Clinical correlates of complicated grief among individuals with acute coronary syndromes.

Abstract:

OBJECTIVE:The study aimed at exploring bereavement and complicated grief (CG) symptoms among subjects without a history of coronary heart disease (CHD) at the time of a first acute coronary syndrome (ACS) and to evaluate the relationship of CG symptoms and ACS. METHOD:Overall, 149 subjects with ACS (namely, acute myocardial infarct with or without ST-segment elevation or unstable angina), with no previous history of CHD, admitted to three cardiac intensive care units were included and evaluated by the Structured Clinical Interview for Complicated Grief (SCI-CG), Hamilton Depression Rating Scale, Hamilton Anxiety Rating Scale, and the 36-item Short-Form Health Survey (MOS-SF-36). RESULTS:Of the total sample of 149 subjects with ACS, 118 (79.2%) met criteria for DSM-5 persistent complex bereavement disorder. Among these, subjects who lost a partner, child, or sibling were older (P=0.008), less likely to be working (P=0.032), and more likely to be suffering from hypertension (P=0.021), returned higher scores on the SCI-CG (P=0.001) and developed the index ACS more frequently between 12 and 48 months after the death than those who lost a parent or another relative (P≤0.0001). The occurrence of ACS 12-48 months (P=0.019) after the loss was positively correlated with SCI-CG scores. An inverse relationship with SCI-CG scores was observed for patients who experienced ACS more than 48 months after the loss (P=0.005). The SCI-CG scores significantly predicted lower scores on the "general health" domain of MOS-SF-36 (P=0.030), as well as lower scores on "emotional well-being" domain (P=0.010). CONCLUSION:A great proportion of subjects with ACS report the loss of a loved one. Among these, the loss of a close relative and the severity of CG symptoms are associated with poorer health status. Our data corroborate previous data indicating a strong relationship between CG symptoms and severe cardiac problems.

authors

Pini S,Gesi C,Abelli M,Cardini A,Lari L,Felice F,Di Stefano R,Mazzotta G,Bovenzi F,Bertoli D,Borelli L,Michi P,Oligeri C,Balbarini A,Manicavasagar V

doi

10.2147/NDT.S87118

subject

Has Abstract

pub_date

2015-10-07 00:00:00

pages

2583-9

eissn

1176-6328

issn

1178-2021

pii

ndt-11-2583

journal_volume

11

pub_type

杂志文章
  • Adult neural stem cells: The promise of the future.

    abstract::Stem cells are self-renewing undifferentiated cells that give rise to multiple types of specialized cells of the body. In the adult, stem cells are multipotents and contribute to homeostasis of the tissues and regeneration after injury. Until recently, it was believed that the adult brain was devoid of stem cells, hen...

    journal_title:Neuropsychiatric disease and treatment

    pub_type: 杂志文章

    doi:10.2147/ndt.s2289

    authors: Taupin P

    更新日期:2007-12-01 00:00:00

  • Metabolite-related antidepressant action of diterpene ginkgolides in the prefrontal cortex.

    abstract:Purpose:Ginkgo biloba extract (GBE) contains diterpene ginkgolides (DGs), which have been shown to have neuroprotective effects by a number of previous studies. We previously demonstrated part of the action of DG. However, the impact of DG on the prefrontal cortex (PFC) remains unclear. Here, we evaluated the effects o...

    journal_title:Neuropsychiatric disease and treatment

    pub_type: 杂志文章

    doi:10.2147/NDT.S161351

    authors: Hu Q,Shen P,Bai S,Dong M,Liang Z,Chen Z,Wang W,Wang H,Gui S,Li P,Xie P

    更新日期:2018-04-13 00:00:00

  • Brain activity modification produced by a single radioelectric asymmetric brain stimulation pulse: a new tool for neuropsychiatric treatments. Preliminary fMRI study.

    abstract:PURPOSE:Radioelectric asymmetric brain stimulation technology with its treatment protocols has shown efficacy in various psychiatric disorders. The aim of this work was to highlight the mechanisms by which these positive effects are achieved. The current study was conducted to determine whether a single 500-millisecond...

    journal_title:Neuropsychiatric disease and treatment

    pub_type: 杂志文章

    doi:10.2147/NDT.S26123

    authors: Rinaldi S,Fontani V,Castagna A

    更新日期:2011-01-01 00:00:00

  • Disability in patients consulting for anxiety or mood disorders in primary care: response to antidepressant treatment.

    abstract:BACKGROUND:The primary objective of this prospective observational study was to evaluate changes in self-reported disability in patients with anxiety or mood disorders 3 months after initiating antidepressant treatment. METHODS:This study included 8396 patients consulting 2433 general practitioners in France for a maj...

    journal_title:Neuropsychiatric disease and treatment

    pub_type: 杂志文章

    doi:10.2147/NDT.S34132

    authors: Gérard A,Liard F,Crochard A,Goni S,Millet B

    更新日期:2012-01-01 00:00:00

  • Evidence for a Beneficial Effect of Oral N-acetylcysteine on Functional Outcomes and Inflammatory Biomarkers in Patients with Acute Ischemic Stroke.

    abstract:Purpose:Numerous preclinical studies have demonstrated the potential neuroprotective effects of N-acetylcysteine (NAC) in the treatment of brain ischemia. Accordingly, the present study aimed to assess the potential therapeutic effects of oral NAC in patients with acute ischemic stroke. Patients and Methods:In a rando...

    journal_title:Neuropsychiatric disease and treatment

    pub_type: 杂志文章

    doi:10.2147/NDT.S241497

    authors: Sabetghadam M,Mazdeh M,Abolfathi P,Mohammadi Y,Mehrpooya M

    更新日期:2020-05-18 00:00:00

  • Mycophenolate mofetil for myasthenia gravis: a clear and present controversy.

    abstract::Mycophenolate mofetil (MMF) has been used to treat myasthenia gravis (MG) for over 10 years. MMF's use in the MG population stems from its theoretical mechanism of action and the medical literature that supports its benefit in MG patients. Recently, two large, double-blinded, placebo-controlled, randomized clinical tr...

    journal_title:Neuropsychiatric disease and treatment

    pub_type: 杂志文章

    doi:10.2147/ndt.s3309

    authors: Heatwole C,Ciafaloni E

    更新日期:2008-12-01 00:00:00

  • Efficacy and safety of paliperidone palmitate 3-month versus 1-month formulation in patients with schizophrenia: comparison between European and non-European population.

    abstract:Purpose:This randomized, double-blind (DB), non-inferiority phase 3 study was conducted to assess the efficacy and safety of paliperidone palmitate 3-month (PP3M) vs 1-month formulation (PP1M) in European and non-European patients with schizophrenia. Patients and methods:In this randomized, DB, parallel-group study, a...

    journal_title:Neuropsychiatric disease and treatment

    pub_type: 杂志文章

    doi:10.2147/NDT.S189668

    authors: Savitz AJ,Xu H,Gopal S,Nuamah I,Ravenstijn P,Hough D,Hargarter L

    更新日期:2019-02-21 00:00:00

  • Psychotherapy and medication management strategies for obsessive-compulsive disorder.

    abstract::Obsessive-compulsive disorder (OCD) is a chronic anxiety disorder. While medication and psychotherapy advances have been very helpful to patients, many patients do not respond adequately to initial trials of serotonergic medication or cognitive-behavioral therapy (CBT) and require multiple treatment trials or combinat...

    journal_title:Neuropsychiatric disease and treatment

    pub_type: 杂志文章

    doi:10.2147/NDT.S13205

    authors: Walsh KH,McDougle CJ

    更新日期:2011-01-01 00:00:00

  • Assessing public speaking fear with the short form of the Personal Report of Confidence as a Speaker scale: confirmatory factor analyses among a French-speaking community sample.

    abstract:BACKGROUND:The main aim of this study was to assess the reliability and structural validity of the French version of the 12-item version of the Personal Report of Confidence as Speaker (PRCS), one of the most promising measurements of public speaking fear. METHODS:A total of 611 French-speaking volunteers were adminis...

    journal_title:Neuropsychiatric disease and treatment

    pub_type: 杂志文章

    doi:10.2147/NDT.S43097

    authors: Heeren A,Ceschi G,Valentiner DP,Dethier V,Philippot P

    更新日期:2013-01-01 00:00:00

  • Psychiatric comorbidity and suicide risk in patients with chronic migraine.

    abstract::The aim of this study was to explore the impact of mental illness among patients with migraine. We performed MedLine and PsycINFO searches from 1980 to 2008. Research has systematically documented a strong bidirectional association between migraine and psychiatric disorders. The relationship between migraine and psych...

    journal_title:Neuropsychiatric disease and treatment

    pub_type: 杂志文章

    doi:10.2147/ndt.s8467

    authors: Pompili M,Serafini G,Di Cosimo D,Dominici G,Innamorati M,Lester D,Forte A,Girardi N,De Filippis S,Tatarelli R,Martelletti P

    更新日期:2010-04-07 00:00:00

  • Twelve-week physical exercise does not have a long-lasting effect on kynurenines in plasma of depressed patients.

    abstract:BACKGROUND:Physical exercise has well-characterized positive effects on depressive symptoms. The underlying biologic mechanisms are, however, far from established. A recently discovered mechanism has linked the enhanced conversion of kynurenine to kynurenic acid (KYNA) to an increased resilience toward stress-induced d...

    journal_title:Neuropsychiatric disease and treatment

    pub_type: 杂志文章

    doi:10.2147/NDT.S131746

    authors: Millischer V,Erhardt S,Ekblom Ö,Forsell Y,Lavebratt C

    更新日期:2017-03-31 00:00:00

  • Early predictors of brain damage in full-term newborns with hypoxic ischemic encephalopathy.

    abstract:OBJECTIVE OF THE STUDY:To evaluate the value of serum creatine phosphokinase-brain specific (CK-BB) and urinary lactate/creatinine (L/C) ratio as early indicators of brain damage in full-term newborns with hypoxic ischemic encephalopathy (HIE). PATIENTS AND METHODS:A case-control study including 25 full-term new-born ...

    journal_title:Neuropsychiatric disease and treatment

    pub_type: 杂志文章

    doi:10.2147/NDT.S144225

    authors: Alkholy UM,Abdalmonem N,Zaki A,Ali YF,Mohamed SA,Abdelsalam NI,Hashim MIA,Sekkien MA,Elsherbiny YM

    更新日期:2017-08-08 00:00:00

  • Abnormal intrinsic functional hubs in alcohol dependence: evidence from a voxelwise degree centrality analysis.

    abstract:OBJECTIVE:To explore the abnormal intrinsic functional hubs in alcohol dependence using voxelwise degree centrality analysis approach, and their relationships with clinical features. MATERIALS AND METHODS:Twenty-four male alcohol dependence subjects free of medicine (mean age, 50.21±9.62 years) and 24 age- and educati...

    journal_title:Neuropsychiatric disease and treatment

    pub_type: 杂志文章

    doi:10.2147/NDT.S142742

    authors: Luo X,Guo L,Dai XJ,Wang Q,Zhu W,Miao X,Gong H

    更新日期:2017-07-28 00:00:00

  • Optimal management of ADHD in older adults.

    abstract:BACKGROUND:The manifestation of attention-deficit/hyperactivity disorder (ADHD) among older adults has become an interesting topic of interest due to an increasing number of adults aged 50 years and older (≥50 years) seeking assessment for ADHD. Unfortunately, there is a lack of research on ADHD in older adults, and un...

    journal_title:Neuropsychiatric disease and treatment

    pub_type: 杂志文章,评审

    doi:10.2147/NDT.S59271

    authors: Torgersen T,Gjervan B,Lensing MB,Rasmussen K

    更新日期:2016-01-08 00:00:00

  • Drug-drug interactions involving antidepressants: focus on desvenlafaxine.

    abstract::Psychiatric and physical conditions often coexist, and there is robust evidence that associates the frequency of depression with single and multiple physical conditions. More than half of patients with depression may have at least one chronic physical condition. Therefore, antidepressants are often used in cotherapy w...

    journal_title:Neuropsychiatric disease and treatment

    pub_type: 杂志文章,评审

    doi:10.2147/NDT.S157708

    authors: Low Y,Setia S,Lima G

    更新日期:2018-02-19 00:00:00

  • Reproductive life events and Alzheimer's disease in Italian women: a retrospective study.

    abstract::The aim of our study was to understand the complex relationship between the major reproductive life events in women with Alzheimer's disease. In a retrospective, case-control study, 275 women with Alzheimer's disease (AD) and 276 control patients from a hospital population were enrolled from July 2007 to December 2010...

    journal_title:Neuropsychiatric disease and treatment

    pub_type: 杂志文章

    doi:10.2147/NDT.S36622

    authors: Zucchella C,Sinforiani E,Citterio A,Giarracca V,Bono G,Mauri M

    更新日期:2012-01-01 00:00:00

  • Levetiracetam in the treatment of childhood epilepsy.

    abstract::Epilepsy is a common pediatric neurologic disorder that is difficult to manage in a substantial portion of children. Levetiracetam (LEV) is a novel antiepileptic drug (AED) that has recently been approved as add-on treatment for various seizure types in epilepsy populations that include children: for refractory partia...

    journal_title:Neuropsychiatric disease and treatment

    pub_type: 杂志文章

    doi:

    authors: Wheless JW

    更新日期:2007-08-01 00:00:00

  • High relapse rate and poor medication adherence in the Chinese population with schizophrenia: results from an observational survey in the People's Republic of China.

    abstract:BACKGROUND:Relapse is common in schizophrenia, and seriously impacts patients' quality of life and social functioning. Many factors have been identified that may potentially increase the risk of relapse. This study was designed to investigate the relapse rate in the year following hospital discharge among Chinese patie...

    journal_title:Neuropsychiatric disease and treatment

    pub_type: 杂志文章

    doi:10.2147/NDT.S72367

    authors: Xiao J,Mi W,Li L,Shi Y,Zhang H

    更新日期:2015-05-08 00:00:00

  • CXCL13 Is A Biomarker Of Anti-Leucine-Rich Glioma-Inactivated Protein 1 Encephalitis Patients.

    abstract:Background:Although antibody-mediated immune responses are considered pathogenic and responsible for neural injury in anti-leucine-rich glioma-inactivated protein 1 (anti-LGI1) encephalitis, previous studies have indicated that cytokines and chemokines might play roles in the pathogenic process by serving as B cell enh...

    journal_title:Neuropsychiatric disease and treatment

    pub_type: 杂志文章

    doi:10.2147/NDT.S222258

    authors: Lin YT,Yang X,Lv JW,Liu XW,Wang SJ

    更新日期:2019-10-11 00:00:00

  • Spectrum of epilepsy - prevalence, impact, and treatment gap: an epidemiological study from Al-Quseir, Egypt.

    abstract:BACKGROUND:Epidemiology continues to be an important research tool in the study of epilepsy and related disorders, providing a better understanding of the frequency, causes, and natural history of the disorder. OBJECTIVE:To estimate the prevalence of epilepsy in Al-Quseir, Red Sea Governorate, Egypt, and its magnitude...

    journal_title:Neuropsychiatric disease and treatment

    pub_type: 杂志文章

    doi:10.2147/NDT.S87765

    authors: El-Tallawy HN,Farghaly WM,Rageh TA,Shehata GA,Metwally NA,Badry R,Sayed MA,Abdelwarith AM,Kandil MR,Hamed MA,Mohamed KO,Tohamy AM

    更新日期:2016-05-12 00:00:00

  • Reduction in apathy following epilepsy surgery.

    abstract:Introduction:Surgical treatment for patients with epilepsy who do not respond to antiepileptic medication can lead to changes in behavior, including new onset of neuropsychiatric symptoms such as depression and anxiety. In other cases, neuropsychiatric symptoms present before surgery may be alleviated. Because applicat...

    journal_title:Neuropsychiatric disease and treatment

    pub_type: 杂志文章

    doi:10.2147/NDT.S189603

    authors: Mah L,Swearer J,Phillips CA,Benjamin S

    更新日期:2019-06-28 00:00:00

  • Erratum: Influence of dose, gender, and cigarette smoking on clozapine plasma concentrations [Corrigendum].

    abstract::[This corrects the article on p. 1535 in vol. 14, PMID: 29950838.]. ...

    journal_title:Neuropsychiatric disease and treatment

    pub_type: 杂志文章,已发布勘误

    doi:10.2147/NDT.S205205

    authors:

    更新日期:2019-03-05 00:00:00

  • Shen-Qi-Jie-Yu-Fang exerts effects on a rat model of postpartum depression by regulating inflammatory cytokines and CD4(+)CD25(+) regulatory T cells.

    abstract:BACKGROUND:Shen-Qi-Jie-Yu-Fang (SJF) is composed of eight Chinese medicinal herbs. It is widely used in traditional Chinese medicine for treating postpartum depression (PPD). Previous studies have shown that SJF treats PPD through the neuroendocrine mechanism. AIM:To further investigate the effect of SJF on the immune...

    journal_title:Neuropsychiatric disease and treatment

    pub_type: 杂志文章

    doi:10.2147/NDT.S98131

    authors: Li J,Zhao R,Li X,Sun W,Qu M,Tang Q,Yang X,Zhang S

    更新日期:2016-04-15 00:00:00

  • Errorless learning and spaced retrieval techniques to relearn instrumental activities of daily living in mild Alzheimer's disease: A case report study.

    abstract::Previous studies on cognitive training in Alzheimer's disease (AD) were principally aimed at making patients learn items not related to functional needs. However, AD patients also experience difficulties with instrumental activities of daily living (IADL). The goal of the present multiple baseline case report study wa...

    journal_title:Neuropsychiatric disease and treatment

    pub_type:

    doi:10.2147/ndt.s3684

    authors: Thivierge S,Simard M,Jean L,Grandmaison E

    更新日期:2008-10-01 00:00:00

  • A review of ketamine's role in ECT and non-ECT settings.

    abstract::Up to 20% of depressed patients demonstrate treatment resistance to one or more adequate antidepressant trials, resulting in a disproportionately high burden of illness. Ketamine is a non-barbiturate, rapid-acting general anesthetic that has been increasingly studied in treatment resistant depression (TRD), typically ...

    journal_title:Neuropsychiatric disease and treatment

    pub_type: 杂志文章,评审

    doi:10.2147/NDT.S157233

    authors: Jankauskas V,Necyk C,Chue J,Chue P

    更新日期:2018-06-06 00:00:00

  • Affect regulation: a systems neuroscience perspective.

    abstract:OBJECTIVE:TO INTEGRATE: (1) the neuroanatomical model of affect regulation; (2) a functional model of affect regulation; and (3) the evolving picture of affect dysregulation as exemplified by bipolar disorder. METHODOLOGY:A computerized search for articles on related topics was augmented by additional selected studies...

    journal_title:Neuropsychiatric disease and treatment

    pub_type: 杂志文章

    doi:10.2147/nedt.1.1.9.52299

    authors: Pavuluri MN,Herbener ES,Sweeney JA

    更新日期:2005-03-01 00:00:00

  • Imitation and communication skills development in children with pervasive developmental disorders.

    abstract::This study evaluates the correlation between failure to develop spontaneous imitation and language skills in pervasive developmental disorders. Sixty-four children between the age of 3 and 8 years were assessed using the Autism Diagnostic Interview-Revised (ADI-R), the Childhood Autism Rating Scale (CARS), and the Aut...

    journal_title:Neuropsychiatric disease and treatment

    pub_type: 杂志文章

    doi:10.2147/ndt.s5679

    authors: De Giacomo A,Portoghese C,Martinelli D,Fanizza I,L'abate L,Margari L

    更新日期:2009-01-01 00:00:00

  • Reliability and validity of the Depression and Somatic Symptoms Scale among patients with chronic low back pain.

    abstract:Background:The Depression and Somatic Symptoms Scale (DSSS), which is a free scale that includes a depression subscale (DS) and a somatic subscale (SS), was developed to evaluate depression and somatic symptoms simultaneously. This study aimed to examine the reliability and validity of the DSSS among patients with chro...

    journal_title:Neuropsychiatric disease and treatment

    pub_type: 杂志文章

    doi:10.2147/NDT.S188277

    authors: Liu CH,Fu TS,Lee CP,Hung CI

    更新日期:2019-01-14 00:00:00

  • Atypical depression: current perspectives.

    abstract::The history and present status of the definition, prevalence, neurobiology, and treatment of atypical depression (AD) is presented. The concept of AD has evolved through the years, and currently, in Diagnostic and Statistical Manual of Mental Disorders (DSM), Fifth Edition, the specifier of depressive episode with aty...

    journal_title:Neuropsychiatric disease and treatment

    pub_type: 杂志文章,评审

    doi:10.2147/NDT.S147317

    authors: Łojko D,Rybakowski JK

    更新日期:2017-09-20 00:00:00

  • Relationship between apathy and tumor location, size, and brain edema in patients with intracranial meningioma.

    abstract:BACKGROUND:The purpose of this study is to assess the relationship between apathy and tumor location, size, and brain edema in patients with intracranial meningioma. METHODS:We enrolled 65 consecutive patients with meningioma and 31 normal controls matched for age, gender, and education. The patients were divided into...

    journal_title:Neuropsychiatric disease and treatment

    pub_type: 杂志文章

    doi:10.2147/NDT.S85288

    authors: Peng Y,Shao C,Gong Y,Wu X,Tang W,Shi S

    更新日期:2015-07-13 00:00:00