Towards Horizon 2020: challenges and advances for clinical mental health research - outcome of an expert survey.

abstract：:Gabapentin enacarbil is a prodrug of the anticonvulsant gabapentin. The efficacy and safety of gabapentin enacarbil for the treatment of moderate to severe primary restless legs syndrome (RLS) has been evaluated in several clinical trials in the United States and Japan. Although most clinical trials assessed gabapenti...

journal_title：Neuropsychiatric disease and treatment

authors： Kume A

更新日期：2014-02-03 00:00:00

abstract：INTRODUCTION:Antipsychotics are recommended as first-line therapy for acute mania and maintenance treatment of bipolar disorder; however, published literature suggests their real-world use remains limited. Understanding attitudes toward these medications may help identify barriers and inform personalized therapy. This ...

journal_title：Neuropsychiatric disease and treatment

authors： Sajatovic M,DiBiasi F,Legacy SN

更新日期：2017-08-30 00:00:00

abstract：:Few data are available on the applicability of both the criteria proposed by Silberstein and Lipton (S-L) and the International Classification of Headache Disorders-II (ICHD-II) in the classification of children and adolescents with chronic daily headache (CDH). The International Headache Society recently added revise...

journal_title：Neuropsychiatric disease and treatment

authors： Cuvellier JC,Couttenier F,Auvin S,Vallée L

更新日期：2008-02-01 00:00:00

abstract：Background:Based on inconsistent sensory alterations demonstrated in cluster headache (CH), the aim of this study was to determine whether patients with CH develop sensory changes in the symptomatic side compared to the asymptomatic side. Methods:Quantitative sensory testing (QST), including pressure pain threshold (P...

journal_title：Neuropsychiatric disease and treatment

authors： Malo-Urriés M,Hidalgo-García C,Estébanez-de-Miguel E,Tricás-Moreno JM,Santos-Lasaosa S,Jahanshahi M

更新日期：2018-12-10 00:00:00

abstract：BACKGROUND:Patients with schizophrenia show disturbances in both visual perception and social cognition. Perception of biological motion (BM) is a higher-level visual process, and is known to be associated with social cognition. BM induces activation in the "social brain network", including the superior temporal sulcus...

journal_title：Neuropsychiatric disease and treatment

authors： Hashimoto N,Toyomaki A,Hirai M,Miyamoto T,Narita H,Okubo R,Kusumi I

更新日期：2014-11-17 00:00:00

abstract：:Ischemic stroke is one of the leading causes of brain disease, with high morbidity, disability, and mortality. MicroRNAs (miRNAs) have been identified as vital gene regulators in various types of human diseases. Accumulating evidence has suggested that aberrant expression of miRNAs play critical roles in the pathologi...

journal_title：Neuropsychiatric disease and treatment

authors： Yao S,Tang B,Li G,Fan R,Cao F

更新日期：2016-12-05 00:00:00

abstract：:Major depressive disorder (MDD) and Parkinson's disease (PD) share symptoms such as tremor. Bupropion, a norepinephrine-dopamine reuptake inhibitor, shows weak dopamine transporter (DAT) occupancy. We report here on a patient with MDD whose hand tremors might have been misdiagnosed as PD by single-photon emission comp...

journal_title：Neuropsychiatric disease and treatment

authors： Lin CH,Lane HY

更新日期：2017-10-19 00:00:00

abstract：:Mycophenolate mofetil (MMF) has been used to treat myasthenia gravis (MG) for over 10 years. MMF's use in the MG population stems from its theoretical mechanism of action and the medical literature that supports its benefit in MG patients. Recently, two large, double-blinded, placebo-controlled, randomized clinical tr...

journal_title：Neuropsychiatric disease and treatment

authors： Heatwole C,Ciafaloni E

更新日期：2008-12-01 00:00:00

abstract：:In the present study, we investigated the relationship between physical activity (PA) and self-esteem (SE), while introducing body mass index (BMI), perceived physical fitness (PPF), and body image (BI) in adults (N =264, M =38.10 years). The findings indicated that PA was directly and indirectly associated with SE. B...

journal_title：Neuropsychiatric disease and treatment

authors： Zamani Sani SH,Fathirezaie Z,Brand S,Pühse U,Holsboer-Trachsler E,Gerber M,Talepasand S

更新日期：2016-10-12 00:00:00

abstract：:Functional neurological disorder (FND), a condition at the intersection of neurology and psychiatry, is a common and disabling outpatient referral to neurology and neuropsychiatry clinics. In this perspective article, we focus on the motor spectrum of FND (mFND), including individuals with functional movement disorder...

journal_title：Neuropsychiatric disease and treatment

authors： Saxena A,Godena E,Maggio J,Perez DL

更新日期：2020-09-18 00:00:00

abstract：:Prior studies have demonstrated the importance of treatment persistence with anti-psychotic agents in sustaining control of schizophrenic symptoms. However, the conventional approach in measuring treatment persistence tended to use only the first prescription episode even though some patients received multiple prescri...

journal_title：Neuropsychiatric disease and treatment

authors： Ren XS,Qian S,Kazis LE

更新日期：2007-04-01 00:00:00

abstract：BACKGROUND:Physical exercise has well-characterized positive effects on depressive symptoms. The underlying biologic mechanisms are, however, far from established. A recently discovered mechanism has linked the enhanced conversion of kynurenine to kynurenic acid (KYNA) to an increased resilience toward stress-induced d...

journal_title：Neuropsychiatric disease and treatment

authors： Millischer V,Erhardt S,Ekblom Ö,Forsell Y,Lavebratt C

更新日期：2017-03-31 00:00:00

abstract：BACKGROUND:We assessed the effect of switching patients with major depressive disorder to milnacipran following an initial selective serotonin reuptake inhibitor treatment failure, and explored potential biomarkers in their blood. METHODS:We conducted a prospective, open-label, 24-week trial. Depression was assessed w...

journal_title：Neuropsychiatric disease and treatment

authors： Hashimoto T,Sakurai D,Oda Y,Hasegawa T,Kanahara N,Sasaki T,Komatsu H,Takahashi J,Oiwa T,Sekine Y,Watanabe H,Iyo M

更新日期：2015-12-10 00:00:00

abstract：:Recent findings in animal models of paraplegia suggest that specific nonbenzodiazepine anxiolytics may temporarily restore locomotor functions after spinal cord injury (SCI). Experiments using in vitro models have revealed, indeed, that selective serotonin receptor (5-HTR) ligands such as 5-HTR(1A) agonists, known as ...

journal_title：Neuropsychiatric disease and treatment

authors： Guertin PA

更新日期：2008-08-01 00:00:00

abstract：:Objective: Fibromyalgia syndrome (FMS) is a chronic disorder associated with severe pain. According to the National Fibromyalgia Association, the prevalence of FMS is between 3% and 6% in the general population, with about 90% of the patients being women. The primary goal of this study was to evaluate the relationship...

journal_title：Neuropsychiatric disease and treatment

authors： Amin OA,Abouzeid SM,Ali SA,Amin BA,Alswat KA

更新日期：2019-05-27 00:00:00

abstract：Introduction:The study was designed to explore the possible adverse effects of prenatal polycyclic aromatic hydrocarbons (PAHs) on the neurodevelopment of the infants at the age of 12 months in a birth cohort in Qingdao of China. Benzo[a]pyrene (BaP)-DNA adduct level in umbilical cord blood was measured by enzyme immun...

journal_title：Neuropsychiatric disease and treatment

authors： Zhang Y,Yang Y,Zhang Q,Cui J,Rahaman A,Huang XR,Su Y,Gao R,Wang B,Baloch Z

更新日期：2019-12-02 00:00:00

abstract：:Diagnosis of complex partial epilepsy is based on the clinical history, and laboratory tests, including EEG and neuroimaging studies, corroborate the diagnosis. The goal of epilepsy management is to make the patient completely seizure-free without drug-induced side effects, even in the patient with refractory complex ...

journal_title：Neuropsychiatric disease and treatment

authors： Treiman DM

更新日期：2010-06-24 00:00:00

abstract：Aim:This meta-analysis aimed to assess the effect of high-frequency repetitive transcranial magnetic stimulation (HF-rTMS) for the treatment of depression in patients with Parkinson's disease (PD). Methods:The design was a meta-analysis of randomized controlled trials (RCTs). The participants were patients with PD who...

journal_title：Neuropsychiatric disease and treatment

authors： Qin B,Chen H,Gao W,Zhao LB,Zhao MJ,Qin HX,Yang MX

更新日期：2018-01-11 00:00:00

abstract：:Autism spectrum disorder (ASD) is a common neurodevelopmental disorder characterized by pervasive difficulties since early childhood across reciprocal social communication and restricted, repetitive interests and behaviors. Although early ASD research focused primarily on children, there is increasing recognition that...

journal_title：Neuropsychiatric disease and treatment

authors： Murphy CM,Wilson CE,Robertson DM,Ecker C,Daly EM,Hammond N,Galanopoulos A,Dud I,Murphy DG,McAlonan GM

更新日期：2016-07-07 00:00:00

abstract：:Traumatic brain injury (TBI) is a well recognized public health problem worldwide. TBI has previously been considered as a rare cause of hypopituitarism, but an increased prevalence of neuroendocrine dysfunction in patients with TBI has been reported during the last 15 years in most of the retrospective and prospectiv...

journal_title：Neuropsychiatric disease and treatment

authors： Tanriverdi F,Kelestimur F

更新日期：2015-07-27 00:00:00

abstract：BACKGROUND:This study aims to verify the main psychometric properties of the Italian version of the Impact of Event Scale - Revised (IES-R) in a sample of flood victims. METHODS:The sample was composed of 262 subjects involved in the natural disaster of 2009 in the city of Messina (Italy). All participants completed t...

journal_title：Neuropsychiatric disease and treatment

authors： Craparo G,Faraci P,Rotondo G,Gori A

更新日期：2013-01-01 00:00:00

abstract：OBJECTIVE:The study aimed at exploring bereavement and complicated grief (CG) symptoms among subjects without a history of coronary heart disease (CHD) at the time of a first acute coronary syndrome (ACS) and to evaluate the relationship of CG symptoms and ACS. METHOD:Overall, 149 subjects with ACS (namely, acute myoc...

journal_title：Neuropsychiatric disease and treatment

authors： Pini S,Gesi C,Abelli M,Cardini A,Lari L,Felice F,Di Stefano R,Mazzotta G,Bovenzi F,Bertoli D,Borelli L,Michi P,Oligeri C,Balbarini A,Manicavasagar V

更新日期：2015-10-07 00:00:00

abstract：BACKGROUND:Stroke has high mortality and morbidity. Biomarkers are required for to predict stroke outcomes, which could help clinicians to provide rationale approaches for patient management. The dynamic changes in circulating immune cells have been reported in stroke patients and animal models of stroke. AIM:The aim ...

journal_title：Neuropsychiatric disease and treatment

authors： Wang Y,Liu J,Wang X,Liu Z,Li F,Chen F,Geng X,Ji Z,Du H,Hu X

更新日期：2017-10-03 00:00:00

abstract：Background:Suicidal ideation (SI) is a cardinal aspect of major depressive disorder (MDD); however, patient-reported outcomes data from large-scale surveys are limited concerning SI in the context of MDD. This study aims to understand the association between varying levels of SI and health-related quality of life (HRQo...

journal_title：Neuropsychiatric disease and treatment

authors： Benson C,Singer D,Carpinella CM,Shawi M,Alphs L

更新日期：2021-01-18 00:00:00

abstract：Purpose:Although gender differences have been reported in various aspects of adult attention-deficit hyperactivity disorder (ADHD), such as prevalence, comorbidities, and social functioning, there have been few such studies conducted in Japan. Our research investigated gender differences in sociodemographic and clinica...

journal_title：Neuropsychiatric disease and treatment

authors： Hayashi W,Suzuki H,Saga N,Arai G,Igarashi R,Tokumasu T,Ota H,Yamada H,Takashio O,Iwanami A

更新日期：2019-12-04 00:00:00

abstract：:The cerebral cortex of the human brain has a complex morphological structure consisting of folded or smooth cortical surfaces. These morphological features are referred to as cortical gyrification and are characterized by the gyrification index (GI). A number of cortical gyrification studies have been published using ...

journal_title：Neuropsychiatric disease and treatment

authors： Matsuda Y,Ohi K

更新日期：2018-07-19 00:00:00

abstract：Purpose:This study aims to evaluate the quality of the Finnish clinical practice guideline related to schizophrenia care and how it can be utilized in psychiatric services. Participants and methods:The data were collected from one psychiatric ward and seven psychiatric outpatient units situated in two cities in Southe...

journal_title：Neuropsychiatric disease and treatment

authors： Vähäniemi A,Välimäki M,Pekurinen V,Anttila M,Lantta T

更新日期：2019-05-09 00:00:00

abstract：OBJECTIVE:The main aim of this case series report is to alert physicians to the occurrence of catatonia in Down syndrome (DS). A second aim is to stimulate the study of regression in DS and of catatonia. A subset of individuals with DS is noted to experience unexplained regression in behavior, mood, activities of daily...

journal_title：Neuropsychiatric disease and treatment

authors： Ghaziuddin N,Nassiri A,Miles JH

更新日期：2015-04-02 00:00:00

abstract：PURPOSE:Akathisia remains a common side effect especially from antipsychotic medication. If the condition is diagnosed the management options are limited. SUBJECTS/METHODOLOGY: We tested a structured relaxation program on nine patients with a diagnosis of schizophrenia suffering from akathisia. All patients were rated ...

journal_title：Neuropsychiatric disease and treatment

authors： Hansen LK,L'allemand T,Thiry F,Baldwin DS

更新日期：2010-05-25 00:00:00

abstract：:Developmental coordination disorder (DCD) is a common and well-recognized neurodevelopmental disorder affecting approximately 5 in every 100 individuals worldwide. It has long been included in standard national and international classifications of disorders (especially the Diagnostic and Statistical Manual of Mental D...

journal_title：Neuropsychiatric disease and treatment

authors： Biotteau M,Danna J,Baudou É,Puyjarinet F,Velay JL,Albaret JM,Chaix Y

更新日期：2019-07-08 00:00:00