. OBJECT...

    journal_title:Neuropsychiatric disease and treatment

    pub_type: 杂志文章

    doi:10.2147/NDT.S146077

    authors: Zhang J,Guo Z,Liu X,Jia X,Li J,Li Y,Lv D,Chen W

    更新日期:2017-10-11 00:00:00

  • The Impact of Event Scale - Revised: psychometric properties of the Italian version in a sample of flood victims.

    abstract:BACKGROUND:This study aims to verify the main psychometric properties of the Italian version of the Impact of Event Scale - Revised (IES-R) in a sample of flood victims. METHODS:The sample was composed of 262 subjects involved in the natural disaster of 2009 in the city of Messina (Italy). All participants completed t...

    journal_title:Neuropsychiatric disease and treatment

    pub_type: 杂志文章

    doi:10.2147/NDT.S51793

    authors: Craparo G,Faraci P,Rotondo G,Gori A

    更新日期:2013-01-01 00:00:00

  • Early stages of pediatric bipolar disorder: retrospective analysis of a Czech inpatient sample.

    abstract:BACKGROUND:Approximately 30%-60% of adults diagnosed with bipolar disorder (BD) report onset between the ages 15 and 19 years; however, a correct diagnosis is often delayed by several years. Therefore, investigations of the early features of BD are important for adequately understanding the prodromal stages of the illn...

    journal_title:Neuropsychiatric disease and treatment

    pub_type: 杂志文章

    doi:10.2147/NDT.S79586

    authors: Goetz M,Novak T,Vesela M,Hlavka Z,Brunovsky M,Povazan M,Ptacek R,Sebela A

    更新日期:2015-11-04 00:00:00

  • Lurasidone for the treatment of bipolar depression: an evidence-based review.

    abstract::Bipolar disorder (BD) is a debilitating and difficult-to-treat psychiatric disease that presents a serious burden to patients' lives as well as health care systems around the world. The essential diagnostic criterion for BD is episodes of mania or hypomania; however, the patients report that the majority of their time...

    journal_title:Neuropsychiatric disease and treatment

    pub_type: 杂志文章,评审

    doi:10.2147/NDT.S50961

    authors: Franklin R,Zorowitz S,Corse AK,Widge AS,Deckersbach T

    更新日期:2015-08-19 00:00:00

  • Increasing dependency of older people in nursing homes is associated with need for dental treatments.

    abstract::To determine relationships between the need for dental treatments of institutionalized elderly people and cognitive impairment and the general level of care needed. Two hundred and sixty-eight residents of long-term care facilities in Germany were included in this study. Age, sex, diseases, number of frequently taken ...

    journal_title:Neuropsychiatric disease and treatment

    pub_type: 杂志文章

    doi:10.2147/NDT.S71184

    authors: Zenthöfer A,Rammelsberg P,Cabrera T,Hassel AJ

    更新日期:2014-12-02 00:00:00

  • Adjunctive treatment with aripiprazole for risperidone-induced hyperprolactinemia.

    abstract:BACKGROUND:Antipsychotics have been used for more than 50 years in the treatment of schizophrenia and many other psychiatric disorders. Prolactin levels usually increase in patients treated with risperidone. Aripiprazole, which has a unique effect as an antipsychotic, is a D2 receptor partial agonist. It is an atypical...

    journal_title:Neuropsychiatric disease and treatment

    pub_type: 杂志文章

    doi:10.2147/NDT.S69088

    authors: Ranjbar F,Sadeghi-Bazargani H,Niari Khams P,Arfaie A,Salari A,Farahbakhsh M

    更新日期:2015-03-02 00:00:00

  • Quality and utilization of the Finnish clinical practice guideline in schizophrenia: evaluation using AGREE II and the vignette approach.

    abstract:Purpose:This study aims to evaluate the quality of the Finnish clinical practice guideline related to schizophrenia care and how it can be utilized in psychiatric services. Participants and methods:The data were collected from one psychiatric ward and seven psychiatric outpatient units situated in two cities in Southe...

    journal_title:Neuropsychiatric disease and treatment

    pub_type: 杂志文章

    doi:10.2147/NDT.S192752

    authors: Vähäniemi A,Välimäki M,Pekurinen V,Anttila M,Lantta T

    更新日期:2019-05-09 00:00:00

  • Milnacipran treatment and potential biomarkers in depressed patients following an initial SSRI treatment failure: a prospective, open-label, 24-week study.

    abstract:BACKGROUND:We assessed the effect of switching patients with major depressive disorder to milnacipran following an initial selective serotonin reuptake inhibitor treatment failure, and explored potential biomarkers in their blood. METHODS:We conducted a prospective, open-label, 24-week trial. Depression was assessed w...

    journal_title:Neuropsychiatric disease and treatment

    pub_type: 杂志文章

    doi:10.2147/NDT.S95067

    authors: Hashimoto T,Sakurai D,Oda Y,Hasegawa T,Kanahara N,Sasaki T,Komatsu H,Takahashi J,Oiwa T,Sekine Y,Watanabe H,Iyo M

    更新日期:2015-12-10 00:00:00

  • Risk assessment of night-eating syndrome occurrence in women in Poland, considering the obesity factor in particular.

    abstract:Introduction:Night-eating syndrome (NES) involves uncontrolled and most often repeated binge eating during the night. It is related with mood disorders as well as sleep disorders and it may cause obesity. Risks related to NES are obesity, binge eating disorder, bulimia nervosa, affective disorders, and sleep disorders....

    journal_title:Neuropsychiatric disease and treatment

    pub_type: 杂志文章

    doi:10.2147/NDT.S159562

    authors: Olejniczak D,Bugajec D,Staniszewska A,Panczyk M,Kielan A,Czerw A,Mańczuk M,Juszczyk G,Skonieczna J,Brytek-Matera A

    更新日期:2018-06-13 00:00:00

  • Autoimmune encephalitis in psychiatric institutions: current perspectives.

    abstract::Autoimmune encephalitis is a rare and newly described group of diseases involving autoantibodies directed against synaptic and neuronal cell surface antigens. It comprises a wide range of neuropsychiatric symptoms. Sensitive and specific diagnostic tests such as cell-based assay are primordial for the detection of neu...

    journal_title:Neuropsychiatric disease and treatment

    pub_type: 杂志文章,评审

    doi:10.2147/NDT.S82380

    authors: Bost C,Pascual O,Honnorat J

    更新日期:2016-10-27 00:00:00