Characterization of mutations in PRNP (prion) gene and their possible roles in neurodegenerative diseases.

abstract：BACKGROUND:Recently, the sigma-1 receptor has been shown to play a significant role in the neural transmission of mood by regulating N-methyl-D-aspartate receptors. Additionally, the sigma-1 receptor has been reported to influence cognitive functions including learning and memory. In this study, we measured plasma sigm...

journal_title：Neuropsychiatric disease and treatment

authors： Shimizu H,Takebayashi M,Tani M,Tanaka H,Yamagata B,Kurosawa K,Yamada H,Hachisu M,Hisaoka-Nakashima K,Okada-Tsuchioka M,Mimura M,Iwanami A

更新日期：2013-01-01 00:00:00

abstract：:Gerstmann's syndrome encompasses the tetrad of finger agnosia, agraphia, acalculia, and right-left confusion. An elderly man with a history of several cardiovascular diseases was initially brought to the psychiatric outpatient department by his family because of worsening of recent memory, executive function, and mixe...

journal_title：Neuropsychiatric disease and treatment

authors： Chen TY,Chen CY,Yen CH,Kuo SC,Yeh YW,Chang S,Huang SY

更新日期：2013-01-01 00:00:00

abstract：PURPOSE:The aim of this study was to ascertain the clinical characteristics of drug-induced sleep-related eating disorder (SRED). PATIENTS AND METHODS:We retrospectively reviewed the medical records of 30 patients with primary SRED (without any comorbid sleep disorders and who were not taking any possible causative me...

journal_title：Neuropsychiatric disease and treatment

authors： Komada Y,Takaesu Y,Matsui K,Nakamura M,Nishida S,Kanno M,Usui A,Inoue Y

更新日期：2016-05-26 00:00:00

abstract：Purpose:To examine the relationships of body dysmorphic disorder (BDD) with psychiatric symptoms and quality of life in dermatological patients. Patients and Methods:A total of 154 female patients with dermatological disease underwent a comprehensive clinical assessment that included the Body Dysmorphic Disorder Exami...

journal_title：Neuropsychiatric disease and treatment

authors： Chee IS,Kim HJ,Lee Y,Kim JW

更新日期：2020-12-03 00:00:00

abstract：:The practice of inhaling liquefied petroleum gas (LPG) to commit suicide is uncommon and almost exclusively a prerogative of the prison population. Numerous cases of sudden deaths caused by intentional propane and/or butane inhalation have been described, but these cases survived and a description of the consequences ...

journal_title：Neuropsychiatric disease and treatment

authors： Godani M,Canavese F,Migliorini S,Del Sette M

更新日期：2015-05-06 00:00:00

abstract：BACKGROUND:PULSE was a large, observational, multicenter study designed to evaluate the efficacy and safety of agomelatine in the treatment of major depression in patients with cardiovascular disease (CVD). METHODS:Patients with mild-to-moderate major depressive episodes, without psychotic symptoms, were treated as ou...

journal_title：Neuropsychiatric disease and treatment

authors： Medvedev VE

更新日期：2017-04-21 00:00:00

abstract：:Some of trauma-exposed individuals develop posttraumatic stress disorder (PTSD), an incapacitating psychiatric disorder that is characterized by intrusion, avoidance, negative changes in mood and cognition, and hyperarousal. A number of other trauma-related conditions are very frequently found in individuals with PTSD...

journal_title：Neuropsychiatric disease and treatment

authors： Namgung E,Kim M,Yoon S

更新日期：2019-03-19 00:00:00

abstract：OBJECTIVE OF THE STUDY:To evaluate the value of serum creatine phosphokinase-brain specific (CK-BB) and urinary lactate/creatinine (L/C) ratio as early indicators of brain damage in full-term newborns with hypoxic ischemic encephalopathy (HIE). PATIENTS AND METHODS:A case-control study including 25 full-term new-born ...

journal_title：Neuropsychiatric disease and treatment

authors： Alkholy UM,Abdalmonem N,Zaki A,Ali YF,Mohamed SA,Abdelsalam NI,Hashim MIA,Sekkien MA,Elsherbiny YM

更新日期：2017-08-08 00:00:00

abstract：INTRODUCTION:Hemostasis is affected by interactions between physiological processes, including those connected with the coagulation system, whose essence is converting fibrinogen into fibrin. The role of factor VIII (FVIII) consists in activating factor X, which directly participates in the generation of thrombin, whic...

journal_title：Neuropsychiatric disease and treatment

authors： Lasek-Bal A,Puz P,Kazibutowska Z

更新日期：2013-01-01 00:00:00

abstract：:Night Eating Syndrome (NES) is a unique disorder characterized by a delayed pattern of food intake in which recurrent episodes of nocturnal eating and/or excessive food consumption occur after the evening meal. NES is a clinically important disorder due to its relationship to obesity, its association with other psychi...

journal_title：Neuropsychiatric disease and treatment

authors： Kucukgoncu S,Midura M,Tek C

更新日期：2015-03-19 00:00:00

abstract：BACKGROUND:In Japan, the effects of reduced water, such as hydrogen-rich electrolyzed reduced water and natural reduced water, like Hita Tenryosui water®, have been examined. The purpose of the present study was to identify the role of natural reduced water in anxiety and blood biochemical analysis. MATERIALS AND METH...

journal_title：Neuropsychiatric disease and treatment

authors： Masuda K,Tanaka Y,Kanehisa M,Ninomiya T,Inoue A,Higuma H,Kawashima C,Nakanishi M,Okamoto K,Akiyoshi J

更新日期：2017-09-08 00:00:00

abstract：BACKGROUND:We assessed the effect of switching patients with major depressive disorder to milnacipran following an initial selective serotonin reuptake inhibitor treatment failure, and explored potential biomarkers in their blood. METHODS:We conducted a prospective, open-label, 24-week trial. Depression was assessed w...

journal_title：Neuropsychiatric disease and treatment

authors： Hashimoto T,Sakurai D,Oda Y,Hasegawa T,Kanahara N,Sasaki T,Komatsu H,Takahashi J,Oiwa T,Sekine Y,Watanabe H,Iyo M

更新日期：2015-12-10 00:00:00

abstract：:At the time of this study, there were five known patients with Wilson disease (WD) in Iceland. The mutation, a 7-bp deletion in exon 7 on chromosome 13 for WD, is only known in Iceland. In twenty healthy Icelandic heterozygotes for WD and their age- and gender-matched controls, copper concentration in plasma, cerulopl...

journal_title：Neuropsychiatric disease and treatment

authors： Tórsdóttir G,Gudmundsson G,Kristinsson J,Snaedal J,Jóhannesson T

更新日期：2009-01-01 00:00:00

abstract：BACKGROUND:Repetitive transcranial magnetic stimulation (rTMS) of the dorsolateral prefrontal cortex (DLPFC) appears to have short-term antidepressant properties. The aim of the current study was to update our previous meta-analysis and to investigate factors associated with the antidepressant properties of rTMS. METH...

journal_title：Neuropsychiatric disease and treatment

authors： Kedzior KK,Azorina V,Reitz SK

更新日期：2014-05-07 00:00:00

abstract：:An 87-year-old woman had both Lewy body dementia and normal pressure hydrocephalus simultaneously. One should not automatically exclude the possibility of normal pressure hydrocephalus simply because another neurodegenerative disorder is present, especially if the second disorder masks typical symptoms of normal press...

journal_title：Neuropsychiatric disease and treatment

authors： Alisky J

更新日期：2008-02-01 00:00:00

abstract：Introduction:Sleep disturbance is a major health concern for heroin users receiving methadone maintenance treatment (MMT). The present study was aimed to investigate the predictors for new-onset clinically predominant sleep disturbance (CPSD) among heroin users receiving MMT. Methods:This 2-year retrospective study in...

journal_title：Neuropsychiatric disease and treatment

authors： Li DJ,Chung KS,Wu HC,Hsu CY,Yen CF

更新日期：2018-10-26 00:00:00

abstract：:It is proposed that lithium's therapeutic effects occur indirectly by augmenting a cascade of protective "fail-safe" pathways pre-configured to activate in response to a dangerous low cell [Mg++] situation, eg, posttraumatic brain injury, alongside relative cell adenosine triphosphate depletion. Lithium activates cell...

journal_title：Neuropsychiatric disease and treatment

authors： van Woerkom AE

更新日期：2017-01-31 00:00:00

abstract：Purpose:The study aimed to analyze the incidence of postoperative delirium (POD) and associated risk factors after liver transplantation (LT). Patients and Methods:We identified and enrolled patients undergoing LT at the Second Xiangya Hospital, Central South University between August 2018 and May 2019. We abstracted ...

journal_title：Neuropsychiatric disease and treatment

authors： Chen J,Wang H,He Z,Li T

更新日期：2020-07-03 00:00:00

abstract：OBJECTIVE:To examine how clinical and demographic patient baseline characteristics influence effectiveness of duloxetine versus selective serotonin reuptake inhibitor (SSRI) treatment, in real-world Japanese clinical settings of patients with major depressive disorder (MDD) and associated painful physical symptoms (PPS...

journal_title：Neuropsychiatric disease and treatment

authors： Kuga A,Tsuji T,Hayashi S,Fujikoshi S,Tokuoka H,Yoshikawa A,Escobar R,Tanaka K,Azekawa T

更新日期：2017-08-04 00:00:00

abstract：BACKGROUND:Encephalitis with antibodies against N-methyl-D-aspartate receptor (NMDA-R) is classified as an autoimmune disorder with psychotic symptoms, which are frequently dominant. However, it remains unclear how frequently NMDA-R antibodies lead to a condition that mimics psychosis and first-episode schizophrenia. I...

journal_title：Neuropsychiatric disease and treatment

authors： Masopust J,Andrýs C,Bažant J,Vyšata O,Kuca K,Vališ M

更新日期：2015-03-06 00:00:00

abstract：Purpose:Cardiovascular and metabolic adverse events are costly to treat, and their incidence is increased amongst people with schizophrenia, with different rates observed for second-generation antipsychotics. To inform treatment choice, this study sought to estimate the lifetime costs associated with antipsychotic choi...

journal_title：Neuropsychiatric disease and treatment

authors： Kearns B,Cooper K,Cantrell A,Thomas C

更新日期：2021-01-20 00:00:00

abstract：:The neurodevelopmental hypothesis of schizophrenia posits that schizophrenia is a psychopathological condition resulting from aberrations in neurodevelopmental processes caused by a combination of environmental and genetic factors which proceed long before the onset of clinical symptoms. Many studies discuss an immuno...

journal_title：Neuropsychiatric disease and treatment

authors： Mattei D,Schweibold R,Wolf SA

更新日期：2015-05-27 00:00:00

abstract：:Catatonia is a serious, common syndrome of motoric and behavioral dysfunction, which carries high morbidity and mortality. Electroconvulsive therapy (ECT) is the definitive treatment for catatonia, but access to ECT for the treatment of catatonia remains inappropriately limited. Catatonia is observable, detectable, an...

journal_title：Neuropsychiatric disease and treatment

authors： Lloyd JR,Silverman ER,Kugler JL,Cooper JJ

更新日期：2020-09-25 00:00:00

abstract：Background:Intentional methanol intoxication (IMI) is an emerging public health issue in Asian countries, but few data are available in the literature on underlying psychiatric comorbidities in these suicide attempters. Patients and methods:We conducted a retrospective chart review on patients with methanol intoxicati...

journal_title：Neuropsychiatric disease and treatment

authors： Yang WS,Yen TH,Juang YY,Lee SH,Wang BH,Lee CP

更新日期：2019-01-31 00:00:00

abstract：BACKGROUND:Burden on caregivers of children/adolescents with attention-deficit/hyperactivity disorder (ADHD) is multidimensional, but incompletely understood. OBJECTIVE:To analyze caregiver burden across the concepts of work, social/family life, and parental worry/stress, in relation to selected contributing factors. ...

journal_title：Neuropsychiatric disease and treatment

authors： Fridman M,Banaschewski T,Sikirica V,Quintero J,Erder MH,Chen KS

更新日期：2017-02-07 00:00:00

abstract：BACKGROUND:Depressive symptoms are significant and very common psychiatric complications in patients with Alzheimer's disease (AD), which can aggravate the decline in social function. However, changes in the functional connectivity (FC) of the brain in AD patients with depressive symptoms (D-AD) remain unclear. OBJECT...

journal_title：Neuropsychiatric disease and treatment

authors： Zhang J,Guo Z,Liu X,Jia X,Li J,Li Y,Lv D,Chen W

更新日期：2017-10-11 00:00:00

abstract：:Functional neurological disorder (FND), a condition at the intersection of neurology and psychiatry, is a common and disabling outpatient referral to neurology and neuropsychiatry clinics. In this perspective article, we focus on the motor spectrum of FND (mFND), including individuals with functional movement disorder...

journal_title：Neuropsychiatric disease and treatment

authors： Saxena A,Godena E,Maggio J,Perez DL

更新日期：2020-09-18 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Patients with Alzheimer's disease (AD) are frequently unaware of their cognitive symptoms and medical diagnosis. The term "anosognosia" is used to indicate a general lack of awareness of one's disease or disorder. The neural substrate underlying anosognosia in AD is unclear. Since anosognosia f...

journal_title：Neuropsychiatric disease and treatment

authors： Fujimoto H,Matsuoka T,Kato Y,Shibata K,Nakamura K,Yamada K,Narumoto J

更新日期：2017-07-05 00:00:00

abstract：Aim:Cardiovascular risk factors are also risk factors for cognitive impairment. They have cumulative effect in target organ damage. The precise correlation between cardiovascular risk factors and cognitive impairment, as well as assessing the extent to which they may affect cognitive functioning, is difficult to ascert...

journal_title：Neuropsychiatric disease and treatment

authors： Yaneva-Sirakova T,Traykov L,Petrova J,Gruev I,Vassilev D

更新日期：2017-12-05 00:00:00

abstract：BACKGROUND:Latest studies show that low-energy extracorporeal shock wave therapy (ESWT) can upregulate levels of vascular endothelial growth factor (VEGF). VEGF can ease nervous tissue harm after spinal cord injury (SCI). This study aims to explore whether low-energy ESWT can promote expression of VEGF, protect nervous...

journal_title：Neuropsychiatric disease and treatment

authors： Wang L,Jiang Y,Jiang Z,Han L

更新日期：2016-08-31 00:00:00