MiRNA-532-5p Regulates CUMS-Induced Depression-Like Behaviors and Modulates LPS-Induced Proinflammatory Cytokine Signaling by Targeting STAT3.

abstract：BACKGROUND:Epidemiology continues to be an important research tool in the study of epilepsy and related disorders, providing a better understanding of the frequency, causes, and natural history of the disorder. OBJECTIVE:To estimate the prevalence of epilepsy in Al-Quseir, Red Sea Governorate, Egypt, and its magnitude...

journal_title：Neuropsychiatric disease and treatment

authors： El-Tallawy HN,Farghaly WM,Rageh TA,Shehata GA,Metwally NA,Badry R,Sayed MA,Abdelwarith AM,Kandil MR,Hamed MA,Mohamed KO,Tohamy AM

更新日期：2016-05-12 00:00:00

abstract：:Pregabalin is a new antiepileptic medication that works by binding to alpha 2 delta subunit of the voltage-dependent calcium channels present in presynaptic neurons. Its pharmacokinetic advantages include rapid and almost complete absorption, lack of protein binding, linear kinetics, absence of enzyme induction, and a...

journal_title：Neuropsychiatric disease and treatment

authors： Arain AM

更新日期：2009-01-01 00:00:00

abstract：OBJECTIVE:To investigate the predictors of suicidal ideation and attempts among Turkish Parkinson's disease (PD) patients. MATERIALS AND METHODS:The study comprised 120 patients with PD. Clinical findings were obtained by using the Unified Parkinson's Disease Rating Scale. Disease severity was measured by the Hoehn an...

journal_title：Neuropsychiatric disease and treatment

authors： Ozdilek B,Gultekin BK

更新日期：2014-03-26 00:00:00

abstract：Objective:To investigate the relationship between Hamilton Depression Rating Scale (HAM-D) score and psychiatrists' judgment of working ability in patients with major depressive disorder (MDD) and painful physical symptoms. Methods:This was a prospective, observational, 12-week study in patients who received duloxetin...

journal_title：Neuropsychiatric disease and treatment

authors： Kuga A,Otsubo T,Tsuji T,Hayashi S,Imagawa H,Fujikoshi S,Escobar R

更新日期：2019-04-05 00:00:00

abstract：:Night Eating Syndrome (NES) is a unique disorder characterized by a delayed pattern of food intake in which recurrent episodes of nocturnal eating and/or excessive food consumption occur after the evening meal. NES is a clinically important disorder due to its relationship to obesity, its association with other psychi...

journal_title：Neuropsychiatric disease and treatment

authors： Kucukgoncu S,Midura M,Tek C

更新日期：2015-03-19 00:00:00

abstract：:The essential features of bipolar affective disorder involve the cyclical occurrence of high (manic or hypomanic episodes) and low mood states. Depressive episodes in both bipolar I and II disorder are more numerous and last for longer duration than either manic or hypomanic episodes. In addition depressive episodes a...

journal_title：Neuropsychiatric disease and treatment

authors： Gajwani P,Muzina DJ,Kemp DE,Gao K,Calabrese JR

更新日期：2007-12-01 00:00:00

abstract：OBJECTIVE:To study clinical correlates of religiosity in Parkinson's disease (PD). METHODS:Measures of life goals, religiosity, mood, and neuropsychologic function were assessed in 22 persons with mid-stage PD and 20 age-matched healthy controls. Levodopa dose equivalents (LDE) were also computed for the patients. RE...

journal_title：Neuropsychiatric disease and treatment

authors： McNamara P,Durso R,Brown A

更新日期：2006-09-01 00:00:00

abstract：BACKGROUND:There have not been any reports in Japan clarifying the efficacy and safety of intramuscular (IM) olanzapine and IM levomepromazine in agitated elderly patients with schizophrenia. This study was a comparative investigation of the clinical efficacy and safety of IM olanzapine and IM levomepromazine in agitat...

journal_title：Neuropsychiatric disease and treatment

authors： Suzuki H,Gen K

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:This study aims to verify the main psychometric properties of the Italian version of the Impact of Event Scale - Revised (IES-R) in a sample of flood victims. METHODS:The sample was composed of 262 subjects involved in the natural disaster of 2009 in the city of Messina (Italy). All participants completed t...

journal_title：Neuropsychiatric disease and treatment

authors： Craparo G,Faraci P,Rotondo G,Gori A

更新日期：2013-01-01 00:00:00

abstract：Purpose:Entropy analysis of resting-state functional magnetic resonance imaging (R-fMRI) has recently been adopted to characterize brain temporal dynamics in some neuropsychological or psychiatric diseases. Thalamus-related dysfunction might be a potential trait marker of major depressive disorder (MDD), but the abnorm...

journal_title：Neuropsychiatric disease and treatment

authors： Xue SW,Wang D,Tan Z,Wang Y,Lian Z,Sun Y,Hu X,Wang X,Zhou X

更新日期：2019-09-11 00:00:00

abstract：Purpose:Parkinson's disease (PD) is a common neurodegenerative movement disorder, but the pathogenesis remains elusive. This study was aimed to explore key genes and long noncoding RNAs (lncRNAs) associated with PD. Materials and methods:Three patients with PD and three normal controls were enrolled in the present stu...

journal_title：Neuropsychiatric disease and treatment

authors： Zhou Y,Gu C,Li J,Zhu L,Huang G,Dai J,Huang H

更新日期：2018-11-22 00:00:00

abstract：BACKGROUND:Previous studies have demonstrated that long noncoding RNA cancer susceptibility candidate 2 (lncRNA CASC2) is frequently downregulated in several types of tumors and functions as a tumor-suppressive factor. However, the clinical significance and function of CASC2 in human glioma remain largely unknown. The ...

journal_title：Neuropsychiatric disease and treatment

authors： Wang R,Li Y,Zhu G,Tian B,Zeng W,Yang Y,Li Z

更新日期：2017-07-11 00:00:00

abstract：OBJECTIVE:We aimed to assess psychiatric morbidities of patients with head and neck cancer (HNC) in a prospective study at pretreatment, and 3 and 6 months after treatment, and to compare their health-related quality of life (HRQL) between those with and without depressive disorders (depression). MATERIALS AND METHODS...

journal_title：Neuropsychiatric disease and treatment

authors： Wu YS,Lin PY,Chien CY,Fang FM,Chiu NM,Hung CF,Lee Y,Chong MY

更新日期：2016-04-27 00:00:00

abstract：:Family history, which includes both common environmental and genetic effects, is associated with an increased risk for many neuropsychiatric diseases. Investigators have identified several disease-causing mutations for specific neuropsychiatric disorders that display Mendelian segregation. Such discoveries can lead to...

journal_title：Neuropsychiatric disease and treatment

authors： Keller MA,Gwinn K,Nash J,Horsford J,Zhang R,Rich SS,Corriveau RA

更新日期：2007-01-01 00:00:00

abstract：Objective:Our study aimed to estimate the frequency of inborn errors of metabolism (IEMs) in patients presenting with acute encephalopathy-like picture at an emergency department (ED). Subjects and methods:Our study was a prospective observational study conducted on 30 patients admitted to the pediatric ED with unexpl...

journal_title：Neuropsychiatric disease and treatment

authors： Abdel Maksoud M,ELsayed SM,Shatla RH,Imam AA,Elsayed RM,Mosabah AA,Sherif AM

更新日期：2018-06-29 00:00:00

abstract：:Obsessive-compulsive disorder (OCD) is a chronic anxiety disorder. While medication and psychotherapy advances have been very helpful to patients, many patients do not respond adequately to initial trials of serotonergic medication or cognitive-behavioral therapy (CBT) and require multiple treatment trials or combinat...

journal_title：Neuropsychiatric disease and treatment

authors： Walsh KH,McDougle CJ

更新日期：2011-01-01 00:00:00

abstract：:Lacosamide is a newly registered antiepileptic drug with dual mechanisms of action. It selectively enhances slow inactivation of voltage-gated sodium channels, resulting in stabilization of hyperexcitable neuronal membranes and inhibition of repetitive neuronal firing. It also binds to a collapsing-response mediator p...

journal_title：Neuropsychiatric disease and treatment

authors： Kelemen A,Halász P

更新日期：2010-09-07 00:00:00

abstract：:Melatonin (n-acetyl-5-methoxy-tryptamine), a naturally occurring indole produced mainly by the pineal gland, is a well known antioxidant. Stroke (cerebral ischemia) is the second leading cause of death worldwide. To date, however, effective and safe treatment for stroke remains unavailable. Melatonin is both lipid- an...

journal_title：Neuropsychiatric disease and treatment

authors： Lin HW,Lee EJ

更新日期：2009-01-01 00:00:00

abstract：BACKGROUND:The body dysmorphic disorder is prevalent in general population and in psychiatric, dermatological, and plastic-surgery patients, but there lacks a structure-validated, comprehensive self-report measure of body image concerns, which is established through both exploratory and confirmatory factor analyses. M...

journal_title：Neuropsychiatric disease and treatment

authors： He W,Zheng Q,Ji Y,Shen C,Zhu Q,Wang W

更新日期：2017-05-29 00:00:00

abstract：Purpose:Dual diagnosis (DD) is the co-occurrence of both a mental illness and a substance use disorder (SUD). Lots of studies have analysed the integrated clinical approach, which involves both psychiatry and toxicology medical experts. The purpose of this study is to analyse the socio-demographic characteristics and t...

journal_title：Neuropsychiatric disease and treatment

authors： Milano G,Vergani HM,Cattedra S,Carrozzino R,Mattioli F,Robbiano L,Martelli A

更新日期：2019-12-18 00:00:00

abstract：PURPOSE:The aim of the study reported here was to examine the safety and effectiveness of high-frequency repetitive transcranial magnetic stimulation (rTMS) in elderly patients with depression. PATIENTS AND METHODS:Sixty-five depressed elderly patients received rTMS over their left prefrontal cortex for 6 days per wee...

journal_title：Neuropsychiatric disease and treatment

authors： Hizli Sayar G,Ozten E,Tan O,Tarhan N

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:The manifestation of attention-deficit/hyperactivity disorder (ADHD) among older adults has become an interesting topic of interest due to an increasing number of adults aged 50 years and older (≥50 years) seeking assessment for ADHD. Unfortunately, there is a lack of research on ADHD in older adults, and un...

journal_title：Neuropsychiatric disease and treatment

authors： Torgersen T,Gjervan B,Lensing MB,Rasmussen K

更新日期：2016-01-08 00:00:00

abstract：:Gerstmann's syndrome encompasses the tetrad of finger agnosia, agraphia, acalculia, and right-left confusion. An elderly man with a history of several cardiovascular diseases was initially brought to the psychiatric outpatient department by his family because of worsening of recent memory, executive function, and mixe...

journal_title：Neuropsychiatric disease and treatment

authors： Chen TY,Chen CY,Yen CH,Kuo SC,Yeh YW,Chang S,Huang SY

更新日期：2013-01-01 00:00:00

abstract：Background:Mental disorders affect about one-third of the human population, are typically chronic and significantly decrease the quality of life. Presently, the treatment of mental illnesses is far from adequate with a substantial proportion of the patients being pharmacoresistant and suffering from relapses. One of t...

journal_title：Neuropsychiatric disease and treatment

authors： Latalova K,Sery O,Hosakova K,Hosak L

更新日期：2020-05-06 00:00:00

abstract：Background:Road traffic crashes (RTCs) can cause serious and long-lasting consequences for drivers, both in terms of physical and mental health outcomes. Posttraumatic stress disorder (PTSD) is the most frequent mental disorder occurring after traumatic exposure. Ethiopian drivers experience RTCs more frequently than o...

journal_title：Neuropsychiatric disease and treatment

authors： Alenko A,Berhanu H,Abera Tareke A,Reta W,Bariso M,Mulat E,Kenenisa C,Debebe W,Tolesa K,Girma S

更新日期：2019-12-24 00:00:00

abstract：BACKGROUND:Following the approval of lisdexamfetamine dimesylate (LDX) in several European countries for the treatment of attention-deficit/hyperactivity disorder (ADHD) in children and adolescents with an inadequate response to methylphenidate (MPH) treatment, the aim of the present analysis was to establish the respo...

journal_title：Neuropsychiatric disease and treatment

authors： Coghill DR,Banaschewski T,Lecendreux M,Soutullo C,Zuddas A,Adeyi B,Sorooshian S

更新日期：2014-10-29 00:00:00

abstract：:This case report describes the detection of homonymous hemianopsia and delirium during the admission physical examination of a patient with esophageal adenocarcinoma, resulting in the new diagnosis of subacute hemorrhagic stroke. The poststroke visual field defect can result in significant disability and reduction in ...

journal_title：Neuropsychiatric disease and treatment

authors： Tsymbalov KS,Fetkenhour DR

更新日期：2016-06-15 00:00:00

abstract：Purpose:This study compared predictors of passive suicidal ideation (SI), active SI, and suicide attempt (SA) among elderly Thai patients in tertiary care settings. Patients and Methods:Psychiatric diagnoses and suicidality of 803 older people were assessed using the Mini-International Neuropsychiatric Interview and t...

journal_title：Neuropsychiatric disease and treatment

authors： Booniam S,Wongpakaran T,Lerttrakarnnon P,Jiraniramai S,Kuntawong P,Wongpakaran N

更新日期：2020-12-17 00:00:00

abstract：BACKGROUND:Physical exercise has well-characterized positive effects on depressive symptoms. The underlying biologic mechanisms are, however, far from established. A recently discovered mechanism has linked the enhanced conversion of kynurenine to kynurenic acid (KYNA) to an increased resilience toward stress-induced d...

journal_title：Neuropsychiatric disease and treatment

authors： Millischer V,Erhardt S,Ekblom Ö,Forsell Y,Lavebratt C

更新日期：2017-03-31 00:00:00

abstract：:Objective: Fibromyalgia syndrome (FMS) is a chronic disorder associated with severe pain. According to the National Fibromyalgia Association, the prevalence of FMS is between 3% and 6% in the general population, with about 90% of the patients being women. The primary goal of this study was to evaluate the relationship...

journal_title：Neuropsychiatric disease and treatment

authors： Amin OA,Abouzeid SM,Ali SA,Amin BA,Alswat KA

更新日期：2019-05-27 00:00:00