A fully integrated new paradigm for lithium's mode of action - lithium utilizes latent cellular fail-safe mechanisms.

abstract：:Traumatic brain injury (TBI) is a well recognized public health problem worldwide. TBI has previously been considered as a rare cause of hypopituitarism, but an increased prevalence of neuroendocrine dysfunction in patients with TBI has been reported during the last 15 years in most of the retrospective and prospectiv...

journal_title：Neuropsychiatric disease and treatment

authors： Tanriverdi F,Kelestimur F

更新日期：2015-07-27 00:00:00

abstract：:Melatonin (n-acetyl-5-methoxy-tryptamine), a naturally occurring indole produced mainly by the pineal gland, is a well known antioxidant. Stroke (cerebral ischemia) is the second leading cause of death worldwide. To date, however, effective and safe treatment for stroke remains unavailable. Melatonin is both lipid- an...

journal_title：Neuropsychiatric disease and treatment

authors： Lin HW,Lee EJ

更新日期：2009-01-01 00:00:00

abstract：PURPOSE:Major depressive disorder (MDD) is highly prevalent in patients with a chronic physical condition, and this comorbidity has a negative influence on quality of life, health care costs, self-care, morbidity, and mortality. Research has shown that collaborative care (CC) may be a cost-effective treatment. However,...

journal_title：Neuropsychiatric disease and treatment

authors： Goorden M,van der Feltz-Cornelis CM,van Steenbergen-Weijenburg KM,Horn EK,Beekman AT,Hakkaart-van Roijen L

更新日期：2017-07-18 00:00:00

abstract：Purpose:Whole-exome sequencing (WES) of multiplex families is a promising strategy for identifying causative variations for common diseases. To identify rare recessive risk variations for schizophrenia, we performed a WES study in a consanguineous family with affected siblings. We then performed follow-up sequencing of...

journal_title：Neuropsychiatric disease and treatment

authors： Igeta H,Watanabe Y,Morikawa R,Ikeda M,Otsuka I,Hoya S,Koizumi M,Egawa J,Hishimoto A,Iwata N,Someya T

更新日期：2019-08-19 00:00:00

abstract：Purpose:Typically, the diagnosis of conversion motor disorder (CMD) is achieved by the exclusion of a wide range of organic illnesses rather than by applying positive criteria. New diagnostic criteria are highly needed in this scenario. The main aim of this study was to explore the use of behavioral features as an incl...

journal_title：Neuropsychiatric disease and treatment

authors： Pastore A,Pierri G,Fabio G,Ferramosca S,Gigante A,Superbo M,Pellicciari R,Margari F

更新日期：2018-05-18 00:00:00

abstract：Purpose:To investigate the current clinical practice of Japanese physicians in the diagnosis and management of major depression (major depressive disorder [MDD]). Patients and methods:Japanese physicians specializing in psychiatry or psychosomatic medicine in the medical database of Nihon Ultmarc Inc. (Chuo-Ku, Tokyo,...

journal_title：Neuropsychiatric disease and treatment

authors： Hori H,Yamato K

更新日期：2019-10-01 00:00:00

abstract：:Studies on unmet needs during the last decades have played a significant role in the development and dissemination of evidence-based community practices for persistent schizophrenia and other severe mental disorders. This review has thoroughly considered several blocks of unmet needs, which are frequently related to s...

journal_title：Neuropsychiatric disease and treatment

authors： Torres-González F,Ibanez-Casas I,Saldivia S,Ballester D,Grandón P,Moreno-Küstner B,Xavier M,Gómez-Beneyto M

更新日期：2014-01-16 00:00:00

abstract：BACKGROUND:Anterior cingulate cortex (ACC) dysfunction is implicated in schizophrenia by numerous strands of scientific investigation. Functional neuroimaging studies of the ACC in schizophrenia have shown task-related hypo-activation, hyper-activation, and normal activation relative to comparison subjects. Interpretin...

journal_title：Neuropsychiatric disease and treatment

authors： Adams R,David AS

更新日期：2007-02-01 00:00:00

abstract：:Objective: Fibromyalgia syndrome (FMS) is a chronic disorder associated with severe pain. According to the National Fibromyalgia Association, the prevalence of FMS is between 3% and 6% in the general population, with about 90% of the patients being women. The primary goal of this study was to evaluate the relationship...

journal_title：Neuropsychiatric disease and treatment

authors： Amin OA,Abouzeid SM,Ali SA,Amin BA,Alswat KA

更新日期：2019-05-27 00:00:00

abstract：:This study evaluates the correlation between failure to develop spontaneous imitation and language skills in pervasive developmental disorders. Sixty-four children between the age of 3 and 8 years were assessed using the Autism Diagnostic Interview-Revised (ADI-R), the Childhood Autism Rating Scale (CARS), and the Aut...

journal_title：Neuropsychiatric disease and treatment

authors： De Giacomo A,Portoghese C,Martinelli D,Fanizza I,L'abate L,Margari L

更新日期：2009-01-01 00:00:00

abstract：:Traumatic brain injury (TBI) is widespread and leads to death and disability in millions of individuals around the world each year. Overall incidence and prevalence of TBI are likely to increase in absolute terms in the future. Tackling the problem of treating TBI successfully will require improvements in the understa...

journal_title：Neuropsychiatric disease and treatment

authors： Flanagan SR,Cantor JB,Ashman TA

更新日期：2008-10-01 00:00:00

abstract：PURPOSE:Radioelectric asymmetric brain stimulation technology with its treatment protocols has shown efficacy in various psychiatric disorders. The aim of this work was to highlight the mechanisms by which these positive effects are achieved. The current study was conducted to determine whether a single 500-millisecond...

journal_title：Neuropsychiatric disease and treatment

authors： Rinaldi S,Fontani V,Castagna A

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND:Diagnosis and treatment of mood disorders in youth are still problematic because in this age the clinical presentation is atypical, and the diagnostic tools and the therapies are the same as that used for the adults. Mood disorders are categorically divided into unipolar disorders (major depressive disorder ...

journal_title：Neuropsychiatric disease and treatment

authors： Presicci A,Lecce P,Ventura P,Margari F,Tafuri S,Margari L

更新日期：2010-09-07 00:00:00

abstract：Background:Road traffic crashes (RTCs) can cause serious and long-lasting consequences for drivers, both in terms of physical and mental health outcomes. Posttraumatic stress disorder (PTSD) is the most frequent mental disorder occurring after traumatic exposure. Ethiopian drivers experience RTCs more frequently than o...

journal_title：Neuropsychiatric disease and treatment

authors： Alenko A,Berhanu H,Abera Tareke A,Reta W,Bariso M,Mulat E,Kenenisa C,Debebe W,Tolesa K,Girma S

更新日期：2019-12-24 00:00:00

abstract：:Family history, which includes both common environmental and genetic effects, is associated with an increased risk for many neuropsychiatric diseases. Investigators have identified several disease-causing mutations for specific neuropsychiatric disorders that display Mendelian segregation. Such discoveries can lead to...

journal_title：Neuropsychiatric disease and treatment

authors： Keller MA,Gwinn K,Nash J,Horsford J,Zhang R,Rich SS,Corriveau RA

更新日期：2007-01-01 00:00:00

abstract：:Stem cells are self-renewing undifferentiated cells that give rise to multiple types of specialized cells of the body. In the adult, stem cells are multipotents and contribute to homeostasis of the tissues and regeneration after injury. Until recently, it was believed that the adult brain was devoid of stem cells, hen...

journal_title：Neuropsychiatric disease and treatment

authors： Taupin P

更新日期：2007-12-01 00:00:00

abstract：:The neurodevelopmental hypothesis of schizophrenia posits that schizophrenia is a psychopathological condition resulting from aberrations in neurodevelopmental processes caused by a combination of environmental and genetic factors which proceed long before the onset of clinical symptoms. Many studies discuss an immuno...

journal_title：Neuropsychiatric disease and treatment

authors： Mattei D,Schweibold R,Wolf SA

更新日期：2015-05-27 00:00:00

abstract：BACKGROUND:Mirtazapine, which is classified as a noradrenergic and specific serotonergic antidepressant, is widely prescribed for the treatment of major depressive disorder. The potential predictive factors of the efficacy of mirtazapine and the tolerability based on the incidence of oversedation and jitteriness/anxiet...

journal_title：Neuropsychiatric disease and treatment

authors： Tsutsumi T,Sugawara H,Ito R,Asano M,Shimizu S,Ishigooka J,Nishimura K

更新日期：2016-10-05 00:00:00

abstract：:Attention deficit hyperactivity disorder (ADHD) is a neurodevelopmental disorder that often persists in adulthood. It is defined by inattention and/or hyperactivity-impulsivity. ADHD is associated with many comorbidities, including eating disorders (EDs). In the last decade, studies have reported that ADHD is linked w...

journal_title：Neuropsychiatric disease and treatment

authors： Ptacek R,Stefano GB,Weissenberger S,Akotia D,Raboch J,Papezova H,Domkarova L,Stepankova T,Goetz M

更新日期：2016-03-03 00:00:00

abstract：Purpose:Although gender differences have been reported in various aspects of adult attention-deficit hyperactivity disorder (ADHD), such as prevalence, comorbidities, and social functioning, there have been few such studies conducted in Japan. Our research investigated gender differences in sociodemographic and clinica...

journal_title：Neuropsychiatric disease and treatment

authors： Hayashi W,Suzuki H,Saga N,Arai G,Igarashi R,Tokumasu T,Ota H,Yamada H,Takashio O,Iwanami A

更新日期：2019-12-04 00:00:00

abstract：Background:The phospholipase A2 Group 6 (PLA2G6, also known as PLA2, PARK14, and iPLA2) gene encodes a group VIA calcium-independent phospholipase A2. Genetic polymorphism of PLA2G6 has been indicated to be involved in conferring susceptibility for Parkinson's disease (PD), whereas conclusive results have not been obta...

journal_title：Neuropsychiatric disease and treatment

authors： Liu H,Yao Y,Liu H,Peng Y,Ren J,Wu X,Mao R,Zhao J,Zhu Y,Niu Z,Yang T,Sun X,Jiang P,Zhang C,Fang Y

更新日期：2020-07-23 00:00:00

abstract：Objective:Previous studies have demonstrated a potentially close relationship between mood disorders and thyroid abnormalities. The aims of this study are to investigate: 1) whether significant differences of thyroid profiles exist between manic and depressive episodes in patients with bipolar disorder (BD); 2) the imp...

journal_title：Neuropsychiatric disease and treatment

authors： Li C,Lai J,Huang T,Han Y,Du Y,Xu Y,Hu S

更新日期：2019-08-09 00:00:00

abstract：OBJECTIVES:Depressive symptoms are common among patients with obesity. Abnormalities in dopamine signaling involved in the reward circuit may ensue excessive consumption of food, resulting in obesity and leading to neuropsychiatric disorders such as depression. This study sought to investigate the association of polymo...

journal_title：Neuropsychiatric disease and treatment

authors： Bieliński M,Jaracz M,Lesiewska N,Tomaszewska M,Sikora M,Junik R,Kamińska A,Tretyn A,Borkowska A

更新日期：2017-08-18 00:00:00

abstract：BACKGROUND:Physical exercise has well-characterized positive effects on depressive symptoms. The underlying biologic mechanisms are, however, far from established. A recently discovered mechanism has linked the enhanced conversion of kynurenine to kynurenic acid (KYNA) to an increased resilience toward stress-induced d...

journal_title：Neuropsychiatric disease and treatment

authors： Millischer V,Erhardt S,Ekblom Ö,Forsell Y,Lavebratt C

更新日期：2017-03-31 00:00:00

abstract：:Olanzapine long-acting injection (OLAI) is a crystalline salt composed of olanzapine and pamoic acid, which permits a depot intramuscular formulation of olanzapine. The half-life of olanzapine pamoate is 30 days, and its steady state is reached approximately at 12 weeks. Oral supplementation of olanzapine is not requi...

journal_title：Neuropsychiatric disease and treatment

authors： Di Lorenzo R,Brogli A

更新日期：2010-09-07 00:00:00

abstract：:Anti-N-methyl-d-aspartate (anti-NMDA) receptor encephalitis is a newly recognized, potentially fatal, but treatable autoimmune disease. Good outcome predictors include milder severity of symptoms, no need for intensive care unit admission, early aggressive immunotherapy, and prompt tumor removal. We report a case of a...

journal_title：Neuropsychiatric disease and treatment

authors： Guo YH,Kuan TS,Hsieh PC,Lien WC,Chang CK,Lin YC

更新日期：2014-11-24 00:00:00

abstract：Background:Various clinical trials suggested that risperidone was beneficial in the treatment of autism spectrum disorder (ASD) in children and adolescents. Objective:The aim of this systematic review was to determine the efficacy, acceptability and tolerability of risperidone in the treatment of children and adolesce...

journal_title：Neuropsychiatric disease and treatment

authors： Maneeton N,Maneeton B,Putthisri S,Woottiluk P,Narkpongphun A,Srisurapanont M

更新日期：2018-07-11 00:00:00

abstract：:Epilepsy is a common pediatric neurologic disorder that is difficult to manage in a substantial portion of children. Levetiracetam (LEV) is a novel antiepileptic drug (AED) that has recently been approved as add-on treatment for various seizure types in epilepsy populations that include children: for refractory partia...

journal_title：Neuropsychiatric disease and treatment

authors： Wheless JW

更新日期：2007-08-01 00:00:00

abstract：:It has been well established that patients with schizophrenia have impairments in cognitive functioning and also that patients who experienced traumatic events suffer from cognitive deficits. Of the cognitive deficits revealed in schizophrenia or posttraumatic stress disorder (PTSD) patients, the current article provi...

journal_title：Neuropsychiatric disease and treatment

authors： Jung W,Lee SH

更新日期：2016-05-10 00:00:00

abstract：:Ekbom disease (EKD), formerly known as restless legs syndrome (RLS) has affected and bothered many people over the centuries. It is one of the most prevalent neurological disorders in Europe and North-America, affecting about 10% of the population. The main characteristics are the strong urge to move, accompanied or c...

journal_title：Neuropsychiatric disease and treatment

authors： Mitchell UH

更新日期：2011-01-01 00:00:00