Drug-drug interactions involving antidepressants: focus on desvenlafaxine.

Abstract:

:Psychiatric and physical conditions often coexist, and there is robust evidence that associates the frequency of depression with single and multiple physical conditions. More than half of patients with depression may have at least one chronic physical condition. Therefore, antidepressants are often used in cotherapy with other medications for the management of both psychiatric and chronic physical illnesses. The risk of drug-drug interactions (DDIs) is augmented by complex polypharmacy regimens and extended periods of treatment required, of which possible outcomes range from tolerability issues to lack of efficacy and serious adverse events. Optimal patient outcomes may be achieved through drug selection with minimal potential for DDIs. Desvenlafaxine is a serotonin-norepinephrine reuptake inhibitor approved for the treatment of adults with major depressive disorder. Pharmacokinetic studies of desvenlafaxine have shown a simple metabolic profile unique among antidepressants. This review examines the DDI profiles of antidepressants, particularly desvenlafaxine, in relation to drugs of different therapeutic areas. The summary and comparison of information available is meant to help clinicians in making informed decisions when using desvenlafaxine in patients with depression and comorbid chronic conditions.

authors

Low Y,Setia S,Lima G

doi

10.2147/NDT.S157708

subject

Has Abstract

pub_date

2018-02-19 00:00:00

pages

567-580

eissn

1176-6328

issn

1178-2021

pii

ndt-14-567

journal_volume

14

pub_type

杂志文章,评审
  • The association of post-stroke anhedonia with salivary cortisol levels and stroke lesion in hippocampal/parahippocampal region.

    abstract:BACKGROUND:Anhedonia constitutes a coherent construct, with neural correlates and negative clinical impact, independent of depression. However, little is known about the neural correlates of anhedonia in stroke patients. In this study, we investigated the association of post-stroke anhedonia with salivary cortisol leve...

    journal_title:Neuropsychiatric disease and treatment

    pub_type: 杂志文章

    doi:10.2147/NDT.S73722

    authors: Terroni L,Amaro E Jr,Iosifescu DV,Mattos P,Yamamoto FI,Tinone G,Conforto AB,Sobreiro MF,Guajardo VD,De Lucia MC,Moreira AC,Scaff M,Leite CC,Fraguas R

    更新日期:2015-02-03 00:00:00

  • Changes of serum uric acid and total bilirubin in elderly patients with major postischemic stroke depression.

    abstract:Background:This was a longitudinal study which investigated the relationship between serum uric acid (SUA) and total bilirubin (Tbil) upon admission in elderly stroke patients and the occurrence of postischemic stroke depression (IPSD) at 3, 6, and 9 months of post-stroke follow-up. Subjects and methods:Data were anal...

    journal_title:Neuropsychiatric disease and treatment

    pub_type: 杂志文章

    doi:10.2147/NDT.S149712

    authors: Gao J,Xu W,Han K,Zhu L,Gao L,Shang X

    更新日期:2017-12-27 00:00:00

  • Unmet needs in the management of schizophrenia.

    abstract::Studies on unmet needs during the last decades have played a significant role in the development and dissemination of evidence-based community practices for persistent schizophrenia and other severe mental disorders. This review has thoroughly considered several blocks of unmet needs, which are frequently related to s...

    journal_title:Neuropsychiatric disease and treatment

    pub_type: 杂志文章,评审

    doi:10.2147/NDT.S41063

    authors: Torres-González F,Ibanez-Casas I,Saldivia S,Ballester D,Grandón P,Moreno-Küstner B,Xavier M,Gómez-Beneyto M

    更新日期:2014-01-16 00:00:00

  • Reduction in apathy following epilepsy surgery.

    abstract:Introduction:Surgical treatment for patients with epilepsy who do not respond to antiepileptic medication can lead to changes in behavior, including new onset of neuropsychiatric symptoms such as depression and anxiety. In other cases, neuropsychiatric symptoms present before surgery may be alleviated. Because applicat...

    journal_title:Neuropsychiatric disease and treatment

    pub_type: 杂志文章

    doi:10.2147/NDT.S189603

    authors: Mah L,Swearer J,Phillips CA,Benjamin S

    更新日期:2019-06-28 00:00:00

  • Natural reduced water suppressed anxiety and protected the heightened oxidative stress in rats.

    abstract:BACKGROUND:In Japan, the effects of reduced water, such as hydrogen-rich electrolyzed reduced water and natural reduced water, like Hita Tenryosui water®, have been examined. The purpose of the present study was to identify the role of natural reduced water in anxiety and blood biochemical analysis. MATERIALS AND METH...

    journal_title:Neuropsychiatric disease and treatment

    pub_type: 杂志文章

    doi:10.2147/NDT.S138289

    authors: Masuda K,Tanaka Y,Kanehisa M,Ninomiya T,Inoue A,Higuma H,Kawashima C,Nakanishi M,Okamoto K,Akiyoshi J

    更新日期:2017-09-08 00:00:00

  • Korean Medication Algorithm Project for Bipolar Disorder: third revision.

    abstract:OBJECTIVE:To constitute the third revision of the guidelines for the treatment of bipolar disorder issued by the Korean Medication Algorithm Project for Bipolar Disorder (KMAP-BP 2014). METHODS:A 56-item questionnaire was used to obtain the consensus of experts regarding pharmacological treatment strategies for the va...

    journal_title:Neuropsychiatric disease and treatment

    pub_type: 杂志文章

    doi:10.2147/NDT.S77838

    authors: Woo YS,Lee JG,Jeong JH,Kim MD,Sohn I,Shim SH,Jon DI,Seo JS,Shin YC,Min KJ,Yoon BH,Bahk WM

    更新日期:2015-02-26 00:00:00

  • Lithium and neuroprotection: translational evidence and implications for the treatment of neuropsychiatric disorders.

    abstract::In the last two decades, a growing body of evidence has shown that lithium has several neuroprotective effects. Several neurobiological mechanisms have been proposed to underlie these clinical effects. Evidence from preclinical studies suggests that neuroprotection induced by lithium is mainly related to its potent in...

    journal_title:Neuropsychiatric disease and treatment

    pub_type: 杂志文章

    doi:10.2147/NDT.S33086

    authors: Diniz BS,Machado-Vieira R,Forlenza OV

    更新日期:2013-01-01 00:00:00

  • Structured relaxation in the treatment of akathisia: case series.

    abstract:PURPOSE:Akathisia remains a common side effect especially from antipsychotic medication. If the condition is diagnosed the management options are limited. SUBJECTS/METHODOLOGY: We tested a structured relaxation program on nine patients with a diagnosis of schizophrenia suffering from akathisia. All patients were rated ...

    journal_title:Neuropsychiatric disease and treatment

    pub_type: 杂志文章

    doi:10.2147/ndt.s9810

    authors: Hansen LK,L'allemand T,Thiry F,Baldwin DS

    更新日期:2010-05-25 00:00:00

  • Functional neuroimaging of traumatic brain injury: advances and clinical utility.

    abstract::Functional deficits due to traumatic brain injury (TBI) can have significant and enduring consequences upon patients' life quality and expectancy. Although functional neuroimaging is essential for understanding TBI pathophysiology, an insufficient amount of effort has been dedicated to the task of translating function...

    journal_title:Neuropsychiatric disease and treatment

    pub_type: 杂志文章,评审

    doi:10.2147/NDT.S79174

    authors: Irimia A,Van Horn JD

    更新日期:2015-09-15 00:00:00

  • Heme oxygenase-1 induction in the brain during lipopolysaccharide-induced acute inflammation.

    abstract::Delirium occurs in 23% of sepsis patients, in which pro-inflammatory cytokines and nitric oxide are suggested to be involved. However, in animal experiments, even a subseptic dose of lipopolysaccharide (LPS) injection induces both pro-inflammatory cytokines and inducible nitric oxide synthase in the brain, suggesting ...

    journal_title:Neuropsychiatric disease and treatment

    pub_type: 杂志文章

    doi:10.2147/ndt.s3063

    authors: Maeda S,Nakatsuka I,Hayashi Y,Higuchi H,Shimada M,Miyawaki T

    更新日期:2008-06-01 00:00:00

  • Atrophic Corpus Callosum Associated with Altered Functional Asymmetry in Major Depressive Disorder.

    abstract:Purpose:Impairments in intra- and inter-hemispheric information transfer circuits have been reported in patients with major depressive disorder (MDD). However, the specific anomalous connection (intra- and/or inter-hemispheric) and hemisphere (left and/or right) in which this connection plays a more dominant role in th...

    journal_title:Neuropsychiatric disease and treatment

    pub_type: 杂志文章

    doi:10.2147/NDT.S245078

    authors: Ran S,Zuo Z,Li C,Yin X,Qu W,Tang Q,Wang Y,Shi Y,Li H

    更新日期:2020-06-10 00:00:00

  • Update on once-daily zonisamide monotherapy in partial seizures.

    abstract::Zonisamide is an antiepileptic drug that is structurally different from other antiepileptic agents. Its long half-life, once-daily dosing, lack of induction of hepatic enzymes, and broad spectrum of action makes it a suitable candidate for monotherapy. It has been approved as monotherapy for partial onset epilepsy in ...

    journal_title:Neuropsychiatric disease and treatment

    pub_type: 杂志文章,评审

    doi:10.2147/NDT.S39152

    authors: Afra P,Adamolekun B

    更新日期:2014-03-19 00:00:00

  • Effectiveness and tolerability of transdermal rivastigmine in the treatment of Alzheimer's disease in daily practice.

    abstract:BACKGROUND:Oral cholinesterase inhibitors at doses efficacious for the treatment of Alzheimer's disease (AD) are often prematurely discontinued due to gastrointestinal side effects. In controlled clinical trials, transdermal rivastigmine demonstrated less such effects at similar efficacy. The current study aimed to ver...

    journal_title:Neuropsychiatric disease and treatment

    pub_type: 杂志文章

    doi:10.2147/NDT.S29116

    authors: Seibert J,Tracik F,Articus K,Spittler S

    更新日期:2012-01-01 00:00:00

  • Celiac plexus neurolysis for the treatment of upper abdominal cancer pain.

    abstract::Optimal treatment of oncologic pain is a challenge to all professionals who deal with cancer and its complications. The management of upper abdominal pain is usually difficult and it is often refractory to conservative therapies. In this context, celiac plexus neurolysis (CPN) appears to be an important and indispensa...

    journal_title:Neuropsychiatric disease and treatment

    pub_type: 杂志文章

    doi:10.2147/NDT.S43730

    authors: Teixeira MJ,Neto ER,da Nóbrega JC,Dos Ângelos JS,Martin MS,de Monaco BA,Fonoff ET

    更新日期:2013-01-01 00:00:00

  • Associations among depressive symptoms, childhood abuse, neuroticism, and adult stressful life events in the general adult population.

    abstract:BACKGROUND:Recent studies have suggested that the interactions among several factors affect the onset, progression, and prognosis of major depressive disorder. This study investigated how childhood abuse, neuroticism, and adult stressful life events interact with one another and affect depressive symptoms in the genera...

    journal_title:Neuropsychiatric disease and treatment

    pub_type: 杂志文章

    doi:10.2147/NDT.S128557

    authors: Ono K,Takaesu Y,Nakai Y,Shimura A,Ono Y,Murakoshi A,Matsumoto Y,Tanabe H,Kusumi I,Inoue T

    更新日期:2017-02-15 00:00:00

  • Frequency of inborn errors of metabolism screening for children with unexplained acute encephalopathy at an emergency department.

    abstract:Objective:Our study aimed to estimate the frequency of inborn errors of metabolism (IEMs) in patients presenting with acute encephalopathy-like picture at an emergency department (ED). Subjects and methods:Our study was a prospective observational study conducted on 30 patients admitted to the pediatric ED with unexpl...

    journal_title:Neuropsychiatric disease and treatment

    pub_type: 杂志文章

    doi:10.2147/NDT.S165833

    authors: Abdel Maksoud M,ELsayed SM,Shatla RH,Imam AA,Elsayed RM,Mosabah AA,Sherif AM

    更新日期:2018-06-29 00:00:00

  • Review: management of Parkinson's disease.

    abstract::Parkinson's disease (PD) is one of the most frequent neurological diseases. Despite the modern imaging and nuclear techniques which help to diagnose it in a very early stage and lead to a better discrimination of similar diseases, PD has remained a clinical diagnosis. The increasing number of available treatment optio...

    journal_title:Neuropsychiatric disease and treatment

    pub_type: 杂志文章

    doi:10.2147/NDT.S32302

    authors: Pedrosa DJ,Timmermann L

    更新日期:2013-01-01 00:00:00

  • Complex obsessive compulsive and impulsive symptoms in Tourette's syndrome.

    abstract::Obsessive compulsive and impulsive symptoms are prevalent in patients with Tourette's Syndrome (TS) and well recognized as part of the TS spectrum. However, some complex obsessive compulsive and impulsive behaviors may be mistaken for other symptoms, such as complex tics or psychotic behavior. In addition, the overlap...

    journal_title:Neuropsychiatric disease and treatment

    pub_type:

    doi:

    authors: Palumbo D,Kurlan R

    更新日期:2007-01-01 00:00:00

  • Dissociative Symptoms and Self-Reported Childhood and Current Trauma in Male Incarcerated People with Borderline Personality Disorder - Results from a Small Cross-Sectional Study in Iran.

    abstract:Background:There is evidence that incarcerated people show higher rates of symptoms of psychopathology. In the present study, we assessed male Iranian incarcerated people with borderline personality disorders (BPD) and investigated the occurrence of past and current trauma and their associations with dissociative exper...

    journal_title:Neuropsychiatric disease and treatment

    pub_type: 杂志文章

    doi:10.2147/NDT.S266016

    authors: Golshani S,Ghanbari S,Firoozabadi A,Shakeri J,Hookari S,Rahami B,Sadeghi Bahmani D,Brand S

    更新日期:2020-10-21 00:00:00

  • Management of refractory complex partial seizures: current state of the art.

    abstract::Diagnosis of complex partial epilepsy is based on the clinical history, and laboratory tests, including EEG and neuroimaging studies, corroborate the diagnosis. The goal of epilepsy management is to make the patient completely seizure-free without drug-induced side effects, even in the patient with refractory complex ...

    journal_title:Neuropsychiatric disease and treatment

    pub_type: 杂志文章

    doi:10.2147/ndt.s4489

    authors: Treiman DM

    更新日期:2010-06-24 00:00:00

  • Below and beyond the recognition of emotional facial expressions in alcohol dependence: from basic perception to social cognition.

    abstract::Studies that have carried out experimental evaluation of emotional skills in alcohol-dependence have, up to now, been mainly focused on the exploration of emotional facial expressions (EFE) decoding. In the present paper, we provide some complements to the recent systematic literature review published by Donadon and d...

    journal_title:Neuropsychiatric disease and treatment

    pub_type: 杂志文章

    doi:10.2147/NDT.S74963

    authors: D'Hondt F,Campanella S,Kornreich C,Philippot P,Maurage P

    更新日期:2014-11-18 00:00:00

  • Evaluation of BPPV with vertebral artery values.

    abstract:Objectives:The aim of this study was to investigate the association between benign paroxysmal positional vertigo (BPPV) and vertebral artery (VA) flow rates and diameters by using Doppler ultrasonography in patients with BPPV. Additionally, we aimed to investigate the abnormalities of VA values obtained by extracranial...

    journal_title:Neuropsychiatric disease and treatment

    pub_type: 杂志文章

    doi:10.2147/NDT.S169991

    authors: Yazıcı A,İnanç Y

    更新日期:2018-08-06 00:00:00

  • Role of SIRT1/PGC-1α in mitochondrial oxidative stress in autistic spectrum disorder.

    abstract::Autistic spectrum disorder (ASD) is a neurodevelopmental disorder and has a high prevalence in children. Recently, mitochondrial oxidative stress has been proposed to be associated with ASD. Besides, SIRT1/PGC-1α signaling plays an important role in combating oxidative stress. In this study, we sought to determine the...

    journal_title:Neuropsychiatric disease and treatment

    pub_type: 杂志文章

    doi:10.2147/NDT.S129081

    authors: Bu X,Wu,Lu X,Yang L,Xu X,Wang J,Tang J

    更新日期:2017-06-23 00:00:00

  • Cost-utility of collaborative care for the treatment of comorbid major depressive disorder in outpatients with chronic physical conditions. A randomized controlled trial in the general hospital setting (CC-DIM).

    abstract:PURPOSE:Major depressive disorder (MDD) is highly prevalent in patients with a chronic physical condition, and this comorbidity has a negative influence on quality of life, health care costs, self-care, morbidity, and mortality. Research has shown that collaborative care (CC) may be a cost-effective treatment. However,...

    journal_title:Neuropsychiatric disease and treatment

    pub_type: 杂志文章

    doi:10.2147/NDT.S134008

    authors: Goorden M,van der Feltz-Cornelis CM,van Steenbergen-Weijenburg KM,Horn EK,Beekman AT,Hakkaart-van Roijen L

    更新日期:2017-07-18 00:00:00

  • Deep brain stimulation in Tourette's syndrome: evidence to date.

    abstract::Tourette's syndrome (TS) is a neurodevelopmental disorder that comprises vocal and motor tics associated with a high frequency of psychiatric comorbidities, which has an important impact on quality of life. The onset is mainly in childhood and the symptoms can either fade away or require pharmacological therapies asso...

    journal_title:Neuropsychiatric disease and treatment

    pub_type: 杂志文章,评审

    doi:10.2147/NDT.S139368

    authors: Casagrande SCB,Cury RG,Alho EJL,Fonoff ET

    更新日期:2019-04-29 00:00:00

  • Adjunctive treatment for cognitive impairment in patients with chronic schizophrenia: a double-blind, placebo-controlled study.

    abstract::Cognitive impairment is closely related to real-life functioning in patients with schizophrenia. The aim of the present study was to evaluate the effects of adjunctive treatment with donepezil on cognition in patients with chronic schizophrenia. This was a 12-week, double-blind, randomized, placebo-controlled study of...

    journal_title:Neuropsychiatric disease and treatment

    pub_type: 杂志文章

    doi:10.2147/NDT.S64189

    authors: Zhu W,Zhang Z,Qi J,Liu F,Chen J,Zhao J,Guo X

    更新日期:2014-07-14 00:00:00

  • Mycophenolate mofetil for myasthenia gravis: a clear and present controversy.

    abstract::Mycophenolate mofetil (MMF) has been used to treat myasthenia gravis (MG) for over 10 years. MMF's use in the MG population stems from its theoretical mechanism of action and the medical literature that supports its benefit in MG patients. Recently, two large, double-blinded, placebo-controlled, randomized clinical tr...

    journal_title:Neuropsychiatric disease and treatment

    pub_type: 杂志文章

    doi:10.2147/ndt.s3309

    authors: Heatwole C,Ciafaloni E

    更新日期:2008-12-01 00:00:00

  • Bupropion interferes with the image diagnosis of Parkinson's disease.

    abstract::Major depressive disorder (MDD) and Parkinson's disease (PD) share symptoms such as tremor. Bupropion, a norepinephrine-dopamine reuptake inhibitor, shows weak dopamine transporter (DAT) occupancy. We report here on a patient with MDD whose hand tremors might have been misdiagnosed as PD by single-photon emission comp...

    journal_title:Neuropsychiatric disease and treatment

    pub_type:

    doi:10.2147/NDT.S150912

    authors: Lin CH,Lane HY

    更新日期:2017-10-19 00:00:00

  • HPA-axis genes as potential risk variants for neurocognitive decline in trauma-exposed, HIV-positive females.

    abstract:Purpose:Previous studies have independently provided evidence for the effects of HIV infection, hypothalamic-pituitary-adrenal (HPA) axis dysfunction and early life trauma on neurocognitive impairment (NCI). This study examined the interaction between single-nucleotide polymorphisms (SNPs) of two HPA axis genes, cortic...

    journal_title:Neuropsychiatric disease and treatment

    pub_type: 杂志文章

    doi:10.2147/NDT.S166992

    authors: Jacobs S,Moxley K,Womersley JS,Spies G,Hemmings SM,Seedat S

    更新日期:2018-09-28 00:00:00

  • Sexual dysfunction, mood, anxiety, and personality disorders in female patients with fibromyalgia.

    abstract:BACKGROUND:We aimed to investigate the current prevalence of sexual dysfunction (SD), mood, anxiety, and personality disorders in female patients with fibromyalgia (FM). METHODS:This case-control study involved 96 patients with FM and 94 healthy women. The SD diagnosis was based on a psychiatric interview in accordanc...

    journal_title:Neuropsychiatric disease and treatment

    pub_type: 杂志文章

    doi:10.2147/NDT.S99160

    authors: Kayhan F,Küçük A,Satan Y,İlgün E,Arslan Ş,İlik F

    更新日期:2016-02-16 00:00:00