Whole genome association studies of neuropsychiatric disease: An emerging era of collaborative genetic discovery.

abstract：:Night Eating Syndrome (NES) is a unique disorder characterized by a delayed pattern of food intake in which recurrent episodes of nocturnal eating and/or excessive food consumption occur after the evening meal. NES is a clinically important disorder due to its relationship to obesity, its association with other psychi...

journal_title：Neuropsychiatric disease and treatment

authors： Kucukgoncu S,Midura M,Tek C

更新日期：2015-03-19 00:00:00

abstract：OBJECTIVE:The Dark Triad (DT) describes a set of three closely related personality traits: Machiavellianism, narcissism, and psychopathy. Mental toughness (MT) refers to a psychological construct combining confidence, commitment, control, and challenge. High MT is related to greater physical activity (PA) and, relative...

journal_title：Neuropsychiatric disease and treatment

authors： Sabouri S,Gerber M,Sadeghi Bahmani D,Lemola S,Clough PJ,Kalak N,Shamsi M,Holsboer-Trachsler E,Brand S

更新日期：2016-01-27 00:00:00

abstract：CLINICAL QUESTION:What is the best current disease-modifying therapy for relapsing-remitting multiple sclerosis? RESULTS:The evidence shows that the most effective disease-modifying therapy for delaying short- to medium-term disability progression, prevention of relapses, reducing the area and activity of lesions on m...

journal_title：Neuropsychiatric disease and treatment

authors： González-Andrade F,Alcaraz-Alvarez JL

更新日期：2010-09-07 00:00:00

abstract：Objective:Impairments in emotion regulation, and more specifically in cognitive reappraisal, are thought to play a key role in the pathogenesis of anxiety disorders. However, the available evidence on such deficits is inconsistent. To further illustrate the neurobiological underpinnings of anxiety disorder, the present...

journal_title：Neuropsychiatric disease and treatment

authors： Wang HY,Zhang XX,Si CP,Xu Y,Liu Q,Bian HT,Zhang BW,Li XL,Yan ZR

更新日期：2018-05-09 00:00:00

abstract：:Transcranial magnetic stimulation is an increasingly popular FDA-approved treatment for resistant depression, migraines, and OCD. Research is also underway for its use in various other psychiatric and medical disorders. Although rare, seizures are a potential adverse event of TMS treatment. In this article, we discuss...

journal_title：Neuropsychiatric disease and treatment

authors： Stultz DJ,Osburn S,Burns T,Pawlowska-Wajswol S,Walton R

更新日期：2020-12-07 00:00:00

abstract：BACKGROUND:The main aim of this study was to assess the reliability and structural validity of the French version of the 12-item version of the Personal Report of Confidence as Speaker (PRCS), one of the most promising measurements of public speaking fear. METHODS:A total of 611 French-speaking volunteers were adminis...

journal_title：Neuropsychiatric disease and treatment

authors： Heeren A,Ceschi G,Valentiner DP,Dethier V,Philippot P

更新日期：2013-01-01 00:00:00

abstract：Purpose:Paliperidone extended release (ER) is an oral psychotropic treatment formulated to release paliperidone at a controlled, gradually ascending rate. We evaluated the efficacy and safety of switching to paliperidone ER in Taiwanese patients with schizophrenia who were unresponsive or intolerant to previous antipsy...

journal_title：Neuropsychiatric disease and treatment

authors： Chen CY,Tang TC,Chen TT,Bai YM,Tsai HH,Chen HL,Huang CJ,Chen CK,Chen CC,Hsiao MC,Liu CY,Yeh HS,Chiu NY,Hsiao CC,Chen CS,Su TP

更新日期：2018-03-08 00:00:00

abstract：BACKGROUND:Mirtazapine, which is classified as a noradrenergic and specific serotonergic antidepressant, is widely prescribed for the treatment of major depressive disorder. The potential predictive factors of the efficacy of mirtazapine and the tolerability based on the incidence of oversedation and jitteriness/anxiet...

journal_title：Neuropsychiatric disease and treatment

authors： Tsutsumi T,Sugawara H,Ito R,Asano M,Shimizu S,Ishigooka J,Nishimura K

更新日期：2016-10-05 00:00:00

abstract：:The relapse rate for many psychiatric disorders is staggeringly high, indicating that treatment methods combining psychotherapy with neuropharmacological interventions are not entirely effective. Therefore, in psychiatry, there is a current push to develop alternatives to psychotherapy and medication-based approaches....

journal_title：Neuropsychiatric disease and treatment

authors： Campanella S

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:Relapse is common in schizophrenia, and seriously impacts patients' quality of life and social functioning. Many factors have been identified that may potentially increase the risk of relapse. This study was designed to investigate the relapse rate in the year following hospital discharge among Chinese patie...

journal_title：Neuropsychiatric disease and treatment

authors： Xiao J,Mi W,Li L,Shi Y,Zhang H

更新日期：2015-05-08 00:00:00

abstract：:The pharmacodynamic properties of fluvoxamine maleate include the modulation of different populations of serotonergic, dopaminergic, and sigma receptors and/or transporters, a complex pattern of activity that may account for its efficacy in the treatment of obsessive-compulsive disorder (OCD). Nevertheless, its pharma...

journal_title：Neuropsychiatric disease and treatment

authors： Ordacgi L,Mendlowicz MV,Fontenelle LF

更新日期：2009-01-01 00:00:00

abstract：BACKGROUND:Articulation disorders in young children are due to defects occurring at a certain stage in sensory and motor development. Some children with functional articulation disorders may also have sensory integration dysfunction (SID). We hypothesized that speech therapy would be less efficacious in children with S...

journal_title：Neuropsychiatric disease and treatment

authors： Tung LC,Lin CK,Hsieh CL,Chen CC,Huang CT,Wang CH

更新日期：2013-01-01 00:00:00

abstract：:Neuropsychiatric symptoms are common in older adults with dementia and can be associated with a rapid decline in cognitive and functional status. This article reviews the current literature supporting the use of atypical antipsychotic medications in this population. Among the currently available atypical antipsychotic...

journal_title：Neuropsychiatric disease and treatment

authors： Lee PE,Gill SS,Rochon P

更新日期：2006-12-01 00:00:00

abstract：:Objective: Fibromyalgia syndrome (FMS) is a chronic disorder associated with severe pain. According to the National Fibromyalgia Association, the prevalence of FMS is between 3% and 6% in the general population, with about 90% of the patients being women. The primary goal of this study was to evaluate the relationship...

journal_title：Neuropsychiatric disease and treatment

authors： Amin OA,Abouzeid SM,Ali SA,Amin BA,Alswat KA

更新日期：2019-05-27 00:00:00

abstract：PURPOSE:Abnormalities in both cortisol and dehydroepiandrosterone (DHEA) have been reported in psychiatric disorders. Analysis of saliva, urine and blood cortisol and DHEA levels provides an index of hormone levels over a short time period. Unlike such conventional measures, fingernails incorporate endogenous hormones ...

journal_title：Neuropsychiatric disease and treatment

authors： Warnock F,McElwee K,Seo RJ,McIsaac S,Seim D,Ramirez-Aponte T,Macritchie KA,Young AH

更新日期：2010-02-03 00:00:00

abstract：PURPOSE:Akathisia remains a common side effect especially from antipsychotic medication. If the condition is diagnosed the management options are limited. SUBJECTS/METHODOLOGY: We tested a structured relaxation program on nine patients with a diagnosis of schizophrenia suffering from akathisia. All patients were rated ...

journal_title：Neuropsychiatric disease and treatment

authors： Hansen LK,L'allemand T,Thiry F,Baldwin DS

更新日期：2010-05-25 00:00:00

abstract：:Schizophrenia is a chronic syndrome involving different clinical dimensions, and causes significant disability with a negative impact on the quality of life of patients and their caregivers. Current guidelines for the treatment of schizophrenia focus on maximizing a patient's adaptive functioning and quality of life i...

journal_title：Neuropsychiatric disease and treatment

authors： Pietrini F,Albert U,Ballerini A,Calò P,Maina G,Pinna F,Vaggi M,Boggian I,Fontana M,Moro C,Carpiniello B

更新日期：2019-04-30 00:00:00

abstract：:Autistic spectrum disorder (ASD) is a neurodevelopmental disorder and has a high prevalence in children. Recently, mitochondrial oxidative stress has been proposed to be associated with ASD. Besides, SIRT1/PGC-1α signaling plays an important role in combating oxidative stress. In this study, we sought to determine the...

journal_title：Neuropsychiatric disease and treatment

authors： Bu X,Wu,Lu X,Yang L,Xu X,Wang J,Tang J

更新日期：2017-06-23 00:00:00

abstract：Purpose:Parkinson's disease (PD) is a common neurodegenerative movement disorder, but the pathogenesis remains elusive. This study was aimed to explore key genes and long noncoding RNAs (lncRNAs) associated with PD. Materials and methods:Three patients with PD and three normal controls were enrolled in the present stu...

journal_title：Neuropsychiatric disease and treatment

authors： Zhou Y,Gu C,Li J,Zhu L,Huang G,Dai J,Huang H

更新日期：2018-11-22 00:00:00

abstract：:Multiple Sclerosis (MS) is an inflammatory and neurodegenerative disease of the central nervous system, and both T and B cells are involved in its pathogenesis. The vast majority of disease-modifying drugs used for MS act on the inflammatory component of the disease and are approved for use in relapsing-remitting (RR)...

journal_title：Neuropsychiatric disease and treatment

authors： Frau J,Coghe G,Lorefice L,Fenu G,Cocco E

更新日期：2018-04-23 00:00:00

abstract：Objective:Stroke survivors generally have problems completing instrumental activities of daily living (IADL; eg, preparing meals, chores, taking a bath, and managing finances). However, it is unclear how stroke survivors might stave off IADL issues. Studies indicating that sleep has restorative neurological effects pro...

journal_title：Neuropsychiatric disease and treatment

authors： Seixas AA,Chung DP,Richards SL,Madhavaram S,Raghavan P,Gago J,Casimir G,Jean-Louis G

更新日期：2019-01-04 00:00:00

abstract：:During treatment of acute-phase schizophrenia, attention needs to be given to physical as well as psychological symptoms. It is often difficult, however, to obtain information on physical symptoms from patients with psychomotor excitation, and only laboratory examinations can provide objective data. The results of lab...

journal_title：Neuropsychiatric disease and treatment

authors： Nagamine T

更新日期：2010-06-24 00:00:00

abstract：BACKGROUND:Burden on caregivers of children/adolescents with attention-deficit/hyperactivity disorder (ADHD) is multidimensional, but incompletely understood. OBJECTIVE:To analyze caregiver burden across the concepts of work, social/family life, and parental worry/stress, in relation to selected contributing factors. ...

journal_title：Neuropsychiatric disease and treatment

authors： Fridman M,Banaschewski T,Sikirica V,Quintero J,Erder MH,Chen KS

更新日期：2017-02-07 00:00:00

abstract：:Orthostatic hypotension (OH) is a common condition, particularly in patients with α-synucleinopathies such as Parkinson's disease, and has a significant impact on activities of daily living and quality of life. Recent data suggest an association with cognitive impairment. Herein, we review the evidence that OH increas...

journal_title：Neuropsychiatric disease and treatment

authors： Robertson AD,Udow SJ,Espay AJ,Merola A,Camicioli R,Lang AE,Masellis M

更新日期：2019-08-02 00:00:00

abstract：BACKGROUND:Decreased relapse rate and slower disease progression have been reported with long-term use of immunomodulatory treatments (IMTs, interferon beta or glatiramer acetate) in relapsing-remitting multiple sclerosis. There are, however, patients who do not respond to such treatments, and they can be potential can...

journal_title：Neuropsychiatric disease and treatment

authors： Mezei Z,Bereczki D,Racz L,Csiba L,Csepany T

更新日期：2012-01-01 00:00:00

abstract：Purpose:Although there are highly precise and advanced diagnostic methods, the etiology and pathophysiology of schizophrenia remain poorly understood. There are several theories about schizophrenia origin, among which the neurodevelopmental theory is widely accepted. Our study aimed to assess minor physical anomalies a...

journal_title：Neuropsychiatric disease and treatment

authors： Tsehay B,Shitie D

更新日期：2020-10-28 00:00:00

abstract：:Delirium occurs in 23% of sepsis patients, in which pro-inflammatory cytokines and nitric oxide are suggested to be involved. However, in animal experiments, even a subseptic dose of lipopolysaccharide (LPS) injection induces both pro-inflammatory cytokines and inducible nitric oxide synthase in the brain, suggesting ...

journal_title：Neuropsychiatric disease and treatment

authors： Maeda S,Nakatsuka I,Hayashi Y,Higuchi H,Shimada M,Miyawaki T

更新日期：2008-06-01 00:00:00

abstract：BACKGROUND:Shen-Qi-Jie-Yu-Fang (SJF) is composed of eight Chinese medicinal herbs. It is widely used in traditional Chinese medicine for treating postpartum depression (PPD). Previous studies have shown that SJF treats PPD through the neuroendocrine mechanism. AIM:To further investigate the effect of SJF on the immune...

journal_title：Neuropsychiatric disease and treatment

authors： Li J,Zhao R,Li X,Sun W,Qu M,Tang Q,Yang X,Zhang S

更新日期：2016-04-15 00:00:00

abstract：OBJECTIVE:This study provides insight into the thoughts and opinions of geriatric health-care professionals toward cognitive assessments and the use of emerging technologies, such as eye-tracking, to supplement current tools. METHODS:Two focus group sessions were conducted with nurses and physicians who routinely admi...

journal_title：Neuropsychiatric disease and treatment

authors： Whitehead JC,Gambino SA,Richter JD,Ryan JD

更新日期：2015-06-12 00:00:00

abstract：OBJECTIVE:We aimed to assess psychiatric morbidities of patients with head and neck cancer (HNC) in a prospective study at pretreatment, and 3 and 6 months after treatment, and to compare their health-related quality of life (HRQL) between those with and without depressive disorders (depression). MATERIALS AND METHODS...

journal_title：Neuropsychiatric disease and treatment

authors： Wu YS,Lin PY,Chien CY,Fang FM,Chiu NM,Hung CF,Lee Y,Chong MY

更新日期：2016-04-27 00:00:00